#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q06124	uniprotkb:Q08345	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	intact:EBI-711879|uniprotkb:Q14196|uniprotkb:Q16562|uniprotkb:Q5ST12|uniprotkb:Q9UD37|uniprotkb:B5A975|uniprotkb:B5A976|uniprotkb:Q2L6H3|uniprotkb:Q4LE50|uniprotkb:Q5ST11|uniprotkb:Q6NSK4|uniprotkb:Q9UD35|uniprotkb:Q9UD36|uniprotkb:Q9UDL2|uniprotkb:Q9UD86|uniprotkb:B7Z2K0|ensembl:ENSP00000318217|ensembl:ENSP00000365752|ensembl:ENSP00000372868|ensembl:ENSP00000383265|ensembl:ENSP00000383338|ensembl:ENSP00000383339|ensembl:ENSP00000391805|ensembl:ENSP00000397769|ensembl:ENSP00000401397|ensembl:ENSP00000405039|ensembl:ENSP00000414285|ensembl:ENSP00000448377|ensembl:ENSP00000449190|ensembl:ENSP00000449255|ensembl:ENSP00000449611	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:ddr1_human(display_long)|uniprotkb:Tyrosine kinase DDR(gene name synonym)|uniprotkb:Discoidin receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase CAK(gene name synonym)|uniprotkb:Cell adhesion kinase(gene name synonym)|uniprotkb:TRK E(gene name synonym)|uniprotkb:Protein-tyrosine kinase 3A(gene name synonym)|uniprotkb:HGK2(gene name synonym)|uniprotkb:CD167 antigen-like family member A(gene name synonym)|uniprotkb:Mammary carcinoma kinase 10(gene name synonym)|uniprotkb:DDR1(gene name)|psi-mi:DDR1(display_short)|uniprotkb:CAK(gene name synonym)|uniprotkb:EDDR1(gene name synonym)|uniprotkb:RTK6(gene name synonym)|uniprotkb:TRKE(gene name synonym)|uniprotkb:NEP(gene name synonym)|uniprotkb:NTRK4(gene name synonym)|uniprotkb:PTK3A(gene name synonym)|uniprotkb:Protein-tyrosine kinase RTK-6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Koo et al. (2006)	pubmed:16337946|imex:IM-11066|mint:MINT-5218086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7920822|mint:MINT-74882|imex:IM-11066-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-1500566(identity)	refseq:NP_001284581.1|refseq:NP_001284582.1|refseq:NP_001284583.1|refseq:NP_001189450.1|refseq:NP_001189451.1|refseq:NP_001189452.1|refseq:NP_001945.3|refseq:NP_054699.2|refseq:NP_054700.2|dip:DIP-39698N|ensembl:ENSG00000137332(gene)|ensembl:ENSG00000204580(gene)|ensembl:ENSG00000215522(gene)|ensembl:ENSG00000230456(gene)|ensembl:ENSG00000234078(gene)|ensembl:ENST00000324771(transcript)|ensembl:ENST00000376568(transcript)|ensembl:ENST00000383377(transcript)|ensembl:ENST00000400414(transcript)|ensembl:ENST00000400491(transcript)|ensembl:ENST00000400492(transcript)|ensembl:ENST00000412329(transcript)|ensembl:ENST00000429699(transcript)|ensembl:ENST00000430933(transcript)|ensembl:ENST00000449518(transcript)|ensembl:ENST00000452441(transcript)|ensembl:ENST00000548133(transcript)|ensembl:ENST00000550395(transcript)|ensembl:ENST00000552068(transcript)|ensembl:ENST00000553015(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0043583"(ear development)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0061564"(axon development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|rcsb pdb:3ZOS|rcsb pdb:4AG4|rcsb pdb:4BKJ|rcsb pdb:4CKR|rcsb pdb:5BVK|rcsb pdb:5BVN|rcsb pdb:5BVO|rcsb pdb:5BVW|rcsb pdb:5FDP|rcsb pdb:5FDX|rcsb pdb:6BRJ|rcsb pdb:6BSD|rcsb pdb:6FEW|rcsb pdb:6FEX|rcsb pdb:6FIL|rcsb pdb:6FIN|rcsb pdb:6FIO|rcsb pdb:6FIQ|rcsb pdb:6GWR|rcsb pdb:6HP9|rcsb pdb:6Y23|rcsb pdb:7BCM|rcsb pdb:7BE6|reactome:R-HSA-3000171|mint:MINT-1500559(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/17	2020/01/07	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	rogid:gveV0C3v43aJ6QWuK1zI8Ioo+Ns9606	intact-crc:8DCF3663FC2BAEA9|rigid:Sw4h9PpUwLnMvaFH48JVhRGURU4	false	tag:?