#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75807 uniprotkb:Q13522 intact:EBI-714746|uniprotkb:Q6IA96|uniprotkb:Q9NVU6|intact:EBI-28977765|ensembl:ENSP00000200453|uniprotkb:B4DKQ3 intact:EBI-1568511|uniprotkb:Q6IB01|uniprotkb:Q8TBJ2|uniprotkb:Q8WWV2|ensembl:ENSP00000257905 psi-mi:pr15a_human(display_long)|uniprotkb:Myeloid differentiation primary response protein MyD116 homolog(gene name synonym)|uniprotkb:PPP1R15A(gene name)|psi-mi:PPP1R15A(display_short)|uniprotkb:GADD34(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD34(gene name synonym) psi-mi:ppr1a_human(display_long)|uniprotkb:Protein phosphatase inhibitor 1(gene name synonym)|uniprotkb:PPP1R1A(gene name)|psi-mi:PPP1R1A(display_short)|uniprotkb:IPP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Connor et al. (2001) pubmed:11564868|imex:IM-19777 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1568522|imex:IM-19777-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055145.3|ensembl:ENSG00000087074(gene)|ensembl:ENST00000200453(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|ensembl:ENSP00000200453|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032058"(positive regulation of translational initiation in response to stress)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1902310"(positive regulation of peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903917"(positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation)|interpro:IPR019523|mint:O75807|rcsb pdb:4XPN|reactome:R-HSA-2173788|reactome:R-HSA-9648895 refseq:NP_006732.3|ensembl:ENSG00000135447(gene)|ensembl:ENST00000257905(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR008466(Protein phosphatase inhibitor, 1DARPP-32) - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/14 2014/10/16 rogid:2pmlIgM2OX5qK5Bvb1p9x9ZERLw9606 rogid:67WpvtCHsPcMvjEvaE5JSFAqUn09606 intact-crc:67C72E4158944DD6|rigid:4Tb5ZSa5FEBP33hg68VDGzhO2aA false sufficient binding region:233-674 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13522 uniprotkb:O75807 intact:EBI-1568511|uniprotkb:Q6IB01|uniprotkb:Q8TBJ2|uniprotkb:Q8WWV2|ensembl:ENSP00000257905 intact:EBI-714746|uniprotkb:Q6IA96|uniprotkb:Q9NVU6|intact:EBI-28977765|ensembl:ENSP00000200453|uniprotkb:B4DKQ3 psi-mi:ppr1a_human(display_long)|uniprotkb:Protein phosphatase inhibitor 1(gene name synonym)|uniprotkb:PPP1R1A(gene name)|psi-mi:PPP1R1A(display_short)|uniprotkb:IPP1(gene name synonym) psi-mi:pr15a_human(display_long)|uniprotkb:Myeloid differentiation primary response protein MyD116 homolog(gene name synonym)|uniprotkb:PPP1R15A(gene name)|psi-mi:PPP1R15A(display_short)|uniprotkb:GADD34(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD34(gene name synonym) psi-mi:"MI:0018"(two hybrid) Connor et al. (2001) pubmed:11564868|imex:IM-19777 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1568533|imex:IM-19777-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006732.3|ensembl:ENSG00000135447(gene)|ensembl:ENST00000257905(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR008466(Protein phosphatase inhibitor, 1DARPP-32) refseq:NP_055145.3|ensembl:ENSG00000087074(gene)|ensembl:ENST00000200453(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|ensembl:ENSP00000200453|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032058"(positive regulation of translational initiation in response to stress)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1902310"(positive regulation of peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903917"(positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation)|interpro:IPR019523|mint:O75807|rcsb pdb:4XPN|reactome:R-HSA-2173788|reactome:R-HSA-9648895 - - - figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/14 2014/10/16 