#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P36630 uniprotkb:P87060 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1185389|uniprotkb:Q9P7P3|ensemblfungi:"SPBC1718.01.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:pop1_schpo(display_long)|uniprotkb:WD repeat-containing protein ste16(gene name synonym)|uniprotkb:pop1(gene name)|psi-mi:pop1(display_short)|uniprotkb:SPBC1718.01(orf name)|uniprotkb:SPBC2G2.18(orf name)|uniprotkb:ste16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yamano et al. (2004) pubmed:14970237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1212654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:XP_001713146.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|ensemblfungi:SPBC1718.01(gene)|ensemblfungi:SPBC1718.01.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR036047|interpro:IPR036322 - - - figure legend:Figure 3A and 3B.|comment:Pop1 was able to interact with Cig2 in-vivo and this reaction was specific and able to take place even without the presence of Pop1's partner Pop2 in Pop2 depleted cells. taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/03/08 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:fpsox2UXaKWswVhuSnBBtqkY1/g284812 intact-crc:F4E7A1FEF7B58AAF|rigid:Y1uPGT2e8AExoyR7ptegTlU4rlU false - ha tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36630 uniprotkb:P87060 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1185389|uniprotkb:Q9P7P3|ensemblfungi:"SPBC1718.01.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:pop1_schpo(display_long)|uniprotkb:WD repeat-containing protein ste16(gene name synonym)|uniprotkb:pop1(gene name)|psi-mi:pop1(display_short)|uniprotkb:SPBC1718.01(orf name)|uniprotkb:SPBC2G2.18(orf name)|uniprotkb:ste16(gene name synonym) psi-mi:"MI:0096"(pull down) Yamano et al. (2004) pubmed:14970237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1212728 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:XP_001713146.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|ensemblfungi:SPBC1718.01(gene)|ensemblfungi:SPBC1718.01.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR036047|interpro:IPR036322 - - - figure legend:Figure 4A.|comment:"Pop1 was able to interact with Cig2 in-vitro. Mutation of the destruction box (AA 51-59)of cig2 (R51A, L54A) did not interfere with this interaction." taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/08 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:fpsox2UXaKWswVhuSnBBtqkY1/g284812 intact-crc:62E8833CBE3B5C7A|rigid:Y1uPGT2e8AExoyR7ptegTlU4rlU false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41411 uniprotkb:P87060 intact:EBI-1207853|ensemblfungi:"SPBC14C8.07c.1:pep" intact:EBI-1185389|uniprotkb:Q9P7P3|ensemblfungi:"SPBC1718.01.1:pep" psi-mi:cdc18_schpo(display_long)|uniprotkb:cdc18(gene name)|psi-mi:cdc18(display_short)|uniprotkb:SPBC14C8.07c(orf name) psi-mi:pop1_schpo(display_long)|uniprotkb:WD repeat-containing protein ste16(gene name synonym)|uniprotkb:pop1(gene name)|psi-mi:pop1(display_short)|uniprotkb:SPBC1718.01(orf name)|uniprotkb:SPBC2G2.18(orf name)|uniprotkb:ste16(gene name synonym) psi-mi:"MI:0096"(pull down) Yamano et al. (2004) pubmed:14970237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1212800 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_595910.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|reactome:R-SPO-68689|reactome:R-SPO-68962|reactome:R-SPO-69017|interpro:IPR027417|reactome:R-SPO-176187|ensemblfungi:SPBC14C8.07c(gene)|ensemblfungi:SPBC14C8.07c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0051301"(cell division)|go:"GO:0140530"(MCM complex loading)|go:"GO:1902985"(mitotic pre-replicative complex assembly)|go:"GO:1903468"(positive regulation of DNA replication initiation)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR036388|interpro:IPR036390|reactome:R-SPO-68949|interpro:IPR041083|reactome:R-SPO-68827|reactome:R-SPO-68867 refseq:XP_001713146.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|ensemblfungi:SPBC1718.01(gene)|ensemblfungi:SPBC1718.01.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR036047|interpro:IPR036322 - - - figure legend:Figure 4A, 5A, 5B.|comment:Pop1 was able to interact with Cdc18 in-vitro. