#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11438 uniprotkb:Q8BGT0 intact:EBI-987439|uniprotkb:Q62020|ensembl:ENSMUSP00000033824 intact:EBI-987431|ensembl:ENSMUSP00000035516 psi-mi:lamp1_mouse(display_long)|uniprotkb:Lysosomal membrane glycoprotein A(gene name synonym)|uniprotkb:120 kDa lysosomal membrane glycoprotein(gene name synonym)|uniprotkb:LGP-120(gene name synonym)|uniprotkb:P2B(gene name synonym)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:Lamp1(gene name)|psi-mi:Lamp1(display_short)|uniprotkb:Lamp-1(gene name synonym) psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-987472|imex:IM-14514-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031447(gene)|ensembl:ENSMUST00000033824(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|refseq:NP_034814.2|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044194"(cytolytic granule)|go:"GO:0044754"(autolysosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0005829"(cytosol)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11438|rcsb pdb:5GV0|reactome:R-MMU-6798695|refseq:NP_001304282.1 ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 go:"GO:0005770"(late endosome)|go:"GO:0005764"(lysosome) - - figure legend:1A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus) - 2006/08/14 2014/10/16 rogid:34kBKJCpWncY9gLqL2lEx3Yn01I10090 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 intact-crc:96D8E325B9E2D6A9|rigid:ojE+bUODEFnJ7c8RwoHhPZh1ZS8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P11438 uniprotkb:Q8BGT0 intact:EBI-987439|uniprotkb:Q62020|ensembl:ENSMUSP00000033824 intact:EBI-987431|ensembl:ENSMUSP00000035516 psi-mi:lamp1_mouse(display_long)|uniprotkb:Lysosomal membrane glycoprotein A(gene name synonym)|uniprotkb:120 kDa lysosomal membrane glycoprotein(gene name synonym)|uniprotkb:LGP-120(gene name synonym)|uniprotkb:P2B(gene name synonym)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:Lamp1(gene name)|psi-mi:Lamp1(display_short)|uniprotkb:Lamp-1(gene name synonym) psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-987495|imex:IM-14514-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031447(gene)|ensembl:ENSMUST00000033824(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|refseq:NP_034814.2|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044194"(cytolytic granule)|go:"GO:0044754"(autolysosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0005829"(cytosol)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11438|rcsb pdb:5GV0|reactome:R-MMU-6798695|refseq:NP_001304282.1 ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 go:"GO:0005770"(late endosome)|go:"GO:0005764"(lysosome) - - delivery method:Q8BGT0 transfection;|comment:"Colocalisation required cotransfection with Clc-7 (O70496)"|figure legend:2C|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus) - 2006/08/14 2014/10/16 rogid:34kBKJCpWncY9gLqL2lEx3Yn01I10090 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 intact-crc:96BA73455B14E7FF|rigid:ojE+bUODEFnJ7c8RwoHhPZh1ZS8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:O70496 uniprotkb:Q8BGT0 intact:EBI-987482|ensembl:ENSMUSP00000035964 intact:EBI-987431|ensembl:ENSMUSP00000035516 psi-mi:clcn7_mouse(display_long)|uniprotkb:Clcn7(gene name)|psi-mi:Clcn7(display_short)|uniprotkb:Clc7(gene name synonym)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym) psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-987506|imex:IM-14514-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036636(gene)|ensembl:ENSMUST00000040729(transcript)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0009268"(response to pH)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|mint:O70496|reactome:R-MMU-2672351|refseq:NP_036060.1 ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 go:"GO:0005770"(late endosome)|go:"GO:0005764"(lysosome) - - delivery method:O70496 transfection; O70496 transfection;|figure legend:2D|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus) - 2006/08/14 2014/10/16 rogid:yygpg4lHjV3NltUHMraZrfeoizU10090 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 intact-crc:B04492449CAE6032|rigid:ixVFpdUy7uCqHiHgG5Wp5Squp+8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:O70496 uniprotkb:Q8BGT0 intact:EBI-987482|ensembl:ENSMUSP00000035964 intact:EBI-987431|ensembl:ENSMUSP00000035516 psi-mi:clcn7_mouse(display_long)|uniprotkb:Clcn7(gene name)|psi-mi:Clcn7(display_short)|uniprotkb:Clc7(gene name synonym)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym) psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-987534|imex:IM-14514-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036636(gene)|ensembl:ENSMUST00000040729(transcript)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0009268"(response to pH)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|mint:O70496|reactome:R-MMU-2672351|refseq:NP_036060.1 ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 psi-mi:"MI:0469"(intact) - - figure legend:3D|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2006/08/14 2014/10/16 rogid:yygpg4lHjV3NltUHMraZrfeoizU10090 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 intact-crc:0C8C6A5230C3BAB8|rigid:ixVFpdUy7uCqHiHgG5Wp5Squp+8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BGT0 uniprotkb:O70496 intact:EBI-987431|ensembl:ENSMUSP00000035516 intact:EBI-987482|ensembl:ENSMUSP00000035964 psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:clcn7_mouse(display_long)|uniprotkb:Clcn7(gene name)|psi-mi:Clcn7(display_short)|uniprotkb:Clc7(gene name synonym)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-987539|imex:IM-14514-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 ensembl:ENSMUSG00000036636(gene)|ensembl:ENSMUST00000040729(transcript)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0009268"(response to pH)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|mint:O70496|reactome:R-MMU-2672351|refseq:NP_036060.1 psi-mi:"MI:0469"(intact) - - figure legend:3D|comment:Molecular weight analysis suggested a cleaved, lysosomal Ostm1 fragment was pulled down by the Clcn7 antibody.