#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P77335	uniprotkb:P77335	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:"MI:0030"(cross-linking study)	Eifler et al. (2006)	mint:MINT-5218621|pubmed:16688219|imex:IM-10903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8516605|mint:MINT-2737982|imex:IM-10903-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2737988(identity)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2737983(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:the interaction is an oligomerization|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/03	2014/10/16	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	intact-crc:5ABCDACC581A2B6E|rigid:/XOd3oIdQTBICIjSxzfESF6WkIU	false	-	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P77335	uniprotkb:P77335	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:"MI:0071"(molecular sieving)	Eifler et al. (2006)	mint:MINT-5218621|pubmed:16688219|imex:IM-10903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8516684|mint:MINT-2737960|imex:IM-10903-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2737961(identity)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2737962(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F3A|comment:the interaction is an oligomerization|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/03	2014/10/16	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	intact-crc:6D0951160330EC5B|rigid:/XOd3oIdQTBICIjSxzfESF6WkIU	false	-	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P77335	uniprotkb:P77335	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:"MI:0040"(electron microscopy)	Eifler et al. (2006)	mint:MINT-5218621|pubmed:16688219|imex:IM-10903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8516658|mint:MINT-2738000|imex:IM-10903-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2738001(identity)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2738006(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F4|figure legend:F5|figure legend:F6|comment:the interaction is an oligomerization|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/03	2014/10/16	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	intact-crc:8F682D41CD70110B|rigid:/XOd3oIdQTBICIjSxzfESF6WkIU	false	-	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P77335	uniprotkb:P77335	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name)	psi-mi:"MI:0016"(circular dichroism)	Eifler et al. (2006)	mint:MINT-5218621|pubmed:16688219|imex:IM-10903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8516708|mint:MINT-2738018|imex:IM-10903-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2738024(identity)	refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW|mint:MINT-2738019(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F4|figure legend:F5|figure legend:F6|comment:the interaction is an oligomerization|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/03	2014/10/16	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333	intact-crc:2B4373D62D11E745|rigid:/XOd3oIdQTBICIjSxzfESF6WkIU	false	-	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)