#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61149	uniprotkb:Q63237	intact:EBI-8523428|intact:MINT-2635533|uniprotkb:P10935|ensembl:ENSRNOP00000018577|ensembl:ENSRNOP00000070685	intact:EBI-8523405|intact:MINT-2635520	psi-mi:fgf1_rat(display_long)|uniprotkb:Fgf1(gene name)|psi-mi:Fgf1(display_short)|uniprotkb:Fgf-1(gene name synonym)|uniprotkb:Fgfa(gene name synonym)|uniprotkb:Heparin-binding growth factor 1(gene name synonym)|uniprotkb:Acidic fibroblast growth factor(gene name synonym)	psi-mi:q63237_rat(display_long)|uniprotkb:Fgfr2(gene name)|psi-mi:Fgfr2(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Christensen et al. (2006)	mint:MINT-5218655|pubmed:16709412|imex:IM-10853	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8523397|mint:MINT-2635548|imex:IM-10853-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2605|refseq:NP_036978.1|refseq:XP_006254712.1|refseq:XP_006254713.1|refseq:XP_006254714.1|ensembl:ENSRNOG00000013867(gene)|ensembl:ENSRNOT00000018577(transcript)|ensembl:ENSRNOT00000087408(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060681"(branch elongation involved in ureteric bud branching)|go:"GO:0072163"(mesonephric epithelium development)|go:"GO:1901509"(regulation of endothelial tube morphogenesis)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000544"(regulation of endothelial cell chemotaxis to fibroblast growth factor)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028210|mint:P61149|rcsb pdb:2J3P|rcsb pdb:2UUS|reactome:R-RNO-109704|reactome:R-RNO-1257604|reactome:R-RNO-190322|reactome:R-RNO-190370|reactome:R-RNO-190371|reactome:R-RNO-190372|reactome:R-RNO-190373|reactome:R-RNO-190375|reactome:R-RNO-190377|reactome:R-RNO-5654219|reactome:R-RNO-5654221|reactome:R-RNO-5654227|reactome:R-RNO-5654228|reactome:R-RNO-5654687|reactome:R-RNO-5654688|reactome:R-RNO-5654689|reactome:R-RNO-5654693|reactome:R-RNO-5654695|reactome:R-RNO-5654699|reactome:R-RNO-5654700|reactome:R-RNO-5654704|reactome:R-RNO-5654706|reactome:R-RNO-5654710|reactome:R-RNO-5654712|reactome:R-RNO-5654719|reactome:R-RNO-5654720|reactome:R-RNO-5654726|reactome:R-RNO-5654727|reactome:R-RNO-5654732|reactome:R-RNO-5654733|reactome:R-RNO-5673001|reactome:R-RNO-6811558|mint:MINT-2635550(identity)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001103362.1|rgd:2611|mint:Q63237|interpro:IPR036179|interpro:IPR041159|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003416"(endochondral bone growth)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035602"(fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell)|go:"GO:0035603"(fibroblast growth factor receptor signaling pathway involved in hemopoiesis)|go:"GO:0035604"(fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048565"(digestive tract development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060174"(limb bud formation)|go:"GO:0060348"(bone development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060365"(coronal suture morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060512"(prostate gland morphogenesis)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0060595"(fibroblast growth factor receptor signaling pathway involved in mammary gland specification)|go:"GO:0060601"(lateral sprouting from an epithelium)|go:"GO:0060615"(mammary gland bud formation)|go:"GO:0060664"(epithelial cell proliferation involved in salivary gland morphogenesis)|go:"GO:0060667"(branch elongation involved in salivary gland morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060688"(regulation of morphogenesis of a branching structure)|go:"GO:0060915"(mesenchymal cell differentiation involved in lung development)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|mint:MINT-2635549(identity)	-	comment:mint|function:The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors|comment:"Stoichiometry: 1.0"	comment:"fragmentation type: fragment"|comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F1|kinetics:kd 5 nanomolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/06/22	2014/10/16	rogid:ZOV+Utsn9XSOaEQ1WLoUCVZUpZ410116	rogid:Xxecc3//Cjk0skFBnEY6WStfnrU10116	intact-crc:7D29FAD957E89752|rigid:Wdlsk57FvLxrXLZqVt79664PDM0	false	-	binding-associated region:166-384(MINT-2635573)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61149	uniprotkb:P16092	intact:EBI-8523428|intact:MINT-2635533|uniprotkb:P10935|ensembl:ENSRNOP00000018577|ensembl:ENSRNOP00000070685	