#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0096"(pull down) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8051903|mint:MINT-2836489|imex:IM-11072-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836491(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836490(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2A|figure legend:F2D|figure legend:F5A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:7BA32407EC280A77|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false binding-associated region:489-599(MINT-2836513) binding-associated region:489-559(MINT-2836499)|glutathione s tranferase tag:n-n(MINT-2836493)|mutation disrupting interaction:506-506(MINT-2836502) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G3V9M2 uniprotkb:Q9R237-3 intact:EBI-8051970|intact:MINT-2836547|uniprotkb:Q3B8P9|ensembl:ENSRNOP00000052648 intact:EBI-8051913|intact:MINT-1500723 psi-mi:jip2_rat(display_long)|uniprotkb:Mapk8ip2(gene name)|psi-mi:Mapk8ip2(display_short)|uniprotkb:Ib2(gene name synonym)|uniprotkb:Islet-brain-2(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 2(gene name synonym)|uniprotkb:Jip2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 2(gene name synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0096"(pull down) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052000|mint:MINT-2836521|imex:IM-11072-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_001055248.1|refseq:XP_235565.5|rgd:1309727|ensembl:ENSRNOG00000032828(gene)|ensembl:ENSRNOT00000055792(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007254"(JNK cascade)|go:"GO:0007617"(mating behavior)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035176"(social behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046958"(nonassociative learning)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035637|mint:G3V9M2|mint:MINT-2836530(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836522(identity) - comment:"fragmentation type: fragment"|comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/26 2018/07/23 rogid:ws/TNP6AcXABhWwovlmWgpMiM7010116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:63B9644E45680B32|rigid:+jxFYlyAF6hCjXB5PGN8dZJ794M false glutathione s tranferase tag:?-?(MINT-2836544)|binding-associated region:618-668(MINT-2836537) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0400"(affinity technology) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8052034|mint:MINT-2836569|imex:IM-11072-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836570(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836575(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:SF1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:4759C278B3FE6FA6|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false binding-associated region:489-559(MINT-2836618)|mutation disrupting interaction:507-507(MINT-2836625)|mutation disrupting interaction:506-506(MINT-2836622)|his tag:?-?(MINT-2836616) binding-associated region:489-559(MINT-2836576)|mutation disrupting interaction:507-507(MINT-2836633)|his tag:?-?(MINT-2836581)|mutation disrupting interaction:506-506(MINT-2836629) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0067"(light scattering) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8052096|mint:MINT-2836640|imex:IM-11072-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836641(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836657(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:SF1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:49ADF8D7019F611E|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false binding-associated region:489-559(MINT-2836648) binding-associated region:489-559(MINT-2836664) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0114"(x-ray crystallography) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8052132|mint:MINT-2836681|imex:IM-11072-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836682(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836696(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:A6AB148D58CA4143|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false binding-associated region:494-553(MINT-2836683) binding-associated region:494-553(MINT-2836697) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052238|mint:MINT-2836711|imex:IM-11072-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836720(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836712(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F5B|figure legend:F2E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:0B9BFA52E4077428|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false green fluorescent protein tag:?