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/08 2014/10/16 rogid:jB9IGO2TuHbrQngQUhh0PiIudgg284812 rogid:fpsox2UXaKWswVhuSnBBtqkY1/g284812 intact-crc:4D8D41488DE908AF|rigid:x7sIzaRRoZoPoDlC8AwWrFhU1L8 false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40380 uniprotkb:P87060 intact:EBI-1187892|uniprotkb:O74373|ensemblfungi:"SPBC32F12.09.1:pep" intact:EBI-1185389|uniprotkb:Q9P7P3|ensemblfungi:"SPBC1718.01.1:pep" psi-mi:rum1_schpo(display_long)|uniprotkb:rum1(gene name)|psi-mi:rum1(display_short)|uniprotkb:SPBC32F12.09(orf name)|uniprotkb:p25-rum1(gene name synonym) psi-mi:pop1_schpo(display_long)|uniprotkb:WD repeat-containing protein ste16(gene name synonym)|uniprotkb:pop1(gene name)|psi-mi:pop1(display_short)|uniprotkb:SPBC1718.01(orf name)|uniprotkb:SPBC2G2.18(orf name)|uniprotkb:ste16(gene name synonym) psi-mi:"MI:0096"(pull down) Yamano et al. (2004) pubmed:14970237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1212821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596152.1|ensemblfungi:SPBC32F12.09(gene)|ensemblfungi:SPBC32F12.09.1(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle) refseq:XP_001713146.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|ensemblfungi:SPBC1718.01(gene)|ensemblfungi:SPBC1718.01.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR036047|interpro:IPR036322 - - - figure legend:Figure 4A, 5A, 5B.|comment:Pop1 was able to interact with Rum1 in-vitro. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/08 2014/10/16 rogid:66UWvndQ1xihZmi/pEZbhdSJsxg284812 rogid:fpsox2UXaKWswVhuSnBBtqkY1/g284812 intact-crc:5F889EDAA5DDA353|rigid:kCPxjR2AKHrFzA4rkpyjbYwXHnM false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36630 uniprotkb:P87060 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1185389|uniprotkb:Q9P7P3|ensemblfungi:"SPBC1718.01.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:pop1_schpo(display_long)|uniprotkb:WD repeat-containing protein ste16(gene name synonym)|uniprotkb:pop1(gene name)|psi-mi:pop1(display_short)|uniprotkb:SPBC1718.01(orf name)|uniprotkb:SPBC2G2.18(orf name)|uniprotkb:ste16(gene name synonym) psi-mi:"MI:0096"(pull down) Yamano et al. (2004) pubmed:14970237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1212877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:XP_001713146.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|ensemblfungi:SPBC1718.01(gene)|ensemblfungi:SPBC1718.01.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR036047|interpro:IPR036322 - - - figure legend:Figure 4B.|comment:It was observed that cig2 phosphorylation was a requirement for binding to pop1. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/08 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:fpsox2UXaKWswVhuSnBBtqkY1/g284812 intact-crc:E4A564C210F7ECBC|rigid:Y1uPGT2e8AExoyR7ptegTlU4rlU false 35s radiolabel:?-?|phosphorylated residue:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36630 uniprotkb:P87060 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1185389|uniprotkb:Q9P7P3|ensemblfungi:"SPBC1718.01.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:pop1_schpo(display_long)|uniprotkb:WD repeat-containing protein ste16(gene name synonym)|uniprotkb:pop1(gene name)|psi-mi:pop1(display_short)|uniprotkb:SPBC1718.01(orf name)|uniprotkb:SPBC2G2.18(orf name)|uniprotkb:ste16(gene name synonym) psi-mi:"MI:0096"(pull down) Yamano et al. (2004) pubmed:14970237 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1212891 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:XP_001713146.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|ensemblfungi:SPBC1718.01(gene)|ensemblfungi:SPBC1718.01.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR036047|interpro:IPR036322 - - - figure legend:Figure 5A, 5B, 5C.|comment:"It was discovered from deletion analysis, that an internal 93 amino acid region of Cig2 (AA 181-273) was necessary and sufficient for binding to Pop1." taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/08 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:fpsox2UXaKWswVhuSnBBtqkY1/g284812 intact-crc:8C0F8C86BD40AEE4|rigid:Y1uPGT2e8AExoyR7ptegTlU4rlU false 35s radiolabel:?-?|necessary binding region:181-273 glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)