#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P45844-4 uniprotkb:P45844-4 intact:EBI-8584087|ensembl:ENSP00000381467|intact:MINT-2840281 intact:EBI-8584087|ensembl:ENSP00000381467|intact:MINT-2840281 psi-mi:p45844-4(display_long)|uniprotkb:ABCG1(gene name)|psi-mi:ABCG1(display_short)|uniprotkb:ABC8(gene name synonym)|uniprotkb:ATP-binding cassette transporter 8(gene name synonym)|uniprotkb:WHT1(gene name synonym)|uniprotkb:White protein homolog(gene name synonym)|uniprotkb:G(isoform synonym) psi-mi:p45844-4(display_long)|uniprotkb:ABCG1(gene name)|psi-mi:ABCG1(display_short)|uniprotkb:ABC8(gene name synonym)|uniprotkb:ATP-binding cassette transporter 8(gene name synonym)|uniprotkb:WHT1(gene name synonym)|uniprotkb:White protein homolog(gene name synonym)|uniprotkb:G(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584080|mint:MINT-2840302|imex:IM-10908-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160179(gene)|ensembl:ENST00000398449(transcript)|intact:EBI-8745046(isoform-parent)|uniprotkb:P45844-4(isoform-parent)|mint:MINT-2840304(identity) ensembl:ENSG00000160179(gene)|ensembl:ENST00000398449(transcript)|intact:EBI-8745046(isoform-parent)|uniprotkb:P45844-4(isoform-parent)|mint:MINT-2840303(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F7A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:zgK4c41ah0vF7rs3MlqF9YSkjRw9606 rogid:zgK4c41ah0vF7rs3MlqF9YSkjRw9606 intact-crc:DA552FE1F2CE0654|rigid:wcC96nfGR1CVB1qyXB85zjtgnAw false ha tag:?-?(MINT-2840314) green fluorescent protein tag:?-?(MINT-2840306) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45844-4 uniprotkb:Q9H172 intact:EBI-8584087|ensembl:ENSP00000381467|intact:MINT-2840281 intact:EBI-8584118|ensembl:ENSP00000479253|ensembl:ENSP00000481728|ensembl:ENSP00000484289|uniprotkb:A8K1B5|intact:MINT-2840344|uniprotkb:Q8WWH0|uniprotkb:Q8WWH1|uniprotkb:Q8WWH2 psi-mi:p45844-4(display_long)|uniprotkb:ABCG1(gene name)|psi-mi:ABCG1(display_short)|uniprotkb:ABC8(gene name synonym)|uniprotkb:ATP-binding cassette transporter 8(gene name synonym)|uniprotkb:WHT1(gene name synonym)|uniprotkb:White protein homolog(gene name synonym)|uniprotkb:G(isoform synonym) psi-mi:abcg4_human(display_long)|uniprotkb:ABCG4(gene name)|psi-mi:ABCG4(display_short)|uniprotkb:WHITE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584111|mint:MINT-2840325|imex:IM-10908-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160179(gene)|ensembl:ENST00000398449(transcript)|intact:EBI-8745046(isoform-parent)|uniprotkb:P45844-4(isoform-parent)|mint:MINT-2840334(identity) mint:Q9H172|reactome:R-HSA-1369062|interpro:IPR043926|ensembl:ENST00000615496(transcript)|ensembl:ENST00000619701(transcript)|ensembl:ENST00000622721(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034041"(ABC-type sterol transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|ensembl:ENSG00000172350(gene)|refseq:XP_011541254.1|refseq:NP_071452.2|refseq:NP_001135977.1|refseq:NP_001335120.1|refseq:NP_001335121.1|mint:MINT-2840326(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:May be involved in macrophage lipid homeostasis|comment:"Stoichiometry: 1.0" figure legend:F7A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:zgK4c41ah0vF7rs3MlqF9YSkjRw9606 rogid:HSCN2Fw45BkkxySzxnvQJXQdtJM9606 intact-crc:7262CA2BD3382FC2|rigid:vCB87oT35b2xTSs/WeRoVB50fCg false green fluorescent protein tag:?-?(MINT-2840340) ha tag:?-?