#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q02792	uniprotkb:P53063	intact:EBI-14845|uniprotkb:D6W2B4|ensemblfungi:YOR048C	intact:EBI-24206|uniprotkb:D6VV89|ensemblfungi:YGL246C	psi-mi:xrn2_yeast(display_long)|uniprotkb:Ribonucleic acid-trafficking protein 1(gene name synonym)|uniprotkb:TAP1(gene name synonym)|uniprotkb:YOR048C(locus name)|uniprotkb:RAT1(gene name)|psi-mi:RAT1(display_short)|uniprotkb:HKE1(gene name synonym)|uniprotkb:p116(gene name synonym)	psi-mi:dxo_yeast(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:RAT1-interacting protein(gene name synonym)|uniprotkb:NRE387(orf name)|uniprotkb:YGL246C(locus name)|uniprotkb:NAD-capped RNA hydrolase RAI1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Xue et al. (2000)	pubmed:10805743|imex:IM-19040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1551805|imex:IM-19040-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014691.1|sgd:S000005574|ensemblfungi:YOR048C(gene)|ensemblfungi:YOR048C_mRNA(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:1901408"(negative regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|dip:DIP-6692N|mint:Q02792	refseq:NP_011268.1|sgd:S000003215|dip:DIP-6807N|mint:P53063|go:"GO:0000166"(nucleotide binding)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034353"(RNA pyrophosphohydrolase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110152"("RNA NAD-cap (NAD-forming) hydrolase activity")|go:"GO:0110155"(NAD-cap decapping)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR013961(RAI1 like)|interpro:IPR039039|ensemblfungi:YGL246C(gene)|ensemblfungi:YGL246C_mRNA(transcript)	-	-	crc64:E4A6565AF690A3E1	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/11/05	2014/10/16	rogid:ru4DvnWw27lSZ0+zI14v/2SOm0E559292	rogid:7xzLm7HzpvFkqYj728WLjFnsUeo559292	intact-crc:47E6865C947BF8BE|rigid:vqGdbQdoH1oesweTI3sRpRmdJsQ	false	-	glutathione s tranferase tag:n-n|necessary binding region:273-287	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53063	intact:EBI-1564117	intact:EBI-24206|uniprotkb:D6VV89|ensemblfungi:YGL246C	-	psi-mi:dxo_yeast(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:RAT1-interacting protein(gene name synonym)|uniprotkb:NRE387(orf name)|uniprotkb:YGL246C(locus name)|uniprotkb:NAD-capped RNA hydrolase RAI1(gene name synonym)	psi-mi:mfa2_yeast_mrna(display_short)|psi-mi:EBI-1564117(display_long)	psi-mi:"MI:0415"(enzymatic study)	Xue et al. (2000)	pubmed:10805743|imex:IM-19040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1551823|imex:IM-19040-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0324"(messenger rna)	refseq:NP_011268.1|sgd:S000003215|dip:DIP-6807N|mint:P53063|go:"GO:0000166"(nucleotide binding)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034353"(RNA pyrophosphohydrolase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110152"("RNA NAD-cap (NAD-forming) hydrolase activity")|go:"GO:0110155"(NAD-cap decapping)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR013961(RAI1 like)|interpro:IPR039039|ensemblfungi:YGL246C(gene)|ensemblfungi:YGL246C_mRNA(transcript)	-	go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)	crc64:E4A6565AF690A3E1	comment:RNA strand derived from in vitro transcription of yeast Mfa2 DNA	figure legend:Fig. 9 & 10|comment:Rai1p stabilizes the exoribonuclease activity of Rat1p in vitro.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/05	2014/10/16	rogid:7xzLm7HzpvFkqYj728WLjFnsUeo559292	-	intact-crc:1B97ED5C2E4FE13F	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53063	uniprotkb:Q02792	intact:EBI-24206|uniprotkb:D6VV89|ensemblfungi:YGL246C	intact:EBI-14845|uniprotkb:D6W2B4|ensemblfungi:YOR048C	psi-mi:dxo_yeast(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:RAT1-interacting protein(gene name synonym)|uniprotkb:NRE387(orf name)|uniprotkb:YGL246C(locus name)|uniprotkb:NAD-capped RNA hydrolase RAI1(gene name synonym)	psi-mi:xrn2_yeast(display_long)|uniprotkb:Ribonucleic acid-trafficking protein 1(gene name synonym)|uniprotkb:TAP1(gene name synonym)|uniprotkb:YOR048C(locus name)|uniprotkb:RAT1(gene name)|psi-mi:RAT1(display_short)|uniprotkb:HKE1(gene name synonym)|uniprotkb:p116(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Xue et al. (2000)	pubmed:10805743|imex:IM-19040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1551823|imex:IM-19040-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011268.1|sgd:S000003215|dip:DIP-6807N|mint:P53063|go:"GO:0000166"(nucleotide binding)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0034353"(RNA pyrophosphohydrolase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0110152"("RNA NAD-cap (NAD-forming) hydrolase activity")|go:"GO:0110155"(NAD-cap decapping)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR013961(RAI1 like)|interpro:IPR039039|ensemblfungi:YGL246C(gene)|ensemblfungi:YGL246C_mRNA(transcript)	refseq:NP_014691.1|sgd:S000005574|ensemblfungi:YOR048C(gene)|ensemblfungi:YOR048C_mRNA(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030846"("termination of RNA polymerase II transcription, poly(A)-coupled")|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:1901408"(negative regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|dip:DIP-6692N|mint:Q02792	go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)	crc64:E4A6565AF690A3E1	-	figure legend:Fig. 9 & 10|comment:Rai1p stabilizes the exoribonuclease activity of Rat1p in vitro.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/05	2014/10/16	rogid:7xzLm7HzpvFkqYj728WLjFnsUeo559292	rogid:ru4DvnWw27lSZ0+zI14v/2SOm0E559292	intact-crc:1B97ED5C2E4FE13F	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)