#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q08773 uniprotkb:Q04603 intact:EBI-31118|uniprotkb:D6W303|ensemblfungi:YOR304W intact:EBI-29938|uniprotkb:D6VSA7|ensemblfungi:YDR121W psi-mi:isw2_yeast(display_long)|uniprotkb:ISW2(gene name)|psi-mi:ISW2(display_short)|uniprotkb:Imitation switch protein 2(gene name synonym)|uniprotkb:YOR304W(locus name) psi-mi:dpb4_yeast(display_long)|uniprotkb:DPB4(gene name)|psi-mi:DPB4(display_short)|uniprotkb:DNA polymerase II subunit D(gene name synonym)|uniprotkb:YDR121W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1251884|imex:IM-19713-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014948.1|sgd:S000005831|dip:DIP-6603N|mint:Q08773|ensemblfungi:YOR304W(gene)|ensemblfungi:YOR304W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008623"(CHRAC)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044754 sgd:S000002528|refseq:NP_010406.3|dip:DIP-4621N|mint:Q04603|ensemblfungi:YDR121W(gene)|ensemblfungi:YDR121W_mRNA(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 - crc64:F71007D7B25C9348 - figure legend:1A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:Lo2JIjBvjy0D1IW6svZGFvEqHrA559292 rogid:vEA21+6hLP2O4eSSuKA49lbi0E0559292 intact-crc:AF183F39A96AA798|rigid:IJpkwHKTb8jp3KLqa8RjGRUPuMc false flag tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q08773 uniprotkb:P40366 intact:EBI-31118|uniprotkb:D6W303|ensemblfungi:YOR304W intact:EBI-25910|uniprotkb:D6VWB7|ensemblfungi:YJL065C psi-mi:isw2_yeast(display_long)|uniprotkb:ISW2(gene name)|psi-mi:ISW2(display_short)|uniprotkb:Imitation switch protein 2(gene name synonym)|uniprotkb:YOR304W(locus name) psi-mi:dls1_yeast(display_long)|uniprotkb:YJL065C(locus name)|uniprotkb:J1115(orf name)|uniprotkb:HRD167(orf name)|uniprotkb:DPB3-like subunit of ISW2 complex 1(gene name synonym)|uniprotkb:DLS1(gene name)|psi-mi:DLS1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1251884|imex:IM-19713-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014948.1|sgd:S000005831|dip:DIP-6603N|mint:Q08773|ensemblfungi:YOR304W(gene)|ensemblfungi:YOR304W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008623"(CHRAC)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044754 refseq:NP_012470.1|sgd:S000003601|mint:P40366|dip:DIP-1788N|ensemblfungi:YJL065C(gene)|ensemblfungi:YJL065C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 - crc64:F71007D7B25C9348 - figure legend:1A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:Lo2JIjBvjy0D1IW6svZGFvEqHrA559292 rogid:qEdLdC7hAsf9uSbO/S3hX/BpGCU559292 intact-crc:AF183F39A96AA798|rigid:IJpkwHKTb8jp3KLqa8RjGRUPuMc false flag tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P40366 uniprotkb:P53125 intact:EBI-25910|uniprotkb:D6VWB7|ensemblfungi:YJL065C intact:EBI-23967|uniprotkb:D6VU16|ensemblfungi:YGL133W psi-mi:dls1_yeast(display_long)|uniprotkb:YJL065C(locus name)|uniprotkb:J1115(orf name)|uniprotkb:HRD167(orf name)|uniprotkb:DPB3-like subunit of ISW2 complex 1(gene name synonym)|uniprotkb:DLS1(gene name)|psi-mi:DLS1(display_short) psi-mi:itc1_yeast(display_long)|uniprotkb:G2842(orf name)|uniprotkb:YGL133W(locus name)|uniprotkb:ITC1(gene name)|psi-mi:ITC1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1251892|imex:IM-19713-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012470.1|sgd:S000003601|mint:P40366|dip:DIP-1788N|ensemblfungi:YJL065C(gene)|ensemblfungi:YJL065C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 refseq:NP_011382.1|sgd:S000003101|dip:DIP-6737N|mint:P53125|ensemblfungi:YGL133W(gene)|ensemblfungi:YGL133W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR028941 go:"GO:0008623"(CHRAC) - - figure legend:1B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:qEdLdC7hAsf9uSbO/S3hX/BpGCU559292 rogid:srVskYPFnFM0y+W0zkCLwKQ43jU559292 intact-crc:55915926BEAADCD0|rigid:m0kXw0aq7xCpwavUhiwXCRG/VcA false flag tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P40366 uniprotkb:Q08773 intact:EBI-25910|uniprotkb:D6VWB7|ensemblfungi:YJL065C intact:EBI-31118|uniprotkb:D6W303|ensemblfungi:YOR304W psi-mi:dls1_yeast(display_long)|uniprotkb:YJL065C(locus name)|uniprotkb:J1115(orf name)|uniprotkb:HRD167(orf name)|uniprotkb:DPB3-like subunit of ISW2 complex 1(gene name synonym)|uniprotkb:DLS1(gene