#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49723 uniprotkb:P09938 intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:"MI:0096"(pull down) Chabes et al. (2000) pubmed:10716984|imex:IM-18882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1396209|imex:IM-18882-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 - crc64:712853F2D87D3972 crc64:DB98028408292042 figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2007/09/14 2014/10/16 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 intact-crc:54A1643A2FF90A8F|rigid:2MJOr+Yhrt/yzj5uIBakQZYZr5A false - his tag:n-n 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P49723 uniprotkb:P09938 intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Chabes et al. (2000) pubmed:10716984|imex:IM-18882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1396310|imex:IM-18882-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 - crc64:712853F2D87D3972 crc64:DB98028408292042 figure legend:Figure 3|comment:H6Rnr2p gains alpha-helical content on complexing with Rnr4p|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2007/09/14 2014/10/16 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 intact-crc:F0D0E4BBD821DAB6|rigid:2MJOr+Yhrt/yzj5uIBakQZYZr5A false - his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09938 uniprotkb:P49723 intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Chabes et al. (2000) pubmed:10716984|imex:IM-18882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1396390|imex:IM-18882-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 - crc64:DB98028408292042 crc64:712853F2D87D3972 figure legend:Figure 4|comment:Sedimentation coefficient = 5.6S|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 intact-crc:02BFD2C9D6778CDC|rigid:2MJOr+Yhrt/yzj5uIBakQZYZr5A false his tag:n-n - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09938 uniprotkb:P09938 intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Chabes et al. (2000) pubmed:10716984|imex:IM-18882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1396403|imex:IM-18882-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 go:"GO:0042803"(protein homodimerization activity) crc64:DB98028408292042 crc64:DB98028408292042 figure legend:Figure 4|comment:Sedimentation coefficient = 5.6S|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 intact-crc:7BB3DD733A02DB98|rigid:3++dhUE2zGoQwIrjzxSF2nsp/qM false his tag:n-n his tag:n-n 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49723 uniprotkb:P49723 intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Chabes et al. (2000) pubmed:10716984|imex:IM-18882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1396533|imex:IM-18882-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 go:"GO:0042803"(protein homodimerization activity) crc64:712853F2D87D3972 crc64:712853F2D87D3972 figure legend:Figure 4|comment:Sedimentation coefficient = 5.6S|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 intact-crc:E2C3324FBFC946B4|rigid:iQlSUf/o/i0C6s5wEa2gHckZrn8 false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21524 uniprotkb:P09938 intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym) psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Chabes et al. (2000) pubmed:10716984|imex:IM-18882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1396608|imex:IM-18882-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524 refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 - crc64:56BE1B077916E419 crc64:DB98028408292042 figure legend:Figure 4|comment:Sedimentation coefficient = 9.7S|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 intact-crc:4ED100281480F588|rigid:F39P36OhALSLdrLx+Y7B0cC6tx4 false - his tag:n-n 2 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21524 uniprotkb:P49723 intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym) psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Chabes et al. (2000) pubmed:10716984|imex:IM-18882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1396608|imex:IM-18882-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524 sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 - crc64:56BE1B077916E419 crc64:712853F2D87D3972 figure legend:Figure 4|comment:Sedimentation coefficient = 9.7S|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 intact-crc:4ED100281480F588|rigid:F39P36OhALSLdrLx+Y7B0cC6tx4 false - - 2 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)