#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P16621	uniprotkb:P00522	intact:EBI-668630|uniprotkb:Q960M3|uniprotkb:Q9VIS8|ensemblmetazoa:FBpp0080801	intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523	psi-mi:lar_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:dLAR(gene name synonym)|uniprotkb:Lar(gene name)|psi-mi:Lar(display_short)|uniprotkb:CG10443(orf name)	psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532874|imex:IM-19333-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523604.2|flybase:FBgn0000464|dip:DIP-38648N|ensemblmetazoa:FBgn0000464(gene)|ensemblmetazoa:FBtr0081260(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007412"(axon target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0045467"(R7 cell development)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0120034"(positive regulation of plasma membrane bounded cell projection assembly)|go:"GO:1903386"(negative regulation of homophilic cell adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2YD1|rcsb pdb:3PXJ|rcsb pdb:6X38|reactome:R-DME-388844|reactome:R-DME-8849932	go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)	-	-	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:rFF+oNmRMa0r6iVk4/gea7ozJfE7227	rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227	intact-crc:8010E323736558D3|rigid:XZnoIcIV5XN+Rh0GF8lIg/xh3S4	false	glutathione s tranferase tag:?-?|sufficient binding region:1451-2029	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8T4F7	uniprotkb:P16621	intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115	intact:EBI-668630|uniprotkb:Q960M3|uniprotkb:Q9VIS8|ensemblmetazoa:FBpp0080801	psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym)	psi-mi:lar_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:dLAR(gene name synonym)|uniprotkb:Lar(gene name)|psi-mi:Lar(display_short)|uniprotkb:CG10443(orf name)	psi-mi:"MI:0096"(pull down)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533733|imex:IM-19333-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization)	refseq:NP_523604.2|flybase:FBgn0000464|dip:DIP-38648N|ensemblmetazoa:FBgn0000464(gene)|ensemblmetazoa:FBtr0081260(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007412"(axon target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0045467"(R7 cell development)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0120034"(positive regulation of plasma membrane bounded cell projection assembly)|go:"GO:1903386"(negative regulation of homophilic cell adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2YD1|rcsb pdb:3PXJ|rcsb pdb:6X38|reactome:R-DME-388844|reactome:R-DME-8849932	-	-	-	figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227	rogid:rFF+oNmRMa0r6iVk4/gea7ozJfE7227	intact-crc:4FA6177BC42502D7|rigid:Od9hgNVSQy49RrvCnFM17roZu8M	false	-	glutathione s tranferase tag:?-?|sufficient binding region:1737-2029	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35992	uniprotkb:Q8T4F7	intact:EBI-675831|uniprotkb:A4V4B4|uniprotkb:Q0KHT5|uniprotkb:Q86NN9|uniprotkb:Q8IR87|uniprotkb:Q9VYW1|uniprotkb:B7Z142|uniprotkb:F0JAM3|uniprotkb:M9PEB6|uniprotkb:M9PJI5|intact:EBI-675858|ensemblmetazoa:FBpp0303418|ensemblmetazoa:FBpp0303419	intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115	psi-mi:ptp10_drome(display_long)|uniprotkb:Receptor-linked protein-tyrosine phosphatase 10D(gene name synonym)|uniprotkb:Ptp10D(gene name)|psi-mi:Ptp10D(display_short)|uniprotkb:CG1817(orf name)	psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1558147|imex:IM-19333-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_996413.2|refseq:NP_996414.2|refseq:NP_001138187.1|refseq:NP_727544.2|flybase:FBgn0004370|refseq:NP_001259453.1|refseq:NP_001259454.1|ensemblmetazoa:FBgn0004370(gene)|ensemblmetazoa:FBtr0330392(transcript)|ensemblmetazoa:FBtr0330393(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007411"(axon guidance)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007616"(long-term memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045177"(apical part of cell)|go:"GO:0060446"(branching involved in open tracheal system development)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|rcsb pdb:3S3E|rcsb pdb:3S3F|rcsb pdb:3S3H|rcsb pdb:3S3K|reactome:R-DME-6798695|go:"GO:0007417"(central nervous system development)	refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization)	-	-	-	figure legend:5|comment:Weak