#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8T4F7 uniprotkb:P25843 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 intact:EBI-156199|uniprotkb:Q3YMV6|uniprotkb:Q9VMJ9|ensemblmetazoa:FBpp0078864|ensemblmetazoa:FBpp0078865|ensemblmetazoa:FBpp0078866|ensemblmetazoa:FBpp0089196|ensemblmetazoa:FBpp0301151|ensemblmetazoa:FBpp0301152 psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:prof_drome(display_long)|uniprotkb:chic(gene name)|psi-mi:chic(display_short)|uniprotkb:chi(gene name synonym)|uniprotkb:CG9553(orf name)|uniprotkb:Protein chickadee(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-871938|imex:IM-19735-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) refseq:NP_001245905.1|refseq:NP_001245906.1|go:"GO:0043005"(neuron projection)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|refseq:NP_477016.1|refseq:NP_599131.1|refseq:NP_723136.1|refseq:NP_995635.1|flybase:FBgn0000308|ensemblmetazoa:FBgn0000308(gene)|ensemblmetazoa:FBtr0079233(transcript)|ensemblmetazoa:FBtr0079234(transcript)|ensemblmetazoa:FBtr0079235(transcript)|ensemblmetazoa:FBtr0079236(transcript)|ensemblmetazoa:FBtr0309212(transcript)|ensemblmetazoa:FBtr0309213(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007391"(dorsal closure)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042989"(sequestering of actin monomers)|dip:DIP-22165N - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/14 2014/10/16 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 rogid:ixw/iYa5+5l7H5opccmsaYQvuY87227 intact-crc:9B418B3DF9285D3E|rigid:QAKkRiO8havrn37q5E7EgwZAo7A false sufficient binding region:592-835 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8T4F7 uniprotkb:P25843 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 intact:EBI-156199|uniprotkb:Q3YMV6|uniprotkb:Q9VMJ9|ensemblmetazoa:FBpp0078864|ensemblmetazoa:FBpp0078865|ensemblmetazoa:FBpp0078866|ensemblmetazoa:FBpp0089196|ensemblmetazoa:FBpp0301151|ensemblmetazoa:FBpp0301152 psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:prof_drome(display_long)|uniprotkb:chic(gene name)|psi-mi:chic(display_short)|uniprotkb:chi(gene name synonym)|uniprotkb:CG9553(orf name)|uniprotkb:Protein chickadee(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397069|imex:IM-19735-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) refseq:NP_001245905.1|refseq:NP_001245906.1|go:"GO:0043005"(neuron projection)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|refseq:NP_477016.1|refseq:NP_599131.1|refseq:NP_723136.1|refseq:NP_995635.1|flybase:FBgn0000308|ensemblmetazoa:FBgn0000308(gene)|ensemblmetazoa:FBtr0079233(transcript)|ensemblmetazoa:FBtr0079234(transcript)|ensemblmetazoa:FBtr0079235(transcript)|ensemblmetazoa:FBtr0079236(transcript)|ensemblmetazoa:FBtr0309212(transcript)|ensemblmetazoa:FBtr0309213(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007391"(dorsal closure)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042989"(sequestering of actin monomers)|dip:DIP-22165N - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/09/14 2014/10/16 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 rogid:ixw/iYa5+5l7H5opccmsaYQvuY87227 intact-crc:ECB1927A62E2D06F|rigid:QAKkRiO8havrn37q5E7EgwZAo7A false sufficient binding region:591-641 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25843 uniprotkb:Q8T4F7 intact:EBI-156199|uniprotkb:Q3YMV6|uniprotkb:Q9VMJ9|ensemblmetazoa:FBpp0078864|ensemblmetazoa:FBpp0078865|ensemblmetazoa:FBpp0078866|ensemblmetazoa:FBpp0089196|ensemblmetazoa:FBpp0301151|ensemblmetazoa:FBpp0301152 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 psi-mi:prof_drome(display_long)|uniprotkb:chic(gene name)|psi-mi:chic(display_short)|uniprotkb:chi(gene name synonym)|uniprotkb:CG9553(orf name)|uniprotkb:Protein chickadee(gene name synonym) psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:"MI:0096"(pull down) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397115|imex:IM-19735-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245905.1|refseq:NP_001245906.1|go:"GO:0043005"(neuron projection)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR036140|refseq:NP_477016.1|refseq:NP_599131.1|refseq:NP_723136.1|refseq:NP_995635.1|flybase:FBgn0000308|ensemblmetazoa:FBgn0000308(gene)|ensemblmetazoa:FBtr0079233(transcript)|ensemblmetazoa:FBtr0079234(transcript)|ensemblmetazoa:FBtr0079235(transcript)|ensemblmetazoa:FBtr0079236(transcript)|ensemblmetazoa:FBtr0309212(transcript)|ensemblmetazoa:FBtr0309213(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007300"(ovarian nurse cell to oocyte transport)|go:"GO:0007391"(dorsal closure)|go:"GO:0007420"(brain development)|go:"GO:0007436"(larval salivary gland morphogenesis)|go:"GO:0007488"(histoblast morphogenesis)|go:"GO:0016322"(neuron remodeling)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035193"(larval central nervous system remodeling)|go:"GO:0036098"(male germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042989"(sequestering of actin monomers)|dip:DIP-22165N refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:ixw/iYa5+5l7H5opccmsaYQvuY87227 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 intact-crc:1287A9B6BE14184A|rigid:QAKkRiO8havrn37q5E7EgwZAo7A false - glutathione s tranferase tag:?