#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51637	uniprotkb:Q60634	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-529748|uniprotkb:Q6NS75|uniprotkb:Q5SS82|ensembl:ENSMUSP00000072136	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:flot2_mouse(display_long)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Flot2(gene name)|psi-mi:Flot2(display_short)|uniprotkb:Esa1(gene name synonym)|uniprotkb:M17s1(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1 homolog(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Willmann et al. (2006)	mint:MINT-5218994|pubmed:16932745|imex:IM-11439	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8621600|mint:MINT-2982995|imex:IM-11439-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N|mint:MINT-2982996(identity)	refseq:NP_001271156.1|refseq:NP_001271157.1|refseq:NP_001035493.1|refseq:NP_032054.1|refseq:XP_006532255.1|refseq:XP_006532256.1|ensembl:ENSMUSG00000061981(gene)|ensembl:ENSMUST00000072289(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q60634|rcsb pdb:1WIN|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-8849932|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9696264|reactome:R-MMU-9696273|mint:MINT-2982997(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/18	2014/10/16	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jZiEDFJRD3Irrji4NTEpDUzUVeY10090	intact-crc:B730ABBD4B72E2CB|rigid:FLLiEu8LpW7d6YnHNJSRaw0lgMg	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09690	uniprotkb:Q62165	intact:EBI-8621613|ensembl:ENSMUSP00000047270|intact:MINT-2983098|uniprotkb:Q5F292	intact:EBI-2878952|uniprotkb:Q61094|uniprotkb:Q61141|uniprotkb:Q61497|ensembl:ENSMUSP00000079294|ensembl:ENSMUSP00000128531|ensembl:ENSMUSP00000130626|ensembl:ENSMUSP00000142109	psi-mi:achb_mouse(display_long)|uniprotkb:Chrnb1(gene name)|psi-mi:Chrnb1(display_short)|uniprotkb:Acrb(gene name synonym)	psi-mi:dag1_mouse(display_long)|uniprotkb:Dag1(gene name)|psi-mi:Dag1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Willmann et al. (2006)	mint:MINT-5218994|pubmed:16932745|imex:IM-11439	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8621644|mint:MINT-2983155|imex:IM-11439-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041189(gene)|ensembl:ENSMUST00000045971(transcript)|go:"GO:0001941"(postsynaptic membrane organization)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006812"(cation transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0015267"(channel activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0055001"(muscle cell development)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|mint:P09690|refseq:NP_033731.3|mint:MINT-2983156(identity)	refseq:NP_001263410.1|refseq:NP_001263411.1|refseq:NP_001263414.1|refseq:NP_001263415.1|refseq:NP_001263421.1|refseq:NP_001263422.1|refseq:NP_034147.1|refseq:XP_006511699.1|ensembl:ENSMUSG00000039952(gene)|ensembl:ENSMUST00000080435(transcript)|ensembl:ENSMUST00000166905(transcript)|ensembl:ENSMUST00000171412(transcript)|ensembl:ENSMUST00000191899(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007411"(axon guidance)|go:"GO:0007568"(aging)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0015631"(tubulin binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016340"(calcium-dependent cell-matrix adhesion)|go:"GO:0017166"(vinculin binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0021675"(nerve development)|go:"GO:0021682"(nerve maturation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0070938"(contractile ring)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0071711"(basement membrane organization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015919(Cadherin-like)|interpro:IPR027468|interpro:IPR030398|interpro:IPR041631|mint:Q62165|rcsb pdb:1U2C|rcsb pdb:4WIQ|rcsb pdb:5N30|rcsb pdb:5N4H|reactome:R-MMU-3000178|reactome:R-MMU-5173105|reactome:R-MMU-9010553|mint:MINT-2983159(identity)	-	comment:mint|function:After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/18	2014/10/16	rogid:Ni8CSbcLoYO+Yf0IrkHhcNrTpas10090	rogid:eNEkukP8dp54BA24gR5sbtHLO6g10090	intact-crc:2FED0CA67129AFEE|rigid:SqRT+4XOkVZESwf+uZJgbH3evcY	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09690	uniprotkb:O15146	intact:EBI-8621613|ensembl:ENSMUSP00000047270|intact:MINT-2983098|uniprotkb:Q5F292	intact:EBI-6423196|uniprotkb:Q32MJ8|uniprotkb:Q5VZW8|uniprotkb:Q32MJ9|uniprotkb:Q5VZW7|ensembl:ENSP00000363571	psi-mi:achb_mouse(display_long)|uniprotkb:Chrnb1(gene name)|psi-mi:Chrnb1(display_short)|uniprotkb:Acrb(gene name synonym)	psi-mi:musk_human(display_long)|uniprotkb:MUSK(gene name)|psi-mi:MUSK(display_short)|uniprotkb:Muscle-specific tyrosine-protein kinase receptor(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Willmann et al. (2006)	mint:MINT-5218994|pubmed:16932745|imex:IM-11439	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8621644|mint:MINT-2983155|imex:IM-11439-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041189(gene)|ensembl:ENSMUST00000045971(transcript)|go:"GO:0001941"(postsynaptic membrane organization)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006812"(cation transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0015267"(channel activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0055001"(muscle cell development)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|mint:P09690|refseq:NP_033731.3|mint:MINT-2983156(identity)	refseq:NP_001159752.1|refseq:NP_001159753.1|refseq:NP_005583.1|ensembl:ENSG00000030304(gene)|ensembl:ENST00000374448(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007613"(memory)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:2000541"(positive regulation of protein geranylgeranylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020067|interpro:IPR020635|interpro:IPR036179|interpro:IPR036790|mint:O15146|reactome:R-HSA-3000178|mint:MINT-2983157(identity)	-	comment:mint|function:After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F5D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/18	2014/10/16	rogid:Ni8CSbcLoYO+Yf0IrkHhcNrTpas10090	rogid:+98T74K0J0OlFdo2neccLXgX8hA9606	intact-crc:2FED0CA67129AFEE|rigid:SqRT+4XOkVZESwf+uZJgbH3evcY	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09690	uniprotkb:Q9D2N4-2	intact:EBI-8621613|ensembl:ENSMUSP00000047270|intact:MINT-2983098|uniprotkb:Q5F292	intact:EBI-8621682|intact:MINT-197210	psi-mi:achb_mouse(display_long)|uniprotkb:Chrnb1(gene name)|psi-mi:Chrnb1(display_short)|uniprotkb:Acrb(gene name synonym)	psi-mi:q9d2n4-2(display_long)|uniprotkb:Dtna(gene name)|psi-mi:Dtna(display_short)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dtn(gene name synonym)|uniprotkb:Alpha-DB1(isoform synonym)|uniprotkb:Alpha-dystrobrevin-1(isoform synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Willmann et al. (2006)	mint:MINT-5218994|pubmed:16932745|imex:IM-11439	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8621644|mint:MINT-2983155|imex:IM-11439-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041189(gene)|ensembl:ENSMUST00000045971(transcript)|go:"GO:0001941"(postsynaptic membrane organization)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006812"(cation transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0015267"(channel activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0055001"(muscle cell development)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|mint:P09690|refseq:NP_033731.3|mint:MINT-2983156(identity)	intact:EBI-296019(isoform-parent)|mint:MINT-2983160(identity)	-	comment:mint|function:After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F5D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/18	2014/10/16	rogid:Ni8CSbcLoYO+Yf0IrkHhcNrTpas10090	rogid:/WaH9ChSsw4ZMqps8iY1aHVjqAs10090	intact-crc:2FED0CA67129AFEE|rigid:SqRT+4XOkVZESwf+uZJgbH3evcY	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09690	uniprotkb:P12672	intact:EBI-8621613|ensembl:ENSMUSP00000047270|intact:MINT-2983098|uniprotkb:Q5F292	intact:EBI-8621651|ensembl:ENSMUSP00000054150|intact:MINT-2983138|uniprotkb:Q2M2N6	psi-mi:achb_mouse(display_long)|uniprotkb:Chrnb1(gene name)|psi-mi:Chrnb1(display_short)|uniprotkb:Acrb(gene name synonym)	psi-mi:rapsn_mouse(display_long)|uniprotkb:Rapsn(gene name)|psi-mi:Rapsn(display_short)|uniprotkb:Acetylcholine receptor-associated 43 kDa protein(gene name synonym)|uniprotkb:43 kDa postsynaptic protein(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Willmann et al. (2006)	mint:MINT-5218994|pubmed:16932745|imex:IM-11439	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8621644|mint:MINT-2983155|imex:IM-11439-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041189(gene)|ensembl:ENSMUST00000045971(transcript)|go:"GO:0001941"(postsynaptic membrane organization)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006812"(cation transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0015267"(channel activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015464"(acetylcholine receptor activity)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050877"(nervous system process)|go:"GO:0055001"(muscle cell development)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|mint:P09690|refseq:NP_033731.3|mint:MINT-2983156(identity)	ensembl:ENSMUSG00000002104(gene)|ensembl:ENSMUST00000050323(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0016020"(membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1901626"(regulation of postsynaptic membrane organization)|go:"GO:1903540"(establishment of protein localization to postsynaptic membrane)|interpro:IPR001237(43 kDa postsynaptic protein)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018293|interpro:IPR019568|interpro:IPR019734|interpro:IPR041617|mint:P12672|refseq:NP_033049.2|mint:MINT-2983158(identity)	-	comment:mint|function:After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane|comment:"Stoichiometry: 1.0"	comment:mint|function:Thought to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin|comment:"Stoichiometry: 1.0"	figure legend:F5D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/18	2014/10/16	rogid:Ni8CSbcLoYO+Yf0IrkHhcNrTpas10090	rogid:qYuBDHu9BT16g7HMog8lTkSds8A10090	intact-crc:2FED0CA67129AFEE|rigid:SqRT+4XOkVZESwf+uZJgbH3evcY	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)