-?(MINT-1500567)	tag:?-?(MINT-1500560)	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08345	uniprotkb:Q06124	intact:EBI-711879|uniprotkb:Q14196|uniprotkb:Q16562|uniprotkb:Q5ST12|uniprotkb:Q9UD37|uniprotkb:B5A975|uniprotkb:B5A976|uniprotkb:Q2L6H3|uniprotkb:Q4LE50|uniprotkb:Q5ST11|uniprotkb:Q6NSK4|uniprotkb:Q9UD35|uniprotkb:Q9UD36|uniprotkb:Q9UDL2|uniprotkb:Q9UD86|uniprotkb:B7Z2K0|ensembl:ENSP00000318217|ensembl:ENSP00000365752|ensembl:ENSP00000372868|ensembl:ENSP00000383265|ensembl:ENSP00000383338|ensembl:ENSP00000383339|ensembl:ENSP00000391805|ensembl:ENSP00000397769|ensembl:ENSP00000401397|ensembl:ENSP00000405039|ensembl:ENSP00000414285|ensembl:ENSP00000448377|ensembl:ENSP00000449190|ensembl:ENSP00000449255|ensembl:ENSP00000449611	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:ddr1_human(display_long)|uniprotkb:Tyrosine kinase DDR(gene name synonym)|uniprotkb:Discoidin receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase CAK(gene name synonym)|uniprotkb:Cell adhesion kinase(gene name synonym)|uniprotkb:TRK E(gene name synonym)|uniprotkb:Protein-tyrosine kinase 3A(gene name synonym)|uniprotkb:HGK2(gene name synonym)|uniprotkb:CD167 antigen-like family member A(gene name synonym)|uniprotkb:Mammary carcinoma kinase 10(gene name synonym)|uniprotkb:DDR1(gene name)|psi-mi:DDR1(display_short)|uniprotkb:CAK(gene name synonym)|uniprotkb:EDDR1(gene name synonym)|uniprotkb:RTK6(gene name synonym)|uniprotkb:TRKE(gene name synonym)|uniprotkb:NEP(gene name synonym)|uniprotkb:NTRK4(gene name synonym)|uniprotkb:PTK3A(gene name synonym)|uniprotkb:Protein-tyrosine kinase RTK-6(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Koo et al. (2006)	pubmed:16337946|imex:IM-11066|mint:MINT-5218086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7920841|mint:MINT-74883|imex:IM-11066-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284581.1|refseq:NP_001284582.1|refseq:NP_001284583.1|refseq:NP_001189450.1|refseq:NP_001189451.1|refseq:NP_001189452.1|refseq:NP_001945.3|refseq:NP_054699.2|refseq:NP_054700.2|dip:DIP-39698N|ensembl:ENSG00000137332(gene)|ensembl:ENSG00000204580(gene)|ensembl:ENSG00000215522(gene)|ensembl:ENSG00000230456(gene)|ensembl:ENSG00000234078(gene)|ensembl:ENST00000324771(transcript)|ensembl:ENST00000376568(transcript)|ensembl:ENST00000383377(transcript)|ensembl:ENST00000400414(transcript)|ensembl:ENST00000400491(transcript)|ensembl:ENST00000400492(transcript)|ensembl:ENST00000412329(transcript)|ensembl:ENST00000429699(transcript)|ensembl:ENST00000430933(transcript)|ensembl:ENST00000449518(transcript)|ensembl:ENST00000452441(transcript)|ensembl:ENST00000548133(transcript)|ensembl:ENST00000550395(transcript)|ensembl:ENST00000552068(transcript)|ensembl:ENST00000553015(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0043583"(ear development)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0061564"(axon