intact:EBI-7953898|uniprotkb:Q60830|uniprotkb:Q01736|uniprotkb:Q8CFK8|intact:MINT-2635590|uniprotkb:Q80T10|uniprotkb:E9Q2P4|uniprotkb:Q61562|uniprotkb:Q9QZM7|ensembl:ENSMUSP00000081041	psi-mi:fgf1_rat(display_long)|uniprotkb:Fgf1(gene name)|psi-mi:Fgf1(display_short)|uniprotkb:Fgf-1(gene name synonym)|uniprotkb:Fgfa(gene name synonym)|uniprotkb:Heparin-binding growth factor 1(gene name synonym)|uniprotkb:Acidic fibroblast growth factor(gene name synonym)	psi-mi:fgfr1_mouse(display_long)|uniprotkb:Fgfr1(gene name)|psi-mi:Fgfr1(display_short)|uniprotkb:Flg(gene name synonym)|uniprotkb:Basic fibroblast growth factor receptor 1(gene name synonym)|uniprotkb:MFR(gene name synonym)|uniprotkb:Proto-oncogene c-Fgr(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Christensen et al. (2006)	mint:MINT-5218655|pubmed:16709412|imex:IM-10853	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8523484|mint:MINT-2635576|imex:IM-10853-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2605|refseq:NP_036978.1|refseq:XP_006254712.1|refseq:XP_006254713.1|refseq:XP_006254714.1|ensembl:ENSRNOG00000013867(gene)|ensembl:ENSRNOT00000018577(transcript)|ensembl:ENSRNOT00000087408(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060681"(branch elongation involved in ureteric bud branching)|go:"GO:0072163"(mesonephric epithelium development)|go:"GO:1901509"(regulation of endothelial tube morphogenesis)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000544"(regulation of endothelial cell chemotaxis to fibroblast growth factor)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028210|mint:P61149|rcsb pdb:2J3P|rcsb pdb:2UUS|reactome:R-RNO-109704|reactome:R-RNO-1257604|reactome:R-RNO-190322|reactome:R-RNO-190370|reactome:R-RNO-190371|reactome:R-RNO-190372|reactome:R-RNO-190373|reactome:R-RNO-190375|reactome:R-RNO-190377|reactome:R-RNO-5654219|reactome:R-RNO-5654221|reactome:R-RNO-5654227|reactome:R-RNO-5654228|reactome:R-RNO-5654687|reactome:R-RNO-5654688|reactome:R-RNO-5654689|reactome:R-RNO-5654693|reactome:R-RNO-5654695|reactome:R-RNO-5654699|reactome:R-RNO-5654700|reactome:R-RNO-5654704|reactome:R-RNO-5654706|reactome:R-RNO-5654710|reactome:R-RNO-5654712|reactome:R-RNO-5654719|reactome:R-RNO-5654720|reactome:R-RNO-5654726|reactome:R-RNO-5654727|reactome:R-RNO-5654732|reactome:R-RNO-5654733|reactome:R-RNO-5673001|reactome:R-RNO-6811558|mint:MINT-2635584(identity)	refseq:XP_011240423.1|refseq:NP_034336.2|refseq:NP_001073378.1|refseq:NP_001073377.1|refseq:XP_006509073.1|refseq:XP_006509075.1|dip:DIP-6033N|ensembl:ENSMUSG00000031565(gene)|ensembl:ENSMUST00000084027(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001759"(organ induction)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021837"(motogenic signaling involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043583"(ear development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028174|interpro:IPR036179|interpro:IPR041159|mint:P16092|rcsb pdb:2CKN|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190370|reactome:R-MMU-190373|reactome:R-MMU-190374|reactome:R-MMU-445144|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048378"(regulation of lateral mesodermal cell fate specification)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051174"(regulation of phosphorus metabolic process)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070640"(vitamin D3 metabolic process)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|go:"GO:0090272"(negative regulation of fibroblast growth factor production)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000830"(positive regulation of parathyroid hormone secretion)|go:"GO:2001239"(regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)|mint:MINT-2635577(identity)	-	comment:mint|function:The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors|comment:"Stoichiometry: 1.0"	comment:mint|function:"Receptor for basic fibroblast growth factor. A shorter form of the receptor could be a receptor for FGF1 (aFGF)"|comment:homomint|comment:"Stoichiometry: 1.0"	figure legend:F1|kinetics:kd 5 nanomolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/06/22	2014/10/16	rogid:ZOV+Utsn9XSOaEQ1WLoUCVZUpZ410116	rogid:JSLRQxD7C6jJyldtTkRE1Zn+AvE10090	intact-crc:7C1708A07F24C4A9|rigid:0N4w99BaNjv848oBAIVvcvqT83s	false	-	binding-associated region:141-365(MINT-2635578)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P16092	uniprotkb:P13596	