#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53141 uniprotkb:P53141 intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40 intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40 psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym) psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Boyne et al. (2000) pubmed:11082046 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1561970 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N - crc64:D7508123C101E4A6 crc64:D7508123C101E4A6 figure legend:Fig. 5A taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/30 2014/10/16 rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292 rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292 intact-crc:1C878E93F14C20EB|rigid:9ER1SIe46hJJjPBIoYgNb4zMMbY false ha tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12280 uniprotkb:P53141 intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40 psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name) psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Boyne et al. (2000) pubmed:11082046 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1561986 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406 ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N - - crc64:D7508123C101E4A6 figure legend:Fig. 5B, 6A & 6B|comment:The interaction occurs even if Myo1 is absent. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/30 2014/10/16 rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292 rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292 intact-crc:3A9F90ED40A26E57|rigid:1Ed0sBJ+vAmJ2Ty6KukvFVFzVZo false ha tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53141 uniprotkb:P08964 intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40 intact:EBI-11650|ensemblfungi:YHR023W|uniprotkb:D3DKX0 psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym) psi-mi:myo1_yeast(display_long)|uniprotkb:MYO1(gene name)|psi-mi:MYO1(display_short)|uniprotkb:Type II myosin(gene name synonym)|uniprotkb:YHR023W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Boyne et al. (2000) pubmed:11082046 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1561995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N ensemblfungi:YHR023W(gene)|ensemblfungi:YHR023W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016460"(myosin II complex)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036961|reactome:R-SCE-5627123|refseq:NP_011888.1|sgd:S000001065|mint:P08964|dip:DIP-808N - crc64:D7508123C101E4A6 crc64:6F54C7611F43DC9F figure legend:Fig. 5C & 6C|comment:The interaction does nor require a functional Iqg1. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/30 2014/10/16 rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292 rogid:Itn/sUB37QxWeXWSpQufNogGAHY559292 intact-crc:FA9F8DC5387CF884|rigid:oW+URzN55sSLic/PFp27ZD8BjxU false glutathione s tranferase tag:n-n myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12280 uniprotkb:P08964 intact:EBI-35351|uniprotkb:D6W3C9|ensemblfungi:YPL242C intact:EBI-11650|ensemblfungi:YHR023W|uniprotkb:D3DKX0 psi-mi:iqg1_yeast(display_long)|uniprotkb:IQG1(gene name)|psi-mi:IQG1(display_short)|uniprotkb:CYK1(gene name synonym)|uniprotkb:IQGAP-related protein 1(gene name synonym)|uniprotkb:Cytokinesis protein 1(gene name synonym)|uniprotkb:YPL242C(locus name) psi-mi:myo1_yeast(display_long)|uniprotkb:MYO1(gene name)|psi-mi:MYO1(display_short)|uniprotkb:Type II myosin(gene name synonym)|uniprotkb:YHR023W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Boyne et al. (2000) pubmed:11082046 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1562004 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015082.1|sgd:S000006163|mint:Q12280|dip:DIP-1144N|ensemblfungi:YPL242C(gene)|ensemblfungi:YPL242C_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007165"(signal transduction)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0072741"(protein localization to cell division site)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120155"(MIH complex)|go:"GO:1903471"(regulation of mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903479"(mitotic actomyosin contractile ring assembly actin filament organization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036872|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013406 ensemblfungi:YHR023W(gene)|ensemblfungi:YHR023W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016460"(myosin II complex)|go:"GO:0031671"(primary cell septum biogenesis)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032033"(myosin II light chain binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1904498"(protein localization to mitotic actomyosin contractile ring)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036961|reactome:R-SCE-5627123|refseq:NP_011888.1|sgd:S000001065|mint:P08964|dip:DIP-808N - - crc64:6F54C7611F43DC9F figure legend:Fig. 6A taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/30 2014/10/16 rogid:Xe3LSR8m2pfYpup/TbfpM+UZjzI559292 rogid:Itn/sUB37QxWeXWSpQufNogGAHY559292 intact-crc:0B64BDD8030A01E7|rigid:xmoznESMdVdwTnHRLf+pnKJv2Tg false ha tag:c-c myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)