#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P16474	uniprotkb:P14906	intact:EBI-7876|ensemblfungi:YJL034W|uniprotkb:D6VWE9	intact:EBI-16636|uniprotkb:Q08690|ensemblfungi:YOR254C|uniprotkb:D6W2V5	psi-mi:bip_yeast(display_long)|uniprotkb:KAR2(gene name)|psi-mi:KAR2(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:YJL034W(locus name)|uniprotkb:J1248(orf name)|uniprotkb:Immunoglobulin heavy chain-binding protein homolog(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein homolog(gene name synonym)	psi-mi:sec63_yeast(display_long)|uniprotkb:PTL1(gene name synonym)|uniprotkb:YOR254C(locus name)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:NPL1(gene name synonym)|uniprotkb:Sec62/63 complex 73 kDa subunit(gene name synonym)|uniprotkb:Protein NPL1(gene name synonym)	psi-mi:"MI:0091"(chromatography technology)	Brodsky et al. (1993)	pubmed:8253836|imex:IM-20100	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-966961|imex:IM-20100-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003571|ensemblfungi:YJL034W(gene)|ensemblfungi:YJL034W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|refseq:NP_012500.3|mint:P16474|dip:DIP-2392N|rcsb pdb:3QFP|rcsb pdb:3QFU|rcsb pdb:3QML|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034099"(luminal surveillance complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070880"(fungal-type cell wall beta-glucan biosynthetic process)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:3H0X	ensemblfungi:YOR254C(gene)|ensemblfungi:YOR254C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018253|interpro:IPR027137|interpro:IPR036869|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAI|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_014897.1|sgd:S000005780|dip:DIP-2396N|mint:P14906	go:"GO:0008565"(obsolete protein transporter activity)	crc64:A107BD03DF3F30D3	-	figure legend:4|comment:Addition of the Sec63 complex from the HAP column restored protein translocation activity in sec63-1 reconstituted proteoliposomes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/10	2014/10/16	rogid:+zA2eFylZ+4FgQ5zac8xx/GRV7g559292	rogid:FcVMvm368fBcw0EH918+lqynntc559292	intact-crc:9AAF2E2EC96E6A89|rigid:+h8L3axHeUu/x/wiGNxzX7af2Tg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16474	uniprotkb:P33754	intact:EBI-7876|ensemblfungi:YJL034W|uniprotkb:D6VWE9	intact:EBI-16647|ensemblfungi:YBR171W|uniprotkb:D6VQG7	psi-mi:bip_yeast(display_long)|uniprotkb:KAR2(gene name)|psi-mi:KAR2(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:YJL034W(locus name)|uniprotkb:J1248(orf name)|uniprotkb:Immunoglobulin heavy chain-binding protein homolog(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein homolog(gene name synonym)	psi-mi:sec66_yeast(display_long)|uniprotkb:SEC71(gene name synonym)|uniprotkb:YBR1232(orf name)|uniprotkb:YBR171W(locus name)|uniprotkb:SEC66(gene name)|psi-mi:SEC66(display_short)|uniprotkb:HSS1(gene name synonym)|uniprotkb:Sec62/63 complex 31.5 kDa subunit(gene name synonym)|uniprotkb:Protein HSS1(gene name synonym)	psi-mi:"MI:0091"(chromatography technology)	Brodsky et al. (1993)	pubmed:8253836|imex:IM-20100	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-966961|imex:IM-20100-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003571|ensemblfungi:YJL034W(gene)|ensemblfungi:YJL034W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|refseq:NP_012500.3|mint:P16474|dip:DIP-2392N|rcsb pdb:3QFP|rcsb pdb:3QFU|rcsb pdb:3QML|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034099"(luminal surveillance complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070880"(fungal-type cell wall beta-glucan biosynthetic process)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:3H0X	refseq:NP_009730.3|ensemblfungi:YBR171W(gene)|ensemblfungi:YBR171W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030447"(filamentous growth)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0071944"(cell periphery)|interpro:IPR018624|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|sgd:S000000375|dip:DIP-1694N|mint:P33754	go:"GO:0008565"(obsolete protein transporter activity)	crc64:A107BD03DF3F30D3	crc64:E2A8BB4994A227D4	figure legend:4|comment:Addition of the Sec63 complex from the HAP column restored protein translocation activity in sec63-1 reconstituted proteoliposomes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/10	2014/10/16	rogid:+zA2eFylZ+4FgQ5zac8xx/GRV7g559292	rogid:KvIn7euv+AwTIngwnUh/lmdLyaw559292	intact-crc:9AAF2E2EC96E6A89|rigid:+h8L3axHeUu/x/wiGNxzX7af2Tg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16474	uniprotkb:P39742	intact:EBI-7876|ensemblfungi:YJL034W|uniprotkb:D6VWE9	intact:EBI-16651|ensemblfungi:YLR292C|uniprotkb:D6VYT8	psi-mi:bip_yeast(display_long)|uniprotkb:KAR2(gene name)|psi-mi:KAR2(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:SSD1(gene name synonym)|uniprotkb:YJL034W(locus name)|uniprotkb:J1248(orf name)|uniprotkb:Immunoglobulin heavy chain-binding protein homolog(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein homolog(gene name synonym)	psi-mi:sec72_yeast(display_long)|uniprotkb:SEC67(gene name synonym)|uniprotkb:SIM2(gene name synonym)|uniprotkb:L8003.18(orf name)|uniprotkb:YLR292C(locus name)|uniprotkb:SEC72(gene name)|psi-mi:SEC72(display_short)|uniprotkb:Sec62/63 complex 23 kDa subunit(gene name synonym)	psi-mi:"MI:0091"(chromatography technology)	Brodsky et al. (1993)	pubmed:8253836|imex:IM-20100	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-966961|imex:IM-20100-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003571|ensemblfungi:YJL034W(gene)|ensemblfungi:YJL034W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|refseq:NP_012500.3|mint:P16474|dip:DIP-2392N|rcsb pdb:3QFP|rcsb pdb:3QFU|rcsb pdb:3QML|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034099"(luminal surveillance complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070880"(fungal-type cell wall beta-glucan biosynthetic process)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:3H0X	ensemblfungi:YLR292C(gene)|ensemblfungi:YLR292C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAJ|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|rcsb pdb:7KAO|rcsb pdb:7KAP|refseq:NP_013395.1|sgd:S000004283|dip:DIP-2491N|mint:P39742	go:"GO:0008565"(obsolete protein transporter activity)	crc64:A107BD03DF3F30D3	-	figure legend:4|comment:Addition of the Sec63 complex from the HAP column restored protein translocation activity in sec63-1 reconstituted proteoliposomes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/10	2014/10/16	rogid:+zA2eFylZ+4FgQ5zac8xx/GRV7g559292	rogid:R6m5FOSsQ87OrJRnqo2hkjAtqkg559292	intact-crc:9AAF2E2EC96E6A89|rigid:+h8L3axHeUu/x/wiGNxzX7af2Tg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)