#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q04149	uniprotkb:P38257	intact:EBI-33508|uniprotkb:D6VT20|ensemblfungi:YDR386W	intact:EBI-21547|uniprotkb:P38259|uniprotkb:Q6B1Z9|uniprotkb:D6VQ99|uniprotkb:Q9URQ2|ensemblfungi:YBR098W	psi-mi:mus81_yeast(display_long)|uniprotkb:MUS81(gene name)|psi-mi:MUS81(display_short)|uniprotkb:SLX3(gene name synonym)|uniprotkb:YDR386W(locus name)|uniprotkb:D9509.6(orf name)|uniprotkb:MMS and UV-sensitive protein 81(gene name synonym)	psi-mi:mms4_yeast(display_long)|uniprotkb:MMS4(gene name)|psi-mi:MMS4(display_short)|uniprotkb:SLX2(gene name synonym)|uniprotkb:YBR0826(orf name)|uniprotkb:YBR0829(orf name)|uniprotkb:YBR100W(orf name)|uniprotkb:YBR098W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mullen et al. (2001)	pubmed:11139495|imex:IM-19771	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1567732|imex:IM-19771-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002794|refseq:NP_010674.3|mint:Q04149|dip:DIP-1009N|ensemblfungi:YDR386W(gene)|ensemblfungi:YDR386W_mRNA(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003677"(DNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048257"(3'-flap endonuclease activity)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0051097"(negative regulation of helicase activity)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR027421|interpro:IPR036388|interpro:IPR042530|reactome:R-SCE-5693568	refseq:NP_009656.2|sgd:S000000302|mint:P38257|dip:DIP-2927N|ensemblfungi:YBR098W(gene)|ensemblfungi:YBR098W_mRNA(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR033310|reactome:R-SCE-5693568	-	crc64:F73FA3856C5F87F1	crc64:3B3918DD3B2E7E0C	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/12	2014/10/16	rogid:4p09mOMXnNcLuspURjjdB4S8Vkc559292	rogid:VhqWYn+gxagoC94RBwdOyQJWU4w559292	intact-crc:7B17D3B550D9FE15|rigid:yuEafuCa5ZNLLfNDJBtIU1jlro4	false	v5 tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q04149	uniprotkb:P38257	intact:EBI-33508|uniprotkb:D6VT20|ensemblfungi:YDR386W	intact:EBI-21547|uniprotkb:P38259|uniprotkb:Q6B1Z9|uniprotkb:D6VQ99|uniprotkb:Q9URQ2|ensemblfungi:YBR098W	psi-mi:mus81_yeast(display_long)|uniprotkb:MUS81(gene name)|psi-mi:MUS81(display_short)|uniprotkb:SLX3(gene name synonym)|uniprotkb:YDR386W(locus name)|uniprotkb:D9509.6(orf name)|uniprotkb:MMS and UV-sensitive protein 81(gene name synonym)	psi-mi:mms4_yeast(display_long)|uniprotkb:MMS4(gene name)|psi-mi:MMS4(display_short)|uniprotkb:SLX2(gene name synonym)|uniprotkb:YBR0826(orf name)|uniprotkb:YBR0829(orf name)|uniprotkb:YBR100W(orf name)|uniprotkb:YBR098W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mullen et al. (2001)	pubmed:11139495|imex:IM-19771	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1567740|imex:IM-19771-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002794|refseq:NP_010674.3|mint:Q04149|dip:DIP-1009N|ensemblfungi:YDR386W(gene)|ensemblfungi:YDR386W_mRNA(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003677"(DNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048257"(3'-flap endonuclease activity)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0051097"(negative regulation of helicase activity)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR027421|interpro:IPR036388|interpro:IPR042530|reactome:R-SCE-5693568	refseq:NP_009656.2|sgd:S000000302|mint:P38257|dip:DIP-2927N|ensemblfungi:YBR098W(gene)|ensemblfungi:YBR098W_mRNA(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0031297"(replication fork processing)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR033310|reactome:R-SCE-5693568	-	crc64:F73FA3856C5F87F1	crc64:3B3918DD3B2E7E0C	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/12	2014/10/16	rogid:4p09mOMXnNcLuspURjjdB4S8Vkc559292	rogid:VhqWYn+gxagoC94RBwdOyQJWU4w559292	intact-crc:5FD851665D02F111|rigid:yuEafuCa5ZNLLfNDJBtIU1jlro4	false	v5 tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32828	uniprotkb:P40072	intact:EBI-8276|uniprotkb:D6VRX6|ensemblfungi:YDL013W	intact:EBI-22661|uniprotkb:D3DM22|ensemblfungi:YER116C	psi-mi:slx5_yeast(display_long)|uniprotkb:SLX5(gene name)|psi-mi:SLX5(display_short)|uniprotkb:YDL013W(locus name)|uniprotkb:D2875(orf name)|uniprotkb:Synthetic lethal of unknown function protein 5(gene name synonym)|uniprotkb:Hexose metabolism-related protein HEX3(gene name synonym)|uniprotkb:HEX3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SLX5(gene name synonym)	psi-mi:slx8_yeast(display_long)|uniprotkb:SLX8(gene name)|psi-mi:SLX8(display_short)|uniprotkb:Synthetic lethal of unknown function protein 8(gene name synonym)|uniprotkb:YER116C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SLX8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mullen et al. (2001)	pubmed:11139495|imex:IM-19771	