#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q58FA4 uniprotkb:Q58FA4 intact:EBI-1390691|uniprotkb:Q3U4W2|uniprotkb:Q497V7|uniprotkb:Q5PRE4|uniprotkb:Q8BQJ5|uniprotkb:Q8C3Y5|ensembl:ENSMUSP00000056778|ensembl:ENSMUSP00000112883 intact:EBI-1390691|uniprotkb:Q3U4W2|uniprotkb:Q497V7|uniprotkb:Q5PRE4|uniprotkb:Q8BQJ5|uniprotkb:Q8C3Y5|ensembl:ENSMUSP00000056778|ensembl:ENSMUSP00000112883 psi-mi:e2f8_mouse(display_long)|uniprotkb:E2f8(gene name)|psi-mi:E2f8(display_short) psi-mi:e2f8_mouse(display_long)|uniprotkb:E2f8(gene name)|psi-mi:E2f8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Maiti et al. (2005) pubmed:15722552|imex:IM-19128 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390702|imex:IM-19128-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013386.2|refseq:XP_006540616.1|refseq:XP_006540617.1|ensembl:ENSMUSG00000046179(gene)|ensembl:ENSMUST00000058745(transcript)|ensembl:ENSMUST00000119223(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WZH|reactome:R-MMU-6804116 refseq:NP_001013386.2|refseq:XP_006540616.1|refseq:XP_006540617.1|ensembl:ENSMUSG00000046179(gene)|ensembl:ENSMUST00000058745(transcript)|ensembl:ENSMUST00000119223(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WZH|reactome:R-MMU-6804116 - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/03 2014/10/16 rogid:ya3ujn3QvphtubXhzhiAoQ0syUI10090 rogid:ya3ujn3QvphtubXhzhiAoQ0syUI10090 intact-crc:621D64BB70AD5656|rigid:LmwrJTX9Via+qGkcfFtbys3JXaI false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q58FA4 uniprotkb:Q58FA4 intact:EBI-1390691|uniprotkb:Q3U4W2|uniprotkb:Q497V7|uniprotkb:Q5PRE4|uniprotkb:Q8BQJ5|uniprotkb:Q8C3Y5|ensembl:ENSMUSP00000056778|ensembl:ENSMUSP00000112883 intact:EBI-1390691|uniprotkb:Q3U4W2|uniprotkb:Q497V7|uniprotkb:Q5PRE4|uniprotkb:Q8BQJ5|uniprotkb:Q8C3Y5|ensembl:ENSMUSP00000056778|ensembl:ENSMUSP00000112883 psi-mi:e2f8_mouse(display_long)|uniprotkb:E2f8(gene name)|psi-mi:E2f8(display_short) psi-mi:e2f8_mouse(display_long)|uniprotkb:E2f8(gene name)|psi-mi:E2f8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Maiti et al. (2005) pubmed:15722552|imex:IM-19128 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390710|imex:IM-19128-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013386.2|refseq:XP_006540616.1|refseq:XP_006540617.1|ensembl:ENSMUSG00000046179(gene)|ensembl:ENSMUST00000058745(transcript)|ensembl:ENSMUST00000119223(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WZH|reactome:R-MMU-6804116 refseq:NP_001013386.2|refseq:XP_006540616.1|refseq:XP_006540617.1|ensembl:ENSMUSG00000046179(gene)|ensembl:ENSMUST00000058745(transcript)|ensembl:ENSMUST00000119223(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WZH|reactome:R-MMU-6804116 - - - figure legend:6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/03 2014/10/16 rogid:ya3ujn3QvphtubXhzhiAoQ0syUI10090 rogid:ya3ujn3QvphtubXhzhiAoQ0syUI10090 intact-crc:011CF18E9AB5FBF4|rigid:LmwrJTX9Via+qGkcfFtbys3JXaI false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q58FA4 uniprotkb:Q58FA4 intact:EBI-1390691|uniprotkb:Q3U4W2|uniprotkb:Q497V7|uniprotkb:Q5PRE4|uniprotkb:Q8BQJ5|uniprotkb:Q8C3Y5|ensembl:ENSMUSP00000056778|ensembl:ENSMUSP00000112883 intact:EBI-1390691|uniprotkb:Q3U4W2|uniprotkb:Q497V7|uniprotkb:Q5PRE4|uniprotkb:Q8BQJ5|uniprotkb:Q8C3Y5|ensembl:ENSMUSP00000056778|ensembl:ENSMUSP00000112883 psi-mi:e2f8_mouse(display_long)|uniprotkb:E2f8(gene name)|psi-mi:E2f8(display_short) psi-mi:e2f8_mouse(display_long)|uniprotkb:E2f8(gene name)|psi-mi:E2f8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Maiti et al. (2005) pubmed:15722552|imex:IM-19128 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390718|imex:IM-19128-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013386.2|refseq:XP_006540616.1|refseq:XP_006540617.1|ensembl:ENSMUSG00000046179(gene)|ensembl:ENSMUST00000058745(transcript)|ensembl:ENSMUST00000119223(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WZH|reactome:R-MMU-6804116 refseq:NP_001013386.2|refseq:XP_006540616.1|refseq:XP_006540617.1|ensembl:ENSMUSG00000046179(gene)|ensembl:ENSMUST00000058745(transcript)|ensembl:ENSMUST00000119223(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1WZH|reactome:R-MMU-6804116 - - - figure legend:6B|comment:Deletion of DNA-binding domains did not affect the interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/03 2014/10/16 rogid:ya3ujn3QvphtubXhzhiAoQ0syUI10090 rogid:ya3ujn3QvphtubXhzhiAoQ0syUI10090 intact-crc:6B224002DBEEBEB1|rigid:LmwrJTX9Via+qGkcfFtbys3JXaI false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)