(MINT-2840332) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45844-4 uniprotkb:Q9H172 intact:EBI-8584087|ensembl:ENSP00000381467|intact:MINT-2840281 intact:EBI-8584118|ensembl:ENSP00000479253|ensembl:ENSP00000481728|ensembl:ENSP00000484289|uniprotkb:A8K1B5|intact:MINT-2840344|uniprotkb:Q8WWH0|uniprotkb:Q8WWH1|uniprotkb:Q8WWH2 psi-mi:p45844-4(display_long)|uniprotkb:ABCG1(gene name)|psi-mi:ABCG1(display_short)|uniprotkb:ABC8(gene name synonym)|uniprotkb:ATP-binding cassette transporter 8(gene name synonym)|uniprotkb:WHT1(gene name synonym)|uniprotkb:White protein homolog(gene name synonym)|uniprotkb:G(isoform synonym) psi-mi:abcg4_human(display_long)|uniprotkb:ABCG4(gene name)|psi-mi:ABCG4(display_short)|uniprotkb:WHITE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584178|mint:MINT-2840363|imex:IM-10908-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160179(gene)|ensembl:ENST00000398449(transcript)|intact:EBI-8745046(isoform-parent)|uniprotkb:P45844-4(isoform-parent)|mint:MINT-2840372(identity) mint:Q9H172|reactome:R-HSA-1369062|interpro:IPR043926|ensembl:ENST00000615496(transcript)|ensembl:ENST00000619701(transcript)|ensembl:ENST00000622721(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034041"(ABC-type sterol transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|ensembl:ENSG00000172350(gene)|refseq:XP_011541254.1|refseq:NP_071452.2|refseq:NP_001135977.1|refseq:NP_001335120.1|refseq:NP_001335121.1|mint:MINT-2840364(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:May be involved in macrophage lipid homeostasis|comment:"Stoichiometry: 1.0" figure legend:F7C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:zgK4c41ah0vF7rs3MlqF9YSkjRw9606 rogid:HSCN2Fw45BkkxySzxnvQJXQdtJM9606 intact-crc:456C0B2040D30720|rigid:vCB87oT35b2xTSs/WeRoVB50fCg false ha tag:?-?(MINT-2840373) green fluorescent protein tag:?-?(MINT-2840367) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UNQ0 uniprotkb:Q9UNQ0 intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246 intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246 psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym) psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584254|mint:MINT-2840405|imex:IM-10908-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937|mint:MINT-2840406(identity) refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937|mint:MINT-2840414(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606 rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606 intact-crc:9F50E706EA982914|rigid:AeLTmfXH0R0J8WnU8WiXGicTnVI false ha tag:?-?(MINT-2840412) green fluorescent protein tag:?-?(MINT-2840418) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H172 uniprotkb:Q9H172 intact:EBI-8584118|ensembl:ENSP00000479253|ensembl:ENSP00000481728|ensembl:ENSP00000484289|uniprotkb:A8K1B5|intact:MINT-2840344|uniprotkb:Q8WWH0|uniprotkb:Q8WWH1|uniprotkb:Q8WWH2 intact:EBI-8584118|ensembl:ENSP00000479253|ensembl:ENSP00000481728|ensembl:ENSP00000484289|uniprotkb:A8K1B5|intact:MINT-2840344|uniprotkb:Q8WWH0|uniprotkb:Q8WWH1|uniprotkb:Q8WWH2 psi-mi:abcg4_human(display_long)|uniprotkb:ABCG4(gene name)|psi-mi:ABCG4(display_short)|uniprotkb:WHITE2(gene name synonym) psi-mi:abcg4_human(display_long)|uniprotkb:ABCG4(gene name)|psi-mi:ABCG4(display_short)|uniprotkb:WHITE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584216|mint:MINT-2840386|imex:IM-10908-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9H172|reactome:R-HSA-1369062|interpro:IPR043926|ensembl:ENST00000615496(transcript)|ensembl:ENST00000619701(transcript)|ensembl:ENST00000622721(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034041"(ABC-type sterol transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|ensembl:ENSG00000172350(gene)|refseq:XP_011541254.1|refseq:NP_071452.2|refseq:NP_001135977.1|refseq:NP_001335120.1|refseq:NP_001335121.1|mint:MINT-2840387(identity) mint:Q9H172|reactome:R-HSA-1369062|interpro:IPR043926|ensembl:ENST00000615496(transcript)|ensembl:ENST00000619701(transcript)|ensembl:ENST00000622721(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034041"(ABC-type