development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|rcsb pdb:3ZOS|rcsb pdb:4AG4|rcsb pdb:4BKJ|rcsb pdb:4CKR|rcsb pdb:5BVK|rcsb pdb:5BVN|rcsb pdb:5BVO|rcsb pdb:5BVW|rcsb pdb:5FDP|rcsb pdb:5FDX|rcsb pdb:6BRJ|rcsb pdb:6BSD|rcsb pdb:6FEW|rcsb pdb:6FEX|rcsb pdb:6FIL|rcsb pdb:6FIN|rcsb pdb:6FIO|rcsb pdb:6FIQ|rcsb pdb:6GWR|rcsb pdb:6HP9|rcsb pdb:6Y23|rcsb pdb:7BCM|rcsb pdb:7BE6|reactome:R-HSA-3000171|mint:MINT-1500623(identity)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-1500632(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/17	2020/01/07	rogid:gveV0C3v43aJ6QWuK1zI8Ioo+Ns9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:41B8DE07AD64EDB5|rigid:Sw4h9PpUwLnMvaFH48JVhRGURU4	false	mutation decreasing interaction:740-740(MINT-1500624)|tag:?-?(MINT-1500626)	tag:?-?(MINT-1500633)	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08345	uniprotkb:O43639	intact:EBI-711879|uniprotkb:Q14196|uniprotkb:Q16562|uniprotkb:Q5ST12|uniprotkb:Q9UD37|uniprotkb:B5A975|uniprotkb:B5A976|uniprotkb:Q2L6H3|uniprotkb:Q4LE50|uniprotkb:Q5ST11|uniprotkb:Q6NSK4|uniprotkb:Q9UD35|uniprotkb:Q9UD36|uniprotkb:Q9UDL2|uniprotkb:Q9UD86|uniprotkb:B7Z2K0|ensembl:ENSP00000318217|ensembl:ENSP00000365752|ensembl:ENSP00000372868|ensembl:ENSP00000383265|ensembl:ENSP00000383338|ensembl:ENSP00000383339|ensembl:ENSP00000391805|ensembl:ENSP00000397769|ensembl:ENSP00000401397|ensembl:ENSP00000405039|ensembl:ENSP00000414285|ensembl:ENSP00000448377|ensembl:ENSP00000449190|ensembl:ENSP00000449255|ensembl:ENSP00000449611	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	psi-mi:ddr1_human(display_long)|uniprotkb:Tyrosine kinase DDR(gene name synonym)|uniprotkb:Discoidin receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase CAK(gene name synonym)|uniprotkb:Cell adhesion kinase(gene name synonym)|uniprotkb:TRK E(gene name synonym)|uniprotkb:Protein-tyrosine kinase 3A(gene name synonym)|uniprotkb:HGK2(gene name synonym)|uniprotkb:CD167 antigen-like family member A(gene name synonym)|uniprotkb:Mammary carcinoma kinase 10(gene name synonym)|uniprotkb:DDR1(gene name)|psi-mi:DDR1(display_short)|uniprotkb:CAK(gene name synonym)|uniprotkb:EDDR1(gene name synonym)|uniprotkb:RTK6(gene name synonym)|uniprotkb:TRKE(gene name synonym)|uniprotkb:NEP(gene name synonym)|uniprotkb:NTRK4(gene name synonym)|uniprotkb:PTK3A(gene name synonym)|uniprotkb:Protein-tyrosine kinase RTK-6(gene name synonym)	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koo et al. (2006)	pubmed:16337946|imex:IM-11066|mint:MINT-5218086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7920922|mint:MINT-74881|imex:IM-11066-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284581.1|refseq:NP_001284582.1|refseq:NP_001284583.1|refseq:NP_001189450.1|refseq:NP_001189451.1|refseq:NP_001189452.1|refseq:NP_001945.3|refseq:NP_054699.2|refseq:NP_054700.2|dip:DIP-39698N|ensembl:ENSG00000137332(gene)|ensembl:ENSG00000204580(gene)|ensembl:ENSG00000215522(gene)|ensembl:ENSG00000230456(gene)|ensembl:ENSG00000234078(gene)|ensembl:ENST00000324771(transcript)|ensembl:ENST00000376568(transcript)|ensembl:ENST00000383377(transcript)|ensembl:ENST00000400414(transcript)|ensembl:ENST00000400491(transcript)|ensembl:ENST00000400492(transcript)|ensembl:ENST00000412329(transcript)|ensembl:ENST00000429699(transcript)|ensembl:ENST00000430933(transcript)|ensembl:ENST00000449518(transcript)|ensembl:ENST00000452441(transcript)|ensembl:ENST00000548133(transcript)|ensembl:ENST00000550395(transcript)|ensembl:ENST00000552068(transcript)|ensembl:ENST00000553015(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0043583"(ear