#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P79832 uniprotkb:P30561 intact:EBI-958635|uniprotkb:P79831 intact:EBI-78863|uniprotkb:Q8QZX6|uniprotkb:Q8R4S3|uniprotkb:Q99P79|uniprotkb:Q9QVY1 psi-mi:arnt_oncmy(display_long)|uniprotkb:arnt(gene name)|psi-mi:arnt(display_short) psi-mi:ahr_mouse(display_long)|uniprotkb:Ahr(gene name)|psi-mi:Ahr(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pollenz et al. (1996) pubmed:8940073|imex:IM-18910 taxid:8022(oncmy)|taxid:8022("Oncorhynchus mykiss (Rainbow trout)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-958632|imex:IM-18910-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001118182.1|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|interpro:IPR013655(PAS fold-3) refseq:NP_038492.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001889"(liver development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003243"(circumferential growth involved in left ventricle morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008015"(blood circulation)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010693"(negative regulation of alkaline phosphatase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015643"(toxic substance binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0034753"(nuclear aryl hydrocarbon receptor complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048536"(spleen development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060420"(regulation of heart growth)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:0060841"(venous blood vessel development)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061009"(common bile duct development)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1904682"(cellular response to 3-methylcholanthrene)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:4M4X|rcsb pdb:5V0L|dip:DIP-222N|reactome:R-MMU-211945|reactome:R-MMU-211976|reactome:R-MMU-211981|reactome:R-MMU-8937144 - - - figure legend:7|comment:The isoform B of ARNT P79832 interacts better than isofrom a P79831.|agonist:Activation with TCDD resulted in marginal increase in interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/24 2014/10/16 rogid:4iJfOz+f98P5sZ9HQesP3mInAaU8022 rogid:N+pBJ492yievt6CTflKb8oQgqfU10090 intact-crc:5FEB65314D2FA341|rigid:K4Yp32hdRS+LzP8fNoN8F7dat5Y false 35s radiolabel:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P79832 uniprotkb:P30561 intact:EBI-958635|uniprotkb:P79831 intact:EBI-78863|uniprotkb:Q8QZX6|uniprotkb:Q8R4S3|uniprotkb:Q99P79|uniprotkb:Q9QVY1 psi-mi:arnt_oncmy(display_long)|uniprotkb:arnt(gene name)|psi-mi:arnt(display_short) psi-mi:ahr_mouse(display_long)|uniprotkb:Ahr(gene name)|psi-mi:Ahr(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pollenz et al. (1996) pubmed:8940073|imex:IM-18910 taxid:8022(oncmy)|taxid:8022("Oncorhynchus mykiss (Rainbow trout)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-958652|imex:IM-18910-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001118182.1|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|interpro:IPR013655(PAS fold-3) refseq:NP_038492.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001889"(liver development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003243"(circumferential growth involved in left ventricle morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008015"(blood circulation)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010693"(negative regulation of alkaline phosphatase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015643"(toxic substance binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0034753"(nuclear aryl hydrocarbon receptor complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048536"(spleen development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060420"(regulation of heart growth)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:0060841"(venous blood vessel development)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061009"(common bile duct development)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1904682"(cellular response to 3-methylcholanthrene)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:4M4X|rcsb pdb:5V0L|dip:DIP-222N|reactome:R-MMU-211945|reactome:R-MMU-211976|reactome:R-MMU-211981|reactome:R-MMU-8937144 - - - figure legend:7|comment:The interaction with P79832 Arnt isoform b was stronger than that with P79831 Arnt isoform a.|agonist:Activation with TCDD results in marginal increase in interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/24 2014/10/16 rogid:4iJfOz+f98P5sZ9HQesP3mInAaU8022 rogid:N+pBJ492yievt6CTflKb8oQgqfU10090 intact-crc:DFFDF026BC8E2F3E|rigid:K4Yp32hdRS+LzP8fNoN8F7dat5Y false 35s radiolabel:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)