#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8R478 uniprotkb:P51974 intact:EBI-1223229 intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966 psi-mi:wbp2_rat(display_long)|uniprotkb:Wbp2(gene name)|psi-mi:Wbp2(display_short) psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym) psi-mi:"MI:0084"(phage display) Nitsch et al. (2004) pubmed:14531730|mint:MINT-5216749 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1223225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004182(GRAM)|rgd:620032|refseq:NP_620431.1|interpro:IPR033598|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR044852 rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565 - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/28 2014/10/16 rogid:+Th10Do760XTMhOxkHFUsPxfFfs10116 rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116 intact-crc:CAF166723B27F247|rigid:FojfNU1tpCjq1J+9AzyzyEr5v3E false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51974 uniprotkb:Q8R478 intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966 intact:EBI-1223229 psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym) psi-mi:wbp2_rat(display_long)|uniprotkb:Wbp2(gene name)|psi-mi:Wbp2(display_short) psi-mi:"MI:0663"(confocal microscopy) Nitsch et al. (2004) pubmed:14531730|mint:MINT-5216749 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1223294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565 interpro:IPR004182(GRAM)|rgd:620032|refseq:NP_620431.1|interpro:IPR033598|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR044852 go:"GO:0005634"(nucleus) - - figure legend:4 taxid:10116(rat-pc-cl3)|taxid:10116(Rat thyroid epithelial cells) - 2007/03/28 2014/10/16 rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116 rogid:+Th10Do760XTMhOxkHFUsPxfFfs10116 intact-crc:D39BB1915D18043E|rigid:FojfNU1tpCjq1J+9AzyzyEr5v3E false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8R478 uniprotkb:P51974 intact:EBI-1223229 intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966 psi-mi:wbp2_rat(display_long)|uniprotkb:Wbp2(gene name)|psi-mi:Wbp2(display_short) psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym) psi-mi:"MI:0096"(pull down) Nitsch et al. (2004) pubmed:14531730|mint:MINT-5216749 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1223244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004182(GRAM)|rgd:620032|refseq:NP_620431.1|interpro:IPR033598|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR044852 rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565 - - - figure legend:5A taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/28 2014/10/16 rogid:+Th10Do760XTMhOxkHFUsPxfFfs10116 rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116 intact-crc:B5095A557E67082F|rigid:FojfNU1tpCjq1J+9AzyzyEr5v3E false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8R478 uniprotkb:P51974 intact:EBI-1223229 intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966 psi-mi:wbp2_rat(display_long)|uniprotkb:Wbp2(gene name)|psi-mi:Wbp2(display_short) psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym) psi-mi:"MI:0096"(pull down) Nitsch et al. (2004) pubmed:14531730|mint:MINT-5216749 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1224095 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004182(GRAM)|rgd:620032|refseq:NP_620431.1|interpro:IPR033598|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071442"(positive regulation of histone H3-K14 acetylation)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR044852 rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565 - - - figure legend:5B taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/03/28 2014/10/16 rogid:+Th10Do760XTMhOxkHFUsPxfFfs10116 rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116 intact-crc:B487E248D303B4E3|rigid:FojfNU1tpCjq1J+9AzyzyEr5v3E false flag tag:?-? necessary binding region:1-349 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)