interaction was observed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2015/01/16	rogid:H4TeAMfu/3+wXdDaclgyUv2rLTk7227	rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227	intact-crc:B3F1434D8CFFF501|rigid:YrFDOebmBKcP/K1EPm8DzM7MKyI	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8T4F7	uniprotkb:P16620	intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115	intact:EBI-676392|uniprotkb:Q8IGY3|uniprotkb:Q9VU03|ensemblmetazoa:FBpp0075645	psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym)	psi-mi:ptp69_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:Ptp69D(gene name)|psi-mi:Ptp69D(display_short)|uniprotkb:DPTP(gene name synonym)|uniprotkb:CG10975(orf name)	psi-mi:"MI:0096"(pull down)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1558156|imex:IM-19333-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization)	refseq:NP_524048.2|refseq:NP_788502.1|flybase:FBgn0014007|ensemblmetazoa:FBgn0014007(gene)|ensemblmetazoa:FBtr0075913(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007415"(defasciculation of motor neuron axon)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0030424"(axon)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0097155"(fasciculation of sensory neuron axon)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:P16620	-	-	-	figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227	rogid:YOMEA3aIvtEsQt1qTG+BVCReyuE7227	intact-crc:D3BDDADB14EE2119|rigid:XdTztccwKyAQjreromuA2V8PcHg	false	-	glutathione s tranferase tag:?-?|sufficient binding region:1187..1187-1450..1450	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00522	uniprotkb:P16621	intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523	intact:EBI-668630|uniprotkb:Q960M3|uniprotkb:Q9VIS8|ensemblmetazoa:FBpp0080801	psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym)	psi-mi:lar_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:dLAR(gene name synonym)|uniprotkb:Lar(gene name)|psi-mi:Lar(display_short)|uniprotkb:CG10443(orf name)	psi-mi:"MI:0096"(pull down)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532946|imex:IM-19333-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)	refseq:NP_523604.2|flybase:FBgn0000464|dip:DIP-38648N|ensemblmetazoa:FBgn0000464(gene)|ensemblmetazoa:FBtr0081260(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007412"(axon target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0045467"(R7 cell development)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0120034"(positive regulation of plasma membrane bounded cell projection assembly)|go:"GO:1903386"(negative regulation of homophilic cell adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2YD1|rcsb pdb:3PXJ|rcsb pdb:6X38|reactome:R-DME-388844|reactome:R-DME-8849932	-	-	-	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227	rogid:rFF+oNmRMa0r6iVk4/gea7ozJfE7227	intact-crc:98E8888A1647D24C|rigid:XZnoIcIV5XN+Rh0GF8lIg/xh3S4	false	32p radiolabel:?-?|his tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:1737-2029	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:Q9VAW5	uniprotkb:Q8T4F7	intact:EBI-123668|uniprotkb:Q8IMM4|uniprotkb:Q8MSZ4|uniprotkb:Q8MYR3|uniprotkb:Q9NHN6|uniprotkb:E1JJ02|uniprotkb:A4V3J4|intact:EBI-3420247|intact:EBI-9927516|intact:EBI-9936654|intact:EBI-3436145|intact:EBI-3426670|uniprotkb:D0IQE9|uniprotkb:Q9VAW4|ensemblmetazoa:FBpp0290398|ensemblmetazoa:FBpp0297481|ensemblmetazoa:FBpp0297482	intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115	psi-mi:larp_drome(display_long)|uniprotkb:larp(gene name)|psi-mi:larp(display_short)|uniprotkb:dLarp(gene name synonym)|uniprotkb:CG42551(orf name)	psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533752|imex:IM-19333-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001247347.1|refseq:NP_001247348.1|refseq:NP_001163757.1|refseq:NP_524998.1|refseq:NP_733244.5|refseq:NP_733245.1|flybase:FBgn0261618|ensemblmetazoa:FBgn0261618(gene)|ensemblmetazoa:FBtr0301180(transcript)|ensemblmetazoa:FBtr0306389(transcript)|ensemblmetazoa:FBtr0306390(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007053"(spindle assembly involved in male meiosis)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390	refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization)	-	-	-	figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:Lp0+tdf9WLnxphtiNJz1/2g1D6A7227	rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227	intact-crc:74D21C218BCA688A|rigid:mrry4qJ5dTDy+vRgHlXR0BT7FW0	false	glutathione s tranferase tag:?