#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35739	uniprotkb:Q9EQG6	intact:EBI-976667|ensembl:ENSRNOP00000018961	intact:EBI-976654|uniprotkb:Q9ERD4	psi-mi:ntrk1_rat(display_long)|uniprotkb:Neurotrophic tyrosine kinase receptor type 1(gene name synonym)|uniprotkb:p140-TrkA(gene name synonym)|uniprotkb:Slow nerve growth factor receptor(gene name synonym)|uniprotkb:Ntrk1(gene name)|psi-mi:Ntrk1(display_short)|uniprotkb:Trk(gene name synonym)|uniprotkb:Trka(gene name synonym)	psi-mi:kdis_rat(display_long)|uniprotkb:Kidins220(gene name)|psi-mi:Kidins220(display_short)|uniprotkb:Arms(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Arevalo et al. (2006)	imex:IM-14422|pubmed:16284401|mint:MINT-7149178	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976690|imex:IM-14422-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-RNO-177504|reactome:R-RNO-187042|reactome:R-RNO-198203|ensembl:ENSRNOG00000013953(gene)|ensembl:ENSRNOT00000018961(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005030"(neurotrophin receptor activity)|go:"GO:0005166"(neurotrophin p75 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0004675"(transmembrane receptor protein serine/threonine kinase activity)|go:"GO:0009314"(response to radiation)|go:"GO:0009986"(cell surface)|go:"GO:0010465"(nerve growth factor receptor activity)|go:"GO:0010623"(programmed cell death involved in cell development)|rgd:620144|refseq:NP_067600.1|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035094"(response to nicotine)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0019900"(kinase binding)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048678"(response to axon injury)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060384"(innervation)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0061368"(behavioral response to formalin induced pain)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020461|interpro:IPR020635|interpro:IPR020777|interpro:IPR031635|interpro:IPR032675|interpro:IPR036179|mint:P35739|reactome:R-RNO-170968|reactome:R-RNO-170984|dip:DIP-5716N	go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0005770"(late endosome)|go:"GO:0001701"(in utero embryonic development)|rgd:619949|refseq:NP_446247.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-RNO-9696270|reactome:R-RNO-9696273|interpro:IPR036770|rcsb pdb:7D6F|reactome:R-RNO-170984	psi-mi:"MI:0469"(intact)	-	-	comment:Source of TrkA assumed from previous work by the author|figure legend:1B|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/07/25	2014/10/16	rogid:jpLQn/DChXe097KfGi+Ag5nRMkw10116	rogid:HK13TDKSZUJSzqHU7w2EXSUoa1M10116	intact-crc:666C1E756A840C30|rigid:QQ/n9yVNsa5AGEAs6OqzPxyN6iA	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EQG6	uniprotkb:P46109	intact:EBI-976654|uniprotkb:Q9ERD4	intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646	psi-mi:kdis_rat(display_long)|uniprotkb:Kidins220(gene name)|psi-mi:Kidins220(display_short)|uniprotkb:Arms(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short)	psi-mi:"MI:0096"(pull down)	Arevalo et al. (2006)	imex:IM-14422|pubmed:16284401|mint:MINT-7149178	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976812|imex:IM-14422-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0005770"(late endosome)|go:"GO:0001701"(in utero embryonic development)|rgd:619949|refseq:NP_446247.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-RNO-9696270|reactome:R-RNO-9696273|interpro:IPR036770|rcsb pdb:7D6F|reactome:R-RNO-170984	refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631	psi-mi:"MI:0469"(intact)	-	-	figure legend:2B|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/25	2014/10/16	rogid:HK13TDKSZUJSzqHU7w2EXSUoa1M10116	rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606	intact-crc:2C89AD6EDAF7E3FE|rigid:csDje9xuWjkVrfBK4S8yERd7yh8	false	glutathione s tranferase tag:?-?|sufficient binding region:1056-1087|necessary binding region:1088-1092|mutation decreasing interaction:1095-1095	35s radiolabel:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U2U2	uniprotkb:Q9EQG6	intact:EBI-976752|ensembl:ENSRNOP00000002552	intact:EBI-976654|uniprotkb:Q9ERD4	psi-mi:crkl_rat(display_long)|uniprotkb:Crkl(gene name)|psi-mi:Crkl(display_short)	psi-mi:kdis_rat(display_long)|uniprotkb:Kidins220(gene name)|psi-mi:Kidins220(display_short)|uniprotkb:Arms(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Arevalo et al. (2006)	imex:IM-14422|pubmed:16284401|mint:MINT-7149178	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976832|imex:IM-14422-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000001868(gene)|ensembl:ENSRNOT00000002552(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007416"(synapse assembly)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR036860|reactome:R-RNO-170968|reactome:R-RNO-186763|reactome:R-RNO-8875555|reactome:R-RNO-8875656|reactome:R-RNO-9027284|reactome:R-RNO-912631|rgd:1308531|refseq:NP_001008285.1|refseq:XP_003751143.1	go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0005770"(late endosome)|go:"GO:0001701"(in utero embryonic development)|rgd:619949|refseq:NP_446247.