#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q63ZW7 uniprotkb:P49655 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-706185|uniprotkb:Q62790 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:kcj10_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)|uniprotkb:ATP-sensitive inward rectifier potassium channel KAB-2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.1"(gene name synonym)|uniprotkb:BIR10(gene name synonym)|uniprotkb:"Brain-specific inwardly rectifying K(+) channel 1"(gene name synonym)|uniprotkb:Kcnj10(gene name)|psi-mi:Kcnj10(display_short)|uniprotkb:Kab-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689438|mint:MINT-1890737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1890747(identity) refseq:NP_113790.2|refseq:XP_008767959.1|rgd:61822|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|refseq:XP_017454263.1|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296067|reactome:R-RNO-997272|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0009637"(response to blue light)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0051938"(L-glutamate import)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|mint:MINT-1890738(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:ri6d3VbUvSLj12uMiqruQGL09sE10116 intact-crc:40ED3E87C6F6A687|rigid:/TBFWha+cJ5bGQ7U0YXhBYPU6K4 false tag:?-?(MINT-1890753) binding-associated region:373-379(MINT-1890739)|mutation disrupting interaction:379-379(MINT-1890762)|mutation disrupting interaction:1-374(MINT-1891130)|mutation disrupting interaction:377-377(MINT-1890760)|tag:?-?(MINT-1890745) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:P35436 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689421|mint:MINT-1890640 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1890641(identity) refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|mint:MINT-1890642(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090 intact-crc:95FD0AC7B02F5DCC|rigid:2MVlsl2gLvrLA+Ox9tcorV3RuGU false tag:?-?(MINT-1890644) tag:?-?(MINT-1890652) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q62645 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-631067|uniprotkb:Q63381|uniprotkb:Q63382|uniprotkb:Q63729|uniprotkb:Q63730|ensembl:ENSRNOP00000028615 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde4_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2D(gene name synonym)|uniprotkb:Grin2d(gene name)|psi-mi:Grin2d(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-4(gene name synonym)|uniprotkb:GluN2D(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689537|mint:MINT-1890855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1890866(identity) rgd:2740|refseq:NP_073634.1|ensembl:ENSRNOG00000021063(gene)|ensembl:ENSRNOT00000028615(transcript)|go:"GO:0001964"(startle response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016595"(glutamate binding)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3OEK|rcsb pdb:3OEL|rcsb pdb:3OEM|rcsb pdb:3OEN|rcsb pdb:4JWY|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|refseq:XP_008757539.1|mint:MINT-1890856(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:EI0xEBqUTBpq1D93yQqU4XLHdc810116 intact-crc:B8665682C8ADDDCB|rigid:3LI2BuPTncbNuGsbJ4GM57HAUPo false tag:?-?(MINT-1890872) tag:?-?(MINT-1890864)|binding-associated region:1317-1323(MINT-1890857) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q00960 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-396905|uniprotkb:Q62684 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde2_rat(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689473|mint:MINT-1890807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1890822(identity) rgd:2738|refseq:NP_036706.1|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010350"(cellular response to magnesium starvation)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904644"(cellular response to curcumin)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3JPW|rcsb pdb:3JPY|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4PE5|rcsb pdb:5B3J|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5TPZ|rcsb pdb:6CNA|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|mint:Q00960|dip:DIP-33702N|mint:MINT-1890808(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:dbOLObdhW/ts7GuZ0k8UIII99m010116 intact-crc:88EFF75099F27955|rigid:zBSINQCHdDEWR0Gf+QZIx3gq58w false tag:?-?(MINT-1890828) binding-associated region:1476-1482(MINT-1890813)|tag:?-?(MINT-1890820) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q62644 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-8689494|intact:MINT-1891244 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:q62644_rat(display_long) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689517|mint:MINT-1890834 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1890845(identity) interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR018884|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|mint:MINT-1890835(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:T2|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:KdrBM7uSmWXKHftNoUIsrHU6YAw10116 intact-crc:6006970ED82135A1|rigid:WeCPUyERB7GYhRUGNg+hN92nMuU false tag:?-?(MINT-1890846) tag:?-?