#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32114-1 uniprotkb:Q6NZQ4 intact:EBI-1395247 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 psi-mi:p32114-1(display_long)|uniprotkb:Pax2(gene name)|psi-mi:Pax2(display_short)|uniprotkb:Pax-2(gene name synonym) psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1395232(pax2_mouse) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 - - - figure legend:no figure for library screen|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/13 2014/10/16 rogid:G12wgmkQVV9HG+L6RZTseJWpi8g10090 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 intact-crc:AB82883AB72E0DA9|rigid:4X9JNAdQDjNJ23wV4L7OqsJNfAs false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32114-1 uniprotkb:Q6NZQ4 intact:EBI-1395247 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 psi-mi:p32114-1(display_long)|uniprotkb:Pax2(gene name)|psi-mi:Pax2(display_short)|uniprotkb:Pax-2(gene name synonym) psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1395232(pax2_mouse) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 - - - figure legend:1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/13 2014/10/16 rogid:G12wgmkQVV9HG+L6RZTseJWpi8g10090 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 intact-crc:435E330165112FA7|rigid:4X9JNAdQDjNJ23wV4L7OqsJNfAs false binding-associated region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6NZQ4 uniprotkb:P32114-2 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 intact:EBI-1395250 psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:p32114-2(display_long)|uniprotkb:Pax2(gene name)|psi-mi:Pax2(display_short)|uniprotkb:Pax-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 intact:EBI-1395232(pax2_mouse) - - - figure legend:1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/13 2014/10/16 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 rogid:Za9zaZY9p6SJrCA/t0vqjgklxaA10090 intact-crc:6E6FD97E7B89955C|rigid:YM2/+C2fCQwZl81j1ZG9OPdrrw4 false - binding-associated region:197-391 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6NZQ4 uniprotkb:Q00288 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 intact:EBI-1395397|uniprotkb:Q6GU20|uniprotkb:P97342|ensembl:ENSMUSP00000028355 psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:pax8_mouse(display_long)|uniprotkb:Pax8(gene name)|psi-mi:Pax8(display_short)|uniprotkb:Pax-8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 refseq:NP_035170.1|ensembl:ENSMUSG00000026976(gene)|ensembl:ENSMUST00000028355(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001655"(urogenital system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048856"(anatomical structure development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001823"(mesonephros development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071599"(otic vesicle development)|go:"GO:0072050"(S-shaped body morphogenesis)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072278"(metanephric comma-shaped body morphogenesis)|go:"GO:0072284"(metanephric S-shaped body morphogenesis)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000611"(positive regulation of thyroid hormone generation)|go:"GO:2000612"(regulation of thyroid-stimulating hormone secretion)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR022130|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565 - - - figure legend:1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/13 2014/10/16 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 rogid:41aRv6r+djf0uC8katu9eOUnmJs10090 intact-crc:6FBEAF5B2D60691C|rigid:rHUv2tDo4jYXbXoH4AcKStri6J4 false - binding-associated region:207-457 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6NZQ4 uniprotkb:P63015 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 intact:EBI-1395428|uniprotkb:P32117|uniprotkb:P70601|uniprotkb:Q62222|uniprotkb:Q64037|uniprotkb:Q8CEI5|uniprotkb:Q8VDB5|uniprotkb:Q921Q8|uniprotkb:Q3UTV5|ensembl:ENSMUSP00000087878|ensembl:ENSMUSP00000106711|ensembl:ENSMUSP00000106712|ensembl:ENSMUSP00000106716 psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:pax6_mouse(display_long)|uniprotkb:Pax-6(gene name synonym)|uniprotkb:Sey(gene name synonym)|uniprotkb:Pax6(gene name)|psi-mi:Pax6(display_short)|uniprotkb:Oculorhombin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 refseq:NP_038655.1|refseq:NP_001297073.1|refseq:NP_001297074.1|refseq:NP_001297075.1|refseq:NP_001231127.1|refseq:NP_001231129.1|refseq:NP_001231130.1|refseq:NP_001231131.1|dip:DIP-38879N|ensembl:ENSMUSG00000027168(gene)|ensembl:ENSMUST00000090397(transcript)|ensembl:ENSMUST00000111082(transcript)|ensembl:ENSMUST00000111083(transcript)|ensembl:ENSMUST00000111087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003002"(regionalization)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003322"(pancreatic A cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0021543"(pallium development)|go:"GO:0021593"(rhombomere morphogenesis)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021778"(oligodendrocyte cell fate specification)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021905"(forebrain-midbrain boundary formation)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021986"(habenula development)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070094"(positive regulation of glucagon secretion)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0098598"(learned vocalization behavior or vocal learning)|go:"GO:0120008"(positive regulation of glutamatergic neuron differentiation)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904937"(sensory neuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|go:"GO:0003690"(double-stranded DNA binding)|interpro:IPR017970|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P63015|interpro:IPR009057(Homeodomain-like) - - - figure legend:1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/13 2014/10/16 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 rogid:Fy8LCDCQ1ZwGv6PWDz/B/NTackM10090 intact-crc:F622BF89AEF7BA19|rigid:fG/KgJobBtW0C7SOEX4J9N/8O/0 false - binding-associated region:271-422 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32114 uniprotkb:Q6NZQ4 intact:EBI-1395232|uniprotkb:A7E2R6 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 psi-mi:pax2_mouse(display_long)|uniprotkb:Pax2(gene name)|psi-mi:Pax2(display_short)|uniprotkb:Pax-2(gene name synonym) psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035167.4|interpro:IPR009057(Homeodomain-like)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR022130|interpro:IPR043565|interpro:IPR036388|interpro:IPR043182|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002072"(optic cup morphogenesis involved in camera-type eye development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005764"(lysosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0021554"(optic nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031016"(pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035566"(regulation of metanephros size)|go:"GO:0035799"(ureter maturation)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0061360"(optic chiasma development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072172"(mesonephric tubule formation)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072189"(ureter development)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072300"(positive regulation of metanephric glomerulus development)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000597"(positive regulation of optic nerve formation) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 - - - figure legend:5B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2007/09/13 2014/10/16 rogid:G12wgmkQVV9HG+L6RZTseJWpi8g10090 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 intact-crc:2D9D323E1990EE58|rigid:4X9JNAdQDjNJ23wV4L7OqsJNfAs false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6NZQ4 uniprotkb:P32114 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 intact:EBI-1395232|uniprotkb:A7E2R6 psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:pax2_mouse(display_long)|uniprotkb:Pax2(gene name)|psi-mi:Pax2(display_short)|uniprotkb:Pax-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 refseq:NP_035167.4|interpro:IPR009057(Homeodomain-like)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR022130|interpro:IPR043565|interpro:IPR036388|interpro:IPR043182|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002072"(optic cup morphogenesis involved in camera-type eye development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005764"(lysosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0021554"(optic nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031016"(pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035566"(regulation of metanephros size)|go:"GO:0035799"(ureter maturation)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0061360"(optic chiasma development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072172"(mesonephric tubule formation)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072189"(ureter development)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072300"(positive regulation of metanephric glomerulus development)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000597"(positive regulation of optic nerve formation) - - - figure legend:5B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2007/09/13 2014/10/16 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 rogid:G12wgmkQVV9HG+L6RZTseJWpi8g10090 intact-crc:C2FD227FF784044A|rigid:4X9JNAdQDjNJ23wV4L7OqsJNfAs false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6NZQ4 uniprotkb:P32114-2 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 intact:EBI-1395250 psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:p32114-2(display_long)|uniprotkb:Pax2(gene name)|psi-mi:Pax2(display_short)|uniprotkb:Pax-2(gene name synonym) psi-mi:"MI:0096"(pull down) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1395549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 intact:EBI-1395232(pax2_mouse) - - - figure legend:5C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 rogid:Za9zaZY9p6SJrCA/t0vqjgklxaA10090 intact-crc:BBDB5348D9D3620F|rigid:YM2/+C2fCQwZl81j1ZG9OPdrrw4 false 35s radiolabel:?-? sufficient binding region:?-?|glutathione s tranferase tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P32114 uniprotkb:Q6NZQ4 intact:EBI-1395232|uniprotkb:A7E2R6 intact:EBI-1395317|uniprotkb:Q9Z0W6|ensembl:ENSMUSP00000002291 psi-mi:pax2_mouse(display_long)|uniprotkb:Pax2(gene name)|psi-mi:Pax2(display_short)|uniprotkb:Pax-2(gene name synonym) psi-mi:paxi1_mouse(display_long)|uniprotkb:Paxip1(gene name)|psi-mi:Paxip1(display_short)|uniprotkb:Ptip(gene name synonym)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lechner et al. (2000) pubmed:10908331 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1395594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035167.4|interpro:IPR009057(Homeodomain-like)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR022130|interpro:IPR043565|interpro:IPR036388|interpro:IPR043182|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001655"(urogenital system development)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001822"(kidney development)|go:"GO:0001823"(mesonephros development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002072"(optic cup morphogenesis involved in camera-type eye development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005764"(lysosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0021554"(optic nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031016"(pancreas development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035566"(regulation of metanephros size)|go:"GO:0035799"(ureter maturation)|go:"GO:0039003"(pronephric field specification)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048793"(pronephros development)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0061360"(optic chiasma development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072108"(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072172"(mesonephric tubule formation)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072179"(nephric duct formation)|go:"GO:0072189"(ureter development)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072221"(metanephric distal convoluted tubule development)|go:"GO:0072289"(metanephric nephron tubule formation)|go:"GO:0072300"(positive regulation of metanephric glomerulus development)|go:"GO:0072305"(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900212"(negative regulation of mesenchymal cell apoptotic process involved in metanephros development)|go:"GO:1900215"(negative regulation of apoptotic process involved in metanephric collecting duct development)|go:"GO:1900218"(negative regulation of apoptotic process involved in metanephric nephron tubule development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000594"(positive regulation of metanephric DCT cell differentiation)|go:"GO:2000597"(positive regulation of optic nerve formation) refseq:NP_061366.2|ensembl:ENSMUSG00000002221(gene)|ensembl:ENSMUST00000002291(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6NZQ4|reactome:R-MMU-5693571 go:"GO:0005634"(nucleus) - - figure legend:7D and E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2007/09/13 2014/10/16 rogid:G12wgmkQVV9HG+L6RZTseJWpi8g10090 rogid:Zf/0f7XECNVGnewJWFUJi4IYeWA10090 intact-crc:C224407B219257DA|rigid:4X9JNAdQDjNJ23wV4L7OqsJNfAs false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)