#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P33244 uniprotkb:P02835 intact:EBI-160447|ensemblmetazoa:FBpp0074853|uniprotkb:Q24538|uniprotkb:Q8IQT5|uniprotkb:Q960U2|uniprotkb:Q9VVS8|uniprotkb:B9EQU1 intact:EBI-125786|uniprotkb:O96929|uniprotkb:Q4V6Y3|uniprotkb:Q9V3W3|ensemblmetazoa:FBpp0081139 psi-mi:ftzf1_drome(display_long)|uniprotkb:ftz-f1(gene name)|psi-mi:ftz-f1(display_short)|uniprotkb:NR5A3(gene name synonym)|uniprotkb:CG4059(orf name)|uniprotkb:FTZ-F1 alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 5 group A member 3(gene name synonym) psi-mi:ftz_drome(display_long)|uniprotkb:ftz(gene name)|psi-mi:ftz(display_short)|uniprotkb:CG2047(orf name) psi-mi:"MI:0047"(far western blotting) Schwartz et al. (2001) pubmed:11157757|imex:IM-19731|mint:MINT-5213442 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1396410|imex:IM-19731-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524143.2|refseq:NP_730359.1|flybase:FBgn0001078|ensemblmetazoa:FBgn0001078(gene)|ensemblmetazoa:FBtr0075086(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008219"(cell death)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009888"(tissue development)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0035073"(pupariation)|go:"GO:0035074"(pupation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035626"(juvenile hormone mediated signaling pathway)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016355(Orphan nuclear receptor Fushi-tarazu factor 1)|interpro:IPR035500|rcsb pdb:2XHS|reactome:R-DME-383280|reactome:R-DME-4090294|refseq:NP_001246824.1 refseq:NP_477498.1|flybase:FBgn0001077|ensemblmetazoa:FBgn0001077(gene)|ensemblmetazoa:FBtr0081625(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007417"(central nervous system development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035282"(segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR005567(Fushi tarazu, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1FTZ|rcsb pdb:2XHS|dip:DIP-18500N - - - figure legend:1, 3|comment:Ftz_drome constructs with deletions of 112-118 and 257-265 show decreased interaction suggesting that they are both involved in the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:m/yxQjjm37/IaCCpLPpZFwPPV+c7227 rogid:Kvf67LQf7eGvmUDSnAlxn8/kSwU7227 intact-crc:789852D87D33436D|rigid:ONre2Kh2sJnVzLxIFWeW/jJz6/o false 35s radiolabel:?-? necessary binding region:266-410,1-111,119-256 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P02835 uniprotkb:P33244 intact:EBI-125786|uniprotkb:O96929|uniprotkb:Q4V6Y3|uniprotkb:Q9V3W3|ensemblmetazoa:FBpp0081139 intact:EBI-160447|ensemblmetazoa:FBpp0074853|uniprotkb:Q24538|uniprotkb:Q8IQT5|uniprotkb:Q960U2|uniprotkb:Q9VVS8|uniprotkb:B9EQU1 psi-mi:ftz_drome(display_long)|uniprotkb:ftz(gene name)|psi-mi:ftz(display_short)|uniprotkb:CG2047(orf name) psi-mi:ftzf1_drome(display_long)|uniprotkb:ftz-f1(gene name)|psi-mi:ftz-f1(display_short)|uniprotkb:NR5A3(gene name synonym)|uniprotkb:CG4059(orf name)|uniprotkb:FTZ-F1 alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 5 group A member 3(gene name synonym) psi-mi:"MI:0047"(far western blotting) Schwartz et al. (2001) pubmed:11157757|imex:IM-19731|mint:MINT-5213442 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1396601|imex:IM-19731-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477498.1|flybase:FBgn0001077|ensemblmetazoa:FBgn0001077(gene)|ensemblmetazoa:FBtr0081625(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007417"(central nervous system development)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008354"(germ cell migration)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0035282"(segmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR005567(Fushi tarazu, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|rcsb pdb:1FTZ|rcsb pdb:2XHS|dip:DIP-18500N refseq:NP_524143.2|refseq:NP_730359.1|flybase:FBgn0001078|ensemblmetazoa:FBgn0001078(gene)|ensemblmetazoa:FBtr0075086(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002165"(instar larval or pupal development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007480"(imaginal disc-derived leg morphogenesis)|go:"GO:0007552"(metamorphosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008219"(cell death)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009888"(tissue development)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0035073"(pupariation)|go:"GO:0035074"(pupation)|go:"GO:0035075"(response to ecdysone)|go:"GO:0035626"(juvenile hormone mediated signaling pathway)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016355(Orphan nuclear receptor Fushi-tarazu factor 1)|interpro:IPR035500|rcsb pdb:2XHS|reactome:R-DME-383280|reactome:R-DME-4090294|refseq:NP_001246824.1 - - - figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:Kvf67LQf7eGvmUDSnAlxn8/kSwU7227 rogid:m/yxQjjm37/IaCCpLPpZFwPPV+c7227 intact-crc:419F99D42000A562|rigid:ONre2Kh2sJnVzLxIFWeW/jJz6/o false 35s radiolabel:?-? necessary binding region:834..834-876..876 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)