-?|sufficient binding region:?-?	his tag:?-?|32p radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P00522	uniprotkb:P16621	intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523	intact:EBI-668630|uniprotkb:Q960M3|uniprotkb:Q9VIS8|ensemblmetazoa:FBpp0080801	psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym)	psi-mi:lar_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:dLAR(gene name synonym)|uniprotkb:Lar(gene name)|psi-mi:Lar(display_short)|uniprotkb:CG10443(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533969|imex:IM-19333-5	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)	refseq:NP_523604.2|flybase:FBgn0000464|dip:DIP-38648N|ensemblmetazoa:FBgn0000464(gene)|ensemblmetazoa:FBtr0081260(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007412"(axon target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0045467"(R7 cell development)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0120034"(positive regulation of plasma membrane bounded cell projection assembly)|go:"GO:1903386"(negative regulation of homophilic cell adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2YD1|rcsb pdb:3PXJ|rcsb pdb:6X38|reactome:R-DME-388844|reactome:R-DME-8849932	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:2E|resulting-ptm:Phosphorylation of Larp|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227	rogid:rFF+oNmRMa0r6iVk4/gea7ozJfE7227	intact-crc:788FD6880ABE81D5|rigid:XZnoIcIV5XN+Rh0GF8lIg/xh3S4	false	his tag:?-?	sufficient binding region:1737-2029|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16620	uniprotkb:P00522	intact:EBI-676392|uniprotkb:Q8IGY3|uniprotkb:Q9VU03|ensemblmetazoa:FBpp0075645	intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523	psi-mi:ptp69_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:Ptp69D(gene name)|psi-mi:Ptp69D(display_short)|uniprotkb:DPTP(gene name synonym)|uniprotkb:CG10975(orf name)	psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533984|imex:IM-19333-6	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524048.2|refseq:NP_788502.1|flybase:FBgn0014007|ensemblmetazoa:FBgn0014007(gene)|ensemblmetazoa:FBtr0075913(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007415"(defasciculation of motor neuron axon)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0030424"(axon)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0097155"(fasciculation of sensory neuron axon)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:P16620	go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	figure legend:2F|resulting-ptm:Phosphorylation of PTP69d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:YOMEA3aIvtEsQt1qTG+BVCReyuE7227	rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227	intact-crc:C001FDDB1AAB964B|rigid:7PoXmMCrVQaAaFDVGZMB+HilXvU	false	glutathione s tranferase tag:?-?|sufficient binding region:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P16621	uniprotkb:Q8T4F7	intact:EBI-668630|uniprotkb:Q960M3|uniprotkb:Q9VIS8|ensemblmetazoa:FBpp0080801	intact:EBI-466810|uniprotkb:A4UZP3|uniprotkb:Q24035|uniprotkb:Q86NN6|uniprotkb:Q8MMB3|uniprotkb:Q9V8R3|uniprotkb:B7YZL0|ensemblmetazoa:FBpp0113115	psi-mi:lar_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:dLAR(gene name synonym)|uniprotkb:Lar(gene name)|psi-mi:Lar(display_short)|uniprotkb:CG10443(orf name)	psi-mi:ena_drome(display_long)|uniprotkb:CG15112(orf name)|uniprotkb:ena(gene name)|psi-mi:ena(display_short)|uniprotkb:enb(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1534008|imex:IM-19333-7	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523604.2|flybase:FBgn0000464|dip:DIP-38648N|ensemblmetazoa:FBgn0000464(gene)|ensemblmetazoa:FBtr0081260(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007412"(axon target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0045467"(R7 cell development)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0120034"(positive regulation of plasma membrane bounded cell projection assembly)|go:"GO:1903386"(negative regulation of homophilic cell adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2YD1|rcsb pdb:3PXJ|rcsb pdb:6X38|reactome:R-DME-388844|reactome:R-DME-8849932	refseq:NP_001014536.1|refseq:NP_001014537.1|refseq:NP_001137709.1|refseq:NP_725857.1|refseq:NP_725858.1|refseq:NP_725859.2|flybase:FBgn0000578|go:"GO:1990255"(subsynaptic