name)|psi-mi:DLS1(display_short) psi-mi:isw2_yeast(display_long)|uniprotkb:ISW2(gene name)|psi-mi:ISW2(display_short)|uniprotkb:Imitation switch protein 2(gene name synonym)|uniprotkb:YOR304W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1251892|imex:IM-19713-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012470.1|sgd:S000003601|mint:P40366|dip:DIP-1788N|ensemblfungi:YJL065C(gene)|ensemblfungi:YJL065C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 refseq:NP_014948.1|sgd:S000005831|dip:DIP-6603N|mint:Q08773|ensemblfungi:YOR304W(gene)|ensemblfungi:YOR304W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008623"(CHRAC)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044754 go:"GO:0008623"(CHRAC) - crc64:F71007D7B25C9348 figure legend:1B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:qEdLdC7hAsf9uSbO/S3hX/BpGCU559292 rogid:Lo2JIjBvjy0D1IW6svZGFvEqHrA559292 intact-crc:55915926BEAADCD0|rigid:m0kXw0aq7xCpwavUhiwXCRG/VcA false flag tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P40366 uniprotkb:Q04603 intact:EBI-25910|uniprotkb:D6VWB7|ensemblfungi:YJL065C intact:EBI-29938|uniprotkb:D6VSA7|ensemblfungi:YDR121W psi-mi:dls1_yeast(display_long)|uniprotkb:YJL065C(locus name)|uniprotkb:J1115(orf name)|uniprotkb:HRD167(orf name)|uniprotkb:DPB3-like subunit of ISW2 complex 1(gene name synonym)|uniprotkb:DLS1(gene name)|psi-mi:DLS1(display_short) psi-mi:dpb4_yeast(display_long)|uniprotkb:DPB4(gene name)|psi-mi:DPB4(display_short)|uniprotkb:DNA polymerase II subunit D(gene name synonym)|uniprotkb:YDR121W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1251892|imex:IM-19713-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012470.1|sgd:S000003601|mint:P40366|dip:DIP-1788N|ensemblfungi:YJL065C(gene)|ensemblfungi:YJL065C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 sgd:S000002528|refseq:NP_010406.3|dip:DIP-4621N|mint:Q04603|ensemblfungi:YDR121W(gene)|ensemblfungi:YDR121W_mRNA(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 go:"GO:0008623"(CHRAC) - - figure legend:1B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:qEdLdC7hAsf9uSbO/S3hX/BpGCU559292 rogid:vEA21+6hLP2O4eSSuKA49lbi0E0559292 intact-crc:55915926BEAADCD0|rigid:m0kXw0aq7xCpwavUhiwXCRG/VcA false flag tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q04603 uniprotkb:Q08773 intact:EBI-29938|uniprotkb:D6VSA7|ensemblfungi:YDR121W intact:EBI-31118|uniprotkb:D6W303|ensemblfungi:YOR304W psi-mi:dpb4_yeast(display_long)|uniprotkb:DPB4(gene name)|psi-mi:DPB4(display_short)|uniprotkb:DNA polymerase II subunit D(gene name synonym)|uniprotkb:YDR121W(locus name) psi-mi:isw2_yeast(display_long)|uniprotkb:ISW2(gene name)|psi-mi:ISW2(display_short)|uniprotkb:Imitation switch protein 2(gene name synonym)|uniprotkb:YOR304W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1251950|imex:IM-19713-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002528|refseq:NP_010406.3|dip:DIP-4621N|mint:Q04603|ensemblfungi:YDR121W(gene)|ensemblfungi:YDR121W_mRNA(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 refseq:NP_014948.1|sgd:S000005831|dip:DIP-6603N|mint:Q08773|ensemblfungi:YOR304W(gene)|ensemblfungi:YOR304W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008623"(CHRAC)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044754 - - crc64:F71007D7B25C9348 comment:Immunodepletion studies suggested both prey proteins bound to DPB4|figure legend:Fig. 2A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:vEA21+6hLP2O4eSSuKA49lbi0E0559292 rogid:Lo2JIjBvjy0D1IW6svZGFvEqHrA559292 intact-crc:434A46442129D7AA|rigid:AtJXNUhtKWsOJYWmIELwcZOLrbc false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04603 uniprotkb:P21951 intact:EBI-29938|uniprotkb:D6VSA7|ensemblfungi:YDR121W intact:EBI-6140|uniprotkb:D6W0T1|ensemblfungi:YNL262W psi-mi:dpb4_yeast(display_long)|uniprotkb:DPB4(gene name)|psi-mi:DPB4(display_short)|uniprotkb:DNA polymerase II subunit D(gene name synonym)|uniprotkb:YDR121W(locus name) psi-mi:dpoe_yeast(display_long)|uniprotkb:POL2(gene name)|psi-mi:POL2(display_short)|uniprotkb:DUN2(gene name synonym)|uniprotkb:YNL262W(locus name)|uniprotkb:N0825(orf