#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40046 uniprotkb:P43585 intact:EBI-20513|uniprotkb:D3DLX7|ensemblfungi:YER072W intact:EBI-22750|uniprotkb:D6VTM5|ensemblfungi:YFL004W psi-mi:vtc1_yeast(display_long)|uniprotkb:VTC1(gene name)|psi-mi:VTC1(display_short)|uniprotkb:PHM4(gene name synonym)|uniprotkb:Phosphate metabolism protein 4(gene name synonym)|uniprotkb:Negative regulator of CDC42 protein 1(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:YER072W(locus name) psi-mi:vtc2_yeast(display_long)|uniprotkb:YFL004W(locus name)|uniprotkb:VTC2(gene name)|psi-mi:VTC2(display_short)|uniprotkb:PHM1(gene name synonym)|uniprotkb:Phosphate metabolism protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Muller et al. (2002) pubmed:11823419|imex:IM-19556 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1255052|imex:IM-19556-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000874|interpro:IPR003807(Protein of unknown function DUF202)|refseq:NP_010995.1|ensemblfungi:YER072W(gene)|ensemblfungi:YER072W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003729"(mRNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031310"(intrinsic component of vacuolar membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|mint:P40046 refseq:NP_116651.1|sgd:S000001890|dip:DIP-7596N|mint:P43585|ensemblfungi:YFL004W(gene)|ensemblfungi:YFL004W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0008104"(protein localization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048016"(inositol phosphate-mediated signaling)|interpro:IPR003807(Protein of unknown function DUF202)|interpro:IPR004331(SPX, N-terminal)|interpro:IPR018966|rcsb pdb:3G3O go:"GO:0005774"(vacuolar membrane) - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/23 2014/10/16 rogid:Av0l+cDYWjRtvTIM7rKGYZQK5UM559292 rogid:XyDU84ncgW6ZvyB6NWNaq/YtxrM559292 intact-crc:6B2044E927BC9015|rigid:8GhC0XzePm8IIf3ybBmWz1+6V0c false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P40046 uniprotkb:P47075 intact:EBI-20513|uniprotkb:D3DLX7|ensemblfungi:YER072W intact:EBI-25789|uniprotkb:Q7Z872|uniprotkb:Q86ZR4|uniprotkb:D6VWG5|ensemblfungi:YJL012C psi-mi:vtc1_yeast(display_long)|uniprotkb:VTC1(gene name)|psi-mi:VTC1(display_short)|uniprotkb:PHM4(gene name synonym)|uniprotkb:Phosphate metabolism protein 4(gene name synonym)|uniprotkb:Negative regulator of CDC42 protein 1(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:YER072W(locus name) psi-mi:vtc4_yeast(display_long)|uniprotkb:VTC4(gene name)|psi-mi:VTC4(display_short)|uniprotkb:PHM3(gene name synonym)|uniprotkb:YJL012C(locus name)|uniprotkb:J1345(orf name)|uniprotkb:Phosphate metabolism protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Muller et al. (2002) pubmed:11823419|imex:IM-19556 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1255052|imex:IM-19556-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000874|interpro:IPR003807(Protein of unknown function DUF202)|refseq:NP_010995.1|ensemblfungi:YER072W(gene)|ensemblfungi:YER072W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003729"(mRNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031310"(intrinsic component of vacuolar membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|mint:P40046 refseq:NP_012522.2|sgd:S000003549|dip:DIP-5608N|ensemblfungi:YJL012C(gene)|ensemblfungi:YJL012C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0008976"(polyphosphate kinase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031310"(intrinsic component of vacuolar membrane)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0048016"(inositol phosphate-mediated signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR003807(Protein of unknown function DUF202)|interpro:IPR004331(SPX, N-terminal)|interpro:IPR018966|interpro:IPR042267|rcsb pdb:3G3Q|rcsb pdb:3G3R|rcsb pdb:3G3T|rcsb pdb:3G3U|rcsb pdb:5IIG|rcsb pdb:5IIQ|rcsb pdb:5IIT|rcsb pdb:5LNC|go:"GO:0042144"(vacuole fusion, non-autophagic) go:"GO:0005774"(vacuolar membrane) - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/23 2014/10/16 rogid:Av0l+cDYWjRtvTIM7rKGYZQK5UM559292 rogid:hosvjdOitK49z+Tp57o1cYub4Qs559292 intact-crc:6B2044E927BC9015|rigid:8GhC0XzePm8IIf3ybBmWz1+6V0c false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P40046 uniprotkb:Q02725 intact:EBI-20513|uniprotkb:D3DLX7|ensemblfungi:YER072W intact:EBI-36919|uniprotkb:D6W3Z3|ensemblfungi:YPL019C