-?|sufficient binding region:525-835 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P00522 uniprotkb:Q8T4F7 intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym) psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:"MI:0096"(pull down) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1534465|imex:IM-19735-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization) refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 intact-crc:A7CBA4804EFC7958|rigid:76buOTo56l4eEoVVkX3DGrYq7Vo false glutathione s tranferase tag:?-?|sufficient binding region:82-325(IPR001452) sufficient binding region:591-835 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q08012 uniprotkb:Q8T4F7 intact:EBI-161391|uniprotkb:Q0E989|uniprotkb:Q9V6Q5|uniprotkb:A4UZF9|ensemblmetazoa:FBpp0086813|ensemblmetazoa:FBpp0086814|ensemblmetazoa:FBpp0086815|ensemblmetazoa:FBpp0086816|ensemblmetazoa:FBpp0086817 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 psi-mi:grap_drome(display_long)|uniprotkb:drk(gene name)|psi-mi:drk(display_short)|uniprotkb:"E(sev)2B"(gene name synonym)|uniprotkb:Downstream of receptor kinase(gene name synonym)|uniprotkb:Grb2(gene name synonym)|uniprotkb:Protein enhancer of sevenless 2B(gene name synonym)|uniprotkb:CG6033(orf name) psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:"MI:0096"(pull down) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1534821|imex:IM-19735-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476858.1|refseq:NP_725302.1|refseq:NP_725303.1|refseq:NP_725304.1|refseq:NP_725306.1|flybase:FBgn0004638|ensemblmetazoa:FBgn0004638(gene)|ensemblmetazoa:FBtr0087694(transcript)|ensemblmetazoa:FBtr0087695(transcript)|ensemblmetazoa:FBtr0087696(transcript)|ensemblmetazoa:FBtr0087697(transcript)|ensemblmetazoa:FBtr0087698(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005118"(sevenless binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007614"(short-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR030219|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2A36|go:"GO:0008306"(associative learning)|rcsb pdb:2A37|rcsb pdb:2AZS|rcsb pdb:2AZV|reactome:R-DME-109704|reactome:R-DME-112412|reactome:R-DME-1250347|reactome:R-DME-1257604|reactome:R-DME-1295596|reactome:R-DME-1433557|reactome:R-DME-1433559|reactome:R-DME-167044|reactome:R-DME-179812|reactome:R-DME-180292|reactome:R-DME-180336|reactome:R-DME-182971|reactome:R-DME-186763|reactome:R-DME-1963640|reactome:R-DME-1963642|reactome:R-DME-210993|reactome:R-DME-2179392|reactome:R-DME-2424491|reactome:R-DME-2428933|reactome:R-DME-2730905|reactome:R-DME-2871796|reactome:R-DME-2871809|reactome:R-DME-375165|reactome:R-DME-5654688|go:"GO:0008355"(olfactory learning)|reactome:R-DME-5654689|reactome:R-DME-5654693|reactome:R-DME-5654695|reactome:R-DME-5654699|reactome:R-DME-5654700|reactome:R-DME-5654704|reactome:R-DME-5654706|reactome:R-DME-5654710|reactome:R-DME-5654712|reactome:R-DME-5654719|reactome:R-DME-5654720|reactome:R-DME-5654726|reactome:R-DME-5654727|reactome:R-DME-5654732|reactome:R-DME-5673001|reactome:R-DME-6811558|reactome:R-DME-74749|reactome:R-DME-74751|reactome:R-DME-8856825|reactome:R-DME-8856828|reactome:R-DME-9027284|reactome:R-DME-912631|reactome:R-DME-9607240|reactome:R-DME-983695|reactome:R-DME-5654733|dip:DIP-21223N refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:GNPfKX2LH0HRXEW4ASFDTrXN3VY7227 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 intact-crc:8F80A8BBEB097CEA|rigid:St8Pv3LlnaWC72jYjeBXIstEfTg false glutathione s tranferase tag:?-?