name)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1251950|imex:IM-19713-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002528|refseq:NP_010406.3|dip:DIP-4621N|mint:Q04603|ensemblfungi:YDR121W(gene)|ensemblfungi:YDR121W_mRNA(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 refseq:NP_014137.1|sgd:S000005206|dip:DIP-2532N|mint:P21951|ensemblfungi:YNL262W(gene)|ensemblfungi:YNL262W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032183"(SUMO binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035822"(gene conversion)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:4M8O|rcsb pdb:4PTF|rcsb pdb:5OKI|rcsb pdb:6FWK|rcsb pdb:6G0A|rcsb pdb:6H1V|rcsb pdb:6HV8|rcsb pdb:6HV9|rcsb pdb:6I8A|rcsb pdb:6QIB|rcsb pdb:6S1C|rcsb pdb:6S2E|rcsb pdb:6S2F|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 - - crc64:CBCDDE2AB147D65B comment:Immunodepletion studies suggested both prey proteins bound to DPB4|figure legend:Fig. 2A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:vEA21+6hLP2O4eSSuKA49lbi0E0559292 rogid:2OXq7Xt5TAcYf7QLOpKzpol96sE559292 intact-crc:434A46442129D7AA|rigid:AtJXNUhtKWsOJYWmIELwcZOLrbc false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40366 uniprotkb:P53125 intact:EBI-25910|uniprotkb:D6VWB7|ensemblfungi:YJL065C intact:EBI-23967|uniprotkb:D6VU16|ensemblfungi:YGL133W psi-mi:dls1_yeast(display_long)|uniprotkb:YJL065C(locus name)|uniprotkb:J1115(orf name)|uniprotkb:HRD167(orf name)|uniprotkb:DPB3-like subunit of ISW2 complex 1(gene name synonym)|uniprotkb:DLS1(gene name)|psi-mi:DLS1(display_short) psi-mi:itc1_yeast(display_long)|uniprotkb:G2842(orf name)|uniprotkb:YGL133W(locus name)|uniprotkb:ITC1(gene name)|psi-mi:ITC1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1252004|imex:IM-19713-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012470.1|sgd:S000003601|mint:P40366|dip:DIP-1788N|ensemblfungi:YJL065C(gene)|ensemblfungi:YJL065C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 refseq:NP_011382.1|sgd:S000003101|dip:DIP-6737N|mint:P53125|ensemblfungi:YGL133W(gene)|ensemblfungi:YGL133W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018501|interpro:IPR028941 - - - comment:Immunodepletion of Dls1 resulted in a partial depletion of both Isw2 and Itc1, suggesting the presence of Isw2 and Itc1 populations that do not stably interact with Dls1.|figure legend:Fig. 2C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:qEdLdC7hAsf9uSbO/S3hX/BpGCU559292 rogid:srVskYPFnFM0y+W0zkCLwKQ43jU559292 intact-crc:AD2BC88F36F2673F|rigid:vQOMv+PBzyB3jOgMgviNhCc+iUA false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40366 uniprotkb:Q08773 intact:EBI-25910|uniprotkb:D6VWB7|ensemblfungi:YJL065C intact:EBI-31118|uniprotkb:D6W303|ensemblfungi:YOR304W psi-mi:dls1_yeast(display_long)|uniprotkb:YJL065C(locus name)|uniprotkb:J1115(orf name)|uniprotkb:HRD167(orf name)|uniprotkb:DPB3-like subunit of ISW2 complex 1(gene name synonym)|uniprotkb:DLS1(gene name)|psi-mi:DLS1(display_short) psi-mi:isw2_yeast(display_long)|uniprotkb:ISW2(gene name)|psi-mi:ISW2(display_short)|uniprotkb:Imitation switch protein 2(gene name synonym)|uniprotkb:YOR304W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) McConnell et al. (2004) pubmed:15024052|imex:IM-19713 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1252004|imex:IM-19713-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012470.1|sgd:S000003601|mint:P40366|dip:DIP-1788N|ensemblfungi:YJL065C(gene)|ensemblfungi:YJL065C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0008623"(CHRAC)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962 refseq:NP_014948.1|sgd:S000005831|dip:DIP-6603N|mint:Q08773|ensemblfungi:YOR304W(gene)|ensemblfungi:YOR304W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008623"(CHRAC)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044754 - - crc64:F71007D7B25C9348 comment:Immunodepletion of Dls1 resulted in a partial depletion of both Isw2 and Itc1, suggesting the presence of Isw2 and Itc1 populations that do not stably interact with Dls1.|figure legend:Fig. 2C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/14 2014/10/16 rogid:qEdLdC7hAsf9uSbO/S3hX/BpGCU559292 rogid:Lo2JIjBvjy0D1IW6svZGFvEqHrA559292 intact-crc:AD2BC88F36F2673F|rigid:vQOMv+PBzyB3jOgMgviNhCc+iUA false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)