development)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0061564"(axon development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|rcsb pdb:3ZOS|rcsb pdb:4AG4|rcsb pdb:4BKJ|rcsb pdb:4CKR|rcsb pdb:5BVK|rcsb pdb:5BVN|rcsb pdb:5BVO|rcsb pdb:5BVW|rcsb pdb:5FDP|rcsb pdb:5FDX|rcsb pdb:6BRJ|rcsb pdb:6BSD|rcsb pdb:6FEW|rcsb pdb:6FEX|rcsb pdb:6FIL|rcsb pdb:6FIN|rcsb pdb:6FIO|rcsb pdb:6FIQ|rcsb pdb:6GWR|rcsb pdb:6HP9|rcsb pdb:6Y23|rcsb pdb:7BCM|rcsb pdb:7BE6|reactome:R-HSA-3000171|mint:MINT-1500581(identity)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|mint:MINT-1500588(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf-6)|taxid:9606(Homo sapiens)	-	2006/01/17	2014/10/16	rogid:gveV0C3v43aJ6QWuK1zI8Ioo+Ns9606	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	intact-crc:10AA3DFA9E62E7FE|rigid:ibjyZSIp5ys1SRmpx2jKqY0IC9Y	false	flag tag:?-?(MINT-1500582)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08345	uniprotkb:Q06124	intact:EBI-711879|uniprotkb:Q14196|uniprotkb:Q16562|uniprotkb:Q5ST12|uniprotkb:Q9UD37|uniprotkb:B5A975|uniprotkb:B5A976|uniprotkb:Q2L6H3|uniprotkb:Q4LE50|uniprotkb:Q5ST11|uniprotkb:Q6NSK4|uniprotkb:Q9UD35|uniprotkb:Q9UD36|uniprotkb:Q9UDL2|uniprotkb:Q9UD86|uniprotkb:B7Z2K0|ensembl:ENSP00000318217|ensembl:ENSP00000365752|ensembl:ENSP00000372868|ensembl:ENSP00000383265|ensembl:ENSP00000383338|ensembl:ENSP00000383339|ensembl:ENSP00000391805|ensembl:ENSP00000397769|ensembl:ENSP00000401397|ensembl:ENSP00000405039|ensembl:ENSP00000414285|ensembl:ENSP00000448377|ensembl:ENSP00000449190|ensembl:ENSP00000449255|ensembl:ENSP00000449611	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:ddr1_human(display_long)|uniprotkb:Tyrosine kinase DDR(gene name synonym)|uniprotkb:Discoidin receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase CAK(gene name synonym)|uniprotkb:Cell adhesion kinase(gene name synonym)|uniprotkb:TRK E(gene name synonym)|uniprotkb:Protein-tyrosine kinase 3A(gene name synonym)|uniprotkb:HGK2(gene name synonym)|uniprotkb:CD167 antigen-like family member A(gene name synonym)|uniprotkb:Mammary carcinoma kinase 10(gene name synonym)|uniprotkb:DDR1(gene name)|psi-mi:DDR1(display_short)|uniprotkb:CAK(gene name synonym)|uniprotkb:EDDR1(gene name synonym)|uniprotkb:RTK6(gene name synonym)|uniprotkb:TRKE(gene name synonym)|uniprotkb:NEP(gene name synonym)|uniprotkb:NTRK4(gene name synonym)|uniprotkb:PTK3A(gene name synonym)|uniprotkb:Protein-tyrosine kinase RTK-6(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koo et al. (2006)	