#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P10826-2 uniprotkb:P28700 intact:EBI-8583223|ensembl:ENSP00000332296|intact:MINT-2768912 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:p10826-2(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Folkers et al. (1995) mint:MINT-5220419|pubmed:7565739 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8583236|mint:MINT-2774111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P10826-2(isoform-parent)|ensembl:ENSG00000077092(gene)|ensembl:ENST00000330688(transcript)|intact:EBI-2568838(isoform-parent)|mint:MINT-2774118(identity) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|mint:MINT-2774112(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|figure legend:F3C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/10 2014/10/16 rogid:SZ7/AxxaSSb8WNWvH8y4jq0Mv8g9606 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:10484BEA2F18BDD8|rigid:m2LdK4EMX5cYH0WfChpKsfGPosk false mutation increasing interaction:1-78(MINT-2774119)|mutation decreasing interaction:76-137(MINT-2774122)|binding-associated region:205-410(MINT-2774125)|mutation increasing interaction:410-448(MINT-2980682) glutathione s tranferase tag:?-?(MINT-2774116) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10826-2 uniprotkb:P03255 intact:EBI-8583223|ensembl:ENSP00000332296|intact:MINT-2768912 intact:EBI-2603114|uniprotkb:P06438|uniprotkb:Q64825|uniprotkb:Q64826 psi-mi:p10826-2(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym) psi-mi:e1a_ade05(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Folkers et al. (1995) mint:MINT-5220419|pubmed:7565739 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8583271|mint:MINT-2980686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P10826-2(isoform-parent)|ensembl:ENSG00000077092(gene)|ensembl:ENST00000330688(transcript)|intact:EBI-2568838(isoform-parent)|mint:MINT-2980693(identity) refseq:AP_000197.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR014410(Adenovirus early E1A)|rcsb pdb:2KJE|rcsb pdb:2R7G|rcsb pdb:6H6D|rcsb pdb:6H6H|go:"GO:0042025"(host cell nucleus)|dip:DIP-40736N|mint:P03255|mint:MINT-2980687(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|figure legend:F4C|figure legend:F3C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/10 2014/10/16 rogid:SZ7/AxxaSSb8WNWvH8y4jq0Mv8g9606 rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285 intact-crc:5D243247DD59EF16|rigid:gBYXEFA95qOsTy54cLprQ2gJoSE false mutation increasing interaction:410-448(MINT-2980705)|mutation increasing interaction:1-78(MINT-2980699)|binding-associated region:205-410(MINT-2980697)|mutation decreasing interaction:76-137(MINT-2980702) glutathione s tranferase tag:?-?(MINT-2980690)|binding-associated region:1-177(MINT-2980710) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10826-2 uniprotkb:P03255 intact:EBI-8583223|ensembl:ENSP00000332296|intact:MINT-2768912 intact:EBI-2603114|uniprotkb:P06438|uniprotkb:Q64825|uniprotkb:Q64826 psi-mi:p10826-2(display_long)|uniprotkb:RARB(gene name)|psi-mi:RARB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HBV-activated protein(gene name synonym)|uniprotkb:NR1B2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 2(gene name synonym)|uniprotkb:RAR-epsilon(gene name synonym) psi-mi:e1a_ade05(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Folkers et al. (1995) mint:MINT-5220419|pubmed:7565739 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8583315|mint:MINT-2767859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P10826-2(isoform-parent)|ensembl:ENSG00000077092(gene)|ensembl:ENST00000330688(transcript)|intact:EBI-2568838(isoform-parent)|mint:MINT-2767889(identity) refseq:AP_000197.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR014410(Adenovirus early E1A)|rcsb pdb:2KJE|rcsb pdb:2R7G|rcsb pdb:6H6D|rcsb pdb:6H6H|go:"GO:0042025"(host cell nucleus)|dip:DIP-40736N|mint:P03255|mint:MINT-2767885(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2006/07/10 2014/10/16 rogid:SZ7/AxxaSSb8WNWvH8y4jq0Mv8g9606 rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285 intact-crc:359423B9EDBBE64B|rigid:gBYXEFA95qOsTy54cLprQ2gJoSE false ha tag:?-?(MINT-2882772) - 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)