reticulum organization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|reactome:R-DME-446353|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060288"(formation of a compartment boundary)|go:"GO:0071212"(subsynaptic reticulum)|ensemblmetazoa:FBgn0000578(gene)|ensemblmetazoa:FBtr0114623(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007390"(germ-band shortening)|go:"GO:0007391"(dorsal closure)|go:"GO:0007396"(suture of dorsal opening)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008258"(head involution)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032433"(filopodium tip)|go:"GO:0032956"(regulation of actin cytoskeleton organization)	go:"GO:0006470"(protein dephosphorylation)|go:"GO:0004725"(protein tyrosine phosphatase activity)	-	-	figure legend:6|resulting-ptm:Loss of phosphate group.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:rFF+oNmRMa0r6iVk4/gea7ozJfE7227	rogid:xKpOtgVG9/CT4HmGujHkDmw/G/o7227	intact-crc:7E3F3F5CC1B7F392|rigid:Od9hgNVSQy49RrvCnFM17roZu8M	false	glutathione s tranferase tag:?-?|sufficient binding region:1452-1766|mutation decreasing interaction:1670-1670	his tag:?-?|O4'-phospho-L-tyrosine:?-?|32p radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00522	uniprotkb:P16621	intact:EBI-534090|uniprotkb:Q95TV1|uniprotkb:Q9VV86|ensemblmetazoa:FBpp0075116|ensemblmetazoa:FBpp0311523	intact:EBI-668630|uniprotkb:Q960M3|uniprotkb:Q9VIS8|ensemblmetazoa:FBpp0080801	psi-mi:abl_drome(display_long)|uniprotkb:Protein abelson(gene name synonym)|uniprotkb:Abl(gene name)|psi-mi:Abl(display_short)|uniprotkb:ABL-1(gene name synonym)|uniprotkb:Dash(gene name synonym)|uniprotkb:CG4032(orf name)|uniprotkb:D-ash(gene name synonym)	psi-mi:lar_drome(display_long)|uniprotkb:Protein-tyrosine-phosphate phosphohydrolase(gene name synonym)|uniprotkb:dLAR(gene name synonym)|uniprotkb:Lar(gene name)|psi-mi:Lar(display_short)|uniprotkb:CG10443(orf name)	psi-mi:"MI:0434"(phosphatase assay)	Wills et al. (1999)	pubmed:10069336|imex:IM-19333	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1534017|imex:IM-19333-8	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048749"(compound eye development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0072499"(photoreceptor cell axon guidance)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016199"(axon midline choice point recognition)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|reactome:R-DME-2029482|reactome:R-DME-428890|reactome:R-DME-525793|reactome:R-DME-5663213|reactome:R-DME-69231|reactome:R-DME-8939236|reactome:R-DME-9013149|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0045202"(synapse)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001287085.1|refseq:NP_524843.2|flybase:FBgn0000017|ensemblmetazoa:FBgn0000017(gene)|ensemblmetazoa:FBtr0075357(transcript)|ensemblmetazoa:FBtr0345369(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007303"(cytoplasmic transport, nurse cell to oocyte)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007419"(ventral cord development)|go:"GO:0007611"(learning or memory)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)	refseq:NP_523604.2|flybase:FBgn0000464|dip:DIP-38648N|ensemblmetazoa:FBgn0000464(gene)|ensemblmetazoa:FBtr0081260(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007412"(axon target recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0045467"(R7 cell development)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060269"(centripetally migrating follicle cell migration)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0120034"(positive regulation of plasma membrane bounded cell projection assembly)|go:"GO:1903386"(negative regulation of homophilic cell adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2YD1|rcsb pdb:3PXJ|rcsb pdb:6X38|reactome:R-DME-388844|reactome:R-DME-8849932	go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)	-	-	figure legend:6|resulting-ptm:Loss of phosphorylation.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/18	2014/10/16	rogid:WKRZSDhhHjjnTfp73ErazsbPW9o7227	rogid:rFF+oNmRMa0r6iVk4/gea7ozJfE7227	intact-crc:5616A84BF8CB35B2|rigid:XZnoIcIV5XN+Rh0GF8lIg/xh3S4	false	his tag:?-?|32p radiolabel:?-?|O4'-phospho-L-tyrosine:?-?	mutation decreasing interaction:1670-1670|glutathione s tranferase tag:?-?|sufficient binding region:1452-1766	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)