psi-mi:vtc1_yeast(display_long)|uniprotkb:VTC1(gene name)|psi-mi:VTC1(display_short)|uniprotkb:PHM4(gene name synonym)|uniprotkb:Phosphate metabolism protein 4(gene name synonym)|uniprotkb:Negative regulator of CDC42 protein 1(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:YER072W(locus name) psi-mi:vtc3_yeast(display_long)|uniprotkb:YPL019C(locus name)|uniprotkb:VTC3(gene name)|psi-mi:VTC3(display_short)|uniprotkb:PHM2(gene name synonym)|uniprotkb:Phosphate metabolism protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Muller et al. (2002) pubmed:11823419|imex:IM-19556 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1255052|imex:IM-19556-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000874|interpro:IPR003807(Protein of unknown function DUF202)|refseq:NP_010995.1|ensemblfungi:YER072W(gene)|ensemblfungi:YER072W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003729"(mRNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031310"(intrinsic component of vacuolar membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|mint:P40046 refseq:NP_015306.1|sgd:S000005940|dip:DIP-2000N|ensemblfungi:YPL019C(gene)|ensemblfungi:YPL019C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048016"(inositol phosphate-mediated signaling)|interpro:IPR003807(Protein of unknown function DUF202)|interpro:IPR004331(SPX, N-terminal)|interpro:IPR018966 go:"GO:0005774"(vacuolar membrane) - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/23 2014/10/16 rogid:Av0l+cDYWjRtvTIM7rKGYZQK5UM559292 rogid:za1pUKYuyiKrn7OgawGUVPBtLaQ559292 intact-crc:6B2044E927BC9015|rigid:8GhC0XzePm8IIf3ybBmWz1+6V0c false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P40046 uniprotkb:Q12255 intact:EBI-20513|uniprotkb:D3DLX7|ensemblfungi:YER072W intact:EBI-35465|uniprotkb:D6VY93|ensemblfungi:YLR093C psi-mi:vtc1_yeast(display_long)|uniprotkb:VTC1(gene name)|psi-mi:VTC1(display_short)|uniprotkb:PHM4(gene name synonym)|uniprotkb:Phosphate metabolism protein 4(gene name synonym)|uniprotkb:Negative regulator of CDC42 protein 1(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:YER072W(locus name) psi-mi:nyv1_yeast(display_long)|uniprotkb:NYV1(gene name)|psi-mi:NYV1(display_short)|uniprotkb:Synaptobrevin NYV1(gene name synonym)|uniprotkb:New v-SNARE 1(gene name synonym)|uniprotkb:MAM2(gene name synonym)|uniprotkb:YLR093C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Muller et al. (2002) pubmed:11823419|imex:IM-19556 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1255066|imex:IM-19556-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000874|interpro:IPR003807(Protein of unknown function DUF202)|refseq:NP_010995.1|ensemblfungi:YER072W(gene)|ensemblfungi:YER072W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003729"(mRNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031310"(intrinsic component of vacuolar membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|mint:P40046 refseq:NP_013194.2|sgd:S000004083|mint:Q12255|dip:DIP-2248N|ensemblfungi:YLR093C(gene)|ensemblfungi:YLR093C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001388(Synaptobrevin)|interpro:IPR019005|interpro:IPR038426|interpro:IPR042855|rcsb pdb:2FZ0|reactome:R-SCE-199992 - - crc64:494B587CF0F85997 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/23 2014/10/16 rogid:Av0l+cDYWjRtvTIM7rKGYZQK5UM559292 rogid:rmpyOWgiP8SZMWZJNLvCQQeWEYw559292 intact-crc:08050E80B769153A|rigid:yih5ck7MOqvB5K0jSXwMVqLJN5o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32563 uniprotkb:P47075 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-25789|uniprotkb:Q7Z872|uniprotkb:Q86ZR4|uniprotkb:D6VWG5|ensemblfungi:YJL012C psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:vtc4_yeast(display_long)|uniprotkb:VTC4(gene name)|psi-mi:VTC4(display_short)|uniprotkb:PHM3(gene name synonym)|uniprotkb:YJL012C(locus name)|uniprotkb:J1345(orf name)|uniprotkb:Phosphate metabolism protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2002) pubmed:11823419|imex:IM-19556 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1255077|imex:IM-19556-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 refseq:NP_012522.2|sgd:S000003549|dip:DIP-5608N|ensemblfungi:YJL012C(gene)|ensemblfungi:YJL012C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0008976"(polyphosphate kinase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031310"(intrinsic component of vacuolar