-?(MINT-2836733)|mutation disrupting interaction:506-506(MINT-2836737)|binding-associated region:489-559(MINT-2836721) flag tag:?-?(MINT-2836729) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052269|mint:MINT-2836744|imex:IM-11072-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836759(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836745(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F5C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:B43B7314EDE79115|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false flag tag:?-?(MINT-2836764) green fluorescent protein tag:?-?(MINT-2836756)|mutation decreasing interaction:546-546(MINT-2836746) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052349|mint:MINT-2836798|imex:IM-11072-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836813(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836799(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F5B|figure legend:F5C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:8062BB2AAA84F747|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false flag tag:?-?(MINT-2836816)|mutation decreasing interaction:466-715(MINT-2836822) green fluorescent protein tag:?-?(MINT-2836810) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q9R237-3 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-8051913|intact:MINT-1500723 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052311|mint:MINT-2836773|imex:IM-11072-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836785(identity) intact:EBI-7936746(jip1_rat)|mint:MINT-2836774(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F5C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 intact-crc:43F7E8AF78474C9F|rigid:Sg8rRl/0iAZ0PzcLcqH/hMK+Hdw false flag tag:?-?(MINT-2836789) mutation decreasing interaction:506-506(MINT-2836775)|green fluorescent protein tag:?-?(MINT-2836781)|mutation decreasing interaction:507-507(MINT-2836794) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9R237-3 uniprotkb:Q16584 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-49961|uniprotkb:Q53H00|uniprotkb:Q59F06|uniprotkb:Q6P2G4|uniprotkb:B4DS76|ensembl:ENSP00000309597 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:m3k11_human(display_long)|uniprotkb:MAP3K11(gene name)|psi-mi:MAP3K11(display_short)|uniprotkb:Mixed lineage kinase 3(gene name synonym)|uniprotkb:Src-homology 3 domain-containing proline-rich kinase(gene name synonym)|uniprotkb:SPRK(gene name synonym)|uniprotkb:PTK1(gene name synonym)|uniprotkb:MLK3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052429|mint:MINT-2836830|imex:IM-11072-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836839(identity) refseq:NP_002410.1|ensembl:ENSG00000173327(gene)|ensembl:ENST00000309100(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|mint:Q16584|rcsb pdb:5K26|rcsb pdb:5K28|rcsb pdb:6AQB|rcsb pdb:6CQ7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-9013148|reactome:R-HSA-9013408|reactome:R-HSA-9649948|mint:MINT-2836831(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:njuMQIbuVFlWXNggegg3zYAKmS49606 intact-crc:8C4E617F9A7781AD|rigid:a7iNthgz1s5D1pY2XX24EAHcbSg false flag tag:?-?(MINT-2836846) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9R237-3 uniprotkb:P45983 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-286483|uniprotkb:Q15709|uniprotkb:Q15712|uniprotkb:Q15713|uniprotkb:B7ZLV4|uniprotkb:B5BTZ5|uniprotkb:Q308M2|uniprotkb:D3DX88|uniprotkb:D3DX92|ensembl:ENSP00000363304 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:mk08_human(display_long)|uniprotkb:MAPK8(gene name)|psi-mi:MAPK8(display_short)|uniprotkb:JNK1(gene name synonym)|uniprotkb:PRKM8(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 1(gene name synonym)|uniprotkb:JNK-46(gene name synonym)|uniprotkb:SAPK1(gene name synonym)|uniprotkb:Stress-activated protein kinase 1c(gene name synonym)|uniprotkb:SAPK1C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052446|mint:MINT-2836891|imex:IM-11072-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836892(identity) refseq:NP_620634.1|refseq:NP_620637.1|refseq:NP_001310231.1|refseq:NP_001310250.1|refseq:NP_001310251.1|refseq:NP_001310252.1|refseq:NP_001310253.1|refseq:NP_001310254.1|refseq:NP_001310255.1|refseq:NP_001310256.1|refseq:NP_001310257.1|refseq:NP_001310258.1|refseq:NP_001310259.1|refseq:NP_001310260.1|refseq:NP_001265476.1|refseq:NP_001265477.1|dip:DIP-249N|ensembl:ENSG00000107643(gene)|ensembl:ENST00000374189(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009411"(response