#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14517 uniprotkb:Q9Z2Y3 intact:EBI-1171918|ensembl:ENSP00000406229 intact:EBI-396980|uniprotkb:Q8K3E1|uniprotkb:Q8K4M8|uniprotkb:Q9Z0E9|uniprotkb:Q9Z216|ensembl:ENSMUSP00000079026 psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:home1_mouse(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Vesl1(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980075|mint:MINT-3370128|imex:IM-11304-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370129(identity) refseq:NP_036112.1|refseq:NP_671705.2|refseq:NP_687036.1|refseq:NP_001271118.1|refseq:NP_001334527.1|ensembl:ENSMUSG00000007617(gene)|ensembl:ENSMUST00000080127(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9Z2Y3|reactome:R-MMU-6794361|mint:MINT-3370130(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 rogid:aOI1ZRXwOjFH9a3s6Jf1FNfMdiA10090 intact-crc:0B6EFA25D376071F|rigid:YqfgmTVVdjOISIQUvMs0EgOg07o false binding-associated region:4203-4588(MINT-3370137)|his tag:?-?(MINT-3370131) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q99JP6 uniprotkb:Q14517 intact:EBI-6272061|ensembl:ENSMUSP00000117033|uniprotkb:D3Z6N9|uniprotkb:Q9Z215 intact:EBI-1171918|ensembl:ENSP00000406229 psi-mi:home3_mouse(display_long)|uniprotkb:Homer3(gene name)|psi-mi:Homer3(display_short) psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980096|mint:MINT-3370150|imex:IM-11304-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003573(gene)|ensembl:ENSMUST00000140212(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q99JP6|reactome:R-MMU-6794361|refseq:NP_001139625.1|refseq:NP_036114.2|mint:MINT-3370161(identity) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370151(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:7IOPI8VTi6aKK/I0tl4AiUUIXIU10090 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 intact-crc:51FD89778DB7C5D1|rigid:Tgdo5VORGhDK+zWu1jnDzn3Te+U false - binding-associated region:4203-4588(MINT-3370158)|his tag:?-?(MINT-3370152) 1 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28738 uniprotkb:Q14517 intact:EBI-2506834|uniprotkb:Q6NXI9|ensembl:ENSMUSP00000028102|uniprotkb:Q9Z2F8 intact:EBI-1171918|ensembl:ENSP00000406229 psi-mi:kif5c_mouse(display_long)|uniprotkb:Kif5c(gene name)|psi-mi:Kif5c(display_short)|uniprotkb:Nkhc2(gene name synonym)|uniprotkb:Kinesin heavy chain neuron-specific 2(gene name synonym) psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980131|mint:MINT-3370187|imex:IM-11304-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026764(gene)|ensembl:ENSMUST00000028102(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098964"(anterograde dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0150034"(distal axon)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:P28738|rcsb pdb:1VFV|rcsb pdb:1VFW|rcsb pdb:1VFX|rcsb pdb:1VFZ|rcsb pdb:3J6H|rcsb pdb:3WRD|rcsb pdb:3X2T|rcsb pdb:5HLE|refseq:NP_032475.2|mint:MINT-3370198(identity) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370188(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:GbPyKDztqPG8BP2+44k3TXPuI/010090 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 intact-crc:FB3CFA5D3817FAFA|rigid:dWVeWAkc5M9t4JClGn4cQeDTtbg false - binding-associated region:4203-4588(MINT-3370195)|his tag:?-?