membrane)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0048016"(inositol phosphate-mediated signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR003807(Protein of unknown function DUF202)|interpro:IPR004331(SPX, N-terminal)|interpro:IPR018966|interpro:IPR042267|rcsb pdb:3G3Q|rcsb pdb:3G3R|rcsb pdb:3G3T|rcsb pdb:3G3U|rcsb pdb:5IIG|rcsb pdb:5IIQ|rcsb pdb:5IIT|rcsb pdb:5LNC|go:"GO:0042144"(vacuole fusion, non-autophagic) - crc64:77709A914410CD4D - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/23 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:hosvjdOitK49z+Tp57o1cYub4Qs559292 intact-crc:AE5A94127333D366|rigid:3AKz+V/xlcgBgqKA2NhosFQTKbk false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32563 uniprotkb:P32366 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-20201|uniprotkb:D6VZ81|ensemblfungi:YLR447C psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:va0d_yeast(display_long)|uniprotkb:VMA6(gene name)|psi-mi:VMA6(display_short)|uniprotkb:YLR447C(locus name)|uniprotkb:L9324.8(orf name)|uniprotkb:Vacuolar proton pump subunit d(gene name synonym)|uniprotkb:V-ATPase 39 kDa subunit(gene name synonym)|uniprotkb:V-ATPase subunit M39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2002) pubmed:11823419|imex:IM-19556 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1255077|imex:IM-19556-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 sgd:S000004439|refseq:NP_013552.3|mint:P32366|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|ensemblfungi:YLR447C(gene)|ensemblfungi:YLR447C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|rcsb pdb:6PE4|dip:DIP-1737N - crc64:77709A914410CD4D crc64:53A19450CAF35632 figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/23 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:Ux3Cd8Fl9t/GGgcKAzJevZQFWnE559292 intact-crc:AE5A94127333D366|rigid:3AKz+V/xlcgBgqKA2NhosFQTKbk false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32563 uniprotkb:P40046 intact:EBI-20455|uniprotkb:D6W2X0|ensemblfungi:YOR270C intact:EBI-20513|uniprotkb:D3DLX7|ensemblfungi:YER072W psi-mi:vph1_yeast(display_long)|uniprotkb:VPH1(gene name)|psi-mi:VPH1(display_short)|uniprotkb:Vacuolar proton pump a subunit(gene name synonym)|uniprotkb:V-ATPase 95 kDa subunit(gene name synonym)|uniprotkb:Vacuolar pH protein 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase subunit a 1(gene name synonym)|uniprotkb:YOR270C(locus name) psi-mi:vtc1_yeast(display_long)|uniprotkb:VTC1(gene name)|psi-mi:VTC1(display_short)|uniprotkb:PHM4(gene name synonym)|uniprotkb:Phosphate metabolism protein 4(gene name synonym)|uniprotkb:Negative regulator of CDC42 protein 1(gene name synonym)|uniprotkb:NRF1(gene name synonym)|uniprotkb:YER072W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2002) pubmed:11823419|imex:IM-19556 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1255077|imex:IM-19556-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005796|refseq:NP_014913.3|ensemblfungi:YOR270C(gene)|ensemblfungi:YOR270C_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0034622"|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:0071469"(cellular response to alkaline pH)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|rcsb pdb:2JTW|rcsb pdb:2NVJ|rcsb pdb:2RPW|rcsb pdb:3J9T|go:"GO:0007035"(vacuolar acidification)|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5I1M|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6HH0|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2960N|mint:P32563 sgd:S000000874|interpro:IPR003807(Protein of unknown function DUF202)|refseq:NP_010995.1|ensemblfungi:YER072W(gene)|ensemblfungi:YER072W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003729"(mRNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006797"(polyphosphate metabolic process)|go:"GO:0006799"(polyphosphate biosynthetic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031310"(intrinsic component of vacuolar membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033254"(vacuolar transporter chaperone complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|mint:P40046 - crc64:77709A914410CD4D - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/23 2014/10/16 rogid:c+aKW/ZUnBlGW7ZqOLD/0mpICdQ559292 rogid:Av0l+cDYWjRtvTIM7rKGYZQK5UM559292 intact-crc:AE5A94127333D366|rigid:3AKz+V/xlcgBgqKA2NhosFQTKbk false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)