#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96C90	uniprotkb:O75116	intact:EBI-7009703|ensembl:ENSP00000310117|uniprotkb:Q504S7|uniprotkb:Q7KZD7|intact:MINT-3051633	intact:EBI-366288|uniprotkb:Q9UQN5|ensembl:ENSP00000317985|uniprotkb:Q53QZ0|uniprotkb:Q53SJ7	psi-mi:pp14b_human(display_long)|uniprotkb:PPP1R14B(gene name)|psi-mi:PPP1R14B(display_short)|uniprotkb:PLCB3N(gene name synonym)|uniprotkb:PNG(gene name synonym)|uniprotkb:Phospholipase C-beta-3 neighbouring gene protein(gene name synonym)	psi-mi:rock2_human(display_long)|uniprotkb:ROCK2(gene name)|psi-mi:ROCK2(display_short)|uniprotkb:KIAA0619(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase II(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 2(gene name synonym)|uniprotkb:p164 ROCK-2(gene name synonym)|uniprotkb:Rho kinase 2(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	El-Toukhy et al. (2006)	pubmed:17022978|imex:IM-10907|mint:MINT-5219181	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009696|mint:MINT-3374782|imex:IM-10907-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173457(gene)|ensembl:ENST00000309318(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0045087"(innate immune response)|interpro:IPR008025(PKC-activated phosphatase-1 inhibitor)|interpro:IPR036658|mint:Q96C90|refseq:NP_619634.1|mint:MINT-3374784(identity)	go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037311|mint:O75116|rcsb pdb:4L6Q|rcsb pdb:4WOT|rcsb pdb:5U7Q|rcsb pdb:5U7R|rcsb pdb:6ED6|rcsb pdb:6P5M|rcsb pdb:6P5P|rcsb pdb:7JNT|rcsb pdb:7JOV|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5627117|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013407|reactome:R-HSA-9013422|reactome:R-HSA-9679191|refseq:NP_004841.2|ensembl:ENSG00000134318(gene)|ensembl:ENST00000315872(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|refseq:NP_001308572.1|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0150033"(negative regulation of protein localization to lysosome)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|mint:MINT-3374783(identity)	-	comment:mint|function:Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated	-	figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/17	2014/10/16	rogid:iixNb4N7JQxvJuryne7vDkTSfUc9606	rogid:iCgqC5U/DXAzOEq6edMtL6ncK7U9606	intact-crc:238851E8703EC35F|rigid:Ui+npwpdgsR4cW7F4dFRJ1DuBkY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96C90	uniprotkb:P36873	intact:EBI-7009703|ensembl:ENSP00000310117|uniprotkb:Q504S7|uniprotkb:Q7KZD7|intact:MINT-3051633	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:pp14b_human(display_long)|uniprotkb:PPP1R14B(gene name)|psi-mi:PPP1R14B(display_short)|uniprotkb:PLCB3N(gene name synonym)|uniprotkb:PNG(gene name synonym)|uniprotkb:Phospholipase C-beta-3 neighbouring gene protein(gene name synonym)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	El-Toukhy et al. (2006)	pubmed:17022978|imex:IM-10907|mint:MINT-5219181	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7009737|mint:MINT-3374798|imex:IM-10907-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173457(gene)|ensembl:ENST00000309318(transcript)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0045087"(innate immune response)|interpro:IPR008025(PKC-activated phosphatase-1 inhibitor)|interpro:IPR036658|mint:Q96C90|refseq:NP_619634.1|mint:MINT-3374799(identity)	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N|mint:MINT-3374804(identity)	-	comment:mint|function:Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:Human Up_Id for PP1c AND PHI-1 were used instead of the chicken ones.|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-gizzard)|taxid:9031(Chicken gizzard)	-	2006/10/17	2014/10/16	rogid:iixNb4N7JQxvJuryne7vDkTSfUc9606	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	intact-crc:0B9A5263875895BC|rigid:Xj9PagRQ1EPpS81SbTJlTyevDME	false	-	-	-	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)