#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O59767 uniprotkb:P78972 intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" intact:EBI-1252744|ensemblfungi:"SPAC821.08c.1:pep" psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:slp1_schpo(display_long)|uniprotkb:slp1(gene name)|psi-mi:slp1(display_short)|uniprotkb:SPAC821.08c(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Millband et al. (2002) pubmed:11909965|imex:IM-18892 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269296|imex:IM-18892-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ refseq:NP_593161.1|dip:DIP-38036N|reactome:R-SPO-141405|reactome:R-SPO-141430|reactome:R-SPO-983168|ensemblfungi:SPAC821.08c(gene)|ensemblfungi:SPAC821.08c.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0007049"(cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0032153"(cell division site)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1905188"(positive regulation of metaphase/anaphase transition of meiosis I)|go:"GO:1905191"(positive regulation of metaphase/anaphase transition of meiosis II)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|interpro:IPR036322|rcsb pdb:4AEZ|reactome:R-SPO-174113|reactome:R-SPO-5689880 - crc64:EEC3EA6D3790C4BF crc64:52E021FD4EECE5DE comment:Cells were checkpoint-arrested.|figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/06/29 2014/10/16 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 rogid:sOmydsidXVRfPZ9canW51eh9+Vc284812 intact-crc:7C35435B82254014|rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O59767 uniprotkb:O14417 intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" intact:EBI-1269310|ensemblfungi:"SPBC20F10.06.1:pep" psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:mad2_schpo(display_long)|uniprotkb:mad2(gene name)|psi-mi:mad2(display_short)|uniprotkb:SPBC20F10.06(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Millband et al. (2002) pubmed:11909965|imex:IM-18892 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269296|imex:IM-18892-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ refseq:NP_596370.1|dip:DIP-38037N|ensemblfungi:SPBC20F10.06(gene)|ensemblfungi:SPBC20F10.06.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044779"(meiotic spindle checkpoint signaling)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1905318"(meiosis I spindle assembly checkpoint signaling)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|rcsb pdb:4AEZ|reactome:R-SPO-141405|reactome:R-SPO-141430 - crc64:EEC3EA6D3790C4BF crc64:DC9D1D213450C925 comment:Cells were checkpoint-arrested.|figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/06/29 2014/10/16 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 rogid:5G1YTWU4D7iYxw5IMofymMP9cyg284812 intact-crc:7C35435B82254014|rigid:zuUq0vF2FFFrptf5qQpmk6NayB4 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O42860 uniprotkb:O59767 intact:EBI-1269300|ensemblfungi:"SPAC23H3.08c.1:pep" intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" psi-mi:bub3_schpo(display_long)|uniprotkb:bub3(gene name)|psi-mi:bub3(display_short)|uniprotkb:SPAC23H3.08c(orf name) psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Millband et al. (2002) pubmed:11909965|imex:IM-18892 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1269364|imex:IM-18892-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593798.1|dip:DIP-39398N|ensemblfungi:SPAC23H3.08c(gene)|ensemblfungi:SPAC23H3.08c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0140499"(negative regulation of mitotic spindle assembly checkpoint signaling)|go:"GO:1990298"(bub1-bub3 complex)|go:"GO:1990758"(mitotic sister chromatid biorientation)|go:"GO:1990942"(mitotic metaphase chromosome recapture)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-SPO-141430 refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ - crc64:A5028C58CEBEED43 crc64:EEC3EA6D3790C4BF comment:Cells grown in presence of carbendazim to activate the spindle checkpoint.|figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/06/29 2014/10/16 rogid:d49VS+Ae+bNnSiMwJOrUy1NFKFs284812 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 intact-crc:B0579F4A5E50414D|rigid:wCdZA+TIVu09G6PAVdjm6srpi9s false - green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y812 uniprotkb:O59767 intact:EBI-1153281|ensemblfungi:"SPBC1105.17.1:pep" intact:EBI-1269284|ensemblfungi:"SPCC1795.01c.1:pep" psi-mi:cenpa_schpo(display_long)|uniprotkb:cnp1(gene name)|psi-mi:cnp1(display_short)|uniprotkb:sim2(gene name synonym)|uniprotkb:SPBC1105.17(orf name)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:Silencing in the middle of the centromere protein 2(gene name synonym) psi-mi:mad3_schpo(display_long)|uniprotkb:mad3(gene name)|psi-mi:mad3(display_short)|uniprotkb:SPCC1795.01c(orf name)|uniprotkb:SPCC895.02(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Millband et al. (2002) pubmed:11909965|imex:IM-18892 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1270971|imex:IM-18892-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596473.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|ensemblfungi:SPBC1105.17(gene)|ensemblfungi:SPBC1105.17.1(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061638"(CENP-A containing chromatin)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1990758"(mitotic sister chromatid biorientation)|reactome:R-SPO-2299718|reactome:R-SPO-2559580|reactome:R-SPO-3214841|reactome:R-SPO-3214842|reactome:R-SPO-3214847|reactome:R-SPO-3214858|reactome:R-SPO-5578749|reactome:R-SPO-5693565|reactome:R-SPO-73772|reactome:R-SPO-983231 refseq:NP_588043.2|dip:DIP-39397N|ensemblfungi:SPCC1795.01c(gene)|ensemblfungi:SPCC1795.01c.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:4AEZ go:"GO:0000776"(kinetochore) - crc64:EEC3EA6D3790C4BF figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/06/29 2014/10/16 rogid:AaYRJN1kS2Cf0jiTUDE0EIsDFJw284812 rogid:SP8jTFSj21n8OrXajC/gA1GW8RQ284812 intact-crc:BEC5F757833FF5EA|rigid:gvnK2zYfBUsuzlyrzmU2e9foYUI false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)