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1567748|imex:IM-19771-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002171|refseq:NP_010271.3|mint:P32828|dip:DIP-727N|ensemblfungi:YDL013W(gene)|ensemblfungi:YDL013W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032183"(SUMO binding)|go:"GO:0033768"(SUMO-targeted ubiquitin ligase complex)|interpro:IPR038886	refseq:NP_011041.3|sgd:S000000918|dip:DIP-1365N|mint:P40072|ensemblfungi:YER116C(gene)|ensemblfungi:YER116C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000776"(kinetochore)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0033768"(SUMO-targeted ubiquitin ligase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957	-	crc64:75846FEA93A65AE9	crc64:358DB6D137155DC1	figure legend:Fig. 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/12	2014/10/16	rogid:NQGax+d6DCnhNixv46U/S2BbJ+k559292	rogid:koTmyYWk4tUBikxl/yVUsmj+V/4559292	intact-crc:A3AAB1D7F2F9C2A7|rigid:y3sr3GOrBscX57ey427LjlV/b3A	false	v5 tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12098	uniprotkb:P38324	intact:EBI-37788|uniprotkb:D6VYD0|ensemblfungi:YLR135W	intact:EBI-21016|uniprotkb:D6VQM3|ensemblfungi:YBR228W	psi-mi:slx4_yeast(display_long)|uniprotkb:SLX4(gene name)|psi-mi:SLX4(display_short)|uniprotkb:L3140(orf name)|uniprotkb:YLR135W(locus name)|uniprotkb:Synthetic lethal of unknown function protein 4(gene name synonym)	psi-mi:slx1_yeast(display_long)|uniprotkb:YBR228W(locus name)|uniprotkb:YBR1525(orf name)|uniprotkb:SLX1(gene name)|psi-mi:SLX1(display_short)|uniprotkb:Synthetic lethal of unknown function protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mullen et al. (2001)	pubmed:11139495|imex:IM-19771	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1567756|imex:IM-19771-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013236.1|sgd:S000004125|dip:DIP-1771N|mint:Q12098|ensemblfungi:YLR135W(gene)|ensemblfungi:YLR135W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000736"(double-strand break repair via single-strand annealing, removal of nonhomologous ends)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0033557"(Slx1-Slx4 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1905261"(regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR018574|interpro:IPR027784|rcsb pdb:6J0Y	refseq:NP_009787.3|sgd:S000000432|mint:P38324|dip:DIP-1770N|ensemblfungi:YBR228W(gene)|ensemblfungi:YBR228W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0033557"(Slx1-Slx4 complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027520|interpro:IPR035901	-	crc64:52C0FD889C8C5835	crc64:4C676E877FDF7A7A	figure legend:Fig. 9B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/12	2014/10/16	rogid:xZ2m26nVxbdkHGSVQMRnq8yJrck559292	rogid:XZhr65kLUI5VTv1IQak9kc31GvA559292	intact-crc:5A06C8C6970779A4|rigid:yxeIBH/fry989De1Xb3yL+cwrUw	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q12098	uniprotkb:P38324	intact:EBI-37788|uniprotkb:D6VYD0|ensemblfungi:YLR135W	intact:EBI-21016|uniprotkb:D6VQM3|ensemblfungi:YBR228W	psi-mi:slx4_yeast(display_long)|uniprotkb:SLX4(gene name)|psi-mi:SLX4(display_short)|uniprotkb:L3140(orf name)|uniprotkb:YLR135W(locus name)|uniprotkb:Synthetic lethal of unknown function protein 4(gene name synonym)	psi-mi:slx1_yeast(display_long)|uniprotkb:YBR228W(locus name)|uniprotkb:YBR1525(orf name)|uniprotkb:SLX1(gene name)|psi-mi:SLX1(display_short)|uniprotkb:Synthetic lethal of unknown function protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mullen et al. (2001)	pubmed:11139495|imex:IM-19771	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1567764|imex:IM-19771-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013236.1|sgd:S000004125|dip:DIP-1771N|mint:Q12098|ensemblfungi:YLR135W(gene)|ensemblfungi:YLR135W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000736"(double-strand break repair via single-strand annealing, removal of nonhomologous ends)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0033557"(Slx1-Slx4 complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:1905261"(regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR018574|interpro:IPR027784|rcsb pdb:6J0Y	refseq:NP_009787.3|sgd:S000000432|mint:P38324|dip:DIP-1770N|ensemblfungi:YBR228W(gene)|ensemblfungi:YBR228W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0033557"(Slx1-Slx4 complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR027520|interpro:IPR035901	-	crc64:52C0FD889C8C5835	crc64:4C676E877FDF7A7A	figure legend:Fig. 9B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/12	2014/10/16	rogid:xZ2m26nVxbdkHGSVQMRnq8yJrck559292	rogid:XZhr65kLUI5VTv1IQak9kc31GvA559292	intact-crc:839932418385F890|rigid:yxeIBH/fry989De1Xb3yL+cwrUw	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)