#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q63648 uniprotkb:P62142 intact:EBI-1013682 intact:EBI-352326|ensembl:ENSRNOP00000006190|uniprotkb:P37140 psi-mi:merl_rat(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Nf2(gene name)|psi-mi:Nf2(display_short) psi-mi:pp1b_rat(display_long)|uniprotkb:Ppp1cb(gene name)|psi-mi:Ppp1cb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jin et al. (2006) imex:IM-14409|pubmed:16885985 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1013717|imex:IM-14409-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001707"(mesoderm formation)|rgd:3169|refseq:NP_037325.1|interpro:IPR019749|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|reactome:R-RNO-2029482|reactome:R-RNO-5627123|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789 ensembl:ENSRNOG00000004612(gene)|ensembl:ENSRNOT00000006190(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|rgd:3376|refseq:NP_037197.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|reactome:R-RNO-2565942|reactome:R-RNO-5625740|reactome:R-RNO-5627123|reactome:R-RNO-5673000|go:"GO:0032922"(circadian regulation of gene expression)|refseq:XP_008762727.1 go:"GO:0042127"(regulation of cell population proliferation) - - figure legend:2A|comment:The PP1 delta catalytic subunit is also named the beta catalytic subunit.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rt4_d6p2t)|taxid:10116(Rattus norvegicus Schwann cell, immature) - 2006/08/25 2014/10/16 rogid:CI6QpTPk+DPW/55bQuXqdduGQzM10116 rogid:VtNJVyimeiEuRDDWtGswTqoSOH810116 intact-crc:CDE2859A40EC4266|rigid:UiqlHoXffXEzs/IOhUhHqfR7O4o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q63648 uniprotkb:Q10728 intact:EBI-1013682 intact:EBI-918263|uniprotkb:Q62937|uniprotkb:Q9WU33 psi-mi:merl_rat(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Nf2(gene name)|psi-mi:Nf2(display_short) psi-mi:mypt1_rat(display_long)|uniprotkb:Ppp1r12a(gene name)|psi-mi:Ppp1r12a(display_short)|uniprotkb:Mbs(gene name synonym)|uniprotkb:Mypt1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)|uniprotkb:MBSP(gene name synonym)|uniprotkb:Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110(gene name synonym)|uniprotkb:Protein phosphatase subunit 1M(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jin et al. (2006) imex:IM-14409|pubmed:16885985 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1013717|imex:IM-14409-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001707"(mesoderm formation)|rgd:3169|refseq:NP_037325.1|interpro:IPR019749|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|reactome:R-RNO-2029482|reactome:R-RNO-5627123|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789 rgd:620013|refseq:NP_446342.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031775|refseq:XP_006241377.1|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR036770|reactome:R-RNO-2565942|reactome:R-RNO-5625740|reactome:R-RNO-5627123|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex) go:"GO:0042127"(regulation of cell population proliferation) - - figure legend:2A|comment:The PP1 delta catalytic subunit is also named the beta catalytic subunit.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rt4_d6p2t)|taxid:10116(Rattus norvegicus Schwann cell, immature) - 2006/08/25 2014/10/16 rogid:CI6QpTPk+DPW/55bQuXqdduGQzM10116 rogid:C2cW3Wgc4JZQGtDsP1NgRkzEr1s10116 intact-crc:CDE2859A40EC4266|rigid:UiqlHoXffXEzs/IOhUhHqfR7O4o false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35240 uniprotkb:Q10728 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 intact:EBI-918263|uniprotkb:Q62937|uniprotkb:Q9WU33 psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:mypt1_rat(display_long)|uniprotkb:Ppp1r12a(gene name)|psi-mi:Ppp1r12a(display_short)|uniprotkb:Mbs(gene name synonym)|uniprotkb:Mypt1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)|uniprotkb:MBSP(gene name synonym)|uniprotkb:Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110(gene name synonym)|uniprotkb:Protein phosphatase subunit 1M(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jin et al. (2006) imex:IM-14409|pubmed:16885985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1014791|imex:IM-14409-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N rgd:620013|refseq:NP_446342.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031775|refseq:XP_006241377.1|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR036770|reactome:R-RNO-2565942|reactome:R-RNO-5625740|reactome:R-RNO-5627123|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex) go:"GO:0042127"(regulation of cell population proliferation) - - figure legend:2 C|comment:MYPT-1 preferred the phosphorylated form of merlin as it coprecipitated in greated quantities with the wild-type merlin of ser518asp mutant than the ser518ala non-phosphorylatable mutant merlin.