rogid:67WpvtCHsPcMvjEvaE5JSFAqUn09606 rogid:2pmlIgM2OX5qK5Bvb1p9x9ZERLw9606 intact-crc:73141DE2D7622274|rigid:4Tb5ZSa5FEBP33hg68VDGzhO2aA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32598 uniprotkb:Q13522 intact:EBI-13715|ensemblfungi:YER133W|uniprotkb:D3DM39 intact:EBI-1568511|uniprotkb:Q6IB01|uniprotkb:Q8TBJ2|uniprotkb:Q8WWV2|ensembl:ENSP00000257905 psi-mi:pp12_yeast(display_long)|uniprotkb:GLC7(gene name)|psi-mi:GLC7(display_short)|uniprotkb:CID1(gene name synonym)|uniprotkb:DIS2(gene name synonym)|uniprotkb:YER133W(locus name) psi-mi:ppr1a_human(display_long)|uniprotkb:Protein phosphatase inhibitor 1(gene name synonym)|uniprotkb:PPP1R1A(gene name)|psi-mi:PPP1R1A(display_short)|uniprotkb:IPP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Connor et al. (2001) pubmed:11564868|imex:IM-19777 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1568538|imex:IM-19777-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER133W(gene)|ensemblfungi:YER133W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000776"(kinetochore)|go:"GO:0001400"(mating projection base)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006397"(mRNA processing)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007116"(regulation of cell budding)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0005816"(spindle pole body)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|sgd:S000000935|refseq:NP_011059.3|mint:P32598|dip:DIP-1336N refseq:NP_006732.3|ensembl:ENSG00000135447(gene)|ensembl:ENST00000257905(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR008466(Protein phosphatase inhibitor, 1DARPP-32) - crc64:71B20E3A4ED93235 - figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/14 2014/10/16 rogid:wXXOB38if1fxEN0yLxeYTCXsuyU559292 rogid:67WpvtCHsPcMvjEvaE5JSFAqUn09606 intact-crc:48B8C0498EB7A20E|rigid:Ic2Ut+sMFGv7UWebtrDE4K9WuUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13522 uniprotkb:O75807 intact:EBI-1568511|uniprotkb:Q6IB01|uniprotkb:Q8TBJ2|uniprotkb:Q8WWV2|ensembl:ENSP00000257905 intact:EBI-714746|uniprotkb:Q6IA96|uniprotkb:Q9NVU6|intact:EBI-28977765|ensembl:ENSP00000200453|uniprotkb:B4DKQ3 psi-mi:ppr1a_human(display_long)|uniprotkb:Protein phosphatase inhibitor 1(gene name synonym)|uniprotkb:PPP1R1A(gene name)|psi-mi:PPP1R1A(display_short)|uniprotkb:IPP1(gene name synonym) psi-mi:pr15a_human(display_long)|uniprotkb:Myeloid differentiation primary response protein MyD116 homolog(gene name synonym)|uniprotkb:PPP1R15A(gene name)|psi-mi:PPP1R15A(display_short)|uniprotkb:GADD34(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD34(gene name synonym) psi-mi:"MI:0096"(pull down) Connor et al. (2001) pubmed:11564868|imex:IM-19777 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1568552|imex:IM-19777-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006732.3|ensembl:ENSG00000135447(gene)|ensembl:ENST00000257905(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR008466(Protein phosphatase inhibitor, 1DARPP-32) refseq:NP_055145.3|ensembl:ENSG00000087074(gene)|ensembl:ENST00000200453(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|ensembl:ENSP00000200453|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032058"(positive regulation of translational initiation in response to stress)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1902310"(positive regulation of peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903917"(positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation)|interpro:IPR019523|mint:O75807|rcsb pdb:4XPN|reactome:R-HSA-2173788|reactome:R-HSA-9648895 - - - figure legend:Figs. 2 and 3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/14 2014/10/16 rogid:67WpvtCHsPcMvjEvaE5JSFAqUn09606 rogid:2pmlIgM2OX5qK5Bvb1p9x9ZERLw9606 intact-crc:1C4B2D794240BEED|rigid:4Tb5ZSa5FEBP33hg68VDGzhO2aA false his tag:?