#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q02630	uniprotkb:Q99257	intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2	intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9	psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym)	psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Strawn et al. (2001)	pubmed:11104765|mint:MINT-5213280	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1566634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N	ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N	-	crc64:FBAB0B9AEA958213	crc64:6CE55EEC6FA40B40	figure legend:"Fig: 2"|delivery method:Q99257 transformation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/10	2014/10/16	rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292	rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292	intact-crc:B446750C3F64B02D|rigid:LObxllb+yHVftbqbXmrq/m+CObU	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02630	uniprotkb:Q99257	intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2	intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9	psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym)	psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name)	psi-mi:"MI:0096"(pull down)	Strawn et al. (2001)	pubmed:11104765|mint:MINT-5213280	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1566646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N	ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N	-	crc64:FBAB0B9AEA958213	crc64:6CE55EEC6FA40B40	figure legend:"Fig: 3D & 3E"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/12/10	2014/10/16	rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292	rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292	intact-crc:145100F9112ED601|rigid:LObxllb+yHVftbqbXmrq/m+CObU	false	glutathione s tranferase tag:?-?|sufficient binding region:160-730	maltose binding protein tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q02629	uniprotkb:Q99257	intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9	intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9	psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym)	psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name)	psi-mi:"MI:0096"(pull down)	Strawn et al. (2001)	pubmed:11104765|mint:MINT-5213280	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1566656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N	ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N	-	crc64:D3985F9901BBAA51	crc64:6CE55EEC6FA40B40	figure legend:"Fig: 3D"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/12/10	2014/10/16	rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292	rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292	intact-crc:F8C0E174158A84EB|rigid:mj6FalpcqgC60s8xQL1NxGVvkf0	false	sufficient binding region:2-610|glutathione s tranferase tag:?-?	maltose binding protein tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q06142	uniprotkb:Q02629	intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6	intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9	psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym)	psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym)	psi-mi:"MI:0096"(pull down)	Strawn et al. (2001)	pubmed:11104765|mint:MINT-5213280	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1566666	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142	ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N	-	crc64:ED530F5313E75B06	crc64:D3985F9901BBAA51	figure legend:"Fig: 3C"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/12/10	2014/10/16	rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292	rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292	intact-crc:191EF84261E72E7B|rigid:IdzBoP+vCxDiWX/lY+Tihqcr/Nk	false	his tag:?-?	sufficient binding region:2-610|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q06142	uniprotkb:Q02630	intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6	intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2	psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym)	psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym)	psi-mi:"MI:0096"(pull down)	Strawn et al. (2001)	pubmed:11104765|mint:MINT-5213280	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1566676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142	ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N	-	crc64:ED530F5313E75B06	crc64:FBAB0B9AEA958213	figure legend:"Fig: 3C"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/12/10	2014/10/16	rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292	rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292	intact-crc:6BB73CA338A5ED2A|rigid:PsQD1p9YrX32vsSEhtpLf/uXRrw	false	his tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:160-730	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q02630	uniprotkb:Q99257	intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2	intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9	psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym)	psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name)	psi-mi:"MI:0018"(two hybrid)	Strawn et al. (2001)	pubmed:11104765|mint:MINT-5213280	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1566686	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N	ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N	-	crc64:FBAB0B9AEA958213	crc64:6CE55EEC6FA40B40	figure legend:"Fig: 4"|comment:Both 160-162 and 362-535 GLFG regions of NUP116 are sufficient to bind MEX67	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/10	2014/10/16	rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292	rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292	intact-crc:906CF9154D2CA8C5|rigid:LObxllb+yHVftbqbXmrq/m+CObU	false	sufficient binding region:160-362|sufficient binding region:362-535	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06142	uniprotkb:Q02630	intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6	intact:EBI-11703|ensemblfungi:YMR047C|uniprotkb:D6VZM2	psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym)	psi-mi:nu116_yeast(display_long)|uniprotkb:NUP116(gene name)|psi-mi:NUP116(display_short)|uniprotkb:NSP116(gene name synonym)|uniprotkb:YMR047C(locus name)|uniprotkb:YM9532.12C(orf name)|uniprotkb:Nuclear pore protein NUP116/NSP116(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Strawn et al. (2001)	pubmed:11104765|mint:MINT-5213280	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1566699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142	ensemblfungi:YMR047C(gene)|ensemblfungi:YMR047C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0051117"(ATPase binding)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:1O6P|rcsb pdb:2AIV|rcsb pdb:3PBP|go:"GO:0017056"(structural constituent of nuclear pore)|refseq:NP_013762.1|sgd:S000004650|mint:Q02630|dip:DIP-2389N	-	crc64:ED530F5313E75B06	crc64:FBAB0B9AEA958213	figure legend:"Fig: 4"|comment:Both 362-535 and 536-732 GLFG regions of NUP116 are sufficient to bind MEX67	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/10	2014/10/16	rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292	rogid:ZuiHiCdDSP9OqFdd1+fJ07WNe7Y559292	intact-crc:1868BF179FDB0A24|rigid:PsQD1p9YrX32vsSEhtpLf/uXRrw	false	-	sufficient binding region:536-732|sufficient binding region:362-535	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)