(MINT-3370189) 1 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O88447 uniprotkb:Q14517 intact:EBI-301550 intact:EBI-1171918|ensembl:ENSP00000406229 psi-mi:klc1_mouse(display_long)|uniprotkb:Klc1(gene name)|psi-mi:Klc1(display_short)|uniprotkb:Kns2(gene name synonym) psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980172|mint:MINT-3370225|imex:IM-11304-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O88447|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043227"(membrane-bounded organelle)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:6FUZ|rcsb pdb:6FV0|reactome:R-MMU-2132295|reactome:R-MMU-5625970|reactome:R-MMU-6811434|reactome:R-MMU-983189|dip:DIP-31520N|mint:MINT-3370236(identity) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370226(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:YFYhenefPpzqNvaDB3e6plPlGQo10090 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 intact-crc:89B3F0FED096F5B9|rigid:muYy7cZHjOQW5ObDPd0ms0VQmw4 false - his tag:?-?(MINT-3370227)|binding-associated region:4203-4588(MINT-3370233) 1 1 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14517 uniprotkb:O88448 intact:EBI-1171918|ensembl:ENSP00000406229 intact:EBI-301558 psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:klc2_mouse(display_long)|uniprotkb:Klc2(gene name)|psi-mi:Klc2(display_short) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980152|mint:MINT-3370206|imex:IM-11304-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370207(identity) mint:O88448|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|rcsb pdb:3ZFW|rcsb pdb:5FJY|rcsb pdb:6EJN|reactome:R-MMU-2132295|reactome:R-MMU-5625970|reactome:R-MMU-6811434|reactome:R-MMU-983189|dip:DIP-31518N|mint:MINT-3370217(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 rogid:g0zmL5gh0ehRJnJSpKFQpe7Xcps10090 intact-crc:ECEC2EFC43DDFF4B|rigid:/58gfIYhrdqrQ/q0GV5N19UmE70 false his tag:?-?(MINT-3370208)|binding-associated region:4203-4588(MINT-3370214) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9QXA3 uniprotkb:Q99JP6 intact:EBI-6980218|intact:MINT-3370348 intact:EBI-6272061|ensembl:ENSMUSP00000117033|uniprotkb:D3Z6N9|uniprotkb:Q9Z215 psi-mi:q9qxa3_mouse(display_long)|uniprotkb:Fath(gene name synonym)|uniprotkb:Fat1(gene name)|psi-mi:Fat1(display_short)|uniprotkb:mfat1(gene name synonym) psi-mi:home3_mouse(display_long)|uniprotkb:Homer3(gene name)|psi-mi:Homer3(display_short) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980212|mint:MINT-3370244|imex:IM-11304-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR000742(EGF-like, type 3)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0031252"(cell leading edge)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|mint:Q9QXA3|dip:DIP-42865N|mint:MINT-3370245(identity) ensembl:ENSMUSG00000003573(gene)|ensembl:ENSMUST00000140212(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q99JP6|reactome:R-MMU-6794361|refseq:NP_001139625.1|refseq:NP_036114.2|mint:MINT-3370255(identity) - comment:"fragmentation type: fragment"|comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:fC+UbQdxz2HCkmn2YUVye5XgrhE10090 rogid:7IOPI8VTi6aKK/I0tl4AiUUIXIU10090 intact-crc:1F8529641FDB02DF|rigid:hk2danss++F3HMbRIVAZQGkOEVM false - glutathione s tranferase tag:?-?(MINT-3370262) 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14517 uniprotkb:Q99JP6 intact:EBI-1171918|ensembl:ENSP00000406229 intact:EBI-6272061|ensembl:ENSMUSP00000117033|uniprotkb:D3Z6N9|uniprotkb:Q9Z215 psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:home3_mouse(display_long)|uniprotkb:Homer3(gene name)|psi-mi:Homer3(display_short) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-6980192|mint:MINT-3370325|imex:IM-11304-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370326(identity) ensembl:ENSMUSG00000003573(gene)|ensembl:ENSMUST00000140212(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q99JP6|reactome:R-MMU-6794361|refseq:NP_001139625.1|refseq:NP_036114.2|mint:MINT-3370336(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 rogid:7IOPI8VTi6aKK/I0tl4AiUUIXIU10090 intact-crc:6DBFA91FB337F4EA|rigid:Tgdo5VORGhDK+zWu1jnDzn3Te+U false binding-associated region:4203-4588(MINT-3370333)|glutathione s tranferase tag:?-?