#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32565 uniprotkb:P19812 intact:EBI-15919|uniprotkb:D6VVK9|ensemblfungi:YIL075C intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C psi-mi:rpn2_yeast(display_long)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)|uniprotkb:SEN3(gene name synonym)|uniprotkb:YIL075C(locus name) psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1551934|imex:IM-19171-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012190.1|sgd:S000001337|ensemblfungi:YIL075C(gene)|ensemblfungi:YIL075C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4ADY|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-4638N|mint:P32565 refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N - crc64:881E78EBC6BD934F crc64:33E4CD3A031AF523 figure legend:"Fig: 3A"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:XKuDty+1gX7/pz7ZtNmYK4Pfkc8559292 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 intact-crc:DF2FB81621E5FCF4|rigid:tslvZy49494JrK3gEn32hBUExDc false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P33299 uniprotkb:P19812 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1551942|imex:IM-19171-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N - crc64:8454BBC9D549EC5C crc64:33E4CD3A031AF523 figure legend:"Fig: 3A"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 intact-crc:2CE9637B95A4C05F|rigid:xJg2ZdnJsAlZCY5taxRRNDFzmq8 false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01939 uniprotkb:P19812 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1551950|imex:IM-19171-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N - crc64:9C59E92A0794F60F crc64:33E4CD3A031AF523 figure legend:"Fig: 3A"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 intact-crc:5470C7A13F0DBD1A|rigid:HBbqeTLQjiU7nRcCkYtM8GdsJQg false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P33202 uniprotkb:Q01939 intact:EBI-20010|uniprotkb:D6VXS6|ensemblfungi:YKL010C intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 psi-mi:ufd4_yeast(display_long)|uniprotkb:UFD4(gene name)|psi-mi:UFD4(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase UFD4(gene name synonym)|uniprotkb:YKL162(orf name)|uniprotkb:YKL010C(locus name) psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1551958|imex:IM-19171-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001493|ensemblfungi:YKL010C(gene)|ensemblfungi:YKL010C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR000569(HECT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|reactome:R-SCE-983168|refseq:NP_012915.3|dip:DIP-4873N|mint:P33202 go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N - crc64:A9B8B9D812C6216F crc64:9C59E92A0794F60F figure legend:"Fig: 5A"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:DGctb7Hmu2iOVSFY5RbPxFHrlag559292 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 intact-crc:CD6798DB881C0239|rigid:ZOHEvKK1pIWFflGapRmK1qbzjYY false ha tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32565 uniprotkb:P19812 intact:EBI-15919|uniprotkb:D6VVK9|ensemblfungi:YIL075C intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C psi-mi:rpn2_yeast(display_long)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)|uniprotkb:SEN3(gene name synonym)|uniprotkb:YIL075C(locus name) psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1551975|imex:IM-19171-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012190.1|sgd:S000001337|ensemblfungi:YIL075C(gene)|ensemblfungi:YIL075C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4ADY|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-4638N|mint:P32565 refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N - crc64:881E78EBC6BD934F crc64:33E4CD3A031AF523 figure legend:"Fig: 3B"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:XKuDty+1gX7/pz7ZtNmYK4Pfkc8559292 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 intact-crc:F64B00B42BF5ECCE|rigid:tslvZy49494JrK3gEn32hBUExDc false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P33299 uniprotkb:P19812 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1551983|imex:IM-19171-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N - crc64:8454BBC9D549EC5C crc64:33E4CD3A031AF523 figure legend:"Fig: 3B"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 intact-crc:17A8886A33C7B4FB|rigid:xJg2ZdnJsAlZCY5taxRRNDFzmq8 false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P19812 uniprotkb:Q01939 intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1551991|imex:IM-19171-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N - crc64:33E4CD3A031AF523 crc64:9C59E92A0794F60F figure legend:"Fig: 3B"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 intact-crc:5E6D9545FA7F43AF|rigid:HBbqeTLQjiU7nRcCkYtM8GdsJQg false flag tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01939 uniprotkb:P19812 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552005|imex:IM-19171-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N - crc64:9C59E92A0794F60F crc64:33E4CD3A031AF523 figure legend:"Fig: 3D"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 intact-crc:134989FCA1C3F904|rigid:HBbqeTLQjiU7nRcCkYtM8GdsJQg false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P19812 uniprotkb:Q01939 intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552013|imex:IM-19171-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N - crc64:33E4CD3A031AF523 crc64:9C59E92A0794F60F figure legend:"Fig: 3C"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 intact-crc:0AB668A195E4ED83|rigid:HBbqeTLQjiU7nRcCkYtM8GdsJQg false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40303 uniprotkb:P19812 intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229 intact:EBI-19909|uniprotkb:D6VUW7|ensemblfungi:YGR184C psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym) psi-mi:ubr1_yeast(display_long)|uniprotkb:UBR1(gene name)|psi-mi:UBR1(display_short)|uniprotkb:PTR1(gene name synonym)|uniprotkb:N-recognin-1(gene name