pubmed:16337946|imex:IM-11066|mint:MINT-5218086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7920938|mint:MINT-74885|imex:IM-11066-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284581.1|refseq:NP_001284582.1|refseq:NP_001284583.1|refseq:NP_001189450.1|refseq:NP_001189451.1|refseq:NP_001189452.1|refseq:NP_001945.3|refseq:NP_054699.2|refseq:NP_054700.2|dip:DIP-39698N|ensembl:ENSG00000137332(gene)|ensembl:ENSG00000204580(gene)|ensembl:ENSG00000215522(gene)|ensembl:ENSG00000230456(gene)|ensembl:ENSG00000234078(gene)|ensembl:ENST00000324771(transcript)|ensembl:ENST00000376568(transcript)|ensembl:ENST00000383377(transcript)|ensembl:ENST00000400414(transcript)|ensembl:ENST00000400491(transcript)|ensembl:ENST00000400492(transcript)|ensembl:ENST00000412329(transcript)|ensembl:ENST00000429699(transcript)|ensembl:ENST00000430933(transcript)|ensembl:ENST00000449518(transcript)|ensembl:ENST00000452441(transcript)|ensembl:ENST00000548133(transcript)|ensembl:ENST00000550395(transcript)|ensembl:ENST00000552068(transcript)|ensembl:ENST00000553015(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0043583"(ear development)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0061564"(axon development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|rcsb pdb:3ZOS|rcsb pdb:4AG4|rcsb pdb:4BKJ|rcsb pdb:4CKR|rcsb pdb:5BVK|rcsb pdb:5BVN|rcsb pdb:5BVO|rcsb pdb:5BVW|rcsb pdb:5FDP|rcsb pdb:5FDX|rcsb pdb:6BRJ|rcsb pdb:6BSD|rcsb pdb:6FEW|rcsb pdb:6FEX|rcsb pdb:6FIL|rcsb pdb:6FIN|rcsb pdb:6FIO|rcsb pdb:6FIQ|rcsb pdb:6GWR|rcsb pdb:6HP9|rcsb pdb:6Y23|rcsb pdb:7BCM|rcsb pdb:7BE6|reactome:R-HSA-3000171|mint:MINT-1500666(identity)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-1500673(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf-6)|taxid:9606(Homo sapiens)	-	2006/01/17	2020/01/07	rogid:gveV0C3v43aJ6QWuK1zI8Ioo+Ns9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:F274BC48B80C53A9|rigid:Sw4h9PpUwLnMvaFH48JVhRGURU4	false	flag tag:?-?(MINT-1500667)	-	1	1	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08345	uniprotkb:O43639	intact:EBI-711879|uniprotkb:Q14196|uniprotkb:Q16562|uniprotkb:Q5ST12|uniprotkb:Q9UD37|uniprotkb:B5A975|uniprotkb:B5A976|uniprotkb:Q2L6H3|uniprotkb:Q4LE50|uniprotkb:Q5ST11|uniprotkb:Q6NSK4|uniprotkb:Q9UD35|uniprotkb:Q9UD36|uniprotkb:Q9UDL2|uniprotkb:Q9UD86|uniprotkb:B7Z2K0|ensembl:ENSP00000318217|ensembl:ENSP00000365752|ensembl:ENSP00000372868|ensembl:ENSP00000383265|ensembl:ENSP00000383338|ensembl:ENSP00000383339|ensembl:ENSP00000391805|ensembl:ENSP00000397769|ensembl:ENSP00000401397|ensembl:ENSP00000405039|ensembl:ENSP00000414285|ensembl:ENSP00000448377|ensembl:ENSP00000449190|ensembl:ENSP00000449255|ensembl:ENSP00000449611	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	psi-mi:ddr1_human(display_long)|uniprotkb:Tyrosine kinase DDR(gene name synonym)|uniprotkb:Discoidin receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase CAK(gene name synonym)|uniprotkb:Cell adhesion kinase(gene name synonym)|uniprotkb:TRK E(gene name synonym)|uniprotkb:Protein-tyrosine kinase 3A(gene name synonym)|uniprotkb:HGK2(gene name synonym)|uniprotkb:CD167 antigen-like family member A(gene name synonym)|uniprotkb:Mammary carcinoma kinase 10(gene name synonym)|uniprotkb:DDR1(gene name)|psi-mi:DDR1(display_short)|uniprotkb:CAK(gene name synonym)|uniprotkb:EDDR1(gene name synonym)|uniprotkb:RTK6(gene name synonym)|uniprotkb:TRKE(gene name synonym)|uniprotkb:NEP(gene name synonym)|uniprotkb:NTRK4(gene name synonym)|uniprotkb:PTK3A(gene name synonym)|uniprotkb:Protein-tyrosine kinase RTK-6(gene name synonym)	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Koo et al. (2006)	