to UV)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031343"(positive regulation of cell killing)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048511"(rhythmic process)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090045"(positive regulation of deacetylase activity)|go:"GO:0090398"(cellular senescence)|go:"GO:0097441"(basal dendrite)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900740"(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|go:"GO:1902595"(regulation of DNA replication origin binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:P45983|rcsb pdb:1UKH|rcsb pdb:1UKI|rcsb pdb:2G01|rcsb pdb:2GMX|rcsb pdb:2H96|rcsb pdb:2NO3|rcsb pdb:2XRW|rcsb pdb:2XS0|rcsb pdb:3ELJ|rcsb pdb:3O17|rcsb pdb:3O2M|rcsb pdb:3PZE|rcsb pdb:3V3V|rcsb pdb:3VUD|rcsb pdb:3VUG|rcsb pdb:3VUH|rcsb pdb:3VUI|rcsb pdb:3VUK|rcsb pdb:3VUL|rcsb pdb:3VUM|rcsb pdb:4AWI|rcsb pdb:4E73|rcsb pdb:4G1W|rcsb pdb:4HYS|rcsb pdb:4HYU|rcsb pdb:4IZY|rcsb pdb:4L7F|rcsb pdb:4QTD|rcsb pdb:4UX9|rcsb pdb:4YR8|rcsb pdb:5LW1|rcsb pdb:6F5E|rcsb pdb:6ZR5|reactome:R-HSA-111446|reactome:R-HSA-139910|reactome:R-HSA-193648|reactome:R-HSA-205043|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-450321|reactome:R-HSA-450341|reactome:R-HSA-5693565|reactome:R-HSA-9007892|reactome:R-HSA-9673324|mint:MINT-2836900(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:8FsGgIJWzsgWymaBqL5+0eQ/7qM9606 intact-crc:045BA92C0CDC53DF|rigid:/vlkGe6BQCrEmbkRu3KLSwBmQcw false flag tag:?-?(MINT-2836897) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9R237-3 uniprotkb:O14733 intact:EBI-8051913|intact:MINT-1500723 intact:EBI-492605|uniprotkb:O14648|uniprotkb:O14816|uniprotkb:O60452|uniprotkb:O60453|uniprotkb:Q1PG43|uniprotkb:Q8IY10|uniprotkb:B2R9S5|uniprotkb:D6W659|ensembl:ENSP00000381066 psi-mi:q9r237-3(display_long)|uniprotkb:Mapk8ip1(gene name)|psi-mi:Mapk8ip1(display_short)|uniprotkb:Ib1(gene name synonym)|uniprotkb:Islet-brain-1(gene name synonym)|uniprotkb:JIP-1-related protein(gene name synonym)|uniprotkb:JNK MAP kinase scaffold protein 1(gene name synonym)|uniprotkb:Jip1(gene name synonym)|uniprotkb:Mapk8ip(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 1(gene name synonym)|uniprotkb:JIP-1d(isoform synonym) psi-mi:mp2k7_human(display_long)|uniprotkb:MAPK/ERK kinase 7(gene name synonym)|uniprotkb:JNK-activating kinase 2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 2(gene name synonym)|uniprotkb:MAP2K7(gene name)|psi-mi:MAP2K7(display_short)|uniprotkb:JNKK2(gene name synonym)|uniprotkb:MKK7(gene name synonym)|uniprotkb:PRKMK7(gene name synonym)|uniprotkb:MEK7(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 4(gene name synonym)|uniprotkb:SKK4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kristensen et al. (2006) pubmed:16456539|imex:IM-11072|mint:MINT-5218291 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052475|mint:MINT-2836908|imex:IM-11072-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7936746(jip1_rat)|mint:MINT-2836915(identity) refseq:NP_660186.1|ensembl:ENSG00000076984(gene)|ensembl:ENST00000397979(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0009411"(response to UV)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:O14733|rcsb pdb:2DYL|rcsb pdb:3WZU|rcsb pdb:4UX9|rcsb pdb:5B2K|rcsb pdb:5B2L|rcsb pdb:5B2M|rcsb pdb:5Y8U|rcsb pdb:5Y90|rcsb pdb:5Z1D|rcsb pdb:5Z1E|rcsb pdb:6IB0|rcsb pdb:6IB2|go:"GO:0000187"(obsolete activation of MAPK activity)|rcsb pdb:6QFL|rcsb pdb:6QFR|rcsb pdb:6QFT|rcsb pdb:6QG4|rcsb pdb:6QG7|rcsb pdb:6QHO|rcsb pdb:6QHR|rcsb pdb:6YFZ|rcsb pdb:6YG0|rcsb pdb:6YG1|rcsb pdb:6YG2|rcsb pdb:6YG3|rcsb pdb:6YG4|rcsb pdb:6YG5|rcsb pdb:6YG6|rcsb pdb:6YG7|rcsb pdb:6YZ4|rcsb pdb:7CBX|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-5210891|reactome:R-HSA-450321|refseq:NP_001284484.1|refseq:NP_001284485.1|mint:MINT-2836909(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/07/26 2014/10/16 rogid:WUv55zsgKQKCKNX7uAKIJs0Qb4E10116 rogid:fEJqQ+bmZXzL9rSHk/Z01SQJFKM9606 intact-crc:1B6B8111764DCBD2|rigid:yDS4C9lxBOb8R5+HQdmRkWlmy40 false flag tag:?-?(MINT-2836917) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)