synonym)|uniprotkb:N-end-recognizing protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR1(gene name synonym)|uniprotkb:G7168(orf name)|uniprotkb:YGR184C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552021|imex:IM-19171-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N refseq:NP_011700.1|sgd:S000003416|ensemblfungi:YGR184C(gene)|ensemblfungi:YGR184C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090089"(regulation of dipeptide transport)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|go:"GO:1990303"(UBR1-RAD6 ubiquitin ligase complex)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046|rcsb pdb:3NIH|rcsb pdb:3NII|rcsb pdb:3NIJ|rcsb pdb:3NIK|rcsb pdb:3NIL|rcsb pdb:3NIM|rcsb pdb:3NIN|rcsb pdb:3NIS|rcsb pdb:3NIT|rcsb pdb:6KGI|reactome:R-SCE-983168|dip:DIP-2517N - crc64:73AEE63B836E618A crc64:33E4CD3A031AF523 figure legend:"Fig: 3E"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292 rogid:69qKUBXWC7PgeCBsLl6sXu6rEDQ559292 intact-crc:B9A2A598EBEF1139|rigid:bJBegsmYWJAYDBnH97LRa4qJWJA false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01939 uniprotkb:P33202 intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 intact:EBI-20010|uniprotkb:D6VXS6|ensemblfungi:YKL010C psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:ufd4_yeast(display_long)|uniprotkb:UFD4(gene name)|psi-mi:UFD4(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase UFD4(gene name synonym)|uniprotkb:YKL162(orf name)|uniprotkb:YKL010C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552029|imex:IM-19171-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N sgd:S000001493|ensemblfungi:YKL010C(gene)|ensemblfungi:YKL010C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR000569(HECT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|reactome:R-SCE-983168|refseq:NP_012915.3|dip:DIP-4873N|mint:P33202 - crc64:9C59E92A0794F60F crc64:A9B8B9D812C6216F figure legend:"Fig: 5B"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rogid:DGctb7Hmu2iOVSFY5RbPxFHrlag559292 intact-crc:3969D42AD56AFE88|rigid:ZOHEvKK1pIWFflGapRmK1qbzjYY false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38764 uniprotkb:P33202 intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C intact:EBI-20010|uniprotkb:D6VXS6|ensemblfungi:YKL010C psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:ufd4_yeast(display_long)|uniprotkb:UFD4(gene name)|psi-mi:UFD4(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase UFD4(gene name synonym)|uniprotkb:YKL162(orf name)|uniprotkb:YKL010C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552037|imex:IM-19171-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 sgd:S000001493|ensemblfungi:YKL010C(gene)|ensemblfungi:YKL010C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR000569(HECT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|reactome:R-SCE-983168|refseq:NP_012915.3|dip:DIP-4873N|mint:P33202 - crc64:B77954F4A998BA7C crc64:A9B8B9D812C6216F figure legend:"Fig: 5C"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 rogid:DGctb7Hmu2iOVSFY5RbPxFHrlag559292 intact-crc:A0391E8FBE0F8A5A|rigid:EFvK5x1rH2M5qmggCf9cwL8b16g false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38886 uniprotkb:P38764 intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9 intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name) psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552076|imex:IM-19171-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886 refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 - crc64:8A05198B0CD7C0C3 crc64:B77954F4A998BA7C figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 intact-crc:8CEEFA8BD5FBB168|rigid:ZZVbSTp6vSG4NthmqC4K+4FnraY false glutathione s tranferase tag:n-n flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P33299 uniprotkb:P38764 intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552102|imex:IM-19171-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 - crc64:8454BBC9D549EC5C crc64:B77954F4A998BA7C figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 intact-crc:3382F1ACCB868BD3|rigid:IctTINCRjGZ3Y9UudyIR3e9l0lc false glutathione s tranferase tag:n-n flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38764 uniprotkb:Q01939 intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552112|imex:IM-19171-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N - crc64:B77954F4A998BA7C crc64:9C59E92A0794F60F figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 intact-crc:448CECA4574B6F94|rigid:1UkFPtRKQ27gv48ESX+yxO1sldw false flag tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38886 uniprotkb:P38764 intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9 intact:EBI-15913|uniprotkb:D3DKX4|ensemblfungi:YHR027C psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name) psi-mi:rpn1_yeast(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:HRD2(gene name synonym)|uniprotkb:NAS1(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 1(gene name synonym)|uniprotkb:HMG-CoA reductase degradation protein 2(gene name synonym)|uniprotkb:YHR027C(locus name) psi-mi:"MI:0096"(pull down) Xie et al. (2000) pubmed:10688918|imex:IM-19171 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552131|imex:IM-19171-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886 refseq:NP_011892.1|sgd:S000001069|ensemblfungi:YHR027C(gene)|ensemblfungi:YHR027C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|rcsb pdb:2N3T|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBW|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:6FVU|reactome:R-SCE-983168|rcsb pdb:6FVV|rcsb pdb:6FVW|dip:DIP-2876N|mint:P38764 - crc64:8A05198B0CD7C0C3 crc64:B77954F4A998BA7C figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/06 2014/10/16 rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292 rogid:KZvwC6NNLC/jEW8wXPq2z+EFukY559292 intact-crc:EFF74E9B499F668F|rigid:ZZVbSTp6vSG4NthmqC4K+4FnraY false flag tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)