#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P40957	uniprotkb:P40958	intact:EBI-10354|ensemblfungi:YGL086W|uniprotkb:D6VU58	intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2	psi-mi:mad1_yeast(display_long)|uniprotkb:MAD1(gene name)|psi-mi:MAD1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:YGL086W(locus name)	psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chen et al. (1999)	pubmed:10436016|imex:IM-19543	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1268751|imex:IM-19543-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003054|ensemblfungi:YGL086W(gene)|ensemblfungi:YGL086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_011429.3|dip:DIP-293N|mint:P40957	sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958	-	-	-	figure legend:Figure 3A, 4A, 8A|comment:Interaction was shown to be independent of cell cycle or phosphorylation state of Mad1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/06/27	2014/10/16	rogid:KN5bSe+qhWpvc7W6Sh2IolgtLXE559292	rogid:0pxFckODTcklkGn+JcczltjSHRU559292	intact-crc:8E7DEC56E264B7D7|rigid:OYgA+qPyXi3cDIZYT/eC74NcKfg	false	necessary binding region:191-196	necessary binding region:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40957	uniprotkb:P40958	intact:EBI-10354|ensemblfungi:YGL086W|uniprotkb:D6VU58	intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2	psi-mi:mad1_yeast(display_long)|uniprotkb:MAD1(gene name)|psi-mi:MAD1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:YGL086W(locus name)	psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Chen et al. (1999)	pubmed:10436016|imex:IM-19543	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1268845|imex:IM-19543-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003054|ensemblfungi:YGL086W(gene)|ensemblfungi:YGL086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_011429.3|dip:DIP-293N|mint:P40957	sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958	-	-	-	figure legend:Figure 3B|complex-properties:MW = greater than 670 kDa.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/06/27	2014/10/16	rogid:KN5bSe+qhWpvc7W6Sh2IolgtLXE559292	rogid:0pxFckODTcklkGn+JcczltjSHRU559292	intact-crc:B8F80306900C162D|rigid:OYgA+qPyXi3cDIZYT/eC74NcKfg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40957	uniprotkb:P40958	intact:EBI-10354|ensemblfungi:YGL086W|uniprotkb:D6VU58	intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2	psi-mi:mad1_yeast(display_long)|uniprotkb:MAD1(gene name)|psi-mi:MAD1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:YGL086W(locus name)	psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chen et al. (1999)	pubmed:10436016|imex:IM-19543	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1268904|imex:IM-19543-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003054|ensemblfungi:YGL086W(gene)|ensemblfungi:YGL086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_011429.3|dip:DIP-293N|mint:P40957	sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958	-	-	-	figure legend:Figure 6|comment:Interaction was shown to be independent of the phosphorylation state of Mad1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2007/06/27	2014/10/16	rogid:KN5bSe+qhWpvc7W6Sh2IolgtLXE559292	rogid:0pxFckODTcklkGn+JcczltjSHRU559292	intact-crc:7AC0B87A0D0D2DDB|rigid:OYgA+qPyXi3cDIZYT/eC74NcKfg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40957	uniprotkb:P40958	intact:EBI-10354|ensemblfungi:YGL086W|uniprotkb:D6VU58	intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2	psi-mi:mad1_yeast(display_long)|uniprotkb:MAD1(gene name)|psi-mi:MAD1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:YGL086W(locus name)	psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (1999)	pubmed:10436016|imex:IM-19543	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1268930|imex:IM-19543-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003054|ensemblfungi:YGL086W(gene)|ensemblfungi:YGL086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_011429.3|dip:DIP-293N|mint:P40957	sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958	-	-	-	figure legend:Figure 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/06/27	2014/10/16	rogid:KN5bSe+qhWpvc7W6Sh2IolgtLXE559292	rogid:0pxFckODTcklkGn+JcczltjSHRU559292	intact-crc:B0E3339C254E110E|rigid:OYgA+qPyXi3cDIZYT/eC74NcKfg	false	ha tag:?-?|tag:?-?|necessary binding region:714-749	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)