(MINT-3370327) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q14517 uniprotkb:Q9NSC5 intact:EBI-1171918|ensembl:ENSP00000406229 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6980262|mint:MINT-3370268|imex:IM-11304-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370269(identity) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|mint:MINT-3370279(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:908E0B561A65C4DA|rigid:DJqdGEVRQBHRvcqEK0q8oMfVzBU false binding-associated region:4203-4588(MINT-3370276)|his tag:?-?(MINT-3370270) glutathione s tranferase tag:?-?(MINT-3370281) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86YM7 uniprotkb:Q14517 intact:EBI-746815|uniprotkb:O96003|uniprotkb:Q86YM5|uniprotkb:B2R688|ensembl:ENSP00000334382 intact:EBI-1171918|ensembl:ENSP00000406229 psi-mi:home1_human(display_long)|uniprotkb:HOMER1(gene name)|psi-mi:HOMER1(display_short)|uniprotkb:SYN47(gene name synonym) psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:"MI:0096"(pull down) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6980302|mint:MINT-3370381|imex:IM-11304-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001264006.1|refseq:NP_001264007.1|refseq:NP_004263.1|go:"GO:0005886"(plasma membrane)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001257"(regulation of cation channel activity)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q86YM7|reactome:R-HSA-6794361|go:"GO:2001256"(regulation of store-operated calcium entry)|ensembl:ENSG00000152413(gene)|ensembl:ENST00000334082(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|mint:MINT-3370392(identity) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370382(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:ZKKSd3cgSM6/8RKLxorPAHaudLA9606 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 intact-crc:DBEB9152B3F264F5|rigid:LFYvUlZTRPzVEwFbcTZZbDsny0k false glutathione s tranferase tag:?-?(MINT-3370394) his tag:?-?(MINT-3370383)|binding-associated region:4203-4588(MINT-3370389) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14517 uniprotkb:Q9NSC5 intact:EBI-1171918|ensembl:ENSP00000406229 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0428"(imaging technique) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-6980386|mint:MINT-3370401|imex:IM-11304-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370402(identity) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|mint:MINT-3370412(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/09/29 2014/10/16 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:C5F98150CA25D5AC|rigid:DJqdGEVRQBHRvcqEK0q8oMfVzBU false tag:?-?(MINT-3370403) ha tag:?-?(MINT-3370421) 1 1 psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:Q14517 uniprotkb:Q9NSC5 intact:EBI-1171918|ensembl:ENSP00000406229 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6980427|mint:MINT-3370427|imex:IM-11304-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370428(identity) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|mint:MINT-3370438(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 intact-crc:7083AAF8BEBCCBC6|rigid:DJqdGEVRQBHRvcqEK0q8oMfVzBU false his tag:?-?(MINT-3370429)|binding-associated region:4203-4588(MINT-3370435)|necessary binding region:4437-4444(MINT-3370447) glutathione s tranferase tag:?-?