(MINT-1890843)|binding-associated region:1244-1250(MINT-1890836) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62645 uniprotkb:Q62108 intact:EBI-631067|uniprotkb:Q63381|uniprotkb:Q63382|uniprotkb:Q63729|uniprotkb:Q63730|ensembl:ENSRNOP00000028615 intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1 psi-mi:nmde4_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2D(gene name synonym)|uniprotkb:Grin2d(gene name)|psi-mi:Grin2d(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-4(gene name synonym)|uniprotkb:GluN2D(gene name synonym) psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689558|mint:MINT-1890876 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2740|refseq:NP_073634.1|ensembl:ENSRNOG00000021063(gene)|ensembl:ENSRNOT00000028615(transcript)|go:"GO:0001964"(startle response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016595"(glutamate binding)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3OEK|rcsb pdb:3OEL|rcsb pdb:3OEM|rcsb pdb:3OEN|rcsb pdb:4JWY|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|refseq:XP_008757539.1|mint:MINT-1890877(identity) ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N|mint:MINT-1890887(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:EI0xEBqUTBpq1D93yQqU4XLHdc810116 rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090 intact-crc:FC19FFA66077B474|rigid:Mj+OkNMcdwkVxuyP5FzxQxFspLA false binding-associated region:1317-1323(MINT-1890878)|tag:?-?(MINT-1890885) binding-associated region:1-428(MINT-1890896)|tag:?-?(MINT-1890888) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62644 uniprotkb:Q62108 intact:EBI-8689494|intact:MINT-1891244 intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1 psi-mi:q62644_rat(display_long) psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689583|mint:MINT-1890899 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR018884|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|mint:MINT-1890910(identity) ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N|mint:MINT-1890900(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:KdrBM7uSmWXKHftNoUIsrHU6YAw10116 rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090 intact-crc:1A65F33657417D9F|rigid:q84G8YpMX/A/Q8GBvaaWnrgxgFE false tag:?-?(MINT-1890911)|binding-associated region:1244-1250(MINT-1890918) binding-associated region:1-428(MINT-1890901)|tag:?-?(MINT-1890908) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P19491 uniprotkb:P97879 intact:EBI-77718|uniprotkb:Q9R174 intact:EBI-936113 psi-mi:gria2_rat(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym) psi-mi:grip1_rat(display_long)|uniprotkb:Grip1(gene name)|psi-mi:Grip1(display_short)|uniprotkb:AMPA receptor-interacting protein GRIP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689657|mint:MINT-1890967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|interpro:IPR028082|rcsb pdb:1FTJ|rcsb pdb:1FTK|rcsb pdb:1FTL|rcsb pdb:1FTM|rcsb pdb:1FTO|rcsb pdb:1FW0|rcsb pdb:1GR2|rcsb pdb:1LB8|rcsb pdb:1LB9|rcsb pdb:1LBB|rcsb pdb:1LBC|rcsb pdb:1M5B|rcsb pdb:1M5C|rcsb pdb:1M5D|rcsb pdb:1M5E|rcsb pdb:1M5F|rcsb pdb:1MM6|rcsb pdb:1MM7|rcsb pdb:1MQD|rcsb pdb:1MQG|rcsb pdb:1MQH|rcsb pdb:1MQI|rcsb pdb:1MQJ|rcsb pdb:1MS7|rcsb pdb:1MXU|rcsb pdb:1MXV|rcsb pdb:1MXW|rcsb pdb:1MXX|rcsb pdb:1MXY|rcsb pdb:1MXZ|rcsb pdb:1MY0|rcsb pdb:1MY1|rcsb pdb:1MY2|rcsb pdb:1MY3|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060992"(response to fungicide)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019865"(immunoglobulin binding)|rcsb pdb:1MY4|rcsb pdb:1N0T|rcsb pdb:1NNK|rcsb pdb:1NNP|rcsb pdb:1P1N|rcsb pdb:1P1O|rcsb pdb:1P1Q|rcsb pdb:1P1U|rcsb pdb:1P1W|rcsb pdb:1SYH|rcsb pdb:1SYI|rcsb pdb:1WVJ|rcsb pdb:1XHY|rcsb pdb:2AIX|rcsb pdb:2AL4|rcsb pdb:2AL5|rcsb pdb:2ANJ|rcsb pdb:2CMO|rcsb pdb:2GFE|rcsb pdb:2I3V|rcsb pdb:2I3W|rcsb pdb:2P2A|rcsb pdb:2UXA|rcsb pdb:2XX7|rcsb pdb:2XX8|rcsb pdb:2XX9|rcsb pdb:2XXH|rcsb pdb:2XXI|rcsb pdb:3B6Q|rcsb pdb:5NIH|rcsb pdb:5NS9|rcsb pdb:5O9A|rcsb pdb:5OEW|rcsb pdb:5VHW|rcsb pdb:5VHX|rcsb pdb:5VHY|rcsb pdb:5VHZ|rcsb pdb:5VOT|rcsb pdb:5VOU|rcsb pdb:5VOV|rcsb pdb:5WEK|rcsb pdb:5WEL|rcsb pdb:5WEM|rcsb pdb:5WEN|rcsb pdb:5WEO|rcsb pdb:6DLZ|rcsb pdb:6DM0|rcsb pdb:6DM1|rcsb pdb:6FAZ|rcsb pdb:6FQG|rcsb pdb:6FQH|rcsb pdb:6FQI|rcsb pdb:6FQJ|rcsb pdb:6FQK|rcsb pdb:6GIV|rcsb pdb:6GL4|rcsb pdb:6HC9|rcsb pdb:6HCA|rcsb pdb:6HCB|rcsb pdb:6HCC|rcsb pdb:6HCH|rcsb pdb:6NJL|rcsb pdb:6NJM|rcsb pdb:6NJN|rcsb pdb:6O9G|rcsb pdb:6PEQ|rcsb pdb:6Q54|rcsb pdb:6Q60|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:3B6T|rcsb pdb:3B6W|rcsb pdb:3B7D|rcsb pdb:3BBR|rcsb pdb:3BFT|rcsb pdb:3BFU|rcsb pdb:3BKI|rcsb pdb:3DP6|rcsb pdb:3H03|rcsb pdb:3H06|rcsb pdb:3H5V|rcsb pdb:3H5W|rcsb pdb:3H6T|rcsb pdb:3H6U|rcsb pdb:3H6V|rcsb pdb:3H6W|rcsb pdb:3HSY|rcsb pdb:3IJO|rcsb pdb:3IJX|rcsb pdb:3IK6|rcsb pdb:3IL1|rcsb pdb:3ILT|rcsb pdb:3ILU|rcsb pdb:3KG2|rcsb pdb:3KGC|rcsb pdb:3LSF|rcsb pdb:3LSL|rcsb pdb:3M3L|rcsb pdb:3N6V|rcsb pdb:3O28|rcsb pdb:3O29|rcsb pdb:3O2A|rcsb pdb:3O2J|rcsb pdb:3O6G|rcsb pdb:3O6H|rcsb pdb:3O6I|rcsb pdb:3PD8|rcsb pdb:3PD9|rcsb pdb:3PMV|rcsb pdb:3PMW|rcsb pdb:3PMX|rcsb pdb:6RUQ|rcsb pdb:6U5S|rcsb pdb:6U6I|rcsb pdb:6UCB|rcsb pdb:6UD4|rcsb pdb:6UD8|rcsb pdb:6XSR|rcsb pdb:6YK2|rcsb pdb:6YK3|rcsb pdb:6YK4|rcsb pdb:6YK5|rcsb pdb:6YK6|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-399710|reactome:R-RNO-416993|reactome:R-RNO-438066|rcsb pdb:3RTF|rcsb pdb:3RTW|rcsb pdb:3T93|rcsb pdb:3T96|rcsb pdb:3T9H|rcsb pdb:3T9U|rcsb pdb:3T9V|rcsb pdb:3T9X|rcsb pdb:3TDJ|rcsb pdb:3TKD|rcsb pdb:3TZA|rcsb pdb:4FAT|rcsb pdb:4G8M|rcsb pdb:4GXS|rcsb pdb:4H8J|rcsb pdb:4IGT|rcsb pdb:4ISU|rcsb pdb:4IY5|rcsb pdb:4IY6|rcsb pdb:4L17|rcsb pdb:4LZ5|rcsb pdb:4LZ7|rcsb pdb:4LZ8|rcsb pdb:4N07|rcsb pdb:4O3A|rcsb pdb:4O3B|rcsb pdb:4O3C|rcsb pdb:4Q30|rcsb pdb:4U1O|rcsb pdb:4U1W|rcsb pdb:4U1X|rcsb pdb:4U1Y|rcsb pdb:4U1Z|rcsb pdb:4U21|rcsb pdb:4U22|rcsb pdb:4U23|rcsb pdb:4U2P|rcsb pdb:4U2Q|rcsb pdb:4U2R|rcsb pdb:4U4F|rcsb pdb:4U4G|rcsb pdb:4U4S|rcsb pdb:4U4X|rcsb pdb:4U5B|rcsb pdb:4U5C|rcsb pdb:4U5D|rcsb pdb:4U5E|rcsb pdb:4U5F|rcsb pdb:4UQ6|rcsb pdb:4UQJ|rcsb pdb:4UQK|rcsb pdb:4X48|rcsb pdb:4YMA|rcsb pdb:4YU0|rcsb pdb:4Z0I|rcsb pdb:5BUU|rcsb pdb:5CBR|rcsb pdb:5CBS|rcsb pdb:5ELV|rcsb pdb:5FHM|rcsb pdb:5FHN|rcsb pdb:5FHO|rcsb pdb:5FTH|rcsb pdb:5FTI|rcsb pdb:5FWX|rcsb pdb:5FWY|rcsb pdb:5IDE|rcsb pdb:5IDF|rcsb pdb:5JEI|rcsb pdb:5KBS|rcsb pdb:5KBT|rcsb pdb:5KBU|rcsb pdb:5KBV|rcsb pdb:5KK2|rcsb pdb:5L1B|rcsb pdb:5L1E|rcsb pdb:5L1F|rcsb pdb:5L1G|rcsb pdb:5L1H|rcsb pdb:5N6P|rcsb pdb:5NG9|refseq:NP_001077280.1|refseq:NP_058957.1|rgd:61862|mint:P19491|dip:DIP-30952N|mint:MINT-1890968(identity) rgd:621667|refseq:NP_114458.1|dip:DIP-37486N|reactome:R-RNO-416993|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030026|interpro:IPR036034|interpro:IPR041489|interpro:IPR043545|rcsb pdb:1M5Z|rcsb pdb:1N7E|rcsb pdb:1N7F|rcsb pdb:1P1D|rcsb pdb:1P1E|rcsb pdb:2QT5|mint:MINT-1890978(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:zeQRRvspsIuRyA9kKA7kyIr8HqE10116 rogid:/maXdOoLsS4jIhMXA3kFkixeJ7M10116 intact-crc:749C8ABBBAD26670|rigid:8KqDMaZBEr/t6R/7Dd80s/fpMCI false binding-associated region:877-883(MINT-1890969)|tag:?