#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9QX74	uniprotkb:P26433	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	intact:EBI-961694	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:sl9a3_rat(display_long)|uniprotkb:Slc9a3(gene name)|psi-mi:Slc9a3(display_short)|uniprotkb:Nhe3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Han et al. (2006)	imex:IM-14537|pubmed:16293618	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-961714|imex:IM-14537-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1	go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0031982"(vesicle)|rgd:3720|refseq:NP_036786.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986	psi-mi:"MI:0469"(intact)	-	-	figure legend:S1|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/04	2014/10/16	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	rogid:7bSUDMNq7pX8lDlSPsoOAmVipD810116	intact-crc:5E2459CE78937443|rigid:qJ21aPPzzAbiv7H3WwDDhzblVbY	false	sufficient binding region:248..248-342..342(IPR001478)	sufficient binding region:800-831	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-961885	uniprotkb:Q9QX74	-	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:slc9a3(display_short)|psi-mi:EBI-961885(display_long)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Han et al. (2006)	imex:IM-14537|pubmed:16293618	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-961876|imex:IM-14537-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	figure legend:1A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-ps120)|taxid:10029(Cricetulus griseus ps120 fibroblasts)	-	2006/07/04	2014/10/16	-	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	intact-crc:CCC2CB7A18949FFE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QX74	uniprotkb:P26433	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	intact:EBI-961694	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:sl9a3_rat(display_long)|uniprotkb:Slc9a3(gene name)|psi-mi:Slc9a3(display_short)|uniprotkb:Nhe3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Han et al. (2006)	imex:IM-14537|pubmed:16293618	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-961924|imex:IM-14537-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1	go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0031982"(vesicle)|rgd:3720|refseq:NP_036786.1|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR018410|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|reactome:R-RNO-425986	psi-mi:"MI:0469"(intact)	-	-	figure legend:1B|kinetics:Association rate constant=3.2x10EXP-4M-1s-1|kinetics:Dissociation rate constant=3.7x10EXP-3s-1|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/04	2014/10/16	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	rogid:7bSUDMNq7pX8lDlSPsoOAmVipD810116	intact-crc:8E984E431EA63C06|rigid:qJ21aPPzzAbiv7H3WwDDhzblVbY	false	sufficient binding region:248..248-342..342|his tag:?-?	sufficient binding region:800-831	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)