#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P16387	uniprotkb:P40530	intact:EBI-12475|ensemblfungi:YER178W|uniprotkb:D3DM87	intact:EBI-2610722|uniprotkb:D6VVP0|ensemblfungi:YIL042C	psi-mi:odpa_yeast(display_long)|uniprotkb:YER178W(locus name)|uniprotkb:PDA1(gene name)|psi-mi:PDA1(display_short)|uniprotkb:Pyruvate dehydrogenase complex component E1 alpha(gene name synonym)	psi-mi:pdk1_yeast(display_long)|uniprotkb:PKP1(gene name)|psi-mi:PKP1(display_short)|uniprotkb:Protein kinase of PDH protein 1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex kinase 1(gene name synonym)|uniprotkb:[Pyruvate dehydrogenase [lipoamide]] kinase 1(gene name synonym)|uniprotkb:YIL042C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Krause-Buchholz et al. (2006)	pubmed:16643908|imex:IM-11071|mint:MINT-5218575	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8501554|mint:MINT-2832135|imex:IM-11071-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER178W_mRNA(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|interpro:IPR029061|reactome:R-SCE-389661|reactome:R-SCE-70268|ensemblfungi:YER178W(gene)|refseq:NP_011105.4|sgd:S000000980|mint:P16387|dip:DIP-5117N|mint:MINT-2832136(identity)	refseq:NP_012222.1|sgd:S000001304|ensemblfungi:YIL042C(gene)|ensemblfungi:YIL042C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0015976"(carbon utilization)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:1901524"(regulation of mitophagy)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|dip:DIP-2547N|mint:P40530|mint:MINT-2832141(identity)	-	crc64:37019BD9E84D0002|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F7B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/07/22	2014/10/16	rogid:1RHLkNmON+CMDE10VjHdMnS8PwM559292	rogid:0rYgCCKuMjgpxrhbL6SyvHwnejU559292	intact-crc:CA8A73C60FB70CCD|rigid:Cai/9NhoRr7reznEhyzG9IwztMA	false	calmodulin binding peptide plus protein a tag:?-?(MINT-2832147)	myc tag:?-?(MINT-2832150)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39533	uniprotkb:Q04935	intact:EBI-2109|uniprotkb:D6VVZ3|ensemblfungi:YJL200C	intact:EBI-36910|uniprotkb:D6VSL2|ensemblfungi:YDR231C	psi-mi:acon2_yeast(display_long)|uniprotkb:ACO2(gene name)|psi-mi:ACO2(display_short)|uniprotkb:Aconitase 2(gene name synonym)|uniprotkb:J0327(orf name)|uniprotkb:YJL200C(locus name)	psi-mi:cox20_yeast(display_long)|uniprotkb:COX20(gene name)|psi-mi:COX20(display_short)|uniprotkb:YD9934.15c(orf name)|uniprotkb:YDR231C(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Krause-Buchholz et al. (2006)	pubmed:16643908|imex:IM-11071|mint:MINT-5218575	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8501584|mint:MINT-2836557|imex:IM-11071-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012335.1|sgd:S000003736|dip:DIP-1376N|mint:P39533|ensemblfungi:YJL200C(gene)|ensemblfungi:YJL200C_mRNA(transcript)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:MINT-2836561(identity)	refseq:NP_010517.1|sgd:S000002639|mint:Q04935|dip:DIP-5755N|ensemblfungi:YDR231C(gene)|ensemblfungi:YDR231C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1902884"(positive regulation of response to oxidative stress)|interpro:IPR022533|mint:MINT-2836558(identity)	-	comment:"Stoichiometry: 1.0"	-	figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/07/22	2014/10/16	rogid:lwfD8JbHha1FdR8PrYoI1k103FI559292	rogid:VJUlj5H4Fq9YlWXPBMWFKfSAuqw559292	intact-crc:470BB8C8667DA7BB|rigid:0sbWgykmlWsjmTRnsv05CbrLEFE	false	-	-	1	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39533	uniprotkb:P40530	intact:EBI-2109|uniprotkb:D6VVZ3|ensemblfungi:YJL200C	intact:EBI-2610722|uniprotkb:D6VVP0|ensemblfungi:YIL042C	