-?(MINT-1890976) binding-associated region:333-808(MINT-1890986)|tag:?-?(MINT-1890979) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62108 uniprotkb:Q00960 intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1 intact:EBI-396905|uniprotkb:Q62684 psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym) psi-mi:nmde2_rat(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689632|mint:MINT-1890944 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N|mint:MINT-1890945(identity) rgd:2738|refseq:NP_036706.1|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010350"(cellular response to magnesium starvation)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904644"(cellular response to curcumin)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3JPW|rcsb pdb:3JPY|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4PE5|rcsb pdb:5B3J|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5TPZ|rcsb pdb:6CNA|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|mint:Q00960|dip:DIP-33702N|mint:MINT-1890955(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090 rogid:dbOLObdhW/ts7GuZ0k8UIII99m010116 intact-crc:1DA4A14A4CC0BB4C|rigid:mDhYMtJvYj/AGPhguEJXzargUb0 false binding-associated region:1-428(MINT-1890946)|tag:?-?(MINT-1890953) tag:?-?(MINT-1890956)|binding-associated region:1477-1482(MINT-1890963) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62108 uniprotkb:P35436 intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1 intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900 psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym) psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689607|mint:MINT-1890922 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N|mint:MINT-1890933(identity) refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|mint:MINT-1890923(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090 rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090 intact-crc:AE6CB681EB4F7011|rigid:Z0n5zQLcAR7l0DRmnDhuwxh6T5g false tag:?-?(MINT-1890934)|binding-associated region:1-428(MINT-1890941) binding-associated region:1458-1464(MINT-1890924)|tag:?-?(MINT-1890931) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23385 uniprotkb:Q9Z214 intact:EBI-4410410 intact:EBI-2338940|uniprotkb:O08567|uniprotkb:O88800|uniprotkb:Q9QUJ8|uniprotkb:Q9QWN5 psi-mi:grm1_rat(display_long)|uniprotkb:Grm1(gene name)|psi-mi:Grm1(display_short)|uniprotkb:Gprc1a(gene name synonym)|uniprotkb:Mglur1(gene name synonym) psi-mi:home1_rat(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689707|mint:MINT-1891014 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:2742|refseq:NP_001107802.1|refseq:NP_058707.1|mint:P23385|dip:DIP-44897N|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001256(GPCR, family 3, metabotropic glutamate receptor 1)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:1EWK|rcsb pdb:1EWT|rcsb pdb:1EWV|rcsb pdb:1ISR|rcsb pdb:1ISS|reactome:R-RNO-416476|reactome:R-RNO-420499|reactome:R-RNO-6794361|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0014048"(regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0038037"(G protein-coupled receptor dimeric complex)|go:"GO:0038038"(G protein-coupled receptor homodimeric complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098872"(G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|mint:MINT-1891015(identity) rgd:628725|refseq:NP_113895.1|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:XP_006231837.1|mint:Q9Z214|interpro:IPR044100|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|rcsb pdb:1DDV|rcsb pdb:1DDW|rcsb pdb:1I2H|rcsb pdb:3CVE|reactome:R-RNO-6794361|mint:MINT-1891025(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:Cy8lKGGALjqGP/e25gw+KqejF5c10116 rogid:7yzSvJnto6+5zXH000SPZOIYe3w10116 intact-crc:23FC9CB6B7EC2C73|rigid:Hoy0BlqobTm6RgyFzA+7FEMHfZ4 false binding-associated region:1193-1199(MINT-1891016)|tag:?-?(MINT-1891023) tag:?-?(MINT-1891026) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z214 uniprotkb:P31424 intact:EBI-2338940|uniprotkb:O08567|uniprotkb:O88800|uniprotkb:Q9QUJ8|uniprotkb:Q9QWN5 intact:EBI-2902734 psi-mi:home1_rat(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym) psi-mi:grm5_rat(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)|uniprotkb:Gprc1e(gene name synonym)|uniprotkb:Mglur5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689727|mint:MINT-1891078 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628725|refseq:NP_113895.1|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:XP_006231837.1|mint:Q9Z214|interpro:IPR044100|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|rcsb pdb:1DDV|rcsb pdb:1DDW|rcsb pdb:1I2H|rcsb pdb:3CVE|reactome:R-RNO-6794361|mint:MINT-1891079(identity) go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|rcsb pdb:1DDV|reactome:R-RNO-416476|reactome:R-RNO-420499|reactome:R-RNO-6794361|rgd:2746|refseq:NP_058708.1|refseq:XP_017444267.1|refseq:XP_017444268.1|refseq:XP_017444269.1|refseq:XP_017444270.1|refseq:XP_006229721.1|dip:DIP-41263N|mint:P31424|mint:MINT-1891087(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:7yzSvJnto6+5zXH000SPZOIYe3w10116 rogid:ZXlFrgUfGF+zPgfi7QuTXqMSZvk10116 intact-crc:8C5E5D5EBEC212C7|rigid:H97bLZJdEjtmy4A7EF2CRewTkI8 false tag:?-?(MINT-1891085) tag:?-?