#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9EPK5 uniprotkb:P23441 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Park et al. (2004) pubmed:14970209 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1224184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity) rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development) - - - figure legend:4B taxid:10090(mouse-mle15)|taxid:10090(Mouse SV40 large T antigen immortalized mouse lung epithelial cells) - 2007/03/29 2014/10/16 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116 intact-crc:7C2170CB8953CF14|rigid:drBc9Bb3StOG+LxBiOteOoxPmAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EPK5 uniprotkb:P23441 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2004) pubmed:14970209 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1224195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity) rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development) - - - figure legend:5A taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/29 2014/10/16 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116 intact-crc:849FCE461500D10D|rigid:drBc9Bb3StOG+LxBiOteOoxPmAk false glutathione s tranferase tag:?-? sufficient binding region:1-221 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P23441 uniprotkb:Q9EPK5 intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym) psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2004) pubmed:14970209 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1224209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity) - - - figure legend:5A taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/29 2014/10/16 rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 intact-crc:49A0D500089B5B19|rigid:drBc9Bb3StOG+LxBiOteOoxPmAk false necessary binding region:1-158|flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)