pubmed:16337946|imex:IM-11066|mint:MINT-5218086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7921009|mint:MINT-74879|imex:IM-11066-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284581.1|refseq:NP_001284582.1|refseq:NP_001284583.1|refseq:NP_001189450.1|refseq:NP_001189451.1|refseq:NP_001189452.1|refseq:NP_001945.3|refseq:NP_054699.2|refseq:NP_054700.2|dip:DIP-39698N|ensembl:ENSG00000137332(gene)|ensembl:ENSG00000204580(gene)|ensembl:ENSG00000215522(gene)|ensembl:ENSG00000230456(gene)|ensembl:ENSG00000234078(gene)|ensembl:ENST00000324771(transcript)|ensembl:ENST00000376568(transcript)|ensembl:ENST00000383377(transcript)|ensembl:ENST00000400414(transcript)|ensembl:ENST00000400491(transcript)|ensembl:ENST00000400492(transcript)|ensembl:ENST00000412329(transcript)|ensembl:ENST00000429699(transcript)|ensembl:ENST00000430933(transcript)|ensembl:ENST00000449518(transcript)|ensembl:ENST00000452441(transcript)|ensembl:ENST00000548133(transcript)|ensembl:ENST00000550395(transcript)|ensembl:ENST00000552068(transcript)|ensembl:ENST00000553015(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0043583"(ear development)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0061564"(axon development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|rcsb pdb:3ZOS|rcsb pdb:4AG4|rcsb pdb:4BKJ|rcsb pdb:4CKR|rcsb pdb:5BVK|rcsb pdb:5BVN|rcsb pdb:5BVO|rcsb pdb:5BVW|rcsb pdb:5FDP|rcsb pdb:5FDX|rcsb pdb:6BRJ|rcsb pdb:6BSD|rcsb pdb:6FEW|rcsb pdb:6FEX|rcsb pdb:6FIL|rcsb pdb:6FIN|rcsb pdb:6FIO|rcsb pdb:6FIQ|rcsb pdb:6GWR|rcsb pdb:6HP9|rcsb pdb:6Y23|rcsb pdb:7BCM|rcsb pdb:7BE6|reactome:R-HSA-3000171|mint:MINT-1500599(identity)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|mint:MINT-1500609(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2006/01/17	2014/10/16	rogid:gveV0C3v43aJ6QWuK1zI8Ioo+Ns9606	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	intact-crc:DB89C9DEAF1097A4|rigid:ibjyZSIp5ys1SRmpx2jKqY0IC9Y	false	tag:?-?(MINT-1500603)|binding-associated region:431-913(MINT-1500600)	tag:?-?(MINT-1500613)|binding-associated region:269-380(MINT-1500610)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43639	uniprotkb:Q08345	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	intact:EBI-711879|uniprotkb:Q14196|uniprotkb:Q16562|uniprotkb:Q5ST12|uniprotkb:Q9UD37|uniprotkb:B5A975|uniprotkb:B5A976|uniprotkb:Q2L6H3|uniprotkb:Q4LE50|uniprotkb:Q5ST11|uniprotkb:Q6NSK4|uniprotkb:Q9UD35|uniprotkb:Q9UD36|uniprotkb:Q9UDL2|uniprotkb:Q9UD86|uniprotkb:B7Z2K0|ensembl:ENSP00000318217|ensembl:ENSP00000365752|ensembl:ENSP00000372868|ensembl:ENSP00000383265|ensembl:ENSP00000383338|ensembl:ENSP00000383339|ensembl:ENSP00000391805|ensembl:ENSP00000397769|ensembl:ENSP00000401397|ensembl:ENSP00000405039|ensembl:ENSP00000414285|ensembl:ENSP00000448377|ensembl:ENSP00000449190|ensembl:ENSP00000449255|ensembl:ENSP00000449611	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:ddr1_human(display_long)|uniprotkb:Tyrosine kinase DDR(gene name synonym)|uniprotkb:Discoidin receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase CAK(gene name synonym)|uniprotkb:Cell adhesion kinase(gene name synonym)|uniprotkb:TRK E(gene name synonym)|uniprotkb:Protein-tyrosine kinase 3A(gene name synonym)|uniprotkb:HGK2(gene name