intact:EBI-7953898|uniprotkb:Q60830|uniprotkb:Q01736|uniprotkb:Q8CFK8|intact:MINT-2635590|uniprotkb:Q80T10|uniprotkb:E9Q2P4|uniprotkb:Q61562|uniprotkb:Q9QZM7|ensembl:ENSMUSP00000081041	intact:EBI-916499	psi-mi:fgfr1_mouse(display_long)|uniprotkb:Fgfr1(gene name)|psi-mi:Fgfr1(display_short)|uniprotkb:Flg(gene name synonym)|uniprotkb:Basic fibroblast growth factor receptor 1(gene name synonym)|uniprotkb:MFR(gene name synonym)|uniprotkb:Proto-oncogene c-Fgr(gene name synonym)	psi-mi:ncam1_rat(display_long)|uniprotkb:Ncam1(gene name)|psi-mi:Ncam1(display_short)|uniprotkb:Ncam(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Christensen et al. (2006)	mint:MINT-5218655|pubmed:16709412|imex:IM-10853	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8523526|mint:MINT-2635683|imex:IM-10853-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011240423.1|refseq:NP_034336.2|refseq:NP_001073378.1|refseq:NP_001073377.1|refseq:XP_006509073.1|refseq:XP_006509075.1|dip:DIP-6033N|ensembl:ENSMUSG00000031565(gene)|ensembl:ENSMUST00000084027(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001759"(organ induction)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021837"(motogenic signaling involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043583"(ear development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028174|interpro:IPR036179|interpro:IPR041159|mint:P16092|rcsb pdb:2CKN|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190370|reactome:R-MMU-190373|reactome:R-MMU-190374|reactome:R-MMU-445144|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048378"(regulation of lateral mesodermal cell fate specification)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051174"(regulation of phosphorus metabolic process)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070640"(vitamin D3 metabolic process)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|go:"GO:0090272"(negative regulation of fibroblast growth factor production)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000830"(positive regulation of parathyroid hormone secretion)|go:"GO:2001239"(regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)|mint:MINT-2635684(identity)	rgd:67378|interpro:IPR003599(Immunoglobulin subtype)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014823"(response to activity)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048666"(neuron development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2001260"(regulation of semaphorin-plexin signaling pathway)|rcsb pdb:1EPF|rcsb pdb:1LWR|rcsb pdb:1QZ1|reactome:R-RNO-375165|reactome:R-RNO-419037|reactome:R-RNO-445144|reactome:R-RNO-5673001|refseq:NP_113709.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR009138(Neural cell adhesion)|mint:P13596|interpro:IPR033019|interpro:IPR036116|interpro:IPR036179|mint:MINT-2635691(identity)	-	comment:mint|function:"Receptor for basic fibroblast growth factor. A shorter form of the receptor could be a receptor for FGF1 (aFGF)"|comment:homomint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:T1|figure legend:F2|kinetics:kd 9,97 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/06/22	2014/10/16	rogid:JSLRQxD7C6jJyldtTkRE1Zn+AvE10090	rogid:QM7RSMedN9uQfR5L0S/24RL15WM10116	intact-crc:33120A56B08343EE|rigid:9qXiY9f8aqTK31vphQ3zfjsKV1o	false	binding-associated region:141-365(MINT-2635685)	binding-associated region:507-705(MINT-2635732)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q63237	uniprotkb:P13596	intact:EBI-8523405|intact:MINT-2635520	intact:EBI-916499	psi-mi:q63237_rat(display_long)|uniprotkb:Fgfr2(gene name)|psi-mi:Fgfr2(display_short)	psi-mi:ncam1_rat(display_long)|uniprotkb:Ncam1(gene name)|psi-mi:Ncam1(display_short)|uniprotkb:Ncam(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Christensen et al. (2006)	mint:MINT-5218655|pubmed:16709412|imex:IM-10853	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8523503|mint:MINT-2635638|imex:IM-10853-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001103362.1|rgd:2611|mint:Q63237|interpro:IPR036179|interpro:IPR041159|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003416"(endochondral bone growth)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035602"(fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell)|go:"GO:0035603"(fibroblast growth factor receptor signaling pathway involved in hemopoiesis)|go:"GO:0035604"(fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048565"(digestive