#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q09763 uniprotkb:Q01112 intact:EBI-1556299|ensemblfungi:"SPAC24H6.09.1:pep" intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep" psi-mi:gef1_schpo(display_long)|uniprotkb:gef1(gene name)|psi-mi:gef1(display_short)|uniprotkb:SPAC24H6.09(orf name) psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name) psi-mi:"MI:0018"(two hybrid) Hirota et al. (2003) pubmed:12972551|imex:IM-19231 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1559052|imex:IM-19231-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_592943.1|interpro:IPR000219("Dbl homology (DH) domain")|mint:Q09763|interpro:IPR035899|ensemblfungi:SPAC24H6.09(gene)|ensemblfungi:SPAC24H6.09.1(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031097"(medial cortex)|go:"GO:0032153"(cell division site)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051519"(activation of bipolar cell growth)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0061645"(endocytic patch)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903473"(positive regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:2000100"(regulation of establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|reactome:R-SPO-416482|reactome:R-SPO-9013148 refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis) - - - figure legend:Fig 2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/27 2014/10/16 rogid:CpdwHygxxHnDPwbQLsOHyp+HDvs284812 rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812 intact-crc:5CE070126BF745C7|rigid:hTuH6O9ThHu/j9DyEf5QoOR6Q5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q09763 uniprotkb:Q01112 intact:EBI-1556299|ensemblfungi:"SPAC24H6.09.1:pep" intact:EBI-767502|ensemblfungi:"SPAC110.03.1:pep" psi-mi:gef1_schpo(display_long)|uniprotkb:gef1(gene name)|psi-mi:gef1(display_short)|uniprotkb:SPAC24H6.09(orf name) psi-mi:cdc42_schpo(display_long)|uniprotkb:CDC42Sp(gene name synonym)|uniprotkb:cdc42(gene name)|psi-mi:cdc42(display_short)|uniprotkb:SPAC110.03(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirota et al. (2003) pubmed:12972551|imex:IM-19231 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1559062|imex:IM-19231-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_592943.1|interpro:IPR000219("Dbl homology (DH) domain")|mint:Q09763|interpro:IPR035899|ensemblfungi:SPAC24H6.09(gene)|ensemblfungi:SPAC24H6.09.1(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031097"(medial cortex)|go:"GO:0032153"(cell division site)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051519"(activation of bipolar cell growth)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0061645"(endocytic patch)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1903473"(positive regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:2000100"(regulation of establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|reactome:R-SPO-416482|reactome:R-SPO-9013148 refseq:NP_593536.1|dip:DIP-275N|mint:Q01112|ensemblfungi:SPAC110.03(gene)|ensemblfungi:SPAC110.03.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032951"(regulation of beta-glucan biosynthetic process)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:2000769"(regulation of establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|reactome:R-SPO-2029482|reactome:R-SPO-389359|reactome:R-SPO-5626467|reactome:R-SPO-5627123|reactome:R-SPO-5687128|reactome:R-SPO-9013148|reactome:R-SPO-9013406|reactome:R-SPO-9013409|go:"GO:0006897"(endocytosis) - - - figure legend:Fig 2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/11/27 2014/10/16 rogid:CpdwHygxxHnDPwbQLsOHyp+HDvs284812 rogid:Hm+T2A2V+AZYh2VtuqATJiUDgUI284812 intact-crc:382728B03CDFC5EC|rigid:hTuH6O9ThHu/j9DyEf5QoOR6Q5s false flag tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)