#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P09936	uniprotkb:Q92905	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1181897	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664	omim:608935(primary-reference)	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/01/05	2014/10/16	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	intact-crc:5FF84867D8A6AF77|rigid:apXvqDXA2q+HB8bXpVVw7aaqmaM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P09936	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:"MI:0018"(two hybrid)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1181901	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	omim:608935(primary-reference)	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/01/05	2014/10/16	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	intact-crc:DE20A1A79B67BE2E|rigid:OXLbOzUmSBIyETJ+uzYiKmjWfrg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09936	uniprotkb:Q96S59	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1181906	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1	omim:608935(primary-reference)	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/01/05	2014/10/16	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606	intact-crc:52622F9460FDB869|rigid:S8vlj6lbN1e6v279s2UfWfljsA8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09936	uniprotkb:Q92905	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1181968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664	omim:608935(primary-reference)	-	-	figure legend:1 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2007/01/05	2014/10/16	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	intact-crc:5F9F1963F6B5352E|rigid:apXvqDXA2q+HB8bXpVVw7aaqmaM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92905	uniprotkb:P46527	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	intact:EBI-519280|uniprotkb:Q16307|uniprotkb:Q9BUS6|ensembl:ENSP00000228872|ensembl:ENSP00000507272|uniprotkb:Q5U0H2	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:cdn1b_human(display_long)|uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym)|uniprotkb:p27Kip1(gene name synonym)|uniprotkb:CDKN1B(gene name)|psi-mi:CDKN1B(display_short)|uniprotkb:KIP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1182075	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664	refseq:NP_004055.1|rcsb pdb:1JSU|rcsb pdb:2AST|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6P8E|rcsb pdb:6P8F|rcsb pdb:6P8G|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5625900|reactome:R-HSA-5674400|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-9607240|reactome:R-HSA-9617828|reactome:R-HSA-9634638|reactome:R-HSA-9661069|ensembl:ENSG00000111276(gene)|ensembl:ENST00000228872(transcript)|ensembl:ENST00000614874(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001890"(placenta development)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048839"(inner ear development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090398"(cellular senescence)|go:"GO:1902746"(regulation of lens fiber cell differentiation)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029843|mint:P46527|rcsb pdb:1H27|dip:DIP-33341N	omim:608935(primary-reference)	-	-	figure legend:3 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2007/01/05	2014/10/16	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	rogid:UGcAvE0fJ9JmjMbh0s4ILpSzV+49606	intact-crc:9A24A1870BDBA2E5|rigid:wQQSafvy80WrzWaV/NbkpGqfL1E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46527	uniprotkb:P09936	intact:EBI-519280|uniprotkb:Q16307|uniprotkb:Q9BUS6|ensembl:ENSP00000228872|ensembl:ENSP00000507272|uniprotkb:Q5U0H2	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	psi-mi:cdn1b_human(display_long)|uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym)|uniprotkb:p27Kip1(gene name synonym)|uniprotkb:CDKN1B(gene name)|psi-mi:CDKN1B(display_short)|uniprotkb:KIP1(gene name synonym)	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1182097	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004055.1|rcsb pdb:1JSU|rcsb pdb:2AST|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6P8E|rcsb pdb:6P8F|rcsb pdb:6P8G|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5625900|reactome:R-HSA-5674400|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-9607240|reactome:R-HSA-9617828|reactome:R-HSA-9634638|reactome:R-HSA-9661069|ensembl:ENSG00000111276(gene)|ensembl:ENST00000228872(transcript)|ensembl:ENST00000614874(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001890"(placenta development)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048839"(inner ear development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090398"(cellular senescence)|go:"GO:1902746"(regulation of lens fiber cell differentiation)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029843|mint:P46527|rcsb pdb:1H27|dip:DIP-33341N	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	omim:608935(primary-reference)	-	-	figure legend:3 C|comment:The antibody used, K25020, mainly recognizes the nuclear form of p27. The M197 antibody which recognizes mainly the cytoplasmic form of p27 did not coimmunoprecipitate PGP9.5.