-?|sufficient binding region:143-171 sufficient binding region:233-674|his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:6925" uniprotkb:O75807 intact:EBI-1568671 intact:EBI-714746|uniprotkb:Q6IA96|uniprotkb:Q9NVU6|intact:EBI-28977765|ensembl:ENSP00000200453|uniprotkb:B4DKQ3 psi-mi:microcystin-lr(display_short)|psi-mi:"CHEBI:6925"(display_long) psi-mi:pr15a_human(display_long)|uniprotkb:Myeloid differentiation primary response protein MyD116 homolog(gene name synonym)|uniprotkb:PPP1R15A(gene name)|psi-mi:PPP1R15A(display_short)|uniprotkb:GADD34(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD34(gene name synonym) psi-mi:"MI:0096"(pull down) Connor et al. (2001) pubmed:11564868|imex:IM-19777 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1568650|imex:IM-19777-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_055145.3|ensembl:ENSG00000087074(gene)|ensembl:ENST00000200453(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|ensembl:ENSP00000200453|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032058"(positive regulation of translational initiation in response to stress)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1902310"(positive regulation of peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903917"(positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation)|interpro:IPR019523|mint:O75807|rcsb pdb:4XPN|reactome:R-HSA-2173788|reactome:R-HSA-9648895 - - - figure legend:Fig 4c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/14 2014/10/16 - rogid:2pmlIgM2OX5qK5Bvb1p9x9ZERLw9606 intact-crc:820FC1C1C959D2F7 false - flag tag:?-?|sufficient binding region:483-610 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13522 uniprotkb:O75807 intact:EBI-1568511|uniprotkb:Q6IB01|uniprotkb:Q8TBJ2|uniprotkb:Q8WWV2|ensembl:ENSP00000257905 intact:EBI-714746|uniprotkb:Q6IA96|uniprotkb:Q9NVU6|intact:EBI-28977765|ensembl:ENSP00000200453|uniprotkb:B4DKQ3 psi-mi:ppr1a_human(display_long)|uniprotkb:Protein phosphatase inhibitor 1(gene name synonym)|uniprotkb:PPP1R1A(gene name)|psi-mi:PPP1R1A(display_short)|uniprotkb:IPP1(gene name synonym) psi-mi:pr15a_human(display_long)|uniprotkb:Myeloid differentiation primary response protein MyD116 homolog(gene name synonym)|uniprotkb:PPP1R15A(gene name)|psi-mi:PPP1R15A(display_short)|uniprotkb:GADD34(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD34(gene name synonym) psi-mi:"MI:0096"(pull down) Connor et al. (2001) pubmed:11564868|imex:IM-19777 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1568685|imex:IM-19777-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006732.3|ensembl:ENSG00000135447(gene)|ensembl:ENST00000257905(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR008466(Protein phosphatase inhibitor, 1DARPP-32) refseq:NP_055145.3|ensembl:ENSG00000087074(gene)|ensembl:ENST00000200453(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|ensembl:ENSP00000200453|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032058"(positive regulation of translational initiation in response to stress)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1902310"(positive regulation of peptidyl-serine dephosphorylation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903917"(positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation)|interpro:IPR019523|mint:O75807|rcsb pdb:4XPN|reactome:R-HSA-2173788|reactome:R-HSA-9648895 - - - figure legend:Fig. 4D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/14 2014/10/16 rogid:67WpvtCHsPcMvjEvaE5JSFAqUn09606 rogid:2pmlIgM2OX5qK5Bvb1p9x9ZERLw9606 intact-crc:5E706BC26ED9B03E|rigid:4Tb5ZSa5FEBP33hg68VDGzhO2aA false - flag tag:?-?|sufficient binding region:180-483 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)