#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UNA1 uniprotkb:Q6P5Z2 intact:EBI-1390913|uniprotkb:O75117|uniprotkb:Q9BYS6|uniprotkb:Q9BYS7|uniprotkb:Q9UJ00|uniprotkb:Q5D035|ensembl:ENSP00000274498 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg26_human(display_long)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0018"(two hybrid) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129080.1|refseq:NP_055886.1|ensembl:ENSG00000145819(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000274498(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR030061|interpro:IPR035481|interpro:IPR035483|interpro:IPR036028|mint:Q9UNA1|rcsb pdb:1UGV|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Table 1 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/04 2014/10/16 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:6CD85234933C44FD|rigid:eXA9j9wrs/ZO7DQx+ZhUb1iiapY false binding-associated region:626-759 binding-associated region:465-557 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A1A4S6 uniprotkb:Q6P5Z2 intact:EBI-1390944|uniprotkb:Q2VPC4|uniprotkb:Q2VPC5|uniprotkb:Q96EV3|uniprotkb:Q96S75|uniprotkb:A1L0S5|ensembl:ENSP00000336923 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg10_human(display_long)|uniprotkb:ARHGAP10(gene name)|psi-mi:ARHGAP10(display_short)|uniprotkb:GRAF2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase 2(gene name synonym)|uniprotkb:Graf-related protein 2(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0018"(two hybrid) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078881.3|ensembl:ENSG00000071205(gene)|ensembl:ENST00000336498(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|rcsb pdb:2MIO|reactome:R-HSA-211728|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Table 1 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/04 2014/10/16 rogid:gbHj2b+qPHC9tKs3Y3eRicrt8mk9606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:EF0E76803746E7A0|rigid:DQjw9ijfO7DTUENs8EdktKj+6zI false binding-associated region:?-? binding-associated region:465-557 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNA1 uniprotkb:Q6P5Z2 intact:EBI-1390913|uniprotkb:O75117|uniprotkb:Q9BYS6|uniprotkb:Q9BYS7|uniprotkb:Q9UJ00|uniprotkb:Q5D035|ensembl:ENSP00000274498 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg26_human(display_long)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0096"(pull down) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390986 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129080.1|refseq:NP_055886.1|ensembl:ENSG00000145819(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000274498(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR030061|interpro:IPR035481|interpro:IPR035483|interpro:IPR036028|mint:Q9UNA1|rcsb pdb:1UGV|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Fig 5A taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/04 2014/10/16 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:D0047C30DEF37B66|rigid:eXA9j9wrs/ZO7DQx+ZhUb1iiapY false binding-associated region:596-759|glutathione s tranferase tag:?-? maltose binding protein tag:?-?|sufficient binding region:301-610 - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:A1A4S6 uniprotkb:Q6P5Z2 intact:EBI-1390944|uniprotkb:Q2VPC4|uniprotkb:Q2VPC5|uniprotkb:Q96EV3|uniprotkb:Q96S75|uniprotkb:A1L0S5|ensembl:ENSP00000336923 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg10_human(display_long)|uniprotkb:ARHGAP10(gene name)|psi-mi:ARHGAP10(display_short)|uniprotkb:GRAF2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase 2(gene name synonym)|uniprotkb:Graf-related protein 2(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0096"(pull down) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390996 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078881.3|ensembl:ENSG00000071205(gene)|ensembl:ENST00000336498(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|rcsb pdb:2MIO|reactome:R-HSA-211728|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Fig 5A taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/04 2014/10/16 rogid:gbHj2b+qPHC9tKs3Y3eRicrt8mk9606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:1CB23253C88DCAFF|rigid:DQjw9ijfO7DTUENs8EdktKj+6zI false glutathione s tranferase tag:?-?|binding-associated region:?-? maltose binding protein tag:?-?|sufficient binding region:301-610 - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:A1A4S6 uniprotkb:Q6P5Z2 intact:EBI-1390944|uniprotkb:Q2VPC4|uniprotkb:Q2VPC5|uniprotkb:Q96EV3|uniprotkb:Q96S75|uniprotkb:A1L0S5|ensembl:ENSP00000336923 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg10_human(display_long)|uniprotkb:ARHGAP10(gene name)|psi-mi:ARHGAP10(display_short)|uniprotkb:GRAF2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase 2(gene name synonym)|uniprotkb:Graf-related protein 2(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0096"(pull down) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1391007 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078881.3|ensembl:ENSG00000071205(gene)|ensembl:ENST00000336498(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|rcsb pdb:2MIO|reactome:R-HSA-211728|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Fig 5B taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/04 2014/10/16 rogid:gbHj2b+qPHC9tKs3Y3eRicrt8mk9606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:377720B4707FB875|rigid:DQjw9ijfO7DTUENs8EdktKj+6zI false glutathione s tranferase tag:?-?|binding-associated region:?-? maltose binding protein tag:?-? - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9UNA1 uniprotkb:Q6P5Z2 intact:EBI-1390913|uniprotkb:O75117|uniprotkb:Q9BYS6|uniprotkb:Q9BYS7|uniprotkb:Q9UJ00|uniprotkb:Q5D035|ensembl:ENSP00000274498 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg26_human(display_long)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0096"(pull down) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1391018 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129080.1|refseq:NP_055886.1|ensembl:ENSG00000145819(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000274498(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR030061|interpro:IPR035481|interpro:IPR035483|interpro:IPR036028|mint:Q9UNA1|rcsb pdb:1UGV|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Fig 5B taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/04 2014/10/16 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:3F9C47C2FB2FCC6C|rigid:eXA9j9wrs/ZO7DQx+ZhUb1iiapY false binding-associated region:596-759|glutathione s tranferase tag:?-? maltose binding protein tag:?-? - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:A1A4S6 uniprotkb:Q6P5Z2 intact:EBI-1390944|uniprotkb:Q2VPC4|uniprotkb:Q2VPC5|uniprotkb:Q96EV3|uniprotkb:Q96S75|uniprotkb:A1L0S5|ensembl:ENSP00000336923 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg10_human(display_long)|uniprotkb:ARHGAP10(gene name)|psi-mi:ARHGAP10(display_short)|uniprotkb:GRAF2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase 2(gene name synonym)|uniprotkb:Graf-related protein 2(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078881.3|ensembl:ENSG00000071205(gene)|ensembl:ENST00000336498(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|rcsb pdb:2MIO|reactome:R-HSA-211728|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Fig 6 taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2007/09/04 2014/10/16 rogid:gbHj2b+qPHC9tKs3Y3eRicrt8mk9606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:8FCEC6B2043BEA98|rigid:DQjw9ijfO7DTUENs8EdktKj+6zI false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UNA1 uniprotkb:Q6P5Z2 intact:EBI-1390913|uniprotkb:O75117|uniprotkb:Q9BYS6|uniprotkb:Q9BYS7|uniprotkb:Q9UJ00|uniprotkb:Q5D035|ensembl:ENSP00000274498 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:rhg26_human(display_long)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shibata et al. (2001) pubmed:11432776|mint:MINT-5214217 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1390973 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129080.1|refseq:NP_055886.1|ensembl:ENSG00000145819(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000274498(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR030061|interpro:IPR035481|interpro:IPR035483|interpro:IPR036028|mint:Q9UNA1|rcsb pdb:1UGV|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423 refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Fig 6 taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2007/09/04 2014/10/16 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 intact-crc:392346303305BA84|rigid:eXA9j9wrs/ZO7DQx+ZhUb1iiapY false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)