#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07091	uniprotkb:P07091	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	intact-crc:68BAE0EDFBF61079|rigid:yx0RY71oQaEfzO/6GrQoU4dI4S4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07091	uniprotkb:P56565	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544186|uniprotkb:O88949	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1547586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	intact-crc:123CF05B6BFBD692|rigid:KKoOXvSZLTPph+QXYnxqBYuocZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P56565	uniprotkb:P07091	intact:EBI-1544186|uniprotkb:O88949	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	-	-	-	figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/10/09	2014/10/16	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	intact-crc:518BF08E4F6F57FE|rigid:KKoOXvSZLTPph+QXYnxqBYuocZQ	false	-	mutation disrupting interaction:72-72|mutation disrupting interaction:76-76,81-81,86-86,93-93|mutation disrupting interaction:76-76,81-81|mutation disrupting interaction:76-76|binding-associated region:79-79	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07091	uniprotkb:P07091	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	-	-	-	figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	intact-crc:C941D13C85A13AD3|rigid:yx0RY71oQaEfzO/6GrQoU4dI4S4	false	-	mutation disrupting interaction:72-72|binding-associated region:79-79	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07091	uniprotkb:P07091	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	-	-	-	figure legend:1 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	intact-crc:4A2CB2987B6BBDA6|rigid:yx0RY71oQaEfzO/6GrQoU4dI4S4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07091	uniprotkb:P56565	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544186|uniprotkb:O88949	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	-	-	-	figure legend:1 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	intact-crc:5E96445031B53AD6|rigid:KKoOXvSZLTPph+QXYnxqBYuocZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07091	uniprotkb:P56565	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544186|uniprotkb:O88949	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	-	-	-	figure legend:1 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	intact-crc:7111F3A082845810|rigid:KKoOXvSZLTPph+QXYnxqBYuocZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56565	uniprotkb:P07091	intact:EBI-1544186|uniprotkb:O88949	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	-	-	-	complex-properties:MW = 24 982.00 Da|figure legend:2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/09	2014/10/16	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	intact-crc:8C42DE94C17D3D97|rigid:KKoOXvSZLTPph+QXYnxqBYuocZQ	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07091	uniprotkb:P07091	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	-	-	-	figure legend:2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	intact-crc:4C8A897E4C18E8FD|rigid:EKnpJWUniw8qumdUW6YQCmn/U8k	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56565	uniprotkb:P56565	intact:EBI-1544186|uniprotkb:O88949	intact:EBI-1544186|uniprotkb:O88949	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	-	-	-	figure legend:2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/09	2014/10/16	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	intact-crc:7A63E35773326CF5|rigid:NL4I5IyIndbGEVMOKVTBvcnEljc	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07091	uniprotkb:P56565	intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046	intact:EBI-1544186|uniprotkb:O88949	psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym)	psi-mi:s10a1_mouse(display_long)|uniprotkb:S100a1(gene name)|psi-mi:S100a1(display_short)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Tarabykina et al. (2000)	pubmed:10869553	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1544336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091	interpro:IPR002048(Calcium-binding EF-hand)|refseq:NP_035439.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|reactome:R-MMU-5686938|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)	-	-	-	figure legend:3|comment:The results indicate that this complex forms in the presence and in the absence of calcium, suggesting that the mechanism of the S100A4/  S100A1 heterodimerization could be di�erent from that of  the homodimerization of S100A4.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/09	2014/10/16	rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090	rogid:Av0aT4P1V8M88hFyBN2n+7toK0A10090	intact-crc:741D928F08B8FCFA|rigid:KKoOXvSZLTPph+QXYnxqBYuocZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)