#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P26449 uniprotkb:P26309 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269058|imex:IM-19342-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 - crc64:0BDFB8697935BCEB crc64:CCE7CD149C1F5ACF agonist:Nocodazole - activates the spindle checkpoint.|complex-properties:MW = 670 kDa|figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:606C91EF6D3C4036|rigid:eKm9aA2qIRqyEfeLJt8KzzFd7Ng false myc tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26449 uniprotkb:P38042 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4249|uniprotkb:D6VPS0|ensemblfungi:YBL084C psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc27_yeast(display_long)|uniprotkb:APC3(gene name synonym)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:SNB1(gene name synonym)|uniprotkb:YBL084C(locus name)|uniprotkb:YBL0718(orf name)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269058|imex:IM-19342-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_009469.2|sgd:S000000180|ensemblfungi:YBL084C(gene)|ensemblfungi:YBL084C_mRNA(transcript)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|dip:DIP-796N|mint:P38042|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SCE-983168 - crc64:0BDFB8697935BCEB crc64:A1ECA067AF8784E3 agonist:Nocodazole - activates the spindle checkpoint.|complex-properties:MW = 670 kDa|figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:ixEaqMTOirQhvsr/UDvyQtVYLqQ559292 intact-crc:606C91EF6D3C4036|rigid:eKm9aA2qIRqyEfeLJt8KzzFd7Ng false myc tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26449 uniprotkb:P47074 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269058|imex:IM-19342-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - crc64:0BDFB8697935BCEB crc64:36550249D81BB6D1 agonist:Nocodazole - activates the spindle checkpoint.|complex-properties:MW = 670 kDa|figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:606C91EF6D3C4036|rigid:eKm9aA2qIRqyEfeLJt8KzzFd7Ng false myc tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26449 uniprotkb:P26309 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269075|imex:IM-19342-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 - crc64:0BDFB8697935BCEB crc64:CCE7CD149C1F5ACF agonist:Nocodazole - activates the spindle checkpoint.|complex-properties:MW = 670 kDa|figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:01575C583767DB00|rigid:BS7o+qNbuW6ll5NpcR6RJkGuQXA false myc tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26449 uniprotkb:P38042 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4249|uniprotkb:D6VPS0|ensemblfungi:YBL084C psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc27_yeast(display_long)|uniprotkb:APC3(gene name synonym)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:SNB1(gene name synonym)|uniprotkb:YBL084C(locus name)|uniprotkb:YBL0718(orf name)|uniprotkb:Cell division control protein 27(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269075|imex:IM-19342-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_009469.2|sgd:S000000180|ensemblfungi:YBL084C(gene)|ensemblfungi:YBL084C_mRNA(transcript)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|dip:DIP-796N|mint:P38042|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SCE-983168 - crc64:0BDFB8697935BCEB crc64:A1ECA067AF8784E3 agonist:Nocodazole - activates the spindle checkpoint.|complex-properties:MW = 670 kDa|figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:ixEaqMTOirQhvsr/UDvyQtVYLqQ559292 intact-crc:01575C583767DB00|rigid:BS7o+qNbuW6ll5NpcR6RJkGuQXA false myc tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26449 uniprotkb:P40958 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:"MI:0071"(molecular sieving) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269075|imex:IM-19342-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 - crc64:0BDFB8697935BCEB - agonist:Nocodazole - activates the spindle checkpoint.|complex-properties:MW = 670 kDa|figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 intact-crc:01575C583767DB00|rigid:BS7o+qNbuW6ll5NpcR6RJkGuQXA false myc tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26449 uniprotkb:P47074 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269075|imex:IM-19342-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - crc64:0BDFB8697935BCEB crc64:36550249D81BB6D1 agonist:Nocodazole - activates the spindle checkpoint.|complex-properties:MW = 670 kDa|figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:01575C583767DB00|rigid:BS7o+qNbuW6ll5NpcR6RJkGuQXA false myc tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P40958 uniprotkb:P26309 intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269099|imex:IM-19342-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 - - crc64:CCE7CD149C1F5ACF figure legend:1F, 2D|comment:Mad2 and Cdc20 coimmunoprecipitate from Mad3-ProteinA-depleted extracts showing that Mad2 and Cdc20 form a separate complex that does not contain Mad3.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:ADDF3FED5E7CF901|rigid:TMAeuLLYSIEy1s2XkGp4T/qzJhQ false - myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P40958 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269106|imex:IM-19342-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 - crc64:0BDFB8697935BCEB - figure legend:1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 intact-crc:7A5C793F3F5F4CD6|rigid:Uv5ThTAjTD6MXAfoxuih4SpYsuc false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40958 uniprotkb:P47074 intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269113|imex:IM-19342-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - - crc64:36550249D81BB6D1 figure legend:1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:005A90DC05F7EC63|rigid:zBlp7VL20eeUxSDkp0U1etK/j2k false - myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40958 uniprotkb:P47074 intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269120|imex:IM-19342-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - - crc64:36550249D81BB6D1 figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:954882FA49B89837|rigid:zBlp7VL20eeUxSDkp0U1etK/j2k false - tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26309 uniprotkb:P47074 intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Poddar et al. (2005) pubmed:15879521|imex:IM-19342 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269127|imex:IM-19342-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - crc64:CCE7CD149C1F5ACF crc64:36550249D81BB6D1 figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/29 2014/10/16 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:9FCA0B73E5E196F1|rigid:6YYLFVnQ6bVeNxIiGcf6DdQWF9g false - tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)