#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q08722	uniprotkb:Q9P1W8	intact:EBI-1268321|uniprotkb:Q53Y71|uniprotkb:Q96A60|uniprotkb:A8K198|uniprotkb:D3DN59|ensembl:ENSP00000355361	intact:EBI-1268284|uniprotkb:Q9NQK8|uniprotkb:Q5MKL4|uniprotkb:Q8WWA5|uniprotkb:Q5D051|uniprotkb:Q5JV25|uniprotkb:B1AKP6|ensembl:ENSP00000305529	psi-mi:cd47_human(display_long)|uniprotkb:CD47(gene name)|psi-mi:CD47(display_short)|uniprotkb:MER6(gene name synonym)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Antigenic surface determinant protein OA3(gene name synonym)|uniprotkb:Protein MER6(gene name synonym)	psi-mi:sirpg_human(display_long)|uniprotkb:SIRPG(gene name)|psi-mi:SIRPG(display_short)|uniprotkb:SIRPB2(gene name synonym)|uniprotkb:Signal-regulatory protein beta-2(gene name synonym)|uniprotkb:CD172 antigen-like family member B(gene name synonym)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Piccio et al. (2005)	pubmed:15383453	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1268283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001768.1|refseq:NP_942088.1|dip:DIP-39948N|ensembl:ENSG00000196776(gene)|ensembl:ENST00000361309(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032653"(regulation of interleukin-10 production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037805|rcsb pdb:2JJS|rcsb pdb:2JJT|rcsb pdb:2VSC|rcsb pdb:4CMM|rcsb pdb:4KJY|rcsb pdb:5IWL|rcsb pdb:5TZ2|rcsb pdb:5TZT|rcsb pdb:5TZU|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-391160|reactome:R-HSA-6798695|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)	refseq:NP_001034597.1|refseq:NP_061026.2|refseq:NP_543006.2|refseq:XP_011527588.1|ensembl:ENSG00000089012(gene)|ensembl:ENST00000303415(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2JJW|rcsb pdb:4I2X|reactome:R-HSA-202733|reactome:R-HSA-391160	-	-	-	comment:Sirpg-D1D2-IgG was found to bind to T-cells expressing CD47, by flow cytometry. The binding was totally blocked by anti-CD47 mAbs, and partially inhibited by anti-Sirpg mAbs. This demonstrates that Sirpg is a receptor for CD47.|figure legend:Figure 5	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2007/06/26	2014/10/16	rogid:2hhmwvfeDFe7KHXzsBOJkjo2pjk9606	rogid:3jf/9G8F9SPikrpNKrRrd6CR4jA9606	intact-crc:3296357CB923483A|rigid:VgwJjglaaT/CUOMNDPsjheW2GrM	false	-	fusion protein:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q08722	uniprotkb:Q9P1W8	intact:EBI-1268321|uniprotkb:Q53Y71|uniprotkb:Q96A60|uniprotkb:A8K198|uniprotkb:D3DN59|ensembl:ENSP00000355361	intact:EBI-1268284|uniprotkb:Q9NQK8|uniprotkb:Q5MKL4|uniprotkb:Q8WWA5|uniprotkb:Q5D051|uniprotkb:Q5JV25|uniprotkb:B1AKP6|ensembl:ENSP00000305529	psi-mi:cd47_human(display_long)|uniprotkb:CD47(gene name)|psi-mi:CD47(display_short)|uniprotkb:MER6(gene name synonym)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Antigenic surface determinant protein OA3(gene name synonym)|uniprotkb:Protein MER6(gene name synonym)	psi-mi:sirpg_human(display_long)|uniprotkb:SIRPG(gene name)|psi-mi:SIRPG(display_short)|uniprotkb:SIRPB2(gene name synonym)|uniprotkb:Signal-regulatory protein beta-2(gene name synonym)|uniprotkb:CD172 antigen-like family member B(gene name synonym)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Piccio et al. (2005)	pubmed:15383453	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1268359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001768.1|refseq:NP_942088.1|dip:DIP-39948N|ensembl:ENSG00000196776(gene)|ensembl:ENST00000361309(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032653"(regulation of interleukin-10 production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037805|rcsb pdb:2JJS|rcsb pdb:2JJT|rcsb pdb:2VSC|rcsb pdb:4CMM|rcsb pdb:4KJY|rcsb pdb:5IWL|rcsb pdb:5TZ2|rcsb pdb:5TZT|rcsb pdb:5TZU|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-391160|reactome:R-HSA-6798695|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)	refseq:NP_001034597.1|refseq:NP_061026.2|refseq:NP_543006.2|refseq:XP_011527588.1|ensembl:ENSG00000089012(gene)|ensembl:ENST00000303415(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2JJW|rcsb pdb:4I2X|reactome:R-HSA-202733|reactome:R-HSA-391160	-	-	-	comment:Sirpg-expressing BW cells were able to conjugate with CD47-expressing Jurkat cells and this cojugation was partially blocked by anti-Sirp and anti-CD47 antibodies but not by anti-CD18 or anti-CD11a antibodies, suggesting that Sirpg-CD47 interaction significantly contributes to adhesion of T-cells to cells expressing CD47.|figure legend:Figure 6A, 6B.	taxid:9606(human-jurkat)|taxid:9606(Homo sapiens)	-	2007/06/26	2014/10/16	rogid:2hhmwvfeDFe7KHXzsBOJkjo2pjk9606	rogid:3jf/9G8F9SPikrpNKrRrd6CR4jA9606	intact-crc:0C92CC8624828729|rigid:VgwJjglaaT/CUOMNDPsjheW2GrM	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)