|sufficient binding region:152..152-211..211(IPR001452) sufficient binding region:591-835 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05480 uniprotkb:Q8T4F7 intact:EBI-298680|ensembl:ENSMUSP00000029175|ensembl:ENSMUSP00000105157|ensembl:ENSMUSP00000105159|uniprotkb:Q2M4I4|intact:EBI-7361449|intact:MINT-142018|uniprotkb:F8WI90 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 psi-mi:src_mouse(display_long)|uniprotkb:Src(gene name)|psi-mi:Src(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym) psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:"MI:0096"(pull down) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1556974|imex:IM-19735-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P05480|rcsb pdb:6F3F|reactome:R-MMU-1227986|reactome:R-MMU-1251985|reactome:R-MMU-1253288|reactome:R-MMU-1257604|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-177929|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-191650|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418885|reactome:R-MMU-430116|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-456926|reactome:R-MMU-5218921|reactome:R-MMU-5607764|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-6811558|reactome:R-MMU-69231|reactome:R-MMU-8853659|reactome:R-MMU-8874081|reactome:R-MMU-8934903|reactome:R-MMU-8941858|reactome:R-MMU-9009391|reactome:R-MMU-9603381|ensembl:ENSMUSG00000027646(gene)|ensembl:ENSMUST00000029175(transcript)|ensembl:ENSMUST00000109531(transcript)|ensembl:ENSMUST00000109533(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|refseq:NP_001020566.1|refseq:NP_033297.2|dip:DIP-31071N refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2021/02/11 rogid:SY8bQUpE/ni7hRMp4F02ygRsU7Q10090 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 intact-crc:F028687AC26CB0DB|rigid:X8pY4TPS2OZblQGUYSIJqr+L6ug false glutathione s tranferase tag:?-?|sufficient binding region:83..83-150..150(IPR001452) sufficient binding region:591-835 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8T4F7 uniprotkb:P00522 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523 psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym) psi-mi:"MI:0096"(pull down) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1534862|imex:IM-19735-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization) - - - figure legend:5|comment:Abl-Pro-AEPPPYPPPPIPGGK, Src-Pro-AERSSRPLPPIPGGK act as competitors for the interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2014/10/16 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227 intact-crc:57CA7C6F4A89B35D|rigid:76buOTo56l4eEoVVkX3DGrYq7Vo false mutation decreasing interaction:763-763,770-772|mutation decreasing interaction:707-709,701-701 sufficient binding region:82-325|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8T4F7 uniprotkb:P05480 intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115 intact:EBI-298680|ensembl:ENSMUSP00000029175|ensembl:ENSMUSP00000105157|ensembl:ENSMUSP00000105159|uniprotkb:Q2M4I4|intact:EBI-7361449|intact:MINT-142018|uniprotkb:F8WI90 psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym) psi-mi:src_mouse(display_long)|uniprotkb:Src(gene name)|psi-mi:Src(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym) psi-mi:"MI:0096"(pull down) Ahern-Djamali et al. (1999) pubmed:10220404|imex:IM-19735 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1557002|imex:IM-19735-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization) go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P05480|rcsb pdb:6F3F|reactome:R-MMU-1227986|reactome:R-MMU-1251985|reactome:R-MMU-1253288|reactome:R-MMU-1257604|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-177929|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-191650|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418885|reactome:R-MMU-430116|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-456926|reactome:R-MMU-5218921|reactome:R-MMU-5607764|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-6811558|reactome:R-MMU-69231|reactome:R-MMU-8853659|reactome:R-MMU-8874081|reactome:R-MMU-8934903|reactome:R-MMU-8941858|reactome:R-MMU-9009391|reactome:R-MMU-9603381|ensembl:ENSMUSG00000027646(gene)|ensembl:ENSMUST00000029175(transcript)|ensembl:ENSMUST00000109531(transcript)|ensembl:ENSMUST00000109533(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|refseq:NP_001020566.1|refseq:NP_033297.2|dip:DIP-31071N - - - figure legend:5|comment:Abl-Pro-AEPPPYPPPPIPGGK, Src-Pro-AERSSRPLPPIPGGK act as competitors for the interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/14 2021/02/11 rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227 rogid:SY8bQUpE/ni7hRMp4F02ygRsU7Q10090 intact-crc:84D8153F88E61A00|rigid:X8pY4TPS2OZblQGUYSIJqr+L6ug false mutation decreasing interaction:701-701,707-709|mutation decreasing interaction:763-763,770-772 glutathione s tranferase tag:?-?|sufficient binding region:83-150(IPR001452) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)