#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16625	uniprotkb:P49674	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:"MI:0018"(two hybrid)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471542|mint:MINT-1892115|imex:IM-11166-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892116(identity)	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|mint:MINT-1892117(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	intact-crc:3A38FDA795705F7C|rigid:uUp/89r4dSU1FdNozCxm5qQ7GVY	false	tag:?-?(MINT-1892133)|binding-associated region:265-522(MINT-1892140)	binding-associated region:85-109(MINT-1892131)|tag:?-?(MINT-1892123)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16625	uniprotkb:O75385	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471637|mint:MINT-1892167|imex:IM-11166-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892176(identity)	refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-1892168(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606	intact-crc:5D44830341661919|rigid:QvLqHhcmA9e+IGbYB5x7ermYJNs	false	tag:?-?(MINT-1892177)|binding-associated region:265-522(MINT-1892184)	tag:?-?(MINT-1892174)|binding-associated region:953-1050(MINT-2791392)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16625	uniprotkb:Q13573	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short)	psi-mi:"MI:0018"(two hybrid)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471588|mint:MINT-1892144|imex:IM-11166-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892145(identity)	refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N|mint:MINT-1892155(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606	intact-crc:207A15247CABDC13|rigid:cyFJAGMisKQnUUq/uTtQ6kWxvr4	false	tag:?-?(MINT-1892153)|binding-associated region:265-522(MINT-1892146)	binding-associated region:1-195(MINT-2791366)|tag:?-?(MINT-1892163)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16625	uniprotkb:P49674	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:"MI:0096"(pull down)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471712|mint:MINT-1892205|imex:IM-11166-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892206(identity)	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|mint:MINT-1892216(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	intact-crc:00834A2636F977E7|rigid:uUp/89r4dSU1FdNozCxm5qQ7GVY	false	binding-associated region:265-522(MINT-1892207)|glutathione s tranferase tag:?-?(MINT-1892214)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q16625	uniprotkb:P48729	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|intact:EBI-11048253|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|ensembl:ENSP00000367074	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym)	psi-mi:"MI:0096"(pull down)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471733|mint:MINT-1892232|imex:IM-11166-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892233(identity)	refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|dip:DIP-40367N|ensembl:ENSG00000113712(gene)|ensembl:ENST00000377843(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051301"(cell division)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904424"(regulation of GTP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838|mint:MINT-1892242(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606	intact-crc:B83AD69E11DE5F95|rigid:didOPV3nzNwnRT+fQxlB8eHEb1k	false	binding-associated region:265-522(MINT-1892234)|glutathione s tranferase tag:?-?(MINT-1892240)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q16625	uniprotkb:P49674	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471784|mint:MINT-1892254|imex:IM-11166-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892255(identity)	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|mint:MINT-1892265(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	intact-crc:8C5566CB8ED008B2|rigid:uUp/89r4dSU1FdNozCxm5qQ7GVY	false	-	-	1	1	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q16625	uniprotkb:P49674	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:"MI:0428"(imaging technique)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471832|mint:MINT-1892281|imex:IM-11166-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892282(identity)	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|mint:MINT-1892288(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-uvec)|taxid:9606("Human Umbilical Vein Endothelial Cells (HUVEC)")	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	intact-crc:DEEA7393AACB587C|rigid:uUp/89r4dSU1FdNozCxm5qQ7GVY	false	-	-	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q16625	uniprotkb:P49674	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:"MI:0424"(protein kinase assay)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471869|mint:MINT-1892301|imex:IM-11166-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892302(identity)	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|mint:MINT-1892308(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	intact-crc:20000BF69E2325E0|rigid:uUp/89r4dSU1FdNozCxm5qQ7GVY	false	binding-associated region:265-474(MINT-2791481)|glutathione s tranferase tag:?-?(MINT-2791484)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16625	uniprotkb:P49674	intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4	intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074	psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)	psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short)	psi-mi:"MI:0424"(protein kinase assay)	McKenzie et al. (2006)	pubmed:16616143|imex:IM-11166|mint:MINT-5218515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8471890|mint:MINT-1892321|imex:IM-11166-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N|mint:MINT-1892322(identity)	refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|mint:MINT-1892327(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/26	2014/10/16	rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606	rogid:evdzz03ba4MFWavN9xRae/Wxwio9606	intact-crc:A1B2B717B857790E|rigid:uUp/89r4dSU1FdNozCxm5qQ7GVY	false	-	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)