#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P42124	uniprotkb:Q9VEX9	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-871638|imex:IM-19918-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/02/19	2014/10/16	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	intact-crc:E966289D97CD0902|rigid:iW0UWdi8u5BLaHy+ydviOSGPGtM	false	sufficient binding region:512-760(IPR001214)	sufficient binding region:10-150	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9VEX9	uniprotkb:Q9VEX9	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203755|imex:IM-19918-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	go:"GO:0046983"(protein dimerization activity)	-	-	figure legend:1B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/02/19	2014/10/16	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	intact-crc:126117C4E15978D2|rigid:os98puGUEcLuEND5MFP6AR6g/80	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9VEX9	uniprotkb:P42124	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203762|imex:IM-19918-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	-	-	-	figure legend:1A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/02/19	2014/10/16	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	intact-crc:A31F053AFABA9366|rigid:iW0UWdi8u5BLaHy+ydviOSGPGtM	false	sufficient binding region:10-150	sufficient binding region:512-760|sufficient binding region:1-511	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42124	uniprotkb:Q9VEX9	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203787|imex:IM-19918-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	-	-	-	figure legend:2A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/02/19	2014/10/16	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	intact-crc:9A0C38362204C37C|rigid:iW0UWdi8u5BLaHy+ydviOSGPGtM	false	35s radiolabel:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42124	uniprotkb:Q9VEX9	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203801|imex:IM-19918-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	-	-	-	figure legend:2B, C, D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/02/19	2014/10/16	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	intact-crc:159368DAF6BB87AF|rigid:iW0UWdi8u5BLaHy+ydviOSGPGtM	false	glutathione s tranferase tag:?-?|sufficient binding region:512-605|sufficient binding region:377-446	35s radiolabel:?-?|sufficient binding region:10-150	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42124	uniprotkb:Q9VEX9	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203843|imex:IM-19918-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	-	-	-	figure legend:3A|comment:Interaction was detected in HA-esc embryos.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/02/19	2014/10/16	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	intact-crc:2D120C243E5678B3|rigid:iW0UWdi8u5BLaHy+ydviOSGPGtM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9VEX9	uniprotkb:P42124	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203851|imex:IM-19918-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	-	-	-	figure legend:3B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/02/19	2014/10/16	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	intact-crc:A2B62856E21593AE|rigid:iW0UWdi8u5BLaHy+ydviOSGPGtM	false	-	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9VEX9	uniprotkb:Q24338	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	intact:EBI-88911|ensemblmetazoa:FBpp0079907	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:esc_drome(display_long)|uniprotkb:esc(gene name)|psi-mi:esc(display_short)|uniprotkb:CG14941(orf name)|uniprotkb:Protein extra sex combs(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203872|imex:IM-19918-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	ensemblmetazoa:FBgn0000588(gene)|ensemblmetazoa:FBtr0080325(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016571"(histone methylation)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042802"(identical protein binding)|go:"GO:0048096"|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:Q24338|go:"GO:0016458"(obsolete gene silencing)|refseq:NP_477431.1|flybase:FBgn0000588|dip:DIP-20069N	-	-	-	figure legend:3C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/02/19	2014/10/16	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	rogid:owOOCkwb0LdPVnElMax3J1OIkEE7227	intact-crc:378570A4648FB171|rigid:7xWSmEmFOq7VlLl0jM3a5SGVdT4	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P42124	uniprotkb:Q9VEX9	intact:EBI-112315|uniprotkb:Q9VTA3|uniprotkb:B7Z0G2|ensemblmetazoa:FBpp0076008|ensemblmetazoa:FBpp0271846	intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506	psi-mi:ez_drome(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:"E(z)"(gene name)|psi-mi:"E(z)"(display_short)|uniprotkb:CG6502(orf name)|uniprotkb:Protein enhancer of zeste(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)	psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wang et al. (2002)	pubmed:12039038|imex:IM-19918	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1203889|imex:IM-19918-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524021.2|refseq:NP_001137932.1|flybase:FBgn0000629|dip:DIP-20386N|ensemblmetazoa:FBgn0000629(gene)|ensemblmetazoa:FBtr0076279(transcript)|ensemblmetazoa:FBtr0273338(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007411"(axon guidance)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016571"(histone methylation)|go:"GO:0022008"(neurogenesis)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:1902692"(regulation of neuroblast proliferation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:P42124|reactome:R-DME-2559580|reactome:R-DME-8943724	refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N	go:"GO:0035098"("ESC/E(Z) complex")	-	-	figure legend:4|complex-properties:dSAP18-containing complexes range in mass from 1100 to 450 kDa.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)	-	2007/02/19	2014/10/16	rogid:SgDch3Z90h2XcA4b2MqjzZN+gSI7227	rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227	intact-crc:05D0FEB877BAC7CA|rigid:iW0UWdi8u5BLaHy+ydviOSGPGtM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)