(MINT-3370440) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N8S7 uniprotkb:Q14517 intact:EBI-2834410|uniprotkb:Q5VTQ9|uniprotkb:Q9UFB8|uniprotkb:Q9NVF3|uniprotkb:Q502W5|uniprotkb:Q5T5M7|uniprotkb:Q5VTR0|uniprotkb:D0PQI2|ensembl:ENSP00000355809 intact:EBI-1171918|ensembl:ENSP00000406229 psi-mi:enah_human(display_long)|uniprotkb:ENAH(gene name)|psi-mi:ENAH(display_short)|uniprotkb:MENA(gene name synonym) psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6980492|mint:MINT-3370478|imex:IM-11304-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008493.1|refseq:NP_060682.2|ensembl:ENSG00000154380(gene)|ensembl:ENST00000366844(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|mint:Q8N8S7|rcsb pdb:2HO2|rcsb pdb:2IYB|rcsb pdb:2XQN|rcsb pdb:4MY6|rcsb pdb:5N91|rcsb pdb:5N9C|rcsb pdb:5N9P|rcsb pdb:5NAJ|rcsb pdb:5NBF|rcsb pdb:5NBX|go:"GO:0005925"(focal adhesion)|rcsb pdb:5NC2|rcsb pdb:5NC7|rcsb pdb:5NCF|rcsb pdb:5NCG|rcsb pdb:5NCP|rcsb pdb:5ND0|rcsb pdb:5NDU|rcsb pdb:5NEG|rcsb pdb:6RCF|rcsb pdb:6RCJ|rcsb pdb:6RD2|rcsb pdb:6XVT|rcsb pdb:6XXR|rcsb pdb:7A5M|rcsb pdb:7AKI|reactome:R-HSA-202433|reactome:R-HSA-376176|mint:MINT-3370479(identity) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370486(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:FxcMlDgO3bbl9NRD/z+fDOcdLic9606 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 intact-crc:FDC75D5A18FFD2CE|rigid:vHHVGi/1NI3onaBqjGHBY5HQUpw false glutathione s tranferase tag:?-?(MINT-3370481) binding-associated region:4203-4588(MINT-3370493)|necessary binding region:4437-4444(MINT-3370496)|his tag:?-?(MINT-3370487) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NSC5 uniprotkb:Q14517 intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10 intact:EBI-1171918|ensembl:ENSP00000406229 psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short) psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6980462|mint:MINT-3370454|imex:IM-11304-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|mint:MINT-3370455(identity) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370462(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 intact-crc:9CA545B8BAA40CFA|rigid:DJqdGEVRQBHRvcqEK0q8oMfVzBU false glutathione s tranferase tag:?-?(MINT-3370457) mutation disrupting interaction:4438-4438(MINT-3370472)|his tag:?-?(MINT-3370463)|binding-associated region:4203-4588(MINT-3370469) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14517 uniprotkb:Q8N8S7 intact:EBI-1171918|ensembl:ENSP00000406229 intact:EBI-2834410|uniprotkb:Q5VTQ9|uniprotkb:Q9UFB8|uniprotkb:Q9NVF3|uniprotkb:Q502W5|uniprotkb:Q5T5M7|uniprotkb:Q5VTR0|uniprotkb:D0PQI2|ensembl:ENSP00000355809 psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym) psi-mi:enah_human(display_long)|uniprotkb:ENAH(gene name)|psi-mi:ENAH(display_short)|uniprotkb:MENA(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schreiner et al. (2006) pubmed:16979624|imex:IM-11304|mint:MINT-5219108 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-6980521|mint:MINT-3370511|imex:IM-11304-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)|mint:MINT-3370512(identity) refseq:NP_001008493.1|refseq:NP_060682.2|ensembl:ENSG00000154380(gene)|ensembl:ENST00000366844(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|mint:Q8N8S7|rcsb pdb:2HO2|rcsb pdb:2IYB|rcsb pdb:2XQN|rcsb pdb:4MY6|rcsb pdb:5N91|rcsb pdb:5N9C|rcsb pdb:5N9P|rcsb pdb:5NAJ|rcsb pdb:5NBF|rcsb pdb:5NBX|go:"GO:0005925"(focal adhesion)|rcsb pdb:5NC2|rcsb pdb:5NC7|rcsb pdb:5NCF|rcsb pdb:5NCG|rcsb pdb:5NCP|rcsb pdb:5ND0|rcsb pdb:5NDU|rcsb pdb:5NEG|rcsb pdb:6RCF|rcsb pdb:6RCJ|rcsb pdb:6RD2|rcsb pdb:6XVT|rcsb pdb:6XXR|rcsb pdb:7A5M|rcsb pdb:7AKI|reactome:R-HSA-202433|reactome:R-HSA-376176|mint:MINT-3370525(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/29 2014/10/16 rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606 rogid:FxcMlDgO3bbl9NRD/z+fDOcdLic9606 intact-crc:3632D2090C43E296|rigid:vHHVGi/1NI3onaBqjGHBY5HQUpw false his tag:?-?(MINT-3370513)|mutation disrupting interaction:4438-4438(MINT-3370522)|binding-associated region:4203-4588(MINT-3370519) glutathione s tranferase tag:?-?(MINT-3370527) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)