synonym)|uniprotkb:CD167 antigen-like family member A(gene name synonym)|uniprotkb:Mammary carcinoma kinase 10(gene name synonym)|uniprotkb:DDR1(gene name)|psi-mi:DDR1(display_short)|uniprotkb:CAK(gene name synonym)|uniprotkb:EDDR1(gene name synonym)|uniprotkb:RTK6(gene name synonym)|uniprotkb:TRKE(gene name synonym)|uniprotkb:NEP(gene name synonym)|uniprotkb:NTRK4(gene name synonym)|uniprotkb:PTK3A(gene name synonym)|uniprotkb:Protein-tyrosine kinase RTK-6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koo et al. (2006)	pubmed:16337946|imex:IM-11066|mint:MINT-5218086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7921053|mint:MINT-74880|imex:IM-11066-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|mint:MINT-1500652(identity)	refseq:NP_001284581.1|refseq:NP_001284582.1|refseq:NP_001284583.1|refseq:NP_001189450.1|refseq:NP_001189451.1|refseq:NP_001189452.1|refseq:NP_001945.3|refseq:NP_054699.2|refseq:NP_054700.2|dip:DIP-39698N|ensembl:ENSG00000137332(gene)|ensembl:ENSG00000204580(gene)|ensembl:ENSG00000215522(gene)|ensembl:ENSG00000230456(gene)|ensembl:ENSG00000234078(gene)|ensembl:ENST00000324771(transcript)|ensembl:ENST00000376568(transcript)|ensembl:ENST00000383377(transcript)|ensembl:ENST00000400414(transcript)|ensembl:ENST00000400491(transcript)|ensembl:ENST00000400492(transcript)|ensembl:ENST00000412329(transcript)|ensembl:ENST00000429699(transcript)|ensembl:ENST00000430933(transcript)|ensembl:ENST00000449518(transcript)|ensembl:ENST00000452441(transcript)|ensembl:ENST00000548133(transcript)|ensembl:ENST00000550395(transcript)|ensembl:ENST00000552068(transcript)|ensembl:ENST00000553015(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0043583"(ear development)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0061564"(axon development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|rcsb pdb:3ZOS|rcsb pdb:4AG4|rcsb pdb:4BKJ|rcsb pdb:4CKR|rcsb pdb:5BVK|rcsb pdb:5BVN|rcsb pdb:5BVO|rcsb pdb:5BVW|rcsb pdb:5FDP|rcsb pdb:5FDX|rcsb pdb:6BRJ|rcsb pdb:6BSD|rcsb pdb:6FEW|rcsb pdb:6FEX|rcsb pdb:6FIL|rcsb pdb:6FIN|rcsb pdb:6FIO|rcsb pdb:6FIQ|rcsb pdb:6GWR|rcsb pdb:6HP9|rcsb pdb:6Y23|rcsb pdb:7BCM|rcsb pdb:7BE6|reactome:R-HSA-3000171|mint:MINT-1500645(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/17	2014/10/16	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	rogid:gveV0C3v43aJ6QWuK1zI8Ioo+Ns9606	intact-crc:F156ACF92F5EA428|rigid:ibjyZSIp5ys1SRmpx2jKqY0IC9Y	false	binding-associated region:269-380(MINT-1500653)|glutathione s tranferase tag:?-?(MINT-1500656)	tag:?-?(MINT-1500646)	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08345	uniprotkb:Q06124	intact:EBI-711879|uniprotkb:Q14196|uniprotkb:Q16562|uniprotkb:Q5ST12|uniprotkb:Q9UD37|uniprotkb:B5A975|uniprotkb:B5A976|uniprotkb:Q2L6H3|uniprotkb:Q4LE50|uniprotkb:Q5ST11|uniprotkb:Q6NSK4|uniprotkb:Q9UD35|uniprotkb:Q9UD36|uniprotkb:Q9UDL2|uniprotkb:Q9UD86|uniprotkb:B7Z2K0|ensembl:ENSP00000318217|ensembl:ENSP00000365752|ensembl:ENSP00000372868|ensembl:ENSP00000383265|ensembl:ENSP00000383338|ensembl:ENSP00000383339|ensembl:ENSP00000391805|ensembl:ENSP00000397769|ensembl:ENSP00000401397|ensembl:ENSP00000405039|ensembl:ENSP00000414285|ensembl:ENSP00000448377|ensembl:ENSP00000449190|ensembl:ENSP00000449255|ensembl:ENSP00000449611	