(MINT-1891095)|binding-associated region:1197-1203(MINT-1891088) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P97879 uniprotkb:P19492 intact:EBI-936113 intact:EBI-77764 psi-mi:grip1_rat(display_long)|uniprotkb:Grip1(gene name)|psi-mi:Grip1(display_short)|uniprotkb:AMPA receptor-interacting protein GRIP1(gene name synonym) psi-mi:gria3_rat(display_long)|uniprotkb:Gria3(gene name)|psi-mi:Gria3(display_short)|uniprotkb:Glur3(gene name synonym)|uniprotkb:GluR-K3(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 3(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 3(gene name synonym)|uniprotkb:GluR-C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689682|mint:MINT-1890991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621667|refseq:NP_114458.1|dip:DIP-37486N|reactome:R-RNO-416993|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030026|interpro:IPR036034|interpro:IPR041489|interpro:IPR043545|rcsb pdb:1M5Z|rcsb pdb:1N7E|rcsb pdb:1N7F|rcsb pdb:1P1D|rcsb pdb:1P1E|rcsb pdb:2QT5|mint:MINT-1890992(identity) interpro:IPR019594|interpro:IPR028082|rcsb pdb:3DLN|rcsb pdb:3DP4|rcsb pdb:3LSW|rcsb pdb:3LSX|rcsb pdb:3M3F|rcsb pdb:3M3K|rcsb pdb:3O21|rcsb pdb:3P3W|rcsb pdb:3RT6|rcsb pdb:3RT8|rcsb pdb:4F1Y|rcsb pdb:4F22|rcsb pdb:4F29|rcsb pdb:4F2O|rcsb pdb:4F2Q|rcsb pdb:4F31|rcsb pdb:4F39|rcsb pdb:4F3B|rcsb pdb:4F3G|rcsb pdb:5FWY|interpro:IPR001828(Extracellular ligand-binding receptor)|rcsb pdb:5IDE|rcsb pdb:5IDF|rcsb pdb:6FLR|rcsb pdb:6NJM|rcsb pdb:6NJN|rcsb pdb:6FPJ|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060992"(response to fungicide)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|rgd:70958|refseq:NP_001106213.1|refseq:NP_116785.2|dip:DIP-30954N|reactome:R-RNO-438066|reactome:R-RNO-399710|reactome:R-RNO-399719|reactome:R-RNO-416993|reactome:R-RNO-8849932|mint:MINT-1891002(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:/maXdOoLsS4jIhMXA3kFkixeJ7M10116 rogid:mrrYoOdOahJ+VbAGzuoBPYvGV1410116 intact-crc:489F308BB184F7F4|rigid:W8cnhBR+Q3JgnyrSSkIey5/Yqv0 false tag:?-?(MINT-1891000)|binding-associated region:333-808(MINT-1890993) tag:?-?(MINT-1891010)|binding-associated region:882-888(MINT-1891003) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P35439-4 uniprotkb:Q62108 intact:EBI-877935|intact:EBI-8689752|intact:MINT-101390 intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1 psi-mi:p35439-4(display_long)|uniprotkb:Grin1(gene name)|psi-mi:Grin1(display_short)|uniprotkb:Nmdar1(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit zeta-1(gene name synonym) psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689747|mint:MINT-1891814 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-877897(nmdz1_rat)|mint:MINT-1891825(identity) ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N|mint:MINT-1891815(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:+MGsYdg7wRELq2fKRBplRMXzgUQ10116 rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090 intact-crc:27555961EE78C42D|rigid:E8AeiCyC0x/z8WsEkUKw2klgAuE false binding-associated region:886-922(MINT-1891826)|tag:?-?(MINT-1891833) binding-associated region:1-428(MINT-1891816)|tag:?-?(MINT-1891823) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:P35436 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689782|mint:MINT-1891889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891900(identity) refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|mint:MINT-1891890(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090 intact-crc:A8F508442DD4128E|rigid:2MVlsl2gLvrLA+Ox9tcorV3RuGU false tag:?-?(MINT-1891906) tag:?-?(MINT-1891898)|binding-associated region:1458-1464(MINT-1891891) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q99712 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-7082607|ensembl:ENSP00000331698|ensembl:ENSP00000381904|ensembl:ENSP00000381905|ensembl:ENSP00000381907|ensembl:ENSP00000381911|ensembl:ENSP00000479100|ensembl:ENSP00000484960|intact:MINT-103775|uniprotkb:Q96L28|uniprotkb:D3DSH5|uniprotkb:Q99446|uniprotkb:O00564 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:kcj15_human(display_long)|uniprotkb:KCNJ15(gene name)|psi-mi:KCNJ15(display_short)|uniprotkb:KCNJ14(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 15(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.2"(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir1.3"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689848|mint:MINT-1891163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891164(identity) refseq:XP_011527862.1|refseq:XP_011527863.1|ensembl:ENSG00000157551(gene)|ensembl:ENST00000328656(transcript)|ensembl:ENST00000398930(transcript)|ensembl:ENST00000398932(transcript)|ensembl:ENST00000398934(transcript)|ensembl:ENST00000398938(transcript)|ensembl:ENST00000612702(transcript)|ensembl:ENST00000613499(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003270(Potassium channel, inwardly rectifying, Kir1.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-HSA-1296041|reactome:R-HSA-997272|refseq:XP_016883832.1|refseq:XP_016883833.1|refseq:XP_016883834.1|refseq:NP_001263365.1|refseq:NP_733933.1|refseq:NP_001263368.1|refseq:NP_001263366.1|refseq:NP_002234.2|refseq:NP_001263364.1|refseq:NP_001263367.1|refseq:NP_733932.1|refseq:XP_005261032.1|refseq:XP_006724065.1|mint:MINT-1891171(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:mint|function:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium|comment:"Stoichiometry: 1.0" figure legend:T1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:TiE/A9/tLsonRMg7/KsThkWgr8Q9606 intact-crc:47628985FE8B48A6|rigid:Piw0/znqvv9HQDcHcfq6V9gOMeM false tag:?-?(MINT-1891169) tag:?-?