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2006/08/14 2014/10/16 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 rogid:yygpg4lHjV3NltUHMraZrfeoizU10090 intact-crc:59B56184CAC9A666|rigid:ixVFpdUy7uCqHiHgG5Wp5Squp+8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O70496 uniprotkb:Q8BGT0 intact:EBI-987482|ensembl:ENSMUSP00000035964 intact:EBI-987431|ensembl:ENSMUSP00000035516 psi-mi:clcn7_mouse(display_long)|uniprotkb:Clcn7(gene name)|psi-mi:Clcn7(display_short)|uniprotkb:Clc7(gene name synonym)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym) psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-987546|imex:IM-14514-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036636(gene)|ensembl:ENSMUST00000040729(transcript)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0009268"(response to pH)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|mint:O70496|reactome:R-MMU-2672351|refseq:NP_036060.1 ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 psi-mi:"MI:0469"(intact) - - figure legend:S2|comment:Molecular weight analysis suggested a higher molecular weight form of Ostm1 was pulled down by the Clcn7 antibody.|delivery method:Q8BGT0 transfection;|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/14 2014/10/16 rogid:yygpg4lHjV3NltUHMraZrfeoizU10090 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 intact-crc:4545F6FEF967FB99|rigid:ixVFpdUy7uCqHiHgG5Wp5Squp+8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O70496 uniprotkb:Q8BGT0 intact:EBI-987482|ensembl:ENSMUSP00000035964 intact:EBI-987431|ensembl:ENSMUSP00000035516 psi-mi:clcn7_mouse(display_long)|uniprotkb:Clcn7(gene name)|psi-mi:Clcn7(display_short)|uniprotkb:Clc7(gene name synonym)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym) psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-987616|imex:IM-14514-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036636(gene)|ensembl:ENSMUST00000040729(transcript)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0009268"(response to pH)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|mint:O70496|reactome:R-MMU-2672351|refseq:NP_036060.1 ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 go:"GO:0005770"(late endosome)|go:"GO:0005764"(lysosome) - - figure legend:4A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-purkinje cell)|taxid:10090(Mus musculus) - 2006/08/14 2014/10/16 rogid:yygpg4lHjV3NltUHMraZrfeoizU10090 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 intact-crc:7A824E8C9AC9E672|rigid:ixVFpdUy7uCqHiHgG5Wp5Squp+8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:O70496 uniprotkb:Q8BGT0 intact:EBI-987482|ensembl:ENSMUSP00000035964 intact:EBI-987431|ensembl:ENSMUSP00000035516 psi-mi:clcn7_mouse(display_long)|uniprotkb:Clcn7(gene name)|psi-mi:Clcn7(display_short)|uniprotkb:Clc7(gene name synonym)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym) psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-987716|imex:IM-14514-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000036636(gene)|ensembl:ENSMUST00000040729(transcript)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0009268"(response to pH)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|mint:O70496|reactome:R-MMU-2672351|refseq:NP_036060.1 ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 go:"GO:0001726"(ruffle) - - figure legend:4C|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-osteoclast)|taxid:10090(Mouse osteoclast) - 2006/08/14 2014/10/16 rogid:yygpg4lHjV3NltUHMraZrfeoizU10090 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 intact-crc:9B7CCEFA1518A3CE|rigid:ixVFpdUy7uCqHiHgG5Wp5Squp+8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q8BGT0 uniprotkb:O70496 intact:EBI-987431|ensembl:ENSMUSP00000035516 intact:EBI-987482|ensembl:ENSMUSP00000035964 psi-mi:ostm1_mouse(display_long)|uniprotkb:Grey-lethal protein(gene name synonym)|uniprotkb:Ostm1(gene name)|psi-mi:Ostm1(display_short)|uniprotkb:Gl(gene name synonym)|uniprotkb:Chloride channel 7 beta subunit(gene name synonym) psi-mi:clcn7_mouse(display_long)|uniprotkb:Clcn7(gene name)|psi-mi:Clcn7(display_short)|uniprotkb:Clc7(gene name synonym)|uniprotkb:Chloride channel protein 7(gene name synonym)|uniprotkb:Chloride channel 7 alpha subunit(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lange et al. (2006) imex:IM-14514|pubmed:16525474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-987816|imex:IM-14514-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038280(gene)|ensembl:ENSMUST00000040718(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030316"(osteoclast differentiation)|interpro:IPR019172|reactome:R-MMU-2672351|refseq:NP_766004.1 ensembl:ENSMUSG00000036636(gene)|ensembl:ENSMUST00000040729(transcript)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0009268"(response to pH)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002249(Chloride channel CLC-7)|interpro:IPR014743(Chloride channel, core)|mint:O70496|reactome:R-MMU-2672351|refseq:NP_036060.1 go:"GO:0001726"(ruffle) - - figure legend:4D & 4E|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-osteoclast)|taxid:10090(Mouse osteoclast) - 2006/08/14 2014/10/16 rogid:+3jyZ9ycNub29k9QD5XVo0OMNyo10090 rogid:yygpg4lHjV3NltUHMraZrfeoizU10090 intact-crc:DDE13D9A5F6738DE|rigid:ixVFpdUy7uCqHiHgG5Wp5Squp+8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)