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:ddr1_human(display_long)|uniprotkb:Tyrosine kinase DDR(gene name synonym)|uniprotkb:Discoidin receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase CAK(gene name synonym)|uniprotkb:Cell adhesion kinase(gene name synonym)|uniprotkb:TRK E(gene name synonym)|uniprotkb:Protein-tyrosine kinase 3A(gene name synonym)|uniprotkb:HGK2(gene name synonym)|uniprotkb:CD167 antigen-like family member A(gene name synonym)|uniprotkb:Mammary carcinoma kinase 10(gene name synonym)|uniprotkb:DDR1(gene name)|psi-mi:DDR1(display_short)|uniprotkb:CAK(gene name synonym)|uniprotkb:EDDR1(gene name synonym)|uniprotkb:RTK6(gene name synonym)|uniprotkb:TRKE(gene name synonym)|uniprotkb:NEP(gene name synonym)|uniprotkb:NTRK4(gene name synonym)|uniprotkb:PTK3A(gene name synonym)|uniprotkb:Protein-tyrosine kinase RTK-6(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Koo et al. (2006)	pubmed:16337946|imex:IM-11066|mint:MINT-5218086	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7921108|mint:MINT-8035995|imex:IM-11066-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284581.1|refseq:NP_001284582.1|refseq:NP_001284583.1|refseq:NP_001189450.1|refseq:NP_001189451.1|refseq:NP_001189452.1|refseq:NP_001945.3|refseq:NP_054699.2|refseq:NP_054700.2|dip:DIP-39698N|ensembl:ENSG00000137332(gene)|ensembl:ENSG00000204580(gene)|ensembl:ENSG00000215522(gene)|ensembl:ENSG00000230456(gene)|ensembl:ENSG00000234078(gene)|ensembl:ENST00000324771(transcript)|ensembl:ENST00000376568(transcript)|ensembl:ENST00000383377(transcript)|ensembl:ENST00000400414(transcript)|ensembl:ENST00000400491(transcript)|ensembl:ENST00000400492(transcript)|ensembl:ENST00000412329(transcript)|ensembl:ENST00000429699(transcript)|ensembl:ENST00000430933(transcript)|ensembl:ENST00000449518(transcript)|ensembl:ENST00000452441(transcript)|ensembl:ENST00000548133(transcript)|ensembl:ENST00000550395(transcript)|ensembl:ENST00000552068(transcript)|ensembl:ENST00000553015(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038062"(protein tyrosine kinase collagen receptor activity)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0043583"(ear development)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0061564"(axon development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR034299|rcsb pdb:3ZOS|rcsb pdb:4AG4|rcsb pdb:4BKJ|rcsb pdb:4CKR|rcsb pdb:5BVK|rcsb pdb:5BVN|rcsb pdb:5BVO|rcsb pdb:5BVW|rcsb pdb:5FDP|rcsb pdb:5FDX|rcsb pdb:6BRJ|rcsb pdb:6BSD|rcsb pdb:6FEW|rcsb pdb:6FEX|rcsb pdb:6FIL|rcsb pdb:6FIN|rcsb pdb:6FIO|rcsb pdb:6FIQ|rcsb pdb:6GWR|rcsb pdb:6HP9|rcsb pdb:6Y23|rcsb pdb:7BCM|rcsb pdb:7BE6|reactome:R-HSA-3000171|mint:MINT-8035999(identity)|uniprotkb:Q08345(original identifier)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-8035996(identity)|uniprotkb:Q06124(original identifier)	-	-	-	comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-3(unknown)|taxid:-3(Unknown)	-	2006/01/17	2020/01/07	rogid:gveV0C3v43aJ6QWuK1zI8Ioo+Ns9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:FE25F94A1AD31F84|rigid:Sw4h9PpUwLnMvaFH48JVhRGURU4	false	phosphorylated residue:740-740(MINT-8036004)|binding-associated region:733-746(MINT-8036002)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)