sterol transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|ensembl:ENSG00000172350(gene)|refseq:XP_011541254.1|refseq:NP_071452.2|refseq:NP_001135977.1|refseq:NP_001335120.1|refseq:NP_001335121.1|mint:MINT-2840395(identity) - comment:mint|function:May be involved in macrophage lipid homeostasis|comment:"Stoichiometry: 1.0" comment:mint|function:May be involved in macrophage lipid homeostasis|comment:"Stoichiometry: 1.0" figure legend:F7C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:HSCN2Fw45BkkxySzxnvQJXQdtJM9606 rogid:HSCN2Fw45BkkxySzxnvQJXQdtJM9606 intact-crc:E327CAA5C2DE114D|rigid:/rw7DzY6i33ORsf+bUubAZfKPm0 false ha tag:?-?(MINT-2840390) green fluorescent protein tag:?-?(MINT-2840398) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H221 uniprotkb:Q9H222 intact:EBI-3908684|ensembl:ENSP00000272286|uniprotkb:Q53QN8 intact:EBI-1761423|ensembl:ENSP00000384513|uniprotkb:Q2T9G2|intact:EBI-7969206|intact:MINT-7970776|uniprotkb:Q96QZ2|uniprotkb:Q96QZ3 psi-mi:abcg8_human(display_long)|uniprotkb:ABCG8(gene name)|psi-mi:ABCG8(display_short)|uniprotkb:Sterolin-2(gene name synonym) psi-mi:abcg5_human(display_long)|uniprotkb:ABCG5(gene name)|psi-mi:ABCG5(display_short)|uniprotkb:Sterolin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584316|mint:MINT-2840517|imex:IM-10908-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143921(gene)|ensembl:ENST00000272286(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007588"(excretion)|go:"GO:0010949"(negative regulation of intestinal phytosterol absorption)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038183"(bile acid signaling pathway)|refseq:NP_071882.1|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043235"(receptor complex)|go:"GO:0045796"(negative regulation of intestinal cholesterol absorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|mint:Q9H221|rcsb pdb:5DO7|rcsb pdb:7JR7|reactome:R-HSA-1369062|reactome:R-HSA-5679090|reactome:R-HSA-5679096|reactome:R-HSA-9029569|go:"GO:0042493"|refseq:XP_005264540.1|dip:DIP-42631N|mint:MINT-2840526(identity) refseq:NP_071881.1|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043235"(receptor complex)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|ensembl:ENSG00000138075(gene)|ensembl:ENST00000405322(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007588"(excretion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010949"(negative regulation of intestinal phytosterol absorption)|go:"GO:0045796"(negative regulation of intestinal cholesterol absorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926|mint:Q9H222|rcsb pdb:5DO7|rcsb pdb:7JR7|reactome:R-HSA-1369062|reactome:R-HSA-5679090|reactome:R-HSA-5679096|reactome:R-HSA-9029569|dip:DIP-42630N|mint:MINT-2840518(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:yRouB6khFnEk2cYfy7wqGGnGQtw9606 rogid:NnPK9N0FL+FFY+JL4Zi3yXoDMS89606 intact-crc:D21BBD91621AC7A5|rigid:d7l/WmtLjVI9YjAwpR2ce3cUCp8 false ha tag:?-?(MINT-2840527) green fluorescent protein tag:?-?(MINT-2840521) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45844-4 uniprotkb:Q9H222 intact:EBI-8584087|ensembl:ENSP00000381467|intact:MINT-2840281 intact:EBI-1761423|ensembl:ENSP00000384513|uniprotkb:Q2T9G2|intact:EBI-7969206|intact:MINT-7970776|uniprotkb:Q96QZ2|uniprotkb:Q96QZ3 psi-mi:p45844-4(display_long)|uniprotkb:ABCG1(gene name)|psi-mi:ABCG1(display_short)|uniprotkb:ABC8(gene name synonym)|uniprotkb:ATP-binding cassette transporter 8(gene name synonym)|uniprotkb:WHT1(gene name synonym)|uniprotkb:White protein homolog(gene name synonym)|uniprotkb:G(isoform synonym) psi-mi:abcg5_human(display_long)|uniprotkb:ABCG5(gene