#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q04636 uniprotkb:P22336 intact:EBI-27863|uniprotkb:D6VZA4|ensemblfungi:YML069W intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C psi-mi:pob3_yeast(display_long)|uniprotkb:YML069W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit POB3(gene name synonym)|uniprotkb:POB3(gene name)|psi-mi:POB3(display_short) psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) VanDemark et al. (2006) pubmed:16678108|imex:IM-19284 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-962457|imex:IM-19284-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013642.1|sgd:S000004534|dip:DIP-4083N|mint:Q04636|ensemblfungi:YML069W(gene)|ensemblfungi:YML069W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR038167|rcsb pdb:2GCJ|rcsb pdb:2GCL|rcsb pdb:3F5R|rcsb pdb:4PQ0|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955|go:"GO:0031298"(replication fork protection complex) refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336 - crc64:02C04F620C7B1450 crc64:7EB8DFA6910EF8A8 figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/05 2014/10/16 rogid:P1VkOQ4LPSsxfSZaDykpvS9FRPU559292 rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292 intact-crc:19C414DDB137109B|rigid:S4nmX8TGsefH2CYLN8iLRZes6BQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04636 uniprotkb:P22336 intact:EBI-27863|uniprotkb:D6VZA4|ensemblfungi:YML069W intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C psi-mi:pob3_yeast(display_long)|uniprotkb:YML069W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit POB3(gene name synonym)|uniprotkb:POB3(gene name)|psi-mi:POB3(display_short) psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) VanDemark et al. (2006) pubmed:16678108|imex:IM-19284 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-962461|imex:IM-19284-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013642.1|sgd:S000004534|dip:DIP-4083N|mint:Q04636|ensemblfungi:YML069W(gene)|ensemblfungi:YML069W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR038167|rcsb pdb:2GCJ|rcsb pdb:2GCL|rcsb pdb:3F5R|rcsb pdb:4PQ0|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955|go:"GO:0031298"(replication fork protection complex) refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336 - crc64:02C04F620C7B1450 crc64:7EB8DFA6910EF8A8 figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/05 2014/10/16 rogid:P1VkOQ4LPSsxfSZaDykpvS9FRPU559292 rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292 intact-crc:DB08E7E9DA4D0459|rigid:S4nmX8TGsefH2CYLN8iLRZes6BQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P22336 uniprotkb:Q04636 intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C intact:EBI-27863|uniprotkb:D6VZA4|ensemblfungi:YML069W psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym) psi-mi:pob3_yeast(display_long)|uniprotkb:YML069W(locus name)|uniprotkb:Facilitates chromatin transcription complex subunit POB3(gene name synonym)|uniprotkb:POB3(gene name)|psi-mi:POB3(display_short) psi-mi:"MI:0096"(pull down) VanDemark et al. (2006) pubmed:16678108|imex:IM-19284 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-962471|imex:IM-19284-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336 refseq:NP_013642.1|sgd:S000004534|dip:DIP-4083N|mint:Q04636|ensemblfungi:YML069W(gene)|ensemblfungi:YML069W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR038167|rcsb pdb:2GCJ|rcsb pdb:2GCL|rcsb pdb:3F5R|rcsb pdb:4PQ0|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6804756|reactome:R-SCE-75955|go:"GO:0031298"(replication fork protection complex) - crc64:7EB8DFA6910EF8A8 crc64:02C04F620C7B1450 figure legend:5C|comment:"Histidine-tagged versions of POB3 used to show interaction: POB3 fragment aa237-477, SPT16-POB3 with or without indicated POB3 mutations and SPT16-POB3(phe133ser)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/05 2014/10/16 rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292 rogid:P1VkOQ4LPSsxfSZaDykpvS9FRPU559292 intact-crc:96C9F6FDBE4F078B|rigid:S4nmX8TGsefH2CYLN8iLRZes6BQ false - glutathione s tranferase tag:?-?|binding-associated region:237-477|mutation decreasing interaction:308-308|mutation decreasing interaction:308-308 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)