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-RNO-9696270|reactome:R-RNO-9696273|interpro:IPR036770|rcsb pdb:7D6F|reactome:R-RNO-170984	psi-mi:"MI:0469"(intact)	-	-	figure legend:2C|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/25	2014/10/16	rogid:qKYIGtIILs2tDhFwPBMnFyDpJZc10116	rogid:HK13TDKSZUJSzqHU7w2EXSUoa1M10116	intact-crc:F48472E5EC94D3AE|rigid:ehRD6T58vtxRN2KASvqxdH2JdcY	false	mutation decreasing interaction:39-39	35s radiolabel:?-?|sufficient binding region:1056-1087|necessary binding region:1088-1092|mutation decreasing interaction:1095-1095|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EQG6	uniprotkb:Q13905	intact:EBI-976654|uniprotkb:Q9ERD4	intact:EBI-976876|ensembl:ENSP00000361263|uniprotkb:Q5JUE4|uniprotkb:Q68DL3|uniprotkb:Q8IV73|intact:EBI-11072310	psi-mi:kdis_rat(display_long)|uniprotkb:Kidins220(gene name)|psi-mi:Kidins220(display_short)|uniprotkb:Arms(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	psi-mi:rpgf1_human(display_long)|uniprotkb:Guanine nucleotide-releasing factor 2(gene name synonym)|uniprotkb:Protein C3G(gene name synonym)|uniprotkb:CRK SH3-binding GNRP(gene name synonym)|uniprotkb:RAPGEF1(gene name)|psi-mi:RAPGEF1(display_short)|uniprotkb:GRF2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Arevalo et al. (2006)	imex:IM-14422|pubmed:16284401|mint:MINT-7149178	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976912|imex:IM-14422-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0005770"(late endosome)|go:"GO:0001701"(in utero embryonic development)|rgd:619949|refseq:NP_446247.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-RNO-9696270|reactome:R-RNO-9696273|interpro:IPR036770|rcsb pdb:7D6F|reactome:R-RNO-170984	go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|ensembl:ENSG00000107263(gene)|ensembl:ENST00000372189(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR019804|interpro:IPR023578|interpro:IPR036964|mint:Q13905|rcsb pdb:5L23|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-9013423|reactome:R-HSA-9027284|reactome:R-HSA-912631|refseq:NP_005303.2|refseq:NP_001291204.1|refseq:NP_941372.1|dip:DIP-29392N	psi-mi:"MI:0469"(intact)	-	-	figure legend:7A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/25	2014/10/16	rogid:HK13TDKSZUJSzqHU7w2EXSUoa1M10116	rogid:WZp5ILq2aJ9P07oY9ieRfytDL0w9606	intact-crc:0B30F9D46917C7DB|rigid:sbXfJTwkfgDYtwbG7b+PqFbZnhQ	false	glutathione s tranferase tag:?-?|sufficient binding region:1056-1087|necessary binding region:1088-1092|mutation decreasing interaction:1095-1095	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EQG6	uniprotkb:P46109	intact:EBI-976654|uniprotkb:Q9ERD4	intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646	psi-mi:kdis_rat(display_long)|uniprotkb:Kidins220(gene name)|psi-mi:Kidins220(display_short)|uniprotkb:Arms(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short)	psi-mi:"MI:0096"(pull down)	Arevalo et al. (2006)	imex:IM-14422|pubmed:16284401|mint:MINT-7149178	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976912|imex:IM-14422-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0005770"(late endosome)|go:"GO:0001701"(in utero embryonic development)|rgd:619949|refseq:NP_446247.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-RNO-9696270|reactome:R-RNO-9696273|interpro:IPR036770|rcsb pdb:7D6F|reactome:R-RNO-170984	refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631	psi-mi:"MI:0469"(intact)	-	-	figure legend:7A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/25	2014/10/16	rogid:HK13TDKSZUJSzqHU7w2EXSUoa1M10116	rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606	intact-crc:0B30F9D46917C7DB|rigid:sbXfJTwkfgDYtwbG7b+PqFbZnhQ	false	glutathione s tranferase tag:?-?|sufficient binding region:1056-1087|necessary binding region:1088-1092|mutation decreasing interaction:1095-1095	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-998408	uniprotkb:Q9EQG6	-	intact:EBI-976654|uniprotkb:Q9ERD4	psi-mi:eea1(display_short)|psi-mi:EBI-998408(display_long)	psi-mi:kdis_rat(display_long)|uniprotkb:Kidins220(gene name)|psi-mi:Kidins220(display_short)|uniprotkb:Arms(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Arevalo et al. (2006)	imex:IM-14422|pubmed:16284401|mint:MINT-7149178	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-998402|imex:IM-14422-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:0005770"(late endosome)|go:"GO:0001701"(in utero embryonic development)|rgd:619949|refseq:NP_446247.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-RNO-9696270|reactome:R-RNO-9696273|interpro:IPR036770|rcsb pdb:7D6F|reactome:R-RNO-170984	go:"GO:0005768"(endosome)	no-uniprot-update:An amino acid sequence which is not represented in UniProt	-	figure legend:4A|agonist:"Nerve growth factor (NGF)"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2006/07/25	2014/10/16	-	rogid:HK13TDKSZUJSzqHU7w2EXSUoa1M10116	intact-crc:43A39535ECA3233F	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)