#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q58584 uniprotkb:Q58584 intact:EBI-980935|ensemblbacteria:AAB99185 intact:EBI-980935|ensemblbacteria:AAB99185 psi-mi:risc_metja(display_long)|uniprotkb:ribC(gene name)|psi-mi:ribC(display_short)|uniprotkb:MJ1184(locus name) psi-mi:risc_metja(display_long)|uniprotkb:ribC(gene name)|psi-mi:ribC(display_short)|uniprotkb:MJ1184(locus name) psi-mi:"MI:0114"(x-ray crystallography) Ramsperger et al. (2006) imex:IM-14441|pubmed:16272154 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-980956|rcsb pdb:2b98|rcsb pdb:2b99|imex:IM-14441-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002180(6,7-dimethyl-8-ribityllumazine synthase)|interpro:IPR006399(Riboflavin synthase, archaeal)|rcsb pdb:2B98|rcsb pdb:2B99|ensemblbacteria:AAB99185(transcript)|ensemblbacteria:MJ_1184(gene)|go:"GO:0004746"(riboflavin synthase activity)|go:"GO:0009231"(riboflavin biosynthetic process)|go:"GO:0009349"(riboflavin synthase complex)|rcsb pdb:4Y7J|rcsb pdb:4Y7K|rcsb pdb:5IM5|refseq:WP_010870697.1|interpro:IPR036467 interpro:IPR002180(6,7-dimethyl-8-ribityllumazine synthase)|interpro:IPR006399(Riboflavin synthase, archaeal)|rcsb pdb:2B98|rcsb pdb:2B99|ensemblbacteria:AAB99185(transcript)|ensemblbacteria:MJ_1184(gene)|go:"GO:0004746"(riboflavin synthase activity)|go:"GO:0009231"(riboflavin biosynthetic process)|go:"GO:0009349"(riboflavin synthase complex)|rcsb pdb:4Y7J|rcsb pdb:4Y7K|rcsb pdb:5IM5|refseq:WP_010870697.1|interpro:IPR036467 - - - complex-properties:"The complex was desribed as a pentamer of size (approximate) 80X80X45 Angstrom."|comment:"The binding substrate analog 6,7-dioxo-8-ribityllumazine (DORL) forms hydrogen bonds with the main chain gly41, Ile42, Glu97 and Asp44 of the active site of the protein. Hydrogen bonds are also observed between the O4 of DORL and His122 and O2 of DORL and Gln146. In the protein itself the Arg118 forms a salt bridge with Glu104."|figure legend:Figure 2C Table 1|3d-structure:"The protein complex contained one pentamer in an asymetric unit. Poor electron density was determined in the C terminal region of three subunits of the pentamer (residues 143-153). The pentamer had a size of 80X80X45A."|3d-resolution:2.3 A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/08/03 2014/10/16 rogid:ArQ54KgbqyBlR99Mpe3krchUgqc243232 rogid:ArQ54KgbqyBlR99Mpe3krchUgqc243232 intact-crc:BD4C3F2911B13C0C|rigid:dr6UAUWFQy4Bg+3Pzxq6jyaxJyc false - - 5 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)