psi-mi:acon2_yeast(display_long)|uniprotkb:ACO2(gene name)|psi-mi:ACO2(display_short)|uniprotkb:Aconitase 2(gene name synonym)|uniprotkb:J0327(orf name)|uniprotkb:YJL200C(locus name)	psi-mi:pdk1_yeast(display_long)|uniprotkb:PKP1(gene name)|psi-mi:PKP1(display_short)|uniprotkb:Protein kinase of PDH protein 1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex kinase 1(gene name synonym)|uniprotkb:[Pyruvate dehydrogenase [lipoamide]] kinase 1(gene name synonym)|uniprotkb:YIL042C(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Krause-Buchholz et al. (2006)	pubmed:16643908|imex:IM-11071|mint:MINT-5218575	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8501584|mint:MINT-2836557|imex:IM-11071-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012335.1|sgd:S000003736|dip:DIP-1376N|mint:P39533|ensemblfungi:YJL200C(gene)|ensemblfungi:YJL200C_mRNA(transcript)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:MINT-2836561(identity)	refseq:NP_012222.1|sgd:S000001304|ensemblfungi:YIL042C(gene)|ensemblfungi:YIL042C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0015976"(carbon utilization)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034622"|go:"GO:1901524"(regulation of mitophagy)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|dip:DIP-2547N|mint:P40530|mint:MINT-2836559(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/07/22	2014/10/16	rogid:lwfD8JbHha1FdR8PrYoI1k103FI559292	rogid:0rYgCCKuMjgpxrhbL6SyvHwnejU559292	intact-crc:470BB8C8667DA7BB|rigid:0sbWgykmlWsjmTRnsv05CbrLEFE	false	-	myc tag:?-?(MINT-2836600)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39533	uniprotkb:Q12511	intact:EBI-2109|uniprotkb:D6VVZ3|ensemblfungi:YJL200C	intact:EBI-36488|uniprotkb:D6W2F1|ensemblfungi:YOR090C	psi-mi:acon2_yeast(display_long)|uniprotkb:ACO2(gene name)|psi-mi:ACO2(display_short)|uniprotkb:Aconitase 2(gene name synonym)|uniprotkb:J0327(orf name)|uniprotkb:YJL200C(locus name)	psi-mi:pdp1_yeast(display_long)|uniprotkb:PTC5(gene name)|psi-mi:PTC5(display_short)|uniprotkb:Phosphatase two C protein 5(gene name synonym)|uniprotkb:PPP1(gene name synonym)|uniprotkb:Protein phosphatase 2C homolog 5(gene name synonym)|uniprotkb:Protein phosphatase of PDH protein 1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex phosphatase 1(gene name synonym)|uniprotkb:YOR3157C(orf name)|uniprotkb:YOR090C(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Krause-Buchholz et al. (2006)	pubmed:16643908|imex:IM-11071|mint:MINT-5218575	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8501584|mint:MINT-2836557|imex:IM-11071-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012335.1|sgd:S000003736|dip:DIP-1376N|mint:P39533|ensemblfungi:YJL200C(gene)|ensemblfungi:YJL200C_mRNA(transcript)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:MINT-2836561(identity)	refseq:NP_014733.1|sgd:S000005616|mint:Q12511|dip:DIP-6439N|ensemblfungi:YOR090C(gene)|ensemblfungi:YOR090C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004741"("[pyruvate dehydrogenase (lipoamide)] phosphatase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1904184"(positive regulation of pyruvate dehydrogenase activity)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:MINT-2836560(identity)	-	comment:"Stoichiometry: 1.0"	crc64:07A5AF33FA72CC2A|comment:"Stoichiometry: 1.0"	figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/07/22	2014/10/16	rogid:lwfD8JbHha1FdR8PrYoI1k103FI559292	rogid:AepMamITZgBeuBC3Gni6DMkg35E559292	intact-crc:470BB8C8667DA7BB|rigid:0sbWgykmlWsjmTRnsv05CbrLEFE	false	-	ha tag:?-?(MINT-2836592)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)