tract development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060174"(limb bud formation)|go:"GO:0060348"(bone development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060365"(coronal suture morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060512"(prostate gland morphogenesis)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0060595"(fibroblast growth factor receptor signaling pathway involved in mammary gland specification)|go:"GO:0060601"(lateral sprouting from an epithelium)|go:"GO:0060615"(mammary gland bud formation)|go:"GO:0060664"(epithelial cell proliferation involved in salivary gland morphogenesis)|go:"GO:0060667"(branch elongation involved in salivary gland morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060688"(regulation of morphogenesis of a branching structure)|go:"GO:0060915"(mesenchymal cell differentiation involved in lung development)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|mint:MINT-2635639(identity)	rgd:67378|interpro:IPR003599(Immunoglobulin subtype)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014823"(response to activity)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048666"(neuron development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2001260"(regulation of semaphorin-plexin signaling pathway)|rcsb pdb:1EPF|rcsb pdb:1LWR|rcsb pdb:1QZ1|reactome:R-RNO-375165|reactome:R-RNO-419037|reactome:R-RNO-445144|reactome:R-RNO-5673001|refseq:NP_113709.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR009138(Neural cell adhesion)|mint:P13596|interpro:IPR033019|interpro:IPR036116|interpro:IPR036179|mint:MINT-2635646(identity)	-	comment:"fragmentation type: fragment"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:T1|figure legend:F2|kinetics:kd 9,21 micromolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/06/22	2014/10/16	rogid:Xxecc3//Cjk0skFBnEY6WStfnrU10116	rogid:QM7RSMedN9uQfR5L0S/24RL15WM10116	intact-crc:7D55086063C7DD90|rigid:SNNecsbUMHvBtA0C9svplrOp1KI	false	binding-associated region:166-384(MINT-2635640)	binding-associated region:507-705(MINT-2635697)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P16092	uniprotkb:P13596	intact:EBI-7953898|uniprotkb:Q60830|uniprotkb:Q01736|uniprotkb:Q8CFK8|intact:MINT-2635590|uniprotkb:Q80T10|uniprotkb:E9Q2P4|uniprotkb:Q61562|uniprotkb:Q9QZM7|ensembl:ENSMUSP00000081041	intact:EBI-916499	psi-mi:fgfr1_mouse(display_long)|uniprotkb:Fgfr1(gene name)|psi-mi:Fgfr1(display_short)|uniprotkb:Flg(gene name synonym)|uniprotkb:Basic fibroblast growth factor receptor 1(gene name synonym)|uniprotkb:MFR(gene name synonym)|uniprotkb:Proto-oncogene c-Fgr(gene name synonym)	psi-mi:ncam1_rat(display_long)|uniprotkb:Ncam1(gene name)|psi-mi:Ncam1(display_short)|uniprotkb:Ncam(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Christensen et al. (2006)	mint:MINT-5218655|pubmed:16709412|imex:IM-10853	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8523573|mint:MINT-2635740|imex:IM-10853-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011240423.1|refseq:NP_034336.2|refseq:NP_001073378.1|refseq:NP_001073377.1|refseq:XP_006509073.1|refseq:XP_006509075.1|dip:DIP-6033N|ensembl:ENSMUSG00000031565(gene)|ensembl:ENSMUST00000084027(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001759"(organ induction)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021837"(motogenic signaling involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043583"(ear development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028174|interpro:IPR036179|interpro:IPR041159|mint:P16092|rcsb pdb:2CKN|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190370|reactome:R-MMU-190373|reactome:R-MMU-190374|reactome:R-MMU-445144|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048378"(regulation of lateral mesodermal cell fate specification)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051174"(regulation of phosphorus metabolic process)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070640"(vitamin D3 metabolic process)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|go:"GO:0090272"(negative regulation of fibroblast growth factor production)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000830"(positive regulation of parathyroid hormone secretion)|go:"GO:2001239"(regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)|mint:MINT-2635748(identity)	rgd:67378|interpro:IPR003599(Immunoglobulin subtype)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014823"(response to activity)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048666"(neuron development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2001260"(regulation of semaphorin-plexin signaling pathway)|rcsb pdb:1EPF|rcsb pdb:1LWR|rcsb pdb:1QZ1|reactome:R-RNO-375165|reactome:R-RNO-419037|reactome:R-RNO-445144|reactome:R-RNO-5673001|refseq:NP_113709.