#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53973	uniprotkb:P16649	intact:EBI-8206|uniprotkb:D6W1F8|ensemblfungi:YNL021W	intact:EBI-19654|uniprotkb:P17995|uniprotkb:P18323|uniprotkb:D6VR85|ensemblfungi:YCR084C	psi-mi:hda1_yeast(display_long)|uniprotkb:HDA1(gene name)|psi-mi:HDA1(display_short)|uniprotkb:N2819(orf name)|uniprotkb:YNL021W(locus name)	psi-mi:tup1_yeast(display_long)|uniprotkb:TUP1(gene name)|psi-mi:TUP1(display_short)|uniprotkb:AAR1(gene name synonym)|uniprotkb:AER2(gene name synonym)|uniprotkb:AMM1(gene name synonym)|uniprotkb:CYC9(gene name synonym)|uniprotkb:FLK1(gene name synonym)|uniprotkb:SFL2(gene name synonym)|uniprotkb:UMR7(gene name synonym)|uniprotkb:YCR084C(locus name)|uniprotkb:YCR84C(orf name)|uniprotkb:Glucose repression regulatory protein TUP1(gene name synonym)|uniprotkb:Flocculation suppressor protein(gene name synonym)|uniprotkb:Repressor AER2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wu et al. (2001)	pubmed:11172717|imex:IM-19439	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1370407|imex:IM-19439-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014377.1|sgd:S000004966|mint:P53973|dip:DIP-1360N|ensemblfungi:YNL021W(gene)|ensemblfungi:YNL021W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070823"(HDA1 complex)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR017321(Histone deacetylase class II, yeast)|interpro:IPR019154|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|rcsb pdb:5J8J|reactome:R-SCE-3371511	refseq:NP_010007.1|sgd:S000000680|ensemblfungi:YCR084C(gene)|ensemblfungi:YCR084C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:1900192"(positive regulation of single-species biofilm formation)|go:"GO:2000217"(regulation of invasive growth in response to glucose limitation)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR013890(Transcriptional repressor Tup1,  N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1ERJ|rcsb pdb:3VP8|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:3VP9|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043486"(histone exchange)|dip:DIP-512N|mint:P16649	-	crc64:4E7069E66D03264D	crc64:444104AAD63CB944	figure legend:4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/16	2014/10/16	rogid:8DSf/IhxXMOoChc37MKgkzZzk+o559292	rogid:luwCf4aC9uWc9C8Vt2etbCoLcU8559292	intact-crc:31CFEC4C2A41C060|rigid:ndIXEGZTcbTGL4HI8ySwsO2zMWM	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|binding-associated region:73-386	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q06623	uniprotkb:P16649	intact:EBI-38663|uniprotkb:D6W4H9|ensemblfungi:YPR179C	intact:EBI-19654|uniprotkb:P17995|uniprotkb:P18323|uniprotkb:D6VR85|ensemblfungi:YCR084C	psi-mi:hda3_yeast(display_long)|uniprotkb:Histone deacetylase complex 1 subunit 3(gene name synonym)|uniprotkb:HDA3(gene name)|psi-mi:HDA3(display_short)|uniprotkb:PLO1(gene name synonym)|uniprotkb:YPR179C(locus name)	psi-mi:tup1_yeast(display_long)|uniprotkb:TUP1(gene name)|psi-mi:TUP1(display_short)|uniprotkb:AAR1(gene name synonym)|uniprotkb:AER2(gene name synonym)|uniprotkb:AMM1(gene name synonym)|uniprotkb:CYC9(gene name synonym)|uniprotkb:FLK1(gene name synonym)|uniprotkb:SFL2(gene name synonym)|uniprotkb:UMR7(gene name synonym)|uniprotkb:YCR084C(locus name)|uniprotkb:YCR84C(orf name)|uniprotkb:Glucose repression regulatory protein TUP1(gene name synonym)|uniprotkb:Flocculation suppressor protein(gene name synonym)|uniprotkb:Repressor AER2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wu et al. (2001)	pubmed:11172717|imex:IM-19439	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1370424|imex:IM-19439-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015505.1|sgd:S000006383|mint:Q06623|dip:DIP-4636N|ensemblfungi:YPR179C(gene)|ensemblfungi:YPR179C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0070823"(HDA1 complex)|interpro:IPR021006|interpro:IPR026216|interpro:IPR038609|rcsb pdb:3HGQ|rcsb pdb:3HGT|rcsb pdb:6Z6F|rcsb pdb:6Z6H|rcsb pdb:6Z6O|rcsb pdb:6Z6P	refseq:NP_010007.1|sgd:S000000680|ensemblfungi:YCR084C(gene)|ensemblfungi:YCR084C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:1900192"(positive regulation of single-species biofilm formation)|go:"GO:2000217"(regulation of invasive growth in response to glucose limitation)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR013890(Transcriptional repressor Tup1,  N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1ERJ|rcsb pdb:3VP8|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:3VP9|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043486"(histone exchange)|dip:DIP-512N|mint:P16649	-	-	crc64:444104AAD63CB944	figure legend:4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/16	2014/10/16	rogid:rL/Axy69+g/ApTTWi7uWnItY22w559292	rogid:luwCf4aC9uWc9C8Vt2etbCoLcU8559292	intact-crc:677E67FC8F2CD70D|rigid:Mkbb6maBe5gXFOrk9a3EVrkp7oU	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)