name)|psi-mi:ABCG5(display_short)|uniprotkb:Sterolin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584286|mint:MINT-2840480|imex:IM-10908-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160179(gene)|ensembl:ENST00000398449(transcript)|intact:EBI-8745046(isoform-parent)|uniprotkb:P45844-4(isoform-parent)|mint:MINT-2840481(identity) refseq:NP_071881.1|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043235"(receptor complex)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|ensembl:ENSG00000138075(gene)|ensembl:ENST00000405322(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007588"(excretion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010949"(negative regulation of intestinal phytosterol absorption)|go:"GO:0045796"(negative regulation of intestinal cholesterol absorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926|mint:Q9H222|rcsb pdb:5DO7|rcsb pdb:7JR7|reactome:R-HSA-1369062|reactome:R-HSA-5679090|reactome:R-HSA-5679096|reactome:R-HSA-9029569|dip:DIP-42630N|mint:MINT-2840489(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:zgK4c41ah0vF7rs3MlqF9YSkjRw9606 rogid:NnPK9N0FL+FFY+JL4Zi3yXoDMS89606 intact-crc:00FB143ADAC014FA|rigid:JR74UoiNrBA87uNTDTL4JKh0Nro false ha tag:?-?(MINT-2840487) green fluorescent protein tag:?-?(MINT-2840495) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H221 uniprotkb:Q9H222 intact:EBI-3908684|ensembl:ENSP00000272286|uniprotkb:Q53QN8 intact:EBI-1761423|ensembl:ENSP00000384513|uniprotkb:Q2T9G2|intact:EBI-7969206|intact:MINT-7970776|uniprotkb:Q96QZ2|uniprotkb:Q96QZ3 psi-mi:abcg8_human(display_long)|uniprotkb:ABCG8(gene name)|psi-mi:ABCG8(display_short)|uniprotkb:Sterolin-2(gene name synonym) psi-mi:abcg5_human(display_long)|uniprotkb:ABCG5(gene name)|psi-mi:ABCG5(display_short)|uniprotkb:Sterolin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Engel et al. (2006) pubmed:16870176|imex:IM-10908|mint:MINT-5218866 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8584420|mint:MINT-2840569|imex:IM-10908-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000143921(gene)|ensembl:ENST00000272286(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007588"(excretion)|go:"GO:0010949"(negative regulation of intestinal phytosterol absorption)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038183"(bile acid signaling pathway)|refseq:NP_071882.1|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043235"(receptor complex)|go:"GO:0045796"(negative regulation of intestinal cholesterol absorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR043926|mint:Q9H221|rcsb pdb:5DO7|rcsb pdb:7JR7|reactome:R-HSA-1369062|reactome:R-HSA-5679090|reactome:R-HSA-5679096|reactome:R-HSA-9029569|go:"GO:0042493"|refseq:XP_005264540.1|dip:DIP-42631N|mint:MINT-2840570(identity) refseq:NP_071881.1|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0043235"(receptor complex)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042632"(cholesterol homeostasis)|ensembl:ENSG00000138075(gene)|ensembl:ENST00000405322(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007588"(excretion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010949"(negative regulation of intestinal phytosterol absorption)|go:"GO:0045796"(negative regulation of intestinal cholesterol absorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926|mint:Q9H222|rcsb pdb:5DO7|rcsb pdb:7JR7|reactome:R-HSA-1369062|reactome:R-HSA-5679090|reactome:R-HSA-5679096|reactome:R-HSA-9029569|dip:DIP-42630N|mint:MINT-2840578(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/02 2014/10/16 rogid:yRouB6khFnEk2cYfy7wqGGnGQtw9606 rogid:NnPK9N0FL+FFY+JL4Zi3yXoDMS89606 intact-crc:85D8A67C0D63640D|rigid:d7l/WmtLjVI9YjAwpR2ce3cUCp8 false green fluorescent protein tag:?-?(MINT-2840576) ha tag:?-?(MINT-2840582) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)