#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51974	uniprotkb:P23441	intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966	intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121	psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym)	psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Di et al. (2003)	pubmed:12441357	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565	rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development)	go:"GO:0005634"(nucleus)	-	-	figure legend:1|comment:Proteins colocalized in numerous interconnected nucleoplasmic domains but neither were present in the nucleoli.	taxid:10116(rat-pc-cl3)|taxid:10116(Rat thyroid epithelial cells)	-	2007/03/28	2014/10/16	rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116	rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116	intact-crc:AB14F9C10A1BBF49|rigid:lBTTUOsQ6dbUTlUi9LMt0OD90uo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P51974	uniprotkb:P23441	intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966	intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121	psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym)	psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Di et al. (2003)	pubmed:12441357	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565	rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development)	-	-	-	figure legend:2C	taxid:10116(rat-pc-cl3)|taxid:10116(Rat thyroid epithelial cells)	-	2007/03/28	2014/10/16	rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116	rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116	intact-crc:39CF029EF8AF96FD|rigid:lBTTUOsQ6dbUTlUi9LMt0OD90uo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P51974	uniprotkb:P23441	intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966	intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121	psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym)	psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Di et al. (2003)	pubmed:12441357	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565	rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development)	-	-	-	figure legend:2B	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/28	2014/10/16	rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116	rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116	intact-crc:1D828291D11F3528|rigid:lBTTUOsQ6dbUTlUi9LMt0OD90uo	false	glutathione s tranferase tag:?-?	his tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23441	uniprotkb:P51974	intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121	intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966	psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)	psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Di et al. (2003)	pubmed:12441357	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development)	rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565	-	-	-	figure legend:2A	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/28	2014/10/16	rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116	rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116	intact-crc:8A8E2176286A09A2|rigid:lBTTUOsQ6dbUTlUi9LMt0OD90uo	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23441	uniprotkb:P51974	intact:EBI-1223127|uniprotkb:O08630|uniprotkb:O70121	intact:EBI-1223113|uniprotkb:Q66HM8|ensembl:ENSRNOP00000033966	psi-mi:nkx21_rat(display_long)|uniprotkb:Nkx2-1(gene name)|psi-mi:Nkx2-1(display_short)|uniprotkb:Nkx-2.1(gene name synonym)|uniprotkb:Ttf1(gene name synonym)|uniprotkb:Ttf-1(gene name synonym)|uniprotkb:Titf1(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)	psi-mi:pax8_rat(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Di et al. (2003)	pubmed:12441357	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3866|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR020479|interpro:IPR009057(Homeodomain-like)|rcsb pdb:1FTT|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002016"(regulation of blood volume by renin-angiotensin)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007389"(pattern specification process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:1990401"(embryonic lung development)	rgd:620434|refseq:NP_112403.2|ensembl:ENSRNOG00000026203(gene)|ensembl:ENSRNOT00000031058(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565	-	-	-	figure legend:2A and 5|caution:The deletion construct is referenced in the text	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/28	2014/10/16	rogid:alGJDmyo1FYfFA7vK9p7KQlLSxk10116	rogid:RQGpNvOCuEI/8O5Nd0asiewEjLI10116	intact-crc:52D97B3922EFAAE2|rigid:lBTTUOsQ6dbUTlUi9LMt0OD90uo	false	sufficient binding region:1-221	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)