#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8WYL5 uniprotkb:P29751 intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713 intact:EBI-6268460 psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym) psi-mi:actb_rabit(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Yamamoto et al. (2006) pubmed:16513117|imex:IM-11461|mint:MINT-5218404 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8154328|mint:MINT-1788800|imex:IM-11461-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588|mint:MINT-1788802(identity) go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097433"(dense body)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|interpro:IPR020902|mint:P29751|refseq:NP_001095153.1|dip:DIP-2197N|mint:MINT-1788801(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/22 2014/10/16 rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606 rogid:pa9R+CHiXyOX/EJWS2R8uO2C0fw9986 intact-crc:BE555B861AD18D3B|rigid:UYDgKUWd4FXLuRcv9gsyz7leUdI false mutation disrupting interaction:915-915,916-916,917-917(MINT-1789098)|binding-associated region:915-1049(MINT-1788827)|tandem tag:?-?(MINT-1788807) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WYL5 uniprotkb:P29751 intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713 intact:EBI-6268460 psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym) psi-mi:actb_rabit(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Yamamoto et al. (2006) pubmed:16513117|imex:IM-11461|mint:MINT-5218404 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8155141|mint:MINT-1789078|imex:IM-11461-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588|mint:MINT-1789079(identity) go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097433"(dense body)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|interpro:IPR020902|mint:P29751|refseq:NP_001095153.1|dip:DIP-2197N|mint:MINT-1789089(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/22 2014/10/16 rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606 rogid:pa9R+CHiXyOX/EJWS2R8uO2C0fw9986 intact-crc:CDE0C0E7733F0A61|rigid:UYDgKUWd4FXLuRcv9gsyz7leUdI false tandem tag:?-?(MINT-1789087)|binding-associated region:1-461(MINT-1789080)|mutation disrupting interaction:458-458(MINT-1789096) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0113"(western blot)