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2007/01/05	2014/10/16	rogid:UGcAvE0fJ9JmjMbh0s4ILpSzV+49606	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	intact-crc:E44CAE7641EF9446|rigid:pNC4nBA2rKDOcdqPZWKdC2I+LlA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09936	uniprotkb:Q92905	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1181993	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664	omim:608935(primary-reference)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)	-	-	figure legend:1 B|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2007/01/05	2014/10/16	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	intact-crc:28A2277D3F290ECF|rigid:apXvqDXA2q+HB8bXpVVw7aaqmaM	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q92905	uniprotkb:P22087	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1182007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664	refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N	omim:608935(primary-reference)|go:"GO:0005730"(nucleolus)	-	-	figure legend:2|comment:Fibrillarin is only present in the nucleolus in interphase cells.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2007/01/05	2014/10/16	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606	intact-crc:C9713766E08DB800|rigid:dUc0ahPwrE7Ag1yq004/0yLKhio	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q92905	uniprotkb:P46527	intact:EBI-594661|uniprotkb:O15386|uniprotkb:Q6AW95|uniprotkb:Q86WQ4|uniprotkb:Q9BQ17|ensembl:ENSP00000350512	intact:EBI-519280|uniprotkb:Q16307|uniprotkb:Q9BUS6|ensembl:ENSP00000228872|ensembl:ENSP00000507272|uniprotkb:Q5U0H2	psi-mi:csn5_human(display_long)|uniprotkb:Jun activation domain-binding protein 1(gene name synonym)|uniprotkb:COPS5(gene name)|psi-mi:COPS5(display_short)|uniprotkb:CSN5(gene name synonym)|uniprotkb:JAB1(gene name synonym)	psi-mi:cdn1b_human(display_long)|uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym)|uniprotkb:p27Kip1(gene name synonym)|uniprotkb:CDKN1B(gene name)|psi-mi:CDKN1B(display_short)|uniprotkb:KIP1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1182050	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006828.2|dip:DIP-34546N|ensembl:ENSG00000121022(gene)|ensembl:ENST00000357849(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1990182"(exosomal secretion)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|interpro:IPR040961|mint:Q92905|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4F7O|rcsb pdb:4WSN|rcsb pdb:5JOG|rcsb pdb:5JOH|rcsb pdb:5M5Q|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664	refseq:NP_004055.1|rcsb pdb:1JSU|rcsb pdb:2AST|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6P8E|rcsb pdb:6P8F|rcsb pdb:6P8G|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5625900|reactome:R-HSA-5674400|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-9607240|reactome:R-HSA-9617828|reactome:R-HSA-9634638|reactome:R-HSA-9661069|ensembl:ENSG00000111276(gene)|ensembl:ENST00000228872(transcript)|ensembl:ENST00000614874(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001890"(placenta development)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048839"(inner ear development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090398"(cellular senescence)|go:"GO:1902746"(regulation of lens fiber cell differentiation)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029843|mint:P46527|rcsb pdb:1H27|dip:DIP-33341N	omim:608935(primary-reference)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)	-	-	figure legend:2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2007/01/05	2014/10/16	rogid:GMgH8dW3KWILX6Mr/+XrgAV3xY49606	rogid:UGcAvE0fJ9JmjMbh0s4ILpSzV+49606	intact-crc:F94237988ED4D02F|rigid:wQQSafvy80WrzWaV/NbkpGqfL1E	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P46527	uniprotkb:P09936	intact:EBI-519280|uniprotkb:Q16307|uniprotkb:Q9BUS6|ensembl:ENSP00000228872|ensembl:ENSP00000507272|uniprotkb:Q5U0H2	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	psi-mi:cdn1b_human(display_long)|uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym)|uniprotkb:p27Kip1(gene name synonym)|uniprotkb:CDKN1B(gene name)|psi-mi:CDKN1B(display_short)|uniprotkb:KIP1(gene name synonym)	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Caballero et al. (2002)	pubmed:12082530	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1182061	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004055.1|rcsb pdb:1JSU|rcsb pdb:2AST|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6P8E|rcsb pdb:6P8F|rcsb pdb:6P8G|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5625900|reactome:R-HSA-5674400|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-9607240|reactome:R-HSA-9617828|reactome:R-HSA-9634638|reactome:R-HSA-9661069|ensembl:ENSG00000111276(gene)|ensembl:ENST00000228872(transcript)|ensembl:ENST00000614874(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001890"(placenta development)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048839"(inner ear development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090398"(cellular senescence)|go:"GO:1902746"(regulation of lens fiber cell differentiation)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029843|mint:P46527|rcsb pdb:1H27|dip:DIP-33341N	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	omim:608935(primary-reference)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)	-	-	figure legend:2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma)	-	2007/01/05	2014/10/16	rogid:UGcAvE0fJ9JmjMbh0s4ILpSzV+49606	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	intact-crc:B38A7F3602DE2F11|rigid:pNC4nBA2rKDOcdqPZWKdC2I+LlA	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)