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rt4_d6p2t)|taxid:10116(Rattus norvegicus Schwann cell, immature) - 2006/08/25 2014/10/16 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:C2cW3Wgc4JZQGtDsP1NgRkzEr1s10116 intact-crc:9BA4BDB1AF702C34|rigid:/8NGAI7JnABouIG7sce2ql9Qfls false mutation decreasing interaction:518-518 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P46662 uniprotkb:P62141 intact:EBI-644586|uniprotkb:Q8BR03|ensembl:ENSMUSP00000105536 intact:EBI-352338|uniprotkb:P37140|uniprotkb:Q3TBE5|uniprotkb:Q3TL90|uniprotkb:Q542E7|uniprotkb:Q8C285|uniprotkb:Q9DBY2|ensembl:ENSMUSP00000015100|ensembl:ENSMUSP00000144047 psi-mi:merl_mouse(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Nf2(gene name)|psi-mi:Nf2(display_short)|uniprotkb:Nf-2(gene name synonym) psi-mi:pp1b_mouse(display_long)|uniprotkb:Ppp1cb(gene name)|psi-mi:Ppp1cb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jin et al. (2006) imex:IM-14409|pubmed:16885985 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1014356|imex:IM-14409-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035028.2|refseq:XP_006514633.1|ensembl:ENSMUSG00000009073(gene)|ensembl:ENSMUST00000109910(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P46662|rcsb pdb:1ISN|rcsb pdb:3WA0|interpro:IPR000798(Ezrin/radixin/moesin ERM)|rcsb pdb:4P7I|rcsb pdb:4ZRK|reactome:R-MMU-2029482|reactome:R-MMU-5627123|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|refseq:NP_001239179.1|refseq:NP_001239180.1|refseq:XP_011241971.1|refseq:NP_001239181.1|refseq:NP_001239182.1 refseq:NP_766295.2|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62141|reactome:R-MMU-2565942|reactome:R-MMU-5625740|reactome:R-MMU-5627123|reactome:R-MMU-5673000|ensembl:ENSMUSG00000014956(gene)|ensembl:ENSMUST00000015100(transcript)|ensembl:ENSMUST00000201360(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process) go:"GO:0042127"(regulation of cell population proliferation) - - figure legend:2 A|comment:The PP1 delta catalytic subunit referred to by the authors is also called the beta catalytic subunit.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2006/08/25 2014/10/16 rogid:xDzmqR+fx4dbxWKxBm5h+sWkzEw10090 rogid:VtNJVyimeiEuRDDWtGswTqoSOH810090 intact-crc:C60F6090AE98D7B0|rigid:I7ZIVHFaBXaNzNdCHky1CNTVgQM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P46662 uniprotkb:Q9DBR7 intact:EBI-644586|uniprotkb:Q8BR03|ensembl:ENSMUSP00000105536 intact:EBI-1014335|uniprotkb:Q8CBV2|uniprotkb:Q99NB6|uniprotkb:Q05A74|ensembl:ENSMUSP00000151842 psi-mi:merl_mouse(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Nf2(gene name)|psi-mi:Nf2(display_short)|uniprotkb:Nf-2(gene name synonym) psi-mi:mypt1_mouse(display_long)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Ppp1r12a(gene name)|psi-mi:Ppp1r12a(display_short)|uniprotkb:Mypt1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jin et al. (2006) imex:IM-14409|pubmed:16885985 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1014356|imex:IM-14409-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035028.2|refseq:XP_006514633.1|ensembl:ENSMUSG00000009073(gene)|ensembl:ENSMUST00000109910(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P46662|rcsb pdb:1ISN|rcsb pdb:3WA0|interpro:IPR000798(Ezrin/radixin/moesin ERM)|rcsb pdb:4P7I|rcsb pdb:4ZRK|reactome:R-MMU-2029482|reactome:R-MMU-5627123|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|refseq:NP_001239179.1|refseq:NP_001239180.1|refseq:XP_011241971.1|refseq:NP_001239181.1|refseq:NP_001239182.1 refseq:NP_082168.1|reactome:R-MMU-2565942|reactome:R-MMU-5625740|reactome:R-MMU-5627123|ensembl:ENSMUSG00000019907(gene)|ensembl:ENSMUST00000219263(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|mint:Q9DBR7|refseq:XP_006513389.1|dip:DIP-29982N go:"GO:0042127"(regulation of cell population proliferation) - - figure legend:2 A|comment:The PP1 delta catalytic subunit referred to by the authors is also called the beta catalytic subunit.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2006/08/25 2014/10/16 rogid:xDzmqR+fx4dbxWKxBm5h+sWkzEw10090 rogid:EI7A6KJizAxFfN09Tm2wKzIyJ7g10090 intact-crc:C60F6090AE98D7B0|rigid:I7ZIVHFaBXaNzNdCHky1CNTVgQM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q10728 uniprotkb:P35240 intact:EBI-918263|uniprotkb:Q62937|uniprotkb:Q9WU33 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 psi-mi:mypt1_rat(display_long)|uniprotkb:Ppp1r12a(gene name)|psi-mi:Ppp1r12a(display_short)|uniprotkb:Mbs(gene name synonym)|uniprotkb:Mypt1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym)|uniprotkb:MBSP(gene name synonym)|uniprotkb:Serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110(gene name synonym)|uniprotkb:Protein phosphatase subunit 1M(gene name synonym) psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jin et al. (2006) imex:IM-14409|pubmed:16885985 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1014548|imex:IM-14409-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620013|refseq:NP_446342.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031775|refseq:XP_006241377.1|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR036770|reactome:R-RNO-2565942|reactome:R-RNO-5625740|reactome:R-RNO-5627123|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex) refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N go:"GO:0042127"(regulation of cell population proliferation) - - figure legend:S1|delivery method:Transfection|expression level:These RTtet-C-merlin cells were engineered to have Dox-inducible merlin expression.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rt4_d6p2t)|taxid:10116(Rattus norvegicus Schwann cell, immature) - 2006/08/25 2014/10/16 rogid:C2cW3Wgc4JZQGtDsP1NgRkzEr1s10116 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 intact-crc:4E8814AA4F5776E2|rigid:/8NGAI7JnABouIG7sce2ql9Qfls false - flag tag:?-?|sufficient binding region:342-595 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)