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR009138(Neural cell adhesion)|mint:P13596|interpro:IPR033019|interpro:IPR036116|interpro:IPR036179|mint:MINT-2635741(identity)	-	comment:mint|function:"Receptor for basic fibroblast growth factor. A shorter form of the receptor could be a receptor for FGF1 (aFGF)"|comment:homomint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:T1|figure legend:F2|kinetics:kd 2,58 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/06/22	2014/10/16	rogid:JSLRQxD7C6jJyldtTkRE1Zn+AvE10090	rogid:QM7RSMedN9uQfR5L0S/24RL15WM10116	intact-crc:AFF38DD6011CD89E|rigid:9qXiY9f8aqTK31vphQ3zfjsKV1o	false	binding-associated region:141-365(MINT-2635749)	binding-associated region:612-705(MINT-2635742)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q63237	uniprotkb:P13596	intact:EBI-8523405|intact:MINT-2635520	intact:EBI-916499	psi-mi:q63237_rat(display_long)|uniprotkb:Fgfr2(gene name)|psi-mi:Fgfr2(display_short)	psi-mi:ncam1_rat(display_long)|uniprotkb:Ncam1(gene name)|psi-mi:Ncam1(display_short)|uniprotkb:Ncam(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Christensen et al. (2006)	mint:MINT-5218655|pubmed:16709412|imex:IM-10853	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8523550|mint:MINT-2635716|imex:IM-10853-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001103362.1|rgd:2611|mint:Q63237|interpro:IPR036179|interpro:IPR041159|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003416"(endochondral bone growth)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035602"(fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell)|go:"GO:0035603"(fibroblast growth factor receptor signaling pathway involved in hemopoiesis)|go:"GO:0035604"(fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045471"(response to ethanol)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048565"(digestive tract development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060174"(limb bud formation)|go:"GO:0060348"(bone development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060365"(coronal suture morphogenesis)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060512"(prostate gland morphogenesis)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0060595"(fibroblast growth factor receptor signaling pathway involved in mammary gland specification)|go:"GO:0060601"(lateral sprouting from an epithelium)|go:"GO:0060615"(mammary gland bud formation)|go:"GO:0060664"(epithelial cell proliferation involved in salivary gland morphogenesis)|go:"GO:0060667"(branch elongation involved in salivary gland morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060688"(regulation of morphogenesis of a branching structure)|go:"GO:0060915"(mesenchymal cell differentiation involved in lung development)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|mint:MINT-2635724(identity)	rgd:67378|interpro:IPR003599(Immunoglobulin subtype)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014823"(response to activity)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048666"(neuron development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2001260"(regulation of semaphorin-plexin signaling pathway)|rcsb pdb:1EPF|rcsb pdb:1LWR|rcsb pdb:1QZ1|reactome:R-RNO-375165|reactome:R-RNO-419037|reactome:R-RNO-445144|reactome:R-RNO-5673001|refseq:NP_113709.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR009138(Neural cell adhesion)|mint:P13596|interpro:IPR033019|interpro:IPR036116|interpro:IPR036179|mint:MINT-2635717(identity)	-	comment:"fragmentation type: fragment"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:T1|figure legend:F2|kinetics:kd 1,75 micromolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/06/22	2014/10/16	rogid:Xxecc3//Cjk0skFBnEY6WStfnrU10116	rogid:QM7RSMedN9uQfR5L0S/24RL15WM10116	intact-crc:54FFE0AFFD81E644|rigid:SNNecsbUMHvBtA0C9svplrOp1KI	false	binding-associated region:166-384(MINT-2635729)	binding-associated region:612-705(MINT-2635718)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)