#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P56546	uniprotkb:Q03112	intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269	intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90	psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short)	psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Palmer et al. (2001)	pubmed:11328817|imex:IM-19966|mint:MINT-5213977	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1384894|imex:IM-19966-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265	refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1	-	-	-	figure legend:1 A, B, C, 4 A, B|comment:"Deletion of site a of Evi-1 (aa 553-559) impairs this interaction but deletion of site b of Evi-1 (aa 584-590) abolishes this interaction."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/08/16	2018/04/06	rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090	rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606	intact-crc:F4E98B7345729054|rigid:NY6kSITVkWTWGqtJMFO1DCgJJjE	false	-	necessary binding region:702-819|binding-associated region:741-747|binding-associated region:772-778	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56546	uniprotkb:Q03112	intact:EBI-1384883|uniprotkb:O54855|uniprotkb:O88462|ensembl:ENSMUSP00000033269	intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90	psi-mi:ctbp2_mouse(display_long)|uniprotkb:Ctbp2(gene name)|psi-mi:Ctbp2(display_short)	psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Palmer et al. (2001)	pubmed:11328817|imex:IM-19966|mint:MINT-5213977	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1388290|imex:IM-19966-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164215.1|refseq:NP_034110.1|refseq:XP_006507371.1|refseq:XP_006507372.1|refseq:XP_006507373.1|refseq:XP_006507374.1|refseq:XP_006507375.1|ensembl:ENSMUSG00000030970(gene)|ensembl:ENSMUST00000033269(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56546|reactome:R-MMU-4641265	refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1	-	-	-	figure legend:2 B|delivery method:P56546; Q03112 transfection|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-bosc_23)|taxid:9606(Homo sapiens embryonic kidney cell line BOSC-23)	-	2007/08/16	2018/04/06	rogid:3fTZKboxkpsDFUB+Kh0AMeIQNYI10090	rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606	intact-crc:E6C907C7618956B1|rigid:NY6kSITVkWTWGqtJMFO1DCgJJjE	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)