(MINT-1891180) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q00960 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-396905|uniprotkb:Q62684 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde2_rat(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689960|mint:MINT-1891186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891197(identity) rgd:2738|refseq:NP_036706.1|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010350"(cellular response to magnesium starvation)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904644"(cellular response to curcumin)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3JPW|rcsb pdb:3JPY|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4PE5|rcsb pdb:5B3J|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5TPZ|rcsb pdb:6CNA|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|mint:Q00960|dip:DIP-33702N|mint:MINT-1891187(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:dbOLObdhW/ts7GuZ0k8UIII99m010116 intact-crc:1763ED52C88F7941|rigid:zBSINQCHdDEWR0Gf+QZIx3gq58w false binding-associated region:197-358(MINT-1891279)|tag:?-?(MINT-1891198) tag:?-?(MINT-1891195) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q00960 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-396905|uniprotkb:Q62684 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde2_rat(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689982|mint:MINT-1891284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891293(identity) rgd:2738|refseq:NP_036706.1|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010350"(cellular response to magnesium starvation)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904644"(cellular response to curcumin)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3JPW|rcsb pdb:3JPY|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4PE5|rcsb pdb:5B3J|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5TPZ|rcsb pdb:6CNA|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|mint:Q00960|dip:DIP-33702N|mint:MINT-1891285(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:dbOLObdhW/ts7GuZ0k8UIII99m010116 intact-crc:5255A84A7FC4DF65|rigid:zBSINQCHdDEWR0Gf+QZIx3gq58w false tag:?-?(MINT-1891302)|binding-associated region:311-491(MINT-1891294) tag:?-?(MINT-1891291) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:P49655 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-706185|uniprotkb:Q62790 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:kcj10_rat(display_long)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)|uniprotkb:ATP-sensitive inward rectifier potassium channel KAB-2(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.1"(gene name synonym)|uniprotkb:BIR10(gene name synonym)|uniprotkb:"Brain-specific inwardly rectifying K(+) channel 1"(gene name synonym)|uniprotkb:Kcnj10(gene name)|psi-mi:Kcnj10(display_short)|uniprotkb:Kab-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690004|mint:MINT-1891306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891307(identity) refseq:NP_113790.2|refseq:XP_008767959.1|rgd:61822|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|refseq:XP_017454263.1|interpro:IPR040445|interpro:IPR041647|reactome:R-RNO-1296041|reactome:R-RNO-1296067|reactome:R-RNO-997272|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0009637"(response to blue light)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0051938"(L-glutamate import)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|mint:MINT-1891318(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:ri6d3VbUvSLj12uMiqruQGL09sE10116 intact-crc:BCBAD0578FC9A419|rigid:/TBFWha+cJ5bGQ7U0YXhBYPU6K4 false tag:?-?(MINT-1891316)|binding-associated region:197-358(MINT-1891308) tag:?-?(MINT-1891319) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q00961 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-631045 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde3_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2C(gene name synonym)|uniprotkb:Grin2c(gene name)|psi-mi:Grin2c(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690026|mint:MINT-1891543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891544(identity) rgd:2739|refseq:NP_036707.3|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR018884|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009611"(response to wounding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0033058"(directional locomotion)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|refseq:XP_006247769.1|refseq:XP_006247771.1|interpro:IPR028082|refseq:XP_017452475.1|refseq:XP_017452476.1|refseq:XP_017452477.1|refseq:XP_017452478.1|refseq:XP_017452479.1|refseq:XP_017452480.1|refseq:XP_017452481.1|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-1891555(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:DNWgJGwL2992SEfrd3xZwHfJmdY10116 intact-crc:EA9F8E6018E37EF8|rigid:PUgD6givzeSnD+TQ9UAjBpiswlI false binding-associated region:311-491(MINT-1891545)|tag:?-?(MINT-1891553) tag:?-?(MINT-1891561) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q62645 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-631067|uniprotkb:Q63381|uniprotkb:Q63382|uniprotkb:Q63729|uniprotkb:Q63730|ensembl:ENSRNOP00000028615 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde4_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2D(gene name synonym)|uniprotkb:Grin2d(gene name)|psi-mi:Grin2d(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-4(gene name synonym)|uniprotkb:GluN2D(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690048|mint:MINT-1891588 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891597(identity) rgd:2740|refseq:NP_073634.1|ensembl:ENSRNOG00000021063(gene)|ensembl:ENSRNOT00000028615(transcript)|go:"GO:0001964"(startle response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016595"(glutamate binding)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3OEK|rcsb pdb:3OEL|rcsb pdb:3OEM|rcsb pdb:3OEN|rcsb pdb:4JWY|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|refseq:XP_008757539.1|mint:MINT-1891589(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:EI0xEBqUTBpq1D93yQqU4XLHdc810116 intact-crc:00DE35144FB11DEE|rigid:3LI2BuPTncbNuGsbJ4GM57HAUPo false tag:?-?(MINT-1891598)|binding-associated region:311-491(MINT-1891605) tag:?-?(MINT-1891595) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q62888 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-7281302|intact:MINT-1891708 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nlgn2_rat(display_long)|uniprotkb:Nlgn2(gene name)|psi-mi:Nlgn2(display_short) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690119|mint:MINT-1891685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891696(identity) interpro:IPR030023|rgd:621118|refseq:NP_446444.1|interpro:IPR019819|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|go:"GO:0001966"(thigmotaxis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007630"(jump response)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0035176"(social behavior)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0072553"(terminal button organization)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098698"(postsynaptic specialization assembly)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1902474"(positive regulation of protein localization to synapse)|go:"GO:1904034"(positive regulation of t-SNARE clustering)|go:"GO:1904862"(inhibitory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|interpro:IPR029058|rcsb pdb:5V5V|reactome:R-RNO-6794361|mint:MINT-1891686(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:mint|function:Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures|comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:HlzMKXRXR/YD08sdzWZiyGs2g6A10116 intact-crc:D155ECE84731EFCE|rigid:fbpwxr6PK28tdJaI2k8f8PBjm4k false binding-associated region:197-358(MINT-1891704)|tag:?-?(MINT-1891697) binding-associated region:781-836(MINT-1891687)|tag:?-?(MINT-1891694) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q63376 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-8690070|intact:MINT-1891630|ensembl:ENSRNOP00000028651 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nrx2b_rat(display_long)|uniprotkb:Nrxn2(gene name)|psi-mi:Nrxn2(display_short)|uniprotkb:Neurexin II-beta(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690093|mint:MINT-1891609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891610(identity) refseq:XP_008758286.1|rgd:620211|ensembl:ENSRNOG00000021103(gene)|ensembl:ENSRNOT00000028651(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030534"(adult behavior)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035176"(social behavior)|go:"GO:0042297"(vocal learning)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0098793"(presynapse)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097109"(neuroligin family protein binding)|mint:MINT-1891621(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion|comment:mint|comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:Zmqp49mKl8HpdgvOCrpfkO9qZU410116 intact-crc:8A7FD9021D1A4C43|rigid:9pV9BguV+Oq/yQNzjW+NQOlldNE false tag:?-?(MINT-1891619)|binding-associated region:311-491(MINT-1891611) binding-associated region:524-662(MINT-1891682)|tag:?-?(MINT-1891622) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:P35436 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690167|mint:MINT-1891756 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891765(identity) refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|mint:MINT-1891757(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090 intact-crc:6CAF3092ED98A8D7|rigid:2MVlsl2gLvrLA+Ox9tcorV3RuGU false binding-associated region:311-491(MINT-1891773)|tag:?-?(MINT-1891766) tag:?-?(MINT-1891763) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99712 uniprotkb:Q63ZW7 intact:EBI-7082607|ensembl:ENSP00000331698|ensembl:ENSP00000381904|ensembl:ENSP00000381905|ensembl:ENSP00000381907|ensembl:ENSP00000381911|ensembl:ENSP00000479100|ensembl:ENSP00000484960|intact:MINT-103775|uniprotkb:Q96L28|uniprotkb:D3DSH5|uniprotkb:Q99446|uniprotkb:O00564 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 psi-mi:kcj15_human(display_long)|uniprotkb:KCNJ15(gene name)|psi-mi:KCNJ15(display_short)|uniprotkb:KCNJ14(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 15(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.2"(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir1.3"(gene name synonym) psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690145|mint:MINT-1891729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011527862.1|refseq:XP_011527863.1|ensembl:ENSG00000157551(gene)|ensembl:ENST00000328656(transcript)|ensembl:ENST00000398930(transcript)|ensembl:ENST00000398932(transcript)|ensembl:ENST00000398934(transcript)|ensembl:ENST00000398938(transcript)|ensembl:ENST00000612702(transcript)|ensembl:ENST00000613499(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003270(Potassium channel, inwardly rectifying, Kir1.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-HSA-1296041|reactome:R-HSA-997272|refseq:XP_016883832.1|refseq:XP_016883833.1|refseq:XP_016883834.1|refseq:NP_001263365.1|refseq:NP_733933.1|refseq:NP_001263368.1|refseq:NP_001263366.1|refseq:NP_002234.2|refseq:NP_001263364.1|refseq:NP_001263367.1|refseq:NP_733932.1|refseq:XP_005261032.1|refseq:XP_006724065.1|mint:MINT-1891741(identity) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891730(identity) - comment:mint|function:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium|comment:"Stoichiometry: 1.0" comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:TiE/A9/tLsonRMg7/KsThkWgr8Q9606 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 intact-crc:6C273F18EE961861|rigid:Piw0/znqvv9HQDcHcfq6V9gOMeM false tag:?-?(MINT-1891749) tag:?-?(MINT-1891739)|binding-associated region:197-358(MINT-1891731) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q99712 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-7082607|ensembl:ENSP00000331698|ensembl:ENSP00000381904|ensembl:ENSP00000381905|ensembl:ENSP00000381907|ensembl:ENSP00000381911|ensembl:ENSP00000479100|ensembl:ENSP00000484960|intact:MINT-103775|uniprotkb:Q96L28|uniprotkb:D3DSH5|uniprotkb:Q99446|uniprotkb:O00564 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:kcj15_human(display_long)|uniprotkb:KCNJ15(gene name)|psi-mi:KCNJ15(display_short)|uniprotkb:KCNJ14(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 15(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.2"(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir1.3"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690189|mint:MINT-1891793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891802(identity) refseq:XP_011527862.1|refseq:XP_011527863.1|ensembl:ENSG00000157551(gene)|ensembl:ENST00000328656(transcript)|ensembl:ENST00000398930(transcript)|ensembl:ENST00000398932(transcript)|ensembl:ENST00000398934(transcript)|ensembl:ENST00000398938(transcript)|ensembl:ENST00000612702(transcript)|ensembl:ENST00000613499(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003270(Potassium channel, inwardly rectifying, Kir1.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-HSA-1296041|reactome:R-HSA-997272|refseq:XP_016883832.1|refseq:XP_016883833.1|refseq:XP_016883834.1|refseq:NP_001263365.1|refseq:NP_733933.1|refseq:NP_001263368.1|refseq:NP_001263366.1|refseq:NP_002234.2|refseq:NP_001263364.1|refseq:NP_001263367.1|refseq:NP_733932.1|refseq:XP_005261032.1|refseq:XP_006724065.1|mint:MINT-1891794(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:mint|function:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium|comment:"Stoichiometry: 1.0" figure legend:T3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:TiE/A9/tLsonRMg7/KsThkWgr8Q9606 intact-crc:29117A0059DDBE45|rigid:Piw0/znqvv9HQDcHcfq6V9gOMeM false binding-associated region:311-491(MINT-1891810)|tag:?-?(MINT-1891803) tag:?-?(MINT-1891800) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q00960 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-396905|uniprotkb:Q62684 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde2_rat(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689830|mint:MINT-1891205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891213(identity) rgd:2738|refseq:NP_036706.1|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010350"(cellular response to magnesium starvation)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904644"(cellular response to curcumin)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3JPW|rcsb pdb:3JPY|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4PE5|rcsb pdb:5B3J|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5TPZ|rcsb pdb:6CNA|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|mint:Q00960|dip:DIP-33702N|mint:MINT-1891206(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:dbOLObdhW/ts7GuZ0k8UIII99m010116 intact-crc:CCD71D4C6E3A5CF4|rigid:zBSINQCHdDEWR0Gf+QZIx3gq58w false glutathione s tranferase tag:?-?(MINT-1891218) binding-associated region:289-482(MINT-1891207) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:P35436 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689812|mint:MINT-1891135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891145(identity) refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|mint:MINT-1891136(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090 intact-crc:23632458859337C4|rigid:2MVlsl2gLvrLA+Ox9tcorV3RuGU false glutathione s tranferase tag:?-?(MINT-1891151) binding-associated region:1300-1464(MINT-1891137) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q9JM63 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-2309655|ensembl:ENSMUSP00000054356 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:kcj10_mouse(display_long)|uniprotkb:Kcnj10(gene name)|psi-mi:Kcnj10(display_short)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.1"(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689922|mint:MINT-1891099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891114(identity) refseq:NP_001034573.1|refseq:XP_006496740.2|ensembl:ENSMUSG00000044708(gene)|ensembl:ENSMUST00000056136(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0051938"(L-glutamate import)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:Q9JM63|reactome:R-MMU-1296041|reactome:R-MMU-1296067|reactome:R-MMU-997272|mint:MINT-1891100(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:xYsrr3gfPI6Dob9k78XGFz3Pp2410090 intact-crc:67CFE77C57C90D96|rigid:vZTvVYxT+NitzqwqIpVZ6YPZEfg false glutathione s tranferase tag:?-?(MINT-1891120) mutation disrupting interaction:379-379(MINT-1891101)|mutation disrupting interaction:377-377(MINT-1891103) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:O88932 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-8689883|intact:MINT-1890790|uniprotkb:Q9JK34|ensembl:ENSMUSP00000109485|ensembl:ENSMUSP00000109486|ensembl:ENSMUSP00000109487|ensembl:ENSMUSP00000109489 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:kcj15_mouse(display_long)|uniprotkb:Kcnj15(gene name)|psi-mi:Kcnj15(display_short)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 15(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.2"(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689908|mint:MINT-1890766 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1890781(identity) refseq:XP_017172374.1|refseq:NP_001258622.1|refseq:NP_001258618.1|refseq:NP_001034145.1|refseq:NP_001258624.1|refseq:NP_001258620.1|refseq:NP_062638.1|refseq:XP_006523014.1|refseq:XP_006523015.1|ensembl:ENSMUSG00000062609(gene)|ensembl:ENSMUST00000113854(transcript)|ensembl:ENSMUST00000113855(transcript)|ensembl:ENSMUST00000113856(transcript)|ensembl:ENSMUST00000113858(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003270(Potassium channel, inwardly rectifying, Kir1.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-MMU-1296041|reactome:R-MMU-997272|mint:MINT-1890767(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:mint|function:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium|comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:SmiZZRK+l8KGczxKz7kpNrUvNwM10090 intact-crc:11E12C9420917D71|rigid:c7zmU7ekb7y6zJ9sgk1DdJkG5QQ false glutathione s tranferase tag:?-?(MINT-1890787) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q62645 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-631067|uniprotkb:Q63381|uniprotkb:Q63382|uniprotkb:Q63729|uniprotkb:Q63730|ensembl:ENSRNOP00000028615 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde4_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2D(gene name synonym)|uniprotkb:Grin2d(gene name)|psi-mi:Grin2d(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-4(gene name synonym)|uniprotkb:GluN2D(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689865|mint:MINT-1891222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891230(identity) rgd:2740|refseq:NP_073634.1|ensembl:ENSRNOG00000021063(gene)|ensembl:ENSRNOT00000028615(transcript)|go:"GO:0001964"(startle response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016595"(glutamate binding)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3OEK|rcsb pdb:3OEL|rcsb pdb:3OEM|rcsb pdb:3OEN|rcsb pdb:4JWY|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|refseq:XP_008757539.1|mint:MINT-1891223(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:EI0xEBqUTBpq1D93yQqU4XLHdc810116 intact-crc:887487DB3B4867D9|rigid:3LI2BuPTncbNuGsbJ4GM57HAUPo false glutathione s tranferase tag:?-?(MINT-1891231) binding-associated region:839-1323(MINT-1891224) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99712 uniprotkb:Q63ZW7 intact:EBI-7082607|ensembl:ENSP00000331698|ensembl:ENSP00000381904|ensembl:ENSP00000381905|ensembl:ENSP00000381907|ensembl:ENSP00000381911|ensembl:ENSP00000479100|ensembl:ENSP00000484960|intact:MINT-103775|uniprotkb:Q96L28|uniprotkb:D3DSH5|uniprotkb:Q99446|uniprotkb:O00564 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 psi-mi:kcj15_human(display_long)|uniprotkb:KCNJ15(gene name)|psi-mi:KCNJ15(display_short)|uniprotkb:KCNJ14(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 15(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.2"(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir1.3"(gene name synonym) psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8689946|mint:MINT-1891868 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011527862.1|refseq:XP_011527863.1|ensembl:ENSG00000157551(gene)|ensembl:ENST00000328656(transcript)|ensembl:ENST00000398930(transcript)|ensembl:ENST00000398932(transcript)|ensembl:ENST00000398934(transcript)|ensembl:ENST00000398938(transcript)|ensembl:ENST00000612702(transcript)|ensembl:ENST00000613499(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003270(Potassium channel, inwardly rectifying, Kir1.3)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-HSA-1296041|reactome:R-HSA-997272|refseq:XP_016883832.1|refseq:XP_016883833.1|refseq:XP_016883834.1|refseq:NP_001263365.1|refseq:NP_733933.1|refseq:NP_001263368.1|refseq:NP_001263366.1|refseq:NP_002234.2|refseq:NP_001263364.1|refseq:NP_001263367.1|refseq:NP_733932.1|refseq:XP_005261032.1|refseq:XP_006724065.1|mint:MINT-1891869(identity) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891880(identity) - comment:mint|function:Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium|comment:"Stoichiometry: 1.0" comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/21 2014/10/16 rogid:TiE/A9/tLsonRMg7/KsThkWgr8Q9606 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 intact-crc:06A3F60E9CB8BAE2|rigid:Piw0/znqvv9HQDcHcfq6V9gOMeM false - glutathione s tranferase tag:?-?(MINT-1891885) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63ZW7 uniprotkb:Q00961 intact:EBI-8366894|ensembl:ENSMUSP00000049176|uniprotkb:O70471|intact:MINT-1777910|uniprotkb:Q8BPB9|uniprotkb:Q80YR8|uniprotkb:A2ADS7|uniprotkb:Q6P6J1|uniprotkb:Q5PRG3 intact:EBI-631045 psi-mi:inadl_mouse(display_long)|uniprotkb:Patj(gene name)|psi-mi:Patj(display_short)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:Cipp(gene name synonym)|uniprotkb:Inadl(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:nmde3_rat(display_long)|uniprotkb:N-methyl D-aspartate receptor subtype 2C(gene name synonym)|uniprotkb:Grin2c(gene name)|psi-mi:Grin2c(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-3(gene name synonym) psi-mi:"MI:0096"(pull down) Kurschner et al. (1998) mint:MINT-6547937|pubmed:9647694 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8690211|mint:MINT-1891847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000061859(gene)|ensembl:ENSMUST00000041284(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070160"(tight junction)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q63ZW7|refseq:NP_001005787.1|refseq:NP_001005784.1|refseq:NP_031730.1|refseq:NP_766284.2|refseq:XP_006502762.1|refseq:XP_006502763.1|refseq:XP_006502764.1|dip:DIP-41238N|mint:MINT-1891855(identity) rgd:2739|refseq:NP_036707.3|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR018884|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009611"(response to wounding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0033058"(directional locomotion)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|refseq:XP_006247769.1|refseq:XP_006247771.1|interpro:IPR028082|refseq:XP_017452475.1|refseq:XP_017452476.1|refseq:XP_017452477.1|refseq:XP_017452478.1|refseq:XP_017452479.1|refseq:XP_017452480.1|refseq:XP_017452481.1|reactome:R-RNO-438066|reactome:R-RNO-8849932|reactome:R-RNO-9609736|mint:MINT-1891848(identity) - comment:mint|function:Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/21 2014/10/16 rogid:ng9GnkEPqIrCU6BwVGwXkhOxP1810090 rogid:DNWgJGwL2992SEfrd3xZwHfJmdY10116 intact-crc:ECB191068284BB45|rigid:PUgD6givzeSnD+TQ9UAjBpiswlI false glutathione